Pharmacognosy

Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation: Isolation of bromopyrrole alkaloids from Stylissa massa

Kosgahakumbura, Lakmini; Gamage, Jayani; Robertson, Luke; Muhammad, Taj et al.

Part of PLOS ONE, 2024

• DOI for Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation: Isolation of bromopyrrole alkaloids from Stylissa massa
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Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads

Muhammad, Taj; Strömstedt, Adam A.; Gunasekera, Sunithi; Göransson, Ulf

Part of Biomedicines, 2023

• DOI for Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads
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Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from Geophila repens

Rajendran, Sanjeevan; Slazak, Blazej; Mohotti, Supun; Muhammad, Taj et al.

Part of Journal of Natural Products, p. 52-65, 2023

• DOI for Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from Geophila repens
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Antibacterial eremophilane sesquiterpenoids from Xylaria feejeensis, an endophytic fungi of the medicinal plant Geophila repens

Rajendran, Sanjeevan; Robertson, Luke P.; Kosgahakumbura, Lakmini; Fernando, Chathurika et al.

Part of Fitoterapia, 2023

• DOI for Antibacterial eremophilane sesquiterpenoids from Xylaria feejeensis, an endophytic fungi of the medicinal plant Geophila repens
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On the structures of the penduflorines from Tabernaemontana penduliflora

Beniddir, Mehdi A.; Göransson, Ulf; Robertson, Luke P.

Part of Fitoterapia, 2023

• DOI for On the structures of the penduflorines from Tabernaemontana penduliflora
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Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro

Melander, Erik; Eriksson, Camilla; Wellens, Sara; Hosseini, Kimia et al.

Part of Pharmaceutics, 2023

• DOI for Differential Blood-Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro
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KR-12 derivatives endow nanocellulose with antibacterial and anti-inflammatory properties: Role of conjugation chemistry

Blasi Romero, Anna; Ångström, Molly; Franconetti, Antonio; Muhammad, Taj et al.

Part of ACS Applied Materials and Interfaces, p. 24186-24196, 2023

• DOI for KR-12 derivatives endow nanocellulose with antibacterial and anti-inflammatory properties: Role of conjugation chemistry

Anti-inflammatory and Antiphytopathogenic Fungal Activity of 2,3-seco-Tirucallane Triterpenoids Meliadubins A and B from Melia dubia Cav. Barks with ChemGPS-NP and In Silico Prediction

Trung, Hieu Tran; Purnomo, Kartiko Arif; Yu, Szu-Yin; Yang, Zih-Jie et al.

Part of ACS Omega, p. 37116-37127, 2023

• DOI for Anti-inflammatory and Antiphytopathogenic Fungal Activity of 2,3-seco-Tirucallane Triterpenoids Meliadubins A and B from Melia dubia Cav. Barks with ChemGPS-NP and In Silico Prediction
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A Synthetic Cyclized Antimicrobial Peptide with Potent Effects against Drug-Resistant Skin Pathogens

Kerr White, John; Mohanty, Soumitra; Muhammad, Taj; de Arriba Sanchez de la Campa, Magdalena et al.

Part of ACS - Infectious Diseases, p. 1056-1063, 2023

• DOI for A Synthetic Cyclized Antimicrobial Peptide with Potent Effects against Drug-Resistant Skin Pathogens
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Exploring the limits of cyanobactin macrocyclase PatGmac: Cyclization of PawS-derived peptide sunflower trypsin inhibitor-1 and cyclotide kalata B1

Muhammad, Taj; Houssen, Wael E.; Thomas, Louise; Alexandru-Crivac, Cristina-Nicoleta et al.

Part of Journal of Natural Products, p. 566-573, 2023

• DOI for Exploring the limits of cyanobactin macrocyclase PatGmac: Cyclization of PawS-derived peptide sunflower trypsin inhibitor-1 and cyclotide kalata B1
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Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies

Eriksson, Camilla; Gunasekera, Sunithi; Muhammad, Taj; Zhang, Mingshu et al.

Part of ChemBioChem, 2023

• DOI for Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies
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The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures

Slazak, Blazej; Jedrzejska, Aleksandra; Badyra, Bogna; Shariatgorji, Reza et al.

Part of PLANTS, 2022

• DOI for The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures
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The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite

Slazak, Blazej; Jedrzejska, Aleksandra; Badyra, Bogna; Sybilska, Anna et al.

Part of Scientific Reports, 2022

• DOI for The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite
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Stability Study of Alpinia galanga Constituents and Investigation of Their Membrane Permeability by ChemGPS-NP and the Parallel Artificial Membrane Permeability Assay

Simon, Alexandra; Nghiem, Kim Szofi; Gampe, Nora; Garadi, Zsofia et al.

Part of Pharmaceutics, 2022

• DOI for Stability Study of Alpinia galanga Constituents and Investigation of Their Membrane Permeability by ChemGPS-NP and the Parallel Artificial Membrane Permeability Assay
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A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens

White, John Kerr; Muhammad, Taj; Alsheim, Emelie; Mohanty, Soumitra et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2022

• DOI for A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens
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Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum

Safa, Neda; Trobec, Tomaz.; Holland, Darren C.; Slazak, Blazej et al.

Part of Journal of Natural Products, p. 215-224, 2022

• DOI for Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum
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Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis

Jakobsson, Per-Johan; Robertson, Luke; Welzel, Janika; Zhang, Mingshu et al.

Part of Journal of Internal Medicine, p. 745-763, 2022

• DOI for Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis
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In vitro and in silico evaluation of Ononis isoflavonoids as molecules targeting the central nervous system

Gampe, Nora; David, Dominika Noemi; Takacs-Novak, Krisztina; Backlund, Anders et al.

Part of PLOS ONE, 2022

• DOI for In vