Our current publications

Diffusion of Affibody molecules in extracellular matrix mimetic hydrogels and the effect of albumin binding

Parlow, Julia; Sandegren, Anna; Güler, Rezan; Karlberg, Ida et al.

Part of International Journal of Biological Macromolecules, 2026

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• DOI for Diffusion of Affibody molecules in extracellular matrix mimetic hydrogels and the effect of albumin binding
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Structural determination of self-assembled aggregates formed by a therapeutic cyclical peptide and an ionic surfactant in aqueous solution

Brunzell, Ellen; Kim Högström, Yumi; López Hernández, Marcos; Skov Pedersen, Jan et al.

Part of Journal of Colloid and Interface Science, 2026

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• DOI for Structural determination of self-assembled aggregates formed by a therapeutic cyclical peptide and an ionic surfactant in aqueous solution
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A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats

Niessen, Janis; Arendt, Nathalie; Sjöblom, Markus; Dubbelboer, Ilse R. et al.

Part of European journal of pharmaceutics and biopharmaceutics, 2025

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• DOI for A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats
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A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary

Lindman, Jens; Puthiyaparambath, Sharathna; Gising, Johan; Odell, Luke R. et al.

Part of Synlett, p. 2009-2013, 2025

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• DOI for A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary
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A Multicomponent aza-Prins Strategy for the Diastereoselective Synthesis of Piperidine-Fused Dihydroquinazolinones

Dybeck, Lovisa; Baudoin, Morgane; Odell, Luke R.

Part of European Journal of Organic Chemistry, 2025

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• DOI for A Multicomponent aza-Prins Strategy for the Diastereoselective Synthesis of Piperidine-Fused Dihydroquinazolinones
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A Phase I/IIa Clinical Trial to Evaluate Safety and Adrenal Uptake of Para-Chloro-2-[¹⁸F]Fluoroethyletomidate in Healthy Volunteers and Patients with Primary Aldosteronism

Gillett, Daniel; Senanayake, Russell; MacFarlane, James; Bashari, Waiel et al.

Part of Journal of Nuclear Medicine, p. 434-440, 2025

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• DOI for A Phase I/IIa Clinical Trial to Evaluate Safety and Adrenal Uptake of Para-Chloro-2-[¹⁸F]Fluoroethyletomidate in Healthy Volunteers and Patients with Primary Aldosteronism

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

Tricht, Ewoud van; Sänger-van de Griend, Cari

Part of Electrophoresis, p. 933-953, 2025

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• DOI for A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development
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A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Olaniran Håkansson, Esther; Zelepukin, Ivan V.; Obeid, Karim; Bitzios, Athanasios et al.

Part of EJNMMI Research, 2025

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• DOI for A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression
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A universal language for finding mass spectrometry data patterns

Damiani, Tito; Jarmusch, Alan K.; Aron, Allegra T.; Petras, Daniel et al.

Part of Nature Methods, 2025

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• DOI for A universal language for finding mass spectrometry data patterns
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Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure-Activity Relationship

Safratova, Marcela; Chen, Yu-Li; Hostalkova, Anna; Chlebek, Jakub et al.

Part of Influenza and Other Respiratory Viruses, 2025

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• DOI for Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure-Activity Relationship
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Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease

Kaya, Ibrahim; Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik et al.

Part of npj Parkinson's Disease, 2025

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• DOI for Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
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Canagliflozin: Pharmacokinetics, tolerability and glucose/insulin effects of supratherapeutic doses in healthy horses

Michanek, Peter; Bröjer, Johan; Lilliehöök, Inger; Fjordbakk, Cathrine et al.

Part of The Veterinary Journal, 2025

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• DOI for Canagliflozin: Pharmacokinetics, tolerability and glucose/insulin effects of supratherapeutic doses in healthy horses
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Carboxylate and coordination influence on the formation of an active RuV Oxo species

El-Abid, Jamal; Dorst, Kevin M.; Inge, Andrew K.; Verho, Oscar et al.

Part of Scientific Reports, 2025

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• DOI for Carboxylate and coordination influence on the formation of an active RuV Oxo species
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Chemical characterization of C₃₁ sterols from sponges and Neoproterozoic fossil sterane counterparts

Shawar, Lubna; Love, Gordon D.; Uveges, Benjamin T.; Zumberge, J. Alex et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2025

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• DOI for Chemical characterization of C₃₁ sterols from sponges and Neoproterozoic fossil sterane counterparts
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Cobaltaelectro-catalyzed C–H acyloxylation of aromatic and vinylic amide derivatives at room temperature

Sitdikov, Ruzal; Nikolaienko, Pavlo; Meyer, Luca; Verho, Oscar

Part of Chemical Communications, p. 16946-16949, 2025

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• DOI for Cobaltaelectro-catalyzed C–H acyloxylation of aromatic and vinylic amide derivatives at room temperature
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Connectivity and Adaptation Patterns of the Deep-Sea Ground-Forming Sponge Geodia hentscheli Across Its Entire Distribution

Taboada, Sergi; Diez-Vives, Cristina; Turon, Marta; Belen Arias, Maria et al.

Part of Molecular biology and evolution, 2025

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• DOI for Connectivity and Adaptation Patterns of the Deep-Sea Ground-Forming Sponge Geodia hentscheli Across Its Entire Distribution
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Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides

Valli, Dylan; Ooi, Saik Ann; Kaya, Ibrahim; Thomassen, Asger Berg et al.

Part of Biochemistry, p. 2583-2595, 2025

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• DOI for Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
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Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes

Söderström, Marcus; Olaniran Håkansson, Esther; Odell, Luke R.

Part of Chemical Communications, p. 145-148, 2025

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• DOI for Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes
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Designed Ankyrin Repeat Protein-Mediated Peptide Nucleic Acid-Based Pretargeting: A Proof-of-Principle Study

Oroujeni, Maryam; Westerlund, Kristina; Papalanis, Eleftherios; van Deventer, Alexander et al.

Part of Journal of Nuclear Medicine, p. 1105-1111, 2025

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• DOI for Designed Ankyrin Repeat Protein-Mediated Peptide Nucleic Acid-Based Pretargeting: A Proof-of-Principle Study

Development and in vitro evaluation of lipodisks optimized for co-delivery of chemotherapeutic drugs and membranolytic anticancer peptides

Silva, Luis; Ali, Sajid; Gedda, Lars; Agmo Hernández, Víctor et al.

Part of Journal of Colloid and Interface Science, 2025

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• DOI for Development and in vitro evaluation of lipodisks optimized for co-delivery of chemotherapeutic drugs and membranolytic anticancer peptides
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Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Haglöf, Jakob; Nilsson, Jenny M.; Ludvigsson, Jufang Wu

Part of Journal of Separation Science, 2025

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• DOI for Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
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DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Part of Scientific Reports, 2025

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• DOI for DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Diffusion of macromolecules in extracellular matrix mimetic hydrogels: effect of size and charge

Parlow, Julia; Pet, Eva; Smirnova, Anna; Mojumdar, Enamul et al.

Part of European Journal of Pharmaceutical Sciences, 2025

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• DOI for Diffusion of macromolecules in extracellular matrix mimetic hydrogels: effect of size and charge
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Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance

Hornyak, Marta; Kula-Maximenko, Monika; Miszalski, Zbigniew; Nilsson, Anna et al.

Part of Scientific Reports, 2025

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• DOI for Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance
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Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts

Mortensen, Anja; Berglund, Hanna; Jha, Preeti; Stenman, Adam et al.

Part of Molecular Cancer Therapeutics, p. 753-762, 2025

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• DOI for Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
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Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths

Aro, Olli-Pekka; Casula, Victor; Hänninen, Nina E.; Karjalainen, Jouni et al.

Part of Heliyon, 2025

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• DOI for Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths
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Emergence of pseudoresonance in high-intensity resonant inelastic x-ray scattering

Son, Sang-Kil; Baumann, Thomas M.; Pedersen, Jacob; Budewig, Laura et al.

Part of Physical Review A: covering atomic, molecular, and optical physics and quantum information, 2025

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• DOI for Emergence of pseudoresonance in high-intensity resonant inelastic x-ray scattering
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Enhanced Structural Understanding of Dissolved Organic Matter through Comparative LC/MS2 Analysis with Synthetic Carboxylate Rich Alicyclic Molecules

Hawkes, Jeffrey A.; Flygare, Agnes D.; Moodie, Lindon W. K.; Craig, Alexander J.

Part of Analytical Chemistry, p. 18612-18620, 2025

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• DOI for Enhanced Structural Understanding of Dissolved Organic Matter through Comparative LC/MS2 Analysis with Synthetic Carboxylate Rich Alicyclic Molecules
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Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?

Kanellopoulos, Panagiotis; Yu, Quanyi; Abouzayed, Abouzayed; Bezverkhniaia, Ekaterina et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?
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Exploring the Role of Photolysis in the Aquatic Fate of Antimicrobial Transformation Products: Implications for One Health

Löffler, Paul; Henschel, Henning; Ugolini, Valentina; Flores Quintana, Harold et al.

Part of ACS - ES & T Water, p. 4112-4119, 2025

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• DOI for Exploring the Role of Photolysis in the Aquatic Fate of Antimicrobial Transformation Products: Implications for One Health
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Extending the shelf life of 68Ge/68Ga generators via preconcentration of [68Ga]GaCl3 for preclinical application

Mallapura, Hemantha; Eriksson, Olof

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Extending the shelf life of 68Ge/68Ga generators via preconcentration of [68Ga]GaCl3 for preclinical application
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First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT

Bjareback, Annie; Jonmarker, Olof; Tzortzakakis, Antonios; Jussing, Emma et al.

Part of EJNMMI Research, 2025

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• DOI for First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT
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Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology

Schlein, Eva; Lopes van den Broek, Sara; Dallas, Tiffany; Andersson, Ken G. et al.

