Our current publications

Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes

Söderström, Marcus; Olaniran Håkansson, Esther; Odell, Luke R.

Part of Chemical Communications, p. 145-148, 2025

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• DOI for Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes
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DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Part of Scientific Reports, 2025

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• DOI for DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?

Kanellopoulos, Panagiotis; Yu, Quanyi; Abouzayed, Abouzayed; Bezverkhniaia, Ekaterina et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI for Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?
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First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT

Bjareback, Annie; Jonmarker, Olof; Tzortzakakis, Antonios; Jussing, Emma et al.

Part of EJNMMI Research, 2025

Article in journal

• DOI for First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT
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Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)

Miszczak, Rebecca; Slazak, Blazej; Sychta, Klaudia; Göransson, Ulf et al.

Part of Plants, 2025

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• DOI for Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Part of Journal of Colloid and Interface Science, p. 287-300, 2025

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• DOI for Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Part of Intensive Care Medicine Experimental, 2025

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• DOI for Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Smartphone-assisted fluorescent film based on the Flu grafted on Eu-MOF for real-time monitoring of fresh-cut fruit freshness

Zhang, Zhepeng; Gao, Mingjie; Zhang, Liang; Li, Jiangbo et al.

Part of Biosensors & bioelectronics, 2025

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• DOI for Smartphone-assisted fluorescent film based on the Flu grafted on Eu-MOF for real-time monitoring of fresh-cut fruit freshness

Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size

Forooqi Motlaq, Vahid; Gedda, Lars; Edwards, Katarina; Doutch, James et al.

Part of Journal of Colloid and Interface Science, p. 1008-1018, 2025

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• DOI for Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size
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Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Spiegelberg, Diana; Hwang, Le-Ann; Pua, Khian Hong; Kumar, Sashwini Chandra et al.

Part of Scientific Reports, 2025

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• DOI for Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools
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The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships

Fernow, Josepine; Olliver, Marie; Couet, William; Lagrange, Sophie et al.

Part of Nature reviews. Drug discovery, p. 1-2, 2025

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• DOI for The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships
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¹⁸F-labelling of nitrogen-containing aryl boronates: anti-cancer drug melflufen as a case study

Bajerke, Kevin; Lehmann, Fredrik; Antoni, Gunnar; Szabó, Kálmán J.

Part of Organic Chemistry Frontiers, p. 6411-6417, 2024

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• DOI for ¹⁸F-labelling of nitrogen-containing aryl boronates: anti-cancer drug melflufen as a case study
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A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids

Grad, Philipp; Edwards, Katarina; Gedda, Lars; Agmo Hernández, Víctor

Part of Biochimica et Biophysica Acta - Biomembranes, 2024

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• DOI for A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids
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A film-like SERS aptasensor for sensitive detection of patulin based on GO@Au nanosheets

Xue, Shanshan; Yin, Limei; Gao, Shipeng; Zhou, Ruiyun et al.

Part of Food Chemistry, 2024

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• DOI for A film-like SERS aptasensor for sensitive detection of patulin based on GO@Au nanosheets

A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration

Wanselius, Marcus; Abrahmsen-Alami, Susanna; Hanafy, Belal I.; Mazza, Mariarosa et al.

Part of International Journal of Pharmaceutics, 2024

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• DOI for A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration
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A Simple and Cost-Effective FeCl₃-Catalyzed Functionalization of Cellulose Nanofibrils: Toward Adhesive Nanocomposite Materials for Medical Implants

Tikhomirov, Evgenii; Franconetti, Antonio; Johansson, Mathias; Sandstrom, Corine et al.

Part of ACS Applied Materials and Interfaces, p. 30385-30395, 2024

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• DOI for A Simple and Cost-Effective FeCl₃-Catalyzed Functionalization of Cellulose Nanofibrils: Toward Adhesive Nanocomposite Materials for Medical Implants

A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels

Al-Tikriti, Yassir; Hansson, Per

Part of Colloids and Surfaces A, 2024

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• DOI for A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels
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Advancements in Microfluidic Cassette-Based iMiDEV^TM Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline

Mallapura, Hemantha; Tanguy, Laurent; Mahfuz, Samin; Bylund, Lovisa et al.

Part of Pharmaceuticals, 2024

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• DOI for Advancements in Microfluidic Cassette-Based iMiDEV^TM Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline
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Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Part of ACS Pharmacology & Translational Science, p. 3228-3240, 2024

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• DOI for Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
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Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Part of Acta neuropathologica communications, 2024

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• DOI for Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
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Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids

Nilsson, Jenny M.; Balgoma, David; Pettersson, Curt; Lennernäs, Hans et al.

Part of Analytica Chimica Acta, 2024

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• DOI for Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids
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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

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• DOI for Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Part of Journal of Neurochemistry, p. 2601-2610, 2024

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• DOI for Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Are we neglecting MERS-CoV during COVID-19 pandemic: a need for refocusing on surveillance of the deadly MERS-CoV infection

Mallhi, Tauqeer Hussain; Khan, Yusra Habib; Salman, Muhammad; Butt, Muhammad Hammad

Part of Clinical Microbiology and Infection, p. 256-257, 2024

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• DOI for Are we neglecting MERS-CoV during COVID-19 pandemic: a need for refocusing on surveillance of the deadly MERS-CoV infection

Assessment of spectral ghost artifacts in echo-planar spectroscopic micro-imaging with flyback readout

Weis, Jan; Babos, Magor; Estrada, Sergio; Selvaraju, Ram Kumar

Part of Scientific Reports, 2024

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• DOI for Assessment of spectral ghost artifacts in echo-planar spectroscopic micro-imaging with flyback readout
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Atypical Complications during the Course of COVID-19: A Comprehensive Review

Mallhi, Tauqeer Hussain; Safdar, Aqsa; Butt, Muhammad Hammad; Salman, Muhammad et al.

Part of Medicina, 2024

Article, review/survey

• DOI for Atypical Complications during the Course of COVID-19: A Comprehensive Review
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Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Part of European Journal of Medicinal Chemistry Reports, 2024

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• DOI for Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
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Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization

Popov, Anton L.; Kolmanovich, Danil D.; Chukavin, Nikita N.; Zelepukin, Ivan V. et al.

Part of Molecules, 2024

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• DOI for Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
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Co-complexes on modified graphite surface for steady green hydrogen production from water at neutral pH

Toledo-Carrillo, Esteban A.; Garcia-Rodriguez, Mario; Morallon, Emilia; Cazorla-Amoros, Diego et al.

Part of Frontiers in Chemistry, 2024

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• DOI for Co-complexes on modified graphite surface for steady green hydrogen production from water at neutral pH
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Coiled-coil scallops (Chlamys farreri) peptide hydrogel with metal ionic and temperature tunable assembly

Wu, Di; Wu, Chao; Ma, Wuchao; Wang, Zhenyu et al.

Part of Food Chemistry, 2024

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• DOI for Coiled-coil scallops (Chlamys farreri) peptide hydrogel with metal ionic and temperature tunable assembly

Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Larkina, Maria; Varvashenya, Ruslan; Yuldasheva, Feruza; Plotnikov, Evgenii et al.

Part of Molecular Pharmaceutics, p. 1919-1932, 2024

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• DOI for Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Oroujeni, Maryam; Carlqvist, Matilda; Ryer, Eva; Orlova, Anna et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2024

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• DOI for Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
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Comparison of EKFC, Pakistani CKD-EPI and 2021 Race-Free CKD-EPI creatinine equations in South Asian CKD population: A study from Pakistani CKD community cohort

Safdar, Aqsa; Akram, Waqas; Khan, Mahtab Ahmad; Tahir, Danish et al.

Part of PLOS ONE, 2024

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• DOI for Comparison of EKFC, Pakistani CKD-EPI and 2021 Race-Free CKD-EPI creatinine equations in South Asian CKD population: A study from Pakistani CKD community cohort
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Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry

Cahill, Patrick L.; Moodie, Lindon W. K.; Hertzer, Cora; Pinori, Emiliano et al.

Part of Accounts of Chemical Research, p. 399-412, 2024

Article, review/survey

• DOI for Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry

Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Benediktsdottir, Andrea; Sooriyaarachchi, Sanjeewani; Cao, Sha; Ottosson, Nina E. et al.

Part of European Journal of Medicinal Chemistry, 2024

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• DOI for Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
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Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)

Niessen, Janis; Nilsson, Jenny M.; Peters, Karsten; Indulkar, Anura et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, 2024

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• DOI for Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)
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Elevated plasma level of arginine and its metabolites at labor among women with preeclampsia: A prospective cohort study

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Larsson, Anders et al.

Part of American Journal of Hypertension, p. 184-191, 2024

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• DOI for Elevated plasma level of arginine and its metabolites at labor among women with preeclampsia: A prospective cohort study
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Elevated Plasma Levels of Arginines During Labor Among Women with Spontaneous Preterm Birth: A Prospective Cohort Study

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Ubhayasekera, Kumari et al.

Part of American Journal of Reproductive Immunology, 2024

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• DOI for Elevated Plasma Levels of Arginines During Labor Among Women with Spontaneous Preterm Birth: A Prospective Cohort Study
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Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space

Rodler, Agnes; Samanta, Ayan; Goh, Wen-Jun; Hilborn, Jöns et al.

Part of European Polymer Journal, 2024

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• DOI for Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space
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Enhanced Risk Assessment of Transformation Products through Chemical Similarity Analysis

Löffler, Paul; Lai, Adelene; Henschel, Henning; Spilsbury, Francis et al.

Part of ACS - ES & T Water, p. 1949-1951, 2024

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• DOI for Enhanced Risk Assessment of Transformation Products through Chemical Similarity Analysis
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Evaluation of [¹¹C]UCB-A positron emission tomography in human brains

Xiong, Mengfei; Lubberink, Mark; Appel, Lieuwe; Fang, Xiaotian Tsong et al.

Part of EJNMMI Research, 2024

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• DOI for Evaluation of [¹¹C]UCB-A positron emission tomography in human brains
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Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile

Liu, Yongsheng; Oroujeni, Maryam; Liao, Yunqi; Vorobyeva, Anzhelika et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 4038-4048, 2024

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• DOI for Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
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Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

Nagy, Abel; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Landmark, Fredrika et al.

Part of ACS Omega, p. 36122-36133, 2024

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• DOI for Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
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Evaluation of clinical and laboratory characteristics of dengue viral infection and risk factors of dengue hemorrhagic fever: a multi-center retrospective analysis

Riaz, Muhammad; Harun, Sabriah Noor Binti; Mallhi, Tauqeer Hussain; Khan, Yusra Habib et al.

Part of BMC Infectious Diseases, 2024

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• DOI for Evaluation of clinical and laboratory characteristics of dengue viral infection and risk factors of dengue hemorrhagic fever: a multi-center retrospective analysis
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Formulation and evaluation of miconazole lipogel for enhanced drug permeation

Ahsan, Ali; Waqar, Muhammad Ahsan; Riaz, Tehseen; Qureshi, Aimon et al.

Part of Pakistan Journal of Pharmaceutical Sciences, p. 95-105, 2024

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FRAP analysis of peptide diffusion in extracellular matrix mimetic hydrogels as an in vitro model for subcutaneous injection

Parlow, Julia; Rodler, Agnes; Gråsjö, Johan; Sjögren, Helen et al.

Part of International Journal of Pharmaceutics, 2024

Article in journal

• DOI for FRAP analysis of peptide diffusion in extracellular matrix mimetic hydrogels as an in vitro model for subcutaneous injection

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

Obeid, Karim; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Mattsson, Adam et al.

Part of Pharmaceutics, 2024

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• DOI for GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
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Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.

Zhang, Jie; Bodenko, Vitalina; Larkina, Maria; Bezverkhniaia, Ekaterina et al.

Part of Journal of Controlled Release, p. 468-478, 2024

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• DOI for Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
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Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging

Lodén, Henrik; Schembri, Luke S; Nilsson, Anna; Kaya, Ibrahim et al.

Part of Chemical Communications, p. 9238-9241, 2024

Article in journal

• DOI for Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging

Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain

Vallianatou, Theodosia; de Souza Anselmo, Carina; Tsiara, Ioanna; Bechet, Nicholas B. et al.

Part of ACS Chemical Neuroscience, p. 1335-1341, 2024

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• DOI for Identification of New Ketamine Metabolites and Their Detailed Distribution in the Mammalian Brain
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