Pharmaceutical Physics

Illustration from https://doi.org/10.1016/j.ijpharm.2018.12.064

Illustration from https://doi.org/10.1016/j.ijpharm.2018.12.064

Research in Pharmaceutical Physics at Uppsala University

Description

In the research area of Pharmaceutical Physics, the design, manufacturing and performance of drug-delivery systems are studied. Our ambition is to conduct methodological and basic mechanistic research that contributes to the development of effective, patient oriented and more cost-effective medicines.

We develop, firstly, new and improved drug-delivery solutions and, secondly, tools that enable a more effective development and manufacturing of drug products. The core expertise of the group is powder science and technology which is a scientific discipline with applications to different type of products, including pharmaceuticals. An important and common research question is how critical properties of particles and particle systems can be assessed, controlled and predicted. The main applications of the research are formulation of medicines for peroral and pulmonary administration.

The research group is led by professor Göran Frenning. Other senior researchers in the group are emeritus professor Göran Alderborn and lecturers Erik Björk, Josefina Nordström and Ann-Sofie Persson. The research group is involved in the competence centre SweDeliver.

Formulation of solid oral dosage forms

Determing compression parameters to characterize particle properties and predict tablet-forming abilities.

Formulation of inhaled medicines

Studies of physical and formulation properties of carrier-based formulations, so called adhesive mixtures.

Modelling and simulation

Developing non local contact models and simulation methods for efficient and accurate particle-scale modelling of powders.

Contact the research group in Pharmaceutical Physics

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