Våra aktuella publiceringar

Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes

Söderström, Marcus; Olaniran Håkansson, Esther; Odell, Luke R.

Ingår i Chemical Communications, s. 145-148, 2025

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• DOI för Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes
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DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Ingår i Scientific Reports, 2025

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• DOI för DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths

Aro, Olli-Pekka; Casula, Victor; Hänninen, Nina E.; Karjalainen, Jouni et al.

Ingår i Heliyon, 2025

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• DOI för Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths

Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?

Kanellopoulos, Panagiotis; Yu, Quanyi; Abouzayed, Abouzayed; Bezverkhniaia, Ekaterina et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI för Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [^99mTc]Tc-labeled counterparts be used to estimate dosimetry?
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First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT

Bjareback, Annie; Jonmarker, Olof; Tzortzakakis, Antonios; Jussing, Emma et al.

Ingår i EJNMMI Research, 2025

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• DOI för First-in-human experience with GRPR antagonist [⁶⁸Ga]Ga-NOTA-PEG₂-RM26 in prostate and breast cancer patients using PET/CT
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Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)

Miszczak, Rebecca; Slazak, Blazej; Sychta, Klaudia; Göransson, Ulf et al.

Ingår i Plants, 2025

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• DOI för Interpopulational Variation in Cyclotide Production in Heavy-Metal-Treated Pseudometallophyte (Viola tricolor L.)
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025

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• DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Pharmacokinetics and Alterations in Glucose and Insulin Levels After a Single Dose of Canagliflozin in Healthy Icelandic Horses

Michanek, Peter; Bröjer, Johan; Lilliehöök, Inger; Fjordbakk, Cathrine T et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 41-49, 2025

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• DOI för Pharmacokinetics and Alterations in Glucose and Insulin Levels After a Single Dose of Canagliflozin in Healthy Icelandic Horses
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Ingår i Intensive Care Medicine Experimental, 2025

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• DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Smartphone-assisted fluorescent film based on the Flu grafted on Eu-MOF for real-time monitoring of fresh-cut fruit freshness

Zhang, Zhepeng; Gao, Mingjie; Zhang, Liang; Li, Jiangbo et al.

Ingår i Biosensors & bioelectronics, 2025

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• DOI för Smartphone-assisted fluorescent film based on the Flu grafted on Eu-MOF for real-time monitoring of fresh-cut fruit freshness

Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size

Forooqi Motlaq, Vahid; Gedda, Lars; Edwards, Katarina; Doutch, James et al.

Ingår i Journal of Colloid and Interface Science, s. 1008-1018, 2025

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• DOI för Spontaneous formation of small and ultrasmall unilamellar vesicles in mixtures of drug surfactant and phospholipid: Effect of chemical structure of phospholipid tails on vesicle size
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Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

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• DOI för Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [¹⁸F]MeTz-PEG2-RM26 for positron emission tomography
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Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools

Spiegelberg, Diana; Hwang, Le-Ann; Pua, Khian Hong; Kumar, Sashwini Chandra et al.

Ingår i Scientific Reports, 2025

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• DOI för Targeting mutant p53: Evaluation of novel anti-p53^R175H monoclonal antibodies as diagnostic tools
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The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships

Fernow, Josepine; Olliver, Marie; Couet, William; Lagrange, Sophie et al.

Ingår i Nature reviews. Drug discovery, s. 1-2, 2025

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• DOI för The AMR Accelerator: from individual organizations to efficient antibiotic development partnerships
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¹⁸F-labelling of nitrogen-containing aryl boronates: anti-cancer drug melflufen as a case study

Bajerke, Kevin; Lehmann, Fredrik; Antoni, Gunnar; Szabó, Kálmán J.

Ingår i Organic Chemistry Frontiers, s. 6411-6417, 2024

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• DOI för ¹⁸F-labelling of nitrogen-containing aryl boronates: anti-cancer drug melflufen as a case study
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A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids

Grad, Philipp; Edwards, Katarina; Gedda, Lars; Agmo Hernández, Víctor

Ingår i Biochimica et Biophysica Acta - Biomembranes, 2024

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• DOI för A closer look at calcium-induced interactions between phosphatidylserine-(PS) doped liposomes and the structural effects caused by inclusion of gangliosides or polyethylene glycol- (PEG) modified lipids
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A film-like SERS aptasensor for sensitive detection of patulin based on GO@Au nanosheets

Xue, Shanshan; Yin, Limei; Gao, Shipeng; Zhou, Ruiyun et al.

Ingår i Food Chemistry, 2024

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• DOI för A film-like SERS aptasensor for sensitive detection of patulin based on GO@Au nanosheets

A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration

Wanselius, Marcus; Abrahmsen-Alami, Susanna; Hanafy, Belal I.; Mazza, Mariarosa et al.

