Publikationer

Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli

Heidarian, Sheida; Hjort, Karin; Nicoloff, Hervé; Andersson, Dan I.

Ingår i mBio, 2026

• DOI för Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli
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Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Agnihotri, Sagar N.; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Windhager, Jonas et al.

Ingår i npj Digital Medicine, 2026

• DOI för Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections
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Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope

Buchholz, Florian; Upterworth, Lina M.; Tueffers, Leif; Groth, Espen E. et al.

Ingår i Nature Communications, 2026

• DOI för Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope
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The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing

Jonsson, Sofia; Guliaev, Andrei; Berryhill, Brandon A.; Andersson, Dan I. et al.

Ingår i Nature Communications, 2026

• DOI för The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing
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When Does Evidence Create a Moral Obligation to Depart from Antibiotic Guidelines?

Ancillotti, Mirko; Andersson, Dan I.; Sandegren, Linus

Ingår i American Journal of Bioethics, s. 109-111, 2026

• DOI för When Does Evidence Create a Moral Obligation to Depart from Antibiotic Guidelines?
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CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions

Hallström, Erik; Fatsis-Kavalopoulos, Nikos; Bimpis, Manos; Wählby, Carolina et al.

Ingår i PLOS Digital Health, 2025

• DOI för CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions
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Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections

Agnihotri, Sagar Narhari; Fatsis-Kavalopoulos, Nikos; Windhager, Jonas; Tenje, Maria et al.

Ingår i Science Advances, 2025

• DOI för Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections
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Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates

Lundvik, Hanna; Santini, Ramona; Altintop, Tugce Unalan; Ozenci, Volkan et al.

Ingår i Scientific Reports, 2025

• DOI för Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates
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Heteroresistance and clinical outcomes: much still to be understood – Authors' reply

Fatsis-Kavalopoulos, Nikos; Heyman, Gabriel; Hjort, Karin; Jonsson, Sofia et al.

Ingår i The Lancet Microbe, 2025

• DOI för Heteroresistance and clinical outcomes: much still to be understood – Authors' reply
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Host-Specific Adaptation of Legionella pneumophila to Single and Multiple Hosts

Moreno, Anaísa B.; Paranjape, Kiran; Cederblom, Martina; Kay, Elisabeth et al.

Ingår i Molecular biology and evolution, 2025

• DOI för Host-Specific Adaptation of Legionella pneumophila to Single and Multiple Hosts
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Influence of printing configuration on the resulting topology and antibacterial effectiveness of PVDF-graphene composites

Spanou, Antrea; Hjort, Karin; Welch, Ken; Andersson, Dan I. et al.

Ingår i Polymer testing, 2025

• DOI för Influence of printing configuration on the resulting topology and antibacterial effectiveness of PVDF-graphene composites
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Interspecies interaction alters the trajectory of antibiotic resistance evolution by amplifying negative fitness epistasis

Muzafar, Suraya; Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Ingår i The ISME Journal, 2025

• DOI för Interspecies interaction alters the trajectory of antibiotic resistance evolution by amplifying negative fitness epistasis
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Linoleic acid addition prevents Staphylococcus aureus biofilm formation on PMMA bone cement

Hong, Linglu; Hjort, Karin; Andersson, Dan; Persson, Cecilia

Ingår i Biofilm, 2025

• DOI för Linoleic acid addition prevents Staphylococcus aureus biofilm formation on PMMA bone cement
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Machine learning detection of heteroresistance in Escherichia coli

Guliaev, Andrei; Hjort, Karin; Rossi, Michele; Jonsson, Sofia et al.

Ingår i EBioMedicine, 2025

• DOI för Machine learning detection of heteroresistance in Escherichia coli
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Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Heyman, Gabriel; Jonsson, Sofia; Fatsis-Kavalopoulos, Nikos; Hjort, Karin et al.

Ingår i The Lancet Microbe, 2025

• DOI för Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
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Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida

Hughes, Abigail; Pelligand, Ludovic; Andersson, Dan I.; Mead, Andrew

Ingår i PLOS ONE, 2025

• DOI för Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida
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Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations

Sánchez-Hevia, Dione L.; Fatsis-Kavalopoulos, Nikolaos; Andersson, Dan I.

Ingår i Microbiology Spectrum, 2025

• DOI för Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations
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Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold

Fatsis-Kavalopoulos, Nikos; Kim, Yong Kyun; Chong, Yong Pil; Bae, Seongman et al.

Ingår i Nature Communications, 2025

• DOI för Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold
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Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids

Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Ingår i Microbiology Spectrum, 2024

• DOI för Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids
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Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

Pal, Ankita; Andersson, Dan I.

Ingår i Nature Communications, 2024

• DOI för Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
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Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)

Fatsis-Kavalopoulos, Nikos; Sánchez-Hevia, Dione; Andersson, Dan I.

Ingår i Journal of Antimicrobial Chemotherapy, s. 2394-2396, 2024

• DOI för Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)
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Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes

Babiker, Ahmed; Lohsen, Sarah; Van Riel, Julia; Hjort, Karin et al.

Ingår i JAC - Antimicrobial Resistance, 2024

• DOI för Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes
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High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes

Heidarian, Sheida; Guliaev, Andrei; Nicoloff, Hervé; Hjort, Karin et al.

