Our current publications

A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats

Niessen, Janis; Arendt, Nathalie; Sjöblom, Markus; Dubbelboer, Ilse R. et al.

Part of European journal of pharmaceutics and biopharmaceutics, 2025

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• DOI for A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats
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A Phase I/IIa Clinical Trial to Evaluate Safety and Adrenal Uptake of Para-Chloro-2-[¹⁸F]Fluoroethyletomidate in Healthy Volunteers and Patients with Primary Aldosteronism

Gillett, Daniel; Senanayake, Russell; MacFarlane, James; Bashari, Waiel et al.

Part of Journal of Nuclear Medicine, p. 434-440, 2025

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• DOI for A Phase I/IIa Clinical Trial to Evaluate Safety and Adrenal Uptake of Para-Chloro-2-[¹⁸F]Fluoroethyletomidate in Healthy Volunteers and Patients with Primary Aldosteronism

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

Tricht, Ewoud van; Sänger ‐ van de Griend, Cari E.

Part of Electrophoresis, 2025

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• DOI for A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

Carboxylate and coordination influence on the formation of an active RuV Oxo species

El-Abid, Jamal; Dorst, Kevin M.; Inge, Andrew K.; Verho, Oscar et al.

Part of Scientific Reports, 2025

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• DOI for Carboxylate and coordination influence on the formation of an active RuV Oxo species
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Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes

Söderström, Marcus; Olaniran Håkansson, Esther; Odell, Luke R.

Part of Chemical Communications, p. 145-148, 2025

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• DOI for Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes
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DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Part of Scientific Reports, 2025

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• DOI for DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts

Mortensen, Anja; Berglund, Hanna; Jha, Preeti; Stenman, Adam et al.

Part of Molecular Cancer Therapeutics, p. 753-762, 2025

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• DOI for Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
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Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths

Aro, Olli-Pekka; Casula, Victor; Hänninen, Nina E.; Karjalainen, Jouni et al.

Part of Heliyon, 2025

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• DOI for Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths

Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?

Kanellopoulos, Panagiotis; Yu, Quanyi; Abouzayed, Abouzayed; Bezverkhniaia, Ekaterina et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?
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Exploring the Role of Photolysis in the Aquatic Fate of Antimicrobial Transformation Products: Implications for One Health

Löffler, Paul; Henschel, Henning; Ugolini, Valentina; Flores Quintana, Harold et al.

Part of ACS - ES & T Water, 2025

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• DOI for Exploring the Role of Photolysis in the Aquatic Fate of Antimicrobial Transformation Products: Implications for One Health

First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT

Bjareback, Annie; Jonmarker, Olof; Tzortzakakis, Antonios; Jussing, Emma et al.

Part of EJNMMI Research, 2025

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• DOI for First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT
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Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules

Tolmachev, Vladimir M.; Papalanis, Eleftherios; Bezverkhniaia, Ekaterina A.; Rosly, Alia Hani et al.

Part of ACS Pharmacology & Translational Science, p. 706-717, 2025

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• DOI for Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules
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Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Sjolund, Marie; Rosendal, Thomas; Wallgren, Per; Pringle, Maerit et al.

Part of Acta Veterinaria Scandinavica, 2025

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• DOI for Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs
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Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)

Miszczak, Rebecca; Slazak, Blazej; Sychta, Klaudia; Göransson, Ulf et al.

Part of Plants, 2025

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• DOI for Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Part of Journal of Colloid and Interface Science, p. 287-300, 2025

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• DOI for Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Observation of an Associative State in Aqueous Hydroxide

Yin, Zhong; Krasnov, Pavel; Thürmer, Stephan; Chatzigeorgiou, Evanthia et al.

Part of Journal of the American Chemical Society, p. 9190-9197, 2025

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• DOI for Observation of an Associative State in Aqueous Hydroxide
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Peak Integration of Electropherograms in GMP and Research Labs: Navigating Increased Scrutiny Amid Data Integrity Audits and Inspections

Blanc, Timothy; Wätzig, Hermann; Sänger - van de Griend, Cari

Part of Electrophoresis, 2025

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• DOI for Peak Integration of Electropherograms in GMP and Research Labs: Navigating Increased Scrutiny Amid Data Integrity Audits and Inspections

Pharmacokinetics and Alterations in Glucose and Insulin Levels After a Single Dose of Canagliflozin in Healthy Icelandic Horses

Michanek, Peter; Bröjer, Johan; Lilliehöök, Inger; Fjordbakk, Cathrine T et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 41-49, 2025

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• DOI for Pharmacokinetics and Alterations in Glucose and Insulin Levels After a Single Dose of Canagliflozin in Healthy Icelandic Horses
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Regioselective Palladaelectro-Catalyzed Chlorination of Arenes in an Undivided Cell

Ponra, Sudipta; Sitdikov, Ruzal; Calis, Alyssio; Verho, Oscar

Part of Advanced Synthesis and Catalysis, 2025

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• DOI for Regioselective Palladaelectro-Catalyzed Chlorination of Arenes in an Undivided Cell
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Part of Intensive Care Medicine Experimental, 2025

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• DOI for Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Selection of the optimal chelator for labeling of DARPin Ec1 with gallium-68 for PET imaging of EpCAM expression

Vorobyeva, Anzhelika; Ud-din, Moeen; Schulga, Alexey; Konovalova, Elena et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Selection of the optimal chelator for labeling of DARPin Ec1 with gallium-68 for PET imaging of EpCAM expression
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Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [^99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study

Medvedeva, Anna; Chernov, Vladimir; Larkina, Maria; Rybina, Anastasiya et al.

Part of ACS Pharmacology & Translational Science, p. 736-747, 2025

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• DOI for Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [^99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study
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Smartphone-assisted fluorescent film based on the Flu grafted on Eu-MOF for real-time monitoring of fresh-cut fruit freshness

Zhang, Zhepeng; Gao, Mingjie; Zhang, Liang; Li, Jiangbo et al.

Part of Biosensors & bioelectronics, 2025

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• DOI for Smartphone-assisted fluorescent film based on the Flu grafted on Eu-MOF for real-time monitoring of fresh-cut fruit freshness

Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size

Forooqi Motlaq, Vahid; Gedda, Lars; Edwards, Katarina; Doutch, James et al.

Part of Journal of Colloid and Interface Science, p. 1008-1018, 2025

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• DOI for Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size
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Synthesis and In Vitro Profiling of Psilocin Derivatives: Improved Stability and Synthetic Properties

Eklund, Julia; Bremberg, Ulf; Larsson, Jessica; Torkelsson, Edvard et al.

Part of Journal of Medicinal Chemistry, p. 7153-7165, 2025

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• DOI for Synthesis and In Vitro Profiling of Psilocin Derivatives: Improved Stability and Synthetic Properties
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Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
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Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Spiegelberg, Diana; Hwang, Le-Ann; Pua, Khian Hong; Kumar, Sashwini Chandra et al.

Part of Scientific Reports, 2025

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• DOI for Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools
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The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships

Fernow, Josepine; Olliver, Marie; Couet, William; Lagrange, Sophie et al.

Part of Nature reviews. Drug discovery, p. 1-2, 2025

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• DOI for The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships
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The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering

Gråsjö, Johan; Persson, Ann-Sofie; Alderborn, Göran; Frenning, Göran et al.

Part of Powder Technology, 2025

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• DOI for The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering
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¹⁸F-labelling of nitrogen-containing aryl boronates: anti-cancer drug melflufen as a case study

Bajerke, Kevin; Lehmann, Fredrik; Antoni, Gunnar; Szabó, Kálmán J.

Part of Organic Chemistry Frontiers, p. 6411-6417, 2024

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• DOI for ¹⁸F-labelling of nitrogen-containing aryl boronates: anti-cancer drug melflufen as a case study
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A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids

Grad, Philipp; Edwards, Katarina; Gedda, Lars; Agmo Hernández, Víctor

Part of Biochimica et Biophysica Acta - Biomembranes, 2024

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• DOI for A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids
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A film-like SERS aptasensor for sensitive detection of patulin based on GO@Au nanosheets

Xue, Shanshan; Yin, Limei; Gao, Shipeng; Zhou, Ruiyun et al.

Part of Food Chemistry, 2024

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• DOI for A film-like SERS aptasensor for sensitive detection of patulin based on GO@Au nanosheets

A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration

Wanselius, Marcus; Abrahmsen-Alami, Susanna; Hanafy, Belal I.; Mazza, Mariarosa et al.

Part of International Journal of Pharmaceutics, 2024

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• DOI for A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration
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A Simple and Cost-Effective FeCl₃-Catalyzed Functionalization of Cellulose Nanofibrils: Toward Adhesive Nanocomposite Materials for Medical Implants

Tikhomirov, Evgenii; Franconetti, Antonio; Johansson, Mathias; Sandstrom, Corine et al.

Part of ACS Applied Materials and Interfaces, p. 30385-30395, 2024

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• DOI for A Simple and Cost-Effective FeCl₃-Catalyzed Functionalization of Cellulose Nanofibrils: Toward Adhesive Nanocomposite Materials for Medical Implants

A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels

Al-Tikriti, Yassir; Hansson, Per

Part of Colloids and Surfaces A, 2024

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• DOI for A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels
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Advancements in Microfluidic Cassette-Based iMiDEV^TM Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline

Mallapura, Hemantha; Tanguy, Laurent; Mahfuz, Samin; Bylund, Lovisa et al.

Part of Pharmaceuticals, 2024

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• DOI for Advancements in Microfluidic Cassette-Based iMiDEV^TM Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline
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Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Part of ACS Pharmacology & Translational Science, p. 3228-3240, 2024

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• DOI for Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
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Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Part of Acta neuropathologica communications, 2024

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• DOI for Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
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Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids

Nilsson, Jenny M.; Balgoma, David; Pettersson, Curt; Lennernäs, Hans et al.

Part of Analytica Chimica Acta, 2024

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• DOI for Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids
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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

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• DOI for Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Part of Journal of Neurochemistry, p. 2601-2610, 2024

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• DOI for Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Are we neglecting MERS-CoV during COVID-19 pandemic: a need for refocusing on surveillance of the deadly MERS-CoV infection

Mallhi, Tauqeer Hussain; Khan, Yusra Habib; Salman, Muhammad; Butt, Muhammad Hammad

Part of Clinical Microbiology and Infection, p. 256-257, 2024

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• DOI for Are we neglecting MERS-CoV during COVID-19 pandemic: a need for refocusing on surveillance of the deadly MERS-CoV infection

Assessment of spectral ghost artifacts in echo-planar spectroscopic micro-imaging with flyback readout

Weis, Jan; Babos, Magor; Estrada, Sergio; Selvaraju, Ram Kumar

Part of Scientific Reports, 2024

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• DOI for Assessment of spectral ghost artifacts in echo-planar spectroscopic micro-imaging with flyback readout
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Atypical Complications during the Course of COVID-19: A Comprehensive Review

Mallhi, Tauqeer Hussain; Safdar, Aqsa; Butt, Muhammad Hammad; Salman, Muhammad et al.

Part of Medicina, 2024

Article, review/survey

• DOI for Atypical Complications during the Course of COVID-19: A Comprehensive Review
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Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Part of European Journal of Medicinal Chemistry Reports, 2024

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• DOI for Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
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Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization

Popov, Anton L.; Kolmanovich, Danil D.; Chukavin, Nikita N.; Zelepukin, Ivan V. et al.

Part of Molecules, 2024

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• DOI for Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
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Co-complexes on modified graphite surface for steady green hydrogen production from water at neutral pH

Toledo-Carrillo, Esteban A.; Garcia-Rodriguez, Mario; Morallon, Emilia; Cazorla-Amoros, Diego et al.

Part of Frontiers in Chemistry, 2024

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• DOI for Co-complexes on modified graphite surface for steady green hydrogen production from water at neutral pH
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Coiled-coil scallops (Chlamys farreri) peptide hydrogel with metal ionic and temperature tunable assembly

Wu, Di; Wu, Chao; Ma, Wuchao; Wang, Zhenyu et al.

Part of Food Chemistry, 2024

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• DOI for Coiled-coil scallops (Chlamys farreri) peptide hydrogel with metal ionic and temperature tunable assembly

Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Larkina, Maria; Varvashenya, Ruslan; Yuldasheva, Feruza; Plotnikov, Evgenii et al.

Part of Molecular Pharmaceutics, p. 1919-1932, 2024

Article in journal

• DOI for Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Oroujeni, Maryam; Carlqvist, Matilda; Ryer, Eva; Orlova, Anna et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2024

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• DOI for Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
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