Ingår i International Journal of Pharmaceutics, 2024

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• DOI för A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration
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A Simple and Cost-Effective FeCl₃-Catalyzed Functionalization of Cellulose Nanofibrils: Toward Adhesive Nanocomposite Materials for Medical Implants

Tikhomirov, Evgenii; Franconetti, Antonio; Johansson, Mathias; Sandstrom, Corine et al.

Ingår i ACS Applied Materials and Interfaces, s. 30385-30395, 2024

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• DOI för A Simple and Cost-Effective FeCl₃-Catalyzed Functionalization of Cellulose Nanofibrils: Toward Adhesive Nanocomposite Materials for Medical Implants

A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels

Al-Tikriti, Yassir; Hansson, Per

Ingår i Colloids and Surfaces A, 2024

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• DOI för A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels
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Advancements in Microfluidic Cassette-Based iMiDEV^TM Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline

Mallapura, Hemantha; Tanguy, Laurent; Mahfuz, Samin; Bylund, Lovisa et al.

Ingår i Pharmaceuticals, 2024

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• DOI för Advancements in Microfluidic Cassette-Based iMiDEV^TM Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline
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Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

Zhang, Jie; Rinne, Sara S.; Yin, Wen; Leitao, Charles Dahlsson et al.

Ingår i ACS Pharmacology & Translational Science, s. 3228-3240, 2024

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• DOI för Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts
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Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Ingår i Acta neuropathologica communications, 2024

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• DOI för Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
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Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids

Nilsson, Jenny M.; Balgoma, David; Pettersson, Curt; Lennernäs, Hans et al.

Ingår i Analytica Chimica Acta, 2024

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• DOI för Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids
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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

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• DOI för Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

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• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Are we neglecting MERS-CoV during COVID-19 pandemic: a need for refocusing on surveillance of the deadly MERS-CoV infection

Mallhi, Tauqeer Hussain; Khan, Yusra Habib; Salman, Muhammad; Butt, Muhammad Hammad

Ingår i Clinical Microbiology and Infection, s. 256-257, 2024

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• DOI för Are we neglecting MERS-CoV during COVID-19 pandemic: a need for refocusing on surveillance of the deadly MERS-CoV infection

Assessment of spectral ghost artifacts in echo-planar spectroscopic micro-imaging with flyback readout

Weis, Jan; Babos, Magor; Estrada, Sergio; Selvaraju, Ram Kumar

Ingår i Scientific Reports, 2024

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• DOI för Assessment of spectral ghost artifacts in echo-planar spectroscopic micro-imaging with flyback readout
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Atypical Complications during the Course of COVID-19: A Comprehensive Review

Mallhi, Tauqeer Hussain; Safdar, Aqsa; Butt, Muhammad Hammad; Salman, Muhammad et al.

Ingår i Medicina, 2024

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• DOI för Atypical Complications during the Course of COVID-19: A Comprehensive Review
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Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Ingår i European Journal of Medicinal Chemistry Reports, 2024

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• DOI för Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
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Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization

Popov, Anton L.; Kolmanovich, Danil D.; Chukavin, Nikita N.; Zelepukin, Ivan V. et al.

Ingår i Molecules, 2024

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• DOI för Boron Nanoparticle-Enhanced Proton Therapy: Molecular Mechanisms of Tumor Cell Sensitization
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Co-complexes on modified graphite surface for steady green hydrogen production from water at neutral pH

Toledo-Carrillo, Esteban A.; Garcia-Rodriguez, Mario; Morallon, Emilia; Cazorla-Amoros, Diego et al.

Ingår i Frontiers in Chemistry, 2024

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• DOI för Co-complexes on modified graphite surface for steady green hydrogen production from water at neutral pH
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Coiled-coil scallops (Chlamys farreri) peptide hydrogel with metal ionic and temperature tunable assembly

Wu, Di; Wu, Chao; Ma, Wuchao; Wang, Zhenyu et al.

Ingår i Food Chemistry, 2024

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• DOI för Coiled-coil scallops (Chlamys farreri) peptide hydrogel with metal ionic and temperature tunable assembly

Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Larkina, Maria; Varvashenya, Ruslan; Yuldasheva, Feruza; Plotnikov, Evgenii et al.

Ingår i Molecular Pharmaceutics, s. 1919-1932, 2024

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• DOI för Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the ^99mTc-Based Imaging of HER2-Expressing Malignant Tumors

Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation

Oroujeni, Maryam; Carlqvist, Matilda; Ryer, Eva; Orlova, Anna et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2024

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• DOI för Comparison of approaches for increasing affinity of affibody molecules for imaging of B7-H3: dimerization and affinity maturation
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Comparison of EKFC, Pakistani CKD-EPI and 2021 Race-Free CKD-EPI creatinine equations in South Asian CKD population: A study from Pakistani CKD community cohort

Safdar, Aqsa; Akram, Waqas; Khan, Mahtab Ahmad; Tahir, Danish et al.

Ingår i PLOS ONE, 2024

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• DOI för Comparison of EKFC, Pakistani CKD-EPI and 2021 Race-Free CKD-EPI creatinine equations in South Asian CKD population: A study from Pakistani CKD community cohort
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Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry

Cahill, Patrick L.; Moodie, Lindon W. K.; Hertzer, Cora; Pinori, Emiliano et al.

Ingår i Accounts of Chemical Research, s. 399-412, 2024

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• DOI för Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry

Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Benediktsdottir, Andrea; Sooriyaarachchi, Sanjeewani; Cao, Sha; Ottosson, Nina E. et al.

Ingår i European Journal of Medicinal Chemistry, 2024

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• DOI för Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
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Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)

Niessen, Janis; Nilsson, Jenny M.; Peters, Karsten; Indulkar, Anura et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2024

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• DOI för Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)
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Elevated plasma level of arginine and its metabolites at labor among women with preeclampsia: A prospective cohort study

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Larsson, Anders et al.

Ingår i American Journal of Hypertension, s. 184-191, 2024

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• DOI för Elevated plasma level of arginine and its metabolites at labor among women with preeclampsia: A prospective cohort study
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Elevated Plasma Levels of Arginines During Labor Among Women with Spontaneous Preterm Birth: A Prospective Cohort Study

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Ubhayasekera, Kumari et al.

Ingår i American Journal of Reproductive Immunology, 2024

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• DOI för Elevated Plasma Levels of Arginines During Labor Among Women with Spontaneous Preterm Birth: A Prospective Cohort Study
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Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space

Rodler, Agnes; Samanta, Ayan; Goh, Wen-Jun; Hilborn, Jöns et al.

Ingår i European Polymer Journal, 2024

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• DOI för Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space
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Enhanced Risk Assessment of Transformation Products through Chemical Similarity Analysis

Löffler, Paul; Lai, Adelene; Henschel, Henning; Spilsbury, Francis et al.

Ingår i ACS - ES & T Water, s. 1949-1951, 2024

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• DOI för Enhanced Risk Assessment of Transformation Products through Chemical Similarity Analysis
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Evaluation of [¹¹C]UCB-A positron emission tomography in human brains

Xiong, Mengfei; Lubberink, Mark; Appel, Lieuwe; Fang, Xiaotian Tsong et al.

Ingår i EJNMMI Research, 2024

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• DOI för Evaluation of [¹¹C]UCB-A positron emission tomography in human brains
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Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile

Liu, Yongsheng; Oroujeni, Maryam; Liao, Yunqi; Vorobyeva, Anzhelika et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4038-4048, 2024

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• DOI för Evaluation of a novel ¹⁷⁷Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
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Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

Nagy, Abel; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Landmark, Fredrika et al.

Ingår i ACS Omega, s. 36122-36133, 2024

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• DOI för Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
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Evaluation of clinical and laboratory characteristics of dengue viral infection and risk factors of dengue hemorrhagic fever: a multi-center retrospective analysis

Riaz, Muhammad; Harun, Sabriah Noor Binti; Mallhi, Tauqeer Hussain; Khan, Yusra Habib et al.

Ingår i BMC Infectious Diseases, 2024

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• DOI för Evaluation of clinical and laboratory characteristics of dengue viral infection and risk factors of dengue hemorrhagic fever: a multi-center retrospective analysis
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Formulation and evaluation of miconazole lipogel for enhanced drug permeation

Ahsan, Ali; Waqar, Muhammad Ahsan; Riaz, Tehseen; Qureshi, Aimon et al.

Ingår i Pakistan Journal of Pharmaceutical Sciences, s. 95-105, 2024

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FRAP analysis of peptide diffusion in extracellular matrix mimetic hydrogels as an in vitro model for subcutaneous injection

Parlow, Julia; Rodler, Agnes; Gråsjö, Johan; Sjögren, Helen et al.

Ingår i International Journal of Pharmaceutics, 2024

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• DOI för FRAP analysis of peptide diffusion in extracellular matrix mimetic hydrogels as an in vitro model for subcutaneous injection

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

Obeid, Karim; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Mattsson, Adam et al.

Ingår i Pharmaceutics, 2024

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• DOI för GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics
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