Våra aktuella publiceringar

A novel ¹⁸F-labelled tetrazine ester prosthetic group for improved radiolabelling and in vivo stability of proteins and peptides

Lechi, Francesco; Odell, Luke R.; Wegrzyniak, Olivia; Balestri, Lorenzo et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2026

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• DOI för A novel ¹⁸F-labelled tetrazine ester prosthetic group for improved radiolabelling and in vivo stability of proteins and peptides
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A Separation Buffers Platform Set to Facilitate CZE Charge Heterogeneity Method Development for Monoclonal Antibodies

Baxter, Joanne; Waltham, Kevin; Fitton, Lori; Sänger-van de Griend, Cari E.

Ingår i ELECTROPHORESIS, 2026

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• DOI för A Separation Buffers Platform Set to Facilitate CZE Charge Heterogeneity Method Development for Monoclonal Antibodies

Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses

Ekstrand, Carl; Michanek, Peter; Hernlund, Elin; Gehring, Ronette et al.

Ingår i Journal of Veterinary Pharmacology and Therapeutics, s. 22-32, 2026

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• DOI för Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses
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Diffusion of Affibody molecules in extracellular matrix mimetic hydrogels and the effect of albumin binding

Parlow, Julia; Sandegren, Anna; Güler, Rezan; Karlberg, Ida et al.

Ingår i International Journal of Biological Macromolecules, 2026

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• DOI för Diffusion of Affibody molecules in extracellular matrix mimetic hydrogels and the effect of albumin binding
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Efficient ⁶⁸Ga Labeling of a B7-H3-Targeting Affibody Molecule via Acyclic Tris(hydroxypyridinone) Chelator: Effects on Biodistribution in a Preclinical Model

Tolmachev, Vladimir; Herlina, Amelinda Janice; Papalanis, Eleftherios; Bezverkhniaia, Ekaterina A. et al.

Ingår i International Journal of Molecular Sciences, 2026

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• DOI för Efficient ⁶⁸Ga Labeling of a B7-H3-Targeting Affibody Molecule via Acyclic Tris(hydroxypyridinone) Chelator: Effects on Biodistribution in a Preclinical Model
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Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging

Obeid, Karim; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir M.; Orlova, Anna et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2026

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• DOI för Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging
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Heterocyclic scaffold-fused dimethoxy-dibenzocyclooctynes for photoactivatable click chemistry

Larsson, N. Alfred; Jo, Taegeun; Bremberg, Ulf; Crespi, Stefano et al.

Ingår i Organic and biomolecular chemistry, s. 120-126, 2026

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• DOI för Heterocyclic scaffold-fused dimethoxy-dibenzocyclooctynes for photoactivatable click chemistry
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Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1.

Krompholz, Marlon; Blanc, Timothy; Lu, Huixin; Christensen, Patricia et al.

Ingår i Electrophoresis, 2026

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• DOI för Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1.

Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history

Rossi, Maria Eleonora; Keating, Joseph N.; Kenny, Nathan J.; Giacomelli, Mattia et al.

Ingår i Science Advances, 2026

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• DOI för Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history
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Late-stage defluorinative functionalization: synthesis of thio-amides and heterocycles from trifluoromethylarenes

Söderström, Marcus; Olaniran Håkansson, Esther; Odell, Luke R.

Ingår i Organic Chemistry Frontiers, s. 1275-1280, 2026

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• DOI för Late-stage defluorinative functionalization: synthesis of thio-amides and heterocycles from trifluoromethylarenes
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Low-dose testosterone administration and oestrogen synthase availability in the female brain: A pilot study

Dubol, Manon; Jonasson, My; Takahashi, Kayo; Wikström, Johan et al.

Ingår i Journal of neuroendocrinology, 2026

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• DOI för Low-dose testosterone administration and oestrogen synthase availability in the female brain: A pilot study
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Novel approaches for PET imaging of endometriosis

Zhang, Hongchao; Eriksson, Olof; Olovsson, Matts; Wilson, Viola et al.

Ingår i Nuclear Medicine and Biology, 2026

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• DOI för Novel approaches for PET imaging of endometriosis
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Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange

Laurén, Ida; Kostakis, Alexandros; Lord, Martin; Björklund, Elvira et al.

Ingår i International Journal of Biological Macromolecules, 2026

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• DOI för Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange
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Preclinical Evaluation of a ¹⁷⁷Lu-Labeled Gastrin-Releasing Peptide Receptor Antagonist and Prostate Cancer Treatment with Monotherapy and in Combination with Everolimus

Kumar, Naveen; Bilinska, Adrianna; Menéndez, Elena; Läppchen, Tilman et al.

Ingår i ACS Pharmacology & Translational Science, s. 59-68, 2026

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• DOI för Preclinical Evaluation of a ¹⁷⁷Lu-Labeled Gastrin-Releasing Peptide Receptor Antagonist and Prostate Cancer Treatment with Monotherapy and in Combination with Everolimus
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Preclinical evaluation of an antibody-based companion diagnostic for CD44v6 expressing cancer

Oroujeni, Maryam; Selvaraju, Ram Kumar; Persson, Helena; Dahllund, Leif et al.

Ingår i Nuclear medicine communications, s. 401-410, 2026

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• DOI för Preclinical evaluation of an antibody-based companion diagnostic for CD44v6 expressing cancer
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Preclinical Validation of [¹⁷⁷Lu]Lu-AKIR001, a CD44v6-Targeted Radiotherapeutic Entering First-in-Human Trials

Mortensen, Anja C. L.; Mohajershojai, Tabassom; Gustafsson, Amanda; Berglund, Hanna et al.

Ingår i Journal of Nuclear Medicine, s. 269-275, 2026

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• DOI för Preclinical Validation of [¹⁷⁷Lu]Lu-AKIR001, a CD44v6-Targeted Radiotherapeutic Entering First-in-Human Trials
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Profiling of 5-hydroxymethylcytosine in blood reveals preferential enrichment at exon-intron junctions and predictive value for Parkinson's disease

Antczak, Philipp; Brandt, Peter; Radosavljevic, Lav; Svenningsson, Per et al.

Ingår i npj Parkinson's Disease, 2026

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• DOI för Profiling of 5-hydroxymethylcytosine in blood reveals preferential enrichment at exon-intron junctions and predictive value for Parkinson's disease
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Revealing the Morphology of Small Multilamellar Lipid Nanoparticles (SMLPs) made by In-Vial Homogenization

Akcesme, Sevda; Schmager, Stefanie; Al-Tikriti, Yassir; Gedda, Lars et al.

Ingår i European Journal of Pharmaceutical Sciences, 2026

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• DOI för Revealing the Morphology of Small Multilamellar Lipid Nanoparticles (SMLPs) made by In-Vial Homogenization
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Structural determination of self-assembled aggregates formed by a therapeutic cyclical peptide and an ionic surfactant in aqueous solution

Brunzell, Ellen; Kim Högström, Yumi; López Hernández, Marcos; Skov Pedersen, Jan et al.

Ingår i Journal of Colloid and Interface Science, 2026

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• DOI för Structural determination of self-assembled aggregates formed by a therapeutic cyclical peptide and an ionic surfactant in aqueous solution
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Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH

Haglöf, Jakob; Regnell, Julia; Sänger-van de Griend, Cari

Ingår i Analytica Chimica Acta, 2026

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• DOI för Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH
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Toward generalizable predictive models for DNA-encoded libraries.

Poongavanam, Vasanthanathan; Turunen, S Pauliina; Sandberg, Kristian; Yngve, Ulrika et al.

Ingår i Drug Discovery Today, s. 104629, 2026

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• DOI för Toward generalizable predictive models for DNA-encoded libraries.

Tumour accumulation of anti-carcinoembryonic antigen affibody-albumin-binding domain fusion depends on domains' order

Papalanis, Eleftherios; Li, Ruonan; Oroujeni, Maryam; Zhang, Jie et al.

Ingår i International Journal of Biological Macromolecules, 2026

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• DOI för Tumour accumulation of anti-carcinoembryonic antigen affibody-albumin-binding domain fusion depends on domains' order
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A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats

Niessen, Janis; Arendt, Nathalie; Sjöblom, Markus; Dubbelboer, Ilse R. et al.

Ingår i European journal of pharmaceutics and biopharmaceutics, 2025

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• DOI för A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats
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A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary

Lindman, Jens; Puthiyaparambath, Sharathna; Gising, Johan; Odell, Luke R. et al.

Ingår i Synlett, s. 2009-2013, 2025

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• DOI för A Diastereoselective Mizoroki-Heck Reaction for Synthesis of Spirooxindole-Based Nonnatural Amino Acids Using a Boc-Protected Amine Chiral Auxiliary
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A Multicomponent aza-Prins Strategy for the Diastereoselective Synthesis of Piperidine-Fused Dihydroquinazolinones

Dybeck, Lovisa; Baudoin, Morgane; Odell, Luke R.

Ingår i European Journal of Organic Chemistry, 2025

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• DOI för A Multicomponent aza-Prins Strategy for the Diastereoselective Synthesis of Piperidine-Fused Dihydroquinazolinones
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A Phase I/IIa Clinical Trial to Evaluate Safety and Adrenal Uptake of Para-Chloro-2-[¹⁸F]Fluoroethyletomidate in Healthy Volunteers and Patients with Primary Aldosteronism

Gillett, Daniel; Senanayake, Russell; MacFarlane, James; Bashari, Waiel et al.

Ingår i Journal of Nuclear Medicine, s. 434-440, 2025

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• DOI för A Phase I/IIa Clinical Trial to Evaluate Safety and Adrenal Uptake of Para-Chloro-2-[¹⁸F]Fluoroethyletomidate in Healthy Volunteers and Patients with Primary Aldosteronism

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

Tricht, Ewoud van; Sänger-van de Griend, Cari

Ingår i Electrophoresis, s. 933-953, 2025

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• DOI för A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development
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A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression

Olaniran Håkansson, Esther; Zelepukin, Ivan V.; Obeid, Karim; Bitzios, Athanasios et al.

Ingår i EJNMMI Research, 2025

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• DOI för A preclinical study on the influence of linkers in [⁶⁸Ga]Ga-NOTA-X-RM26 radiotracers for PET imaging of GRPR expression
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A universal language for finding mass spectrometry data patterns

Damiani, Tito; Jarmusch, Alan K.; Aron, Allegra T.; Petras, Daniel et al.

Ingår i Nature Methods, 2025

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• DOI för A universal language for finding mass spectrometry data patterns
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Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents

Rinne, Sara S.; Yin, Wen; Li, Ruonan; Ding, Haozhong et al.

Ingår i ACS Pharmacology & Translational Science, s. 3872-3885, 2025

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• DOI för Affibody-Derived Drug Conjugates Targeting The Epidermal Growth Factor Receptor Are Potent And Specific Cytotoxic Agents
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Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure-Activity Relationship

Safratova, Marcela; Chen, Yu-Li; Hostalkova, Anna; Chlebek, Jakub et al.

Ingår i Influenza and Other Respiratory Viruses, 2025

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• DOI för Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure-Activity Relationship
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Benzylhydroxamic Acids as IRAP Inhibitors: Sulfonamide Variations

Beveridge, Julia; Söderström, Marcus; Balestri, Lorenzo; Prieto-Díaz, Rubén et al.

Ingår i Synlett, s. 2666-2670, 2025

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• DOI för Benzylhydroxamic Acids as IRAP Inhibitors: Sulfonamide Variations
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Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease

Kaya, Ibrahim; Vallianatou, Theodosia; Nilsson, Anna; Bjärterot, Patrik et al.

Ingår i npj Parkinson's Disease, 2025

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• DOI för Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease
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Canagliflozin: Pharmacokinetics, tolerability and glucose/insulin effects of supratherapeutic doses in healthy horses

Michanek, Peter; Bröjer, Johan; Lilliehöök, Inger; Fjordbakk, Cathrine et al.

Ingår i The Veterinary Journal, 2025

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• DOI för Canagliflozin: Pharmacokinetics, tolerability and glucose/insulin effects of supratherapeutic doses in healthy horses
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Carboxylate and coordination influence on the formation of an active RuV Oxo species

El-Abid, Jamal; Dorst, Kevin M.; Inge, Andrew K.; Verho, Oscar et al.

Ingår i Scientific Reports, 2025

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• DOI för Carboxylate and coordination influence on the formation of an active RuV Oxo species
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Chemical characterization of C₃₁ sterols from sponges and Neoproterozoic fossil sterane counterparts

Shawar, Lubna; Love, Gordon D.; Uveges, Benjamin T.; Zumberge, J. Alex et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2025

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• DOI för Chemical characterization of C₃₁ sterols from sponges and Neoproterozoic fossil sterane counterparts
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Cobaltaelectro-catalyzed C–H acyloxylation of aromatic and vinylic amide derivatives at room temperature

Sitdikov, Ruzal; Nikolaienko, Pavlo; Meyer, Luca; Verho, Oscar

Ingår i Chemical Communications, s. 16946-16949, 2025

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• DOI för Cobaltaelectro-catalyzed C–H acyloxylation of aromatic and vinylic amide derivatives at room temperature
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Connectivity and Adaptation Patterns of the Deep-Sea Ground-Forming Sponge Geodia hentscheli Across Its Entire Distribution

Taboada, Sergi; Diez-Vives, Cristina; Turon, Marta; Belen Arias, Maria et al.

Ingår i Molecular biology and evolution, 2025

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• DOI för Connectivity and Adaptation Patterns of the Deep-Sea Ground-Forming Sponge Geodia hentscheli Across Its Entire Distribution
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Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides

Valli, Dylan; Ooi, Saik Ann; Kaya, Ibrahim; Thomassen, Asger Berg et al.

Ingår i Biochemistry, s. 2583-2595, 2025

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• DOI för Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides
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Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes

Söderström, Marcus; Olaniran Håkansson, Esther; Odell, Luke R.

Ingår i Chemical Communications, s. 145-148, 2025

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• DOI för Defluorinative thio-functionalization: direct synthesis of methyl-dithioesters from trifluoromethylarenes
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Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

Vallianatou, Theodosia; Ilic Balestri, Lorenzo Jacopo; Nilsson, Anna; Zhang, Xiaoqun et al.

Ingår i Chemistry-Methods, 2025

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• DOI för Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging
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Designed Ankyrin Repeat Protein-Mediated Peptide Nucleic Acid-Based Pretargeting: A Proof-of-Principle Study

Oroujeni, Maryam; Westerlund, Kristina; Papalanis, Eleftherios; van Deventer, Alexander et al.

Ingår i Journal of Nuclear Medicine, s. 1105-1111, 2025

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• DOI för Designed Ankyrin Repeat Protein-Mediated Peptide Nucleic Acid-Based Pretargeting: A Proof-of-Principle Study

Development and in vitro evaluation of lipodisks optimized for co-delivery of chemotherapeutic drugs and membranolytic anticancer peptides

Silva, Luis; Ali, Sajid; Gedda, Lars; Agmo Hernández, Víctor et al.

Ingår i Journal of Colloid and Interface Science, 2025

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• DOI för Development and in vitro evaluation of lipodisks optimized for co-delivery of chemotherapeutic drugs and membranolytic anticancer peptides
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Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Haglöf, Jakob; Nilsson, Jenny M.; Ludvigsson, Jufang Wu

Ingår i Journal of Separation Science, 2025

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• DOI för Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
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DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells

Cheung, Pierre; Persson, Jonas; Zhang, Bo; Vasylovska, Svitlana et al.

Ingår i Scientific Reports, 2025

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• DOI för DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells
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Diffusion of macromolecules in extracellular matrix mimetic hydrogels: effect of size and charge

Parlow, Julia; Pet, Eva; Smirnova, Anna; Mojumdar, Enamul et al.

Ingår i European Journal of Pharmaceutical Sciences, 2025

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• DOI för Diffusion of macromolecules in extracellular matrix mimetic hydrogels: effect of size and charge
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Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance

Hornyak, Marta; Kula-Maximenko, Monika; Miszalski, Zbigniew; Nilsson, Anna et al.

Ingår i Scientific Reports, 2025

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• DOI för Distribution of photosensitive fagopyrin in buckwheat flowers and its potential biological relevance
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Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts

Mortensen, Anja; Berglund, Hanna; Jha, Preeti; Stenman, Adam et al.

Ingår i Molecular Cancer Therapeutics, s. 753-762, 2025

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• DOI för Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
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Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths

Aro, Olli-Pekka; Casula, Victor; Hänninen, Nina E.; Karjalainen, Jouni et al.

Ingår i Heliyon, 2025

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• DOI för Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths
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Emergence of pseudoresonance in high-intensity resonant inelastic x-ray scattering

Son, Sang-Kil; Baumann, Thomas M.; Pedersen, Jacob; Budewig, Laura et al.

Ingår i Physical Review A: covering atomic, molecular, and optical physics and quantum information, 2025

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• DOI för Emergence of pseudoresonance in high-intensity resonant inelastic x-ray scattering
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