Ingår i PLoS biology, 2024

• DOI för High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes
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Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Ingår i Scientific Reports, 2024

• DOI för Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
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Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism

Warsi, Omar M.; Upterworth, Lina M.; Breidenstein, Annika; Lustig, Ulrika et al.

Ingår i mBio, 2024

• DOI för Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism
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Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

Babina, Arianne M.; Kirsebom, Leif; Andersson, Dan I.

Ingår i RNA, s. 977-991, 2024

• DOI för Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations
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The strength of interspecies interaction in a microbial community determines its susceptibility to invasion

Muzafar, Suraya; Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Ingår i PLoS biology, 2024

• DOI för The strength of interspecies interaction in a microbial community determines its susceptibility to invasion
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Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance

Levin, Bruce R.; Berryhill, Brandon A.; Gil-Gil, Teresa; Manuel, Joshua A. et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance
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Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance

Nicoloff, Hervé; Hjort, Karin; Andersson, Dan I.; Wang, Helen

Ingår i Nature Communications, 2024

• DOI för Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance
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Within-species variability of antibiotic interactions in Gram-negative bacteria

Tang, Po-Cheng; Sánchez-Hevia, Dione; Westhoff, Sanne; Fatsis-Kavalopoulos, Nikos et al.

Ingår i mBio, 2024

• DOI för Within-species variability of antibiotic interactions in Gram-negative bacteria
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Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution

Fait, Anaelle; Andersson, Dan I.; Ingmer, Hanne

Ingår i Current Biology, 2023

• DOI för Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution
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Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli

Nair, Ramith R.; Andersson, Dan I.

Ingår i Communications Biology, 2023

• DOI för Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli
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Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations

Pereira, Catia; Warsi, Omar M.; Andersson, Dan I.

Ingår i Molecular biology and evolution, 2023

• DOI för Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations
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Rescue of Escherichia coli auxotrophy by de novo small proteins

Babina, Arianne M.; Surkov, Serhiy; Ye, Weihua; Jerlström-Hultqvist, Jon et al.

Ingår i eLIFE, 2023

• DOI för Rescue of Escherichia coli auxotrophy by de novo small proteins
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Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities

Warsi, Omar M.; Gedda, Lars; Edwards, Katarina; Andersson, Dan I.

Ingår i FEMS Microbiology Ecology, 2023

• DOI för Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities
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A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms

Tang, Po-Cheng; Eriksson, Olle; Sjögren, Josefin; Fatsis-Kavalopoulos, Nikos et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2022

• DOI för A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms
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Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Hjort, Karin; Fermér, Elin; Tang, Po-Cheng; Andersson, Dan I.

Ingår i mBio, 2022

• DOI för Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment

Hjort, Karin; Jurén, Pontus; Toro, Juan Carlos; Hoffner, Sven et al.

Ingår i Journal of Infectious Diseases, s. 1011-1020, 2022

• DOI för Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment
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Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

Ingår i PLoS biology, 2022

• DOI för Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline
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Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies

Zaborskyte, Greta; Wistrand-Yuen, Erik; Hjort, Karin; Andersson, Dan I. et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2022

• DOI för Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies
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Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

Fatsis-Kavalopoulos, Nikos; Roelofs, Lex; Andersson, Dan I.

Ingår i EBioMedicine, 2022

• DOI för Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates
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Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study

Howard-Anderson, Jessica; Davis, Michelle; Page, Alexander M.; Bower, Chris W. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 793-798, 2022

• DOI för Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study

The physiology and genetics of bacterial responses to antibiotic combinations

Roemhild, Roderich; Bollenbach, Tobias; Andersson, Dan I.

Ingår i Nature Reviews Microbiology, s. 478-490, 2022

• DOI för The physiology and genetics of bacterial responses to antibiotic combinations

A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

Rao, Komal Umashankar; Henderson, Domhnall Iain; Krishnan, Nitya; Puthia, Manoj et al.

Ingår i Scientific Reports, 2021

• DOI för A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy
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A novel type of colistin resistance genes selected from random sequence space

Knopp, Michael; Babina, Arianne M.; Gudmundsdottir, Jonina S.; Douglass, Martin, V et al.

Ingår i PLOS Genetics, 2021

• DOI för A novel type of colistin resistance genes selected from random sequence space
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An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance

Ancillotti, Mirko; Eriksson, Stefan; Godskesen, Tove; Andersson, Dan I. et al.

Ingår i Public Health Ethics, s. 1-11, 2021

• DOI för An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance
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Mechanisms and therapeutic potential of collateral sensitivity to antibiotics

Roemhild, Roderich; Andersson, Dan I.

Ingår i PLoS Pathogens, 2021

• DOI för Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
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Metabolic fitness landscapes predict the evolution of antibiotic resistance

Pinheiro, Fernanda; Warsi, Omar M.; Andersson, Dan I.; Laessig, Michael

Ingår i Nature Ecology & Evolution, s. 677-687, 2021

• DOI för Metabolic fitness landscapes predict the evolution of antibiotic resistance

Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment

Atterby, Clara; Nykvist, Marie; Lustig, Ulrika; Andersson, Dan I. et al.

Ingår i Antimicrobial Agents and Chemotherapy, 2021

• DOI för Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment

Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family

Guo, Xiaohu; Söderholm, Annika; Kanchugal Puttaswamy, Sandesh; Isaksen, Geir V et al.

Ingår i eLIFE, 2021

• DOI för Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family
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