Part of ACS Pharmacology & Translational Science, p. 2804-2813, 2025

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• DOI for Fluorine-18 ImmunoPET Imaging of Antibody Brain Kinetics and Amyloid-Beta Pathology
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Ga-68-Labeled Affibody Molecule-Based Radiopharmaceutical Targeting Platelet Derived Growth Factor Receptor Beta for Detection of Active Fibrosis in Patients with Myocardial Infarction

Velikyan, Irina; Grinnemo, Karl-Henrik; Flodin, Viktor; James, Stefan et al.

Part of Pharmaceuticals, 2025

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• DOI for Ga-68-Labeled Affibody Molecule-Based Radiopharmaceutical Targeting Platelet Derived Growth Factor Receptor Beta for Detection of Active Fibrosis in Patients with Myocardial Infarction
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Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis

Haglöf, Jakob; Bivehed, Erik; Sänger-van de Griend, Cari

Part of Talanta, 2025

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• DOI for Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
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Ghost peaks simulation and reduction in high-resolution echo-planar spectroscopic imaging with flyback readout

Weis, Jan; Babos, Magor; Selvaraju, Ram Kumar

Part of Scientific Reports, 2025

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• DOI for Ghost peaks simulation and reduction in high-resolution echo-planar spectroscopic imaging with flyback readout
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Hydrogel-Mediated Sustained Delivery of Corneal Epithelial Extracellular Vesicles: A Strategy for Enhanced Corneal Regeneration

Rosenquist Lybecker, Jenny; Van de Ven, Ann; Braesch-Andersen, Ken; Juriga, David et al.

Part of ACS Omega, p. 37081-37095, 2025

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• DOI for Hydrogel-Mediated Sustained Delivery of Corneal Epithelial Extracellular Vesicles: A Strategy for Enhanced Corneal Regeneration
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Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules

Tolmachev, Vladimir M.; Papalanis, Eleftherios; Bezverkhniaia, Ekaterina A.; Rosly, Alia Hani et al.

Part of ACS Pharmacology & Translational Science, p. 706-717, 2025

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• DOI for Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules
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Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Sjolund, Marie; Rosendal, Thomas; Wallgren, Per; Pringle, Maerit et al.

Part of Acta Veterinaria Scandinavica, 2025

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• DOI for Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs
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Improving GRPR-targeting peptides for radiotheranostics application: insights from chelator modifications and α-methyl-L tryptophan substitution.

Obeid, Karim; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir M.; Orlova, Anna et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Improving GRPR-targeting peptides for radiotheranostics application: insights from chelator modifications and α-methyl-L tryptophan substitution.
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In Silico Frontiers Shaping the Next Generation of Transformation Product Prediction and Toxicological Assessment

Löffler, Paul; Schymanski, Emma L.; Henschel, Henning; Lai, Foon Yin

Part of Environmental Science and Technology, p. 19095-19106, 2025

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• DOI for In Silico Frontiers Shaping the Next Generation of Transformation Product Prediction and Toxicological Assessment
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Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran Håkansson, Esther et al.

Part of Neuroscience Letters, 2025

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• DOI for Insulin-regulated aminopeptidase inhibitor C9 restores cellular activity in methadone-damaged primary cell cultures
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Interaction of Sodium Polystyrenesulfonate with Fluorinated Ionic Surfactant of Opposite Charge

Turk, Matevz; Kogej, Ksenija; Hansson, Per

Part of Langmuir, p. 26673-26682, 2025

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• DOI for Interaction of Sodium Polystyrenesulfonate with Fluorinated Ionic Surfactant of Opposite Charge
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Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)

Miszczak, Rebecca; Slazak, Blazej; Sychta, Klaudia; Göransson, Ulf et al.

Part of Plants, 2025

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• DOI for Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)
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Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics

Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Tolmachev, Vladimir M. et al.

Part of European Journal of Pharmaceutical Sciences, 2025

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• DOI for Linker modifications in radiolabeled RM26-based antagonists to gastrin-releasing peptide receptor (GRPR) improved tracers' pharmacokinetics
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Part of Journal of Colloid and Interface Science, p. 287-300, 2025

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• DOI for Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin.

Kopsida, Maria; Regtop, Lotta; Lennernäs, Hans; Hedeland, Mikael et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, p. 117012, 2025

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• DOI for Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin.
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Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia

Engskog-Vlachos, Pinelopi; Engskog, Mikael K R; Skandik, Martin; Grabert, Kathleen et al.

Part of Journal of Neurochemistry, 2025

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• DOI for Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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Novel Macrocyclic Peptidomimetics Targeting the Insulin-Regulated Aminopeptidase (IRAP): Design, Synthesis and Evaluation

Olaniran Håkansson, Esther; Balestri, Lorenzo Jacopo Ilic; Puthiyaparambath, Sharathna; Moes, Sebastian et al.

Part of RSC Medicinal chemistry, p. 5059-5069, 2025

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• DOI for Novel Macrocyclic Peptidomimetics Targeting the Insulin-Regulated Aminopeptidase (IRAP): Design, Synthesis and Evaluation
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Observation of an Associative State in Aqueous Hydroxide

Yin, Zhong; Krasnov, Pavel; Thürmer, Stephan; Chatzigeorgiou, Evanthia et al.

Part of Journal of the American Chemical Society, p. 9190-9197, 2025

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• DOI for Observation of an Associative State in Aqueous Hydroxide
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