Publications

Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence

Abdalaal, Hind; Pundir, Shreya; Ge, Xueliang; Sanyal, Suparna et al.

Part of Molecular biology and evolution, p. 2918-2930, 2020

• DOI for Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence
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Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence

Lundin, Erik; Näsvall, Joakim; Andersson, Dan I.

Part of Frontiers in Microbiology, 2020

• DOI for Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence
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Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA

Knöppel, Anna; Andersson, Dan I; Näsvall, Joakim

Part of Frontiers in Microbiology, 2020

• DOI for Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA
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Selection for novel metabolic capabilities in Salmonella enterica

Warsi, Omar M.; Lundin, Erik; Lustig, Ulrika; Näsvall, Joakim et al.

Part of Evolution, p. 990-1000, 2019

• DOI for Selection for novel metabolic capabilities in Salmonella enterica
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Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA

Lundin, Erik; Tang, Po-Cheng; Guy, Lionel; Näsvall, Joakim et al.

Part of Molecular biology and evolution, p. 704-718, 2018

• DOI for Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA
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Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica

Knöppel, Anna; Knopp, Michael; Albrecht, Lisa M; Lundin, Erik et al.

Part of Frontiers in Microbiology, 2018

• DOI for Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica
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Structural mechanism of AadA, a dual specificity aminoglycoside adenylyltransferase from Salmonella enterica

Stern, Ana Laura; Van der Verren, Sander Egbert; Kanchugal Puttaswamy, Sandesh; Näsvall, Joakim et al.

Part of Journal of Biological Chemistry, p. 11481-11490, 2018

• DOI for Structural mechanism of AadA, a dual specificity aminoglycoside adenylyltransferase from Salmonella enterica
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Direct and Inverted Repeat stimulated excision (DIRex): Simple, single-step, and scar-free mutagenesis of bacterial genes

Näsvall, Joakim

Part of PLOS ONE, 2017

• DOI for Direct and Inverted Repeat stimulated excision (DIRex): Simple, single-step, and scar-free mutagenesis of bacterial genes
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Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria

Näsvall, Joakim; Knöppel, Anna; Andersson, Dan I.

Part of Nucleic Acids Research, 2017

• DOI for Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria
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Evolution of antibiotic resistance without antibiotic exposure

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Part of Antimicrobial Agents and Chemotherapy, 2017

• DOI for Evolution of antibiotic resistance without antibiotic exposure
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Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes

Newton, Matilda S.; Guo, Xiaohu; Söderholm, Annika; Näsvall, Joakim et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 4727-4732, 2017

• DOI for Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes

Compensating the fitness costs of synonymous mutations

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Part of Molecular biology and evolution, p. 1461-1477, 2016

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Evolution of New Functions De Novo and from Preexisting Genes

Andersson, Dan I.; Jerlström-Hultqvist, Jon; Näsvall, Joakim

Part of Cold Spring Harbor Perspectives in Biology, 2015

• DOI for Evolution of New Functions De Novo and from Preexisting Genes

Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase

Chen, Yang; Näsvall, Joakim; Wu, Shiying; Andersson, Dan I. et al.

Part of Acta Crystallographica Section D, p. 2267-2277, 2015

• DOI for Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase
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Two-step Ligand Binding in a (βα)8 Barrel Enzyme: Substrate-bound Structures Shed New Light on the Catalytic Cycle of HisA

Söderholm, Annika; Guo, Xiaohu; Newton, Matilda S.; Evans, Gary B. et al.

Part of Journal of Biological Chemistry, p. 24657-24668, 2015

• DOI for Two-step Ligand Binding in a (βα)8 Barrel Enzyme: Substrate-bound Structures Shed New Light on the Catalytic Cycle of HisA

Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria

Knöppel, Anna; Lind, Peter A.; Lustig, Ulrika; Näsvall, Joakim et al.

Part of Molecular biology and evolution, p. 1220-1227, 2014

• DOI for Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria

Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Näsvall, Joakim; Sun, Lei; Roth, John R.; Andersson, Dan I.

Part of Science, p. 384-387, 2012

• DOI for Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Activation of cryptic aminoglycoside resistance in Salmonella enterica

Koskiniemi, Sanna; Pränting, Maria; Gullberg, Erik; Näsvall, Joakim et al.

Part of Molecular Microbiology, p. 1464-1478, 2011

• DOI for Activation of cryptic aminoglycoside resistance in Salmonella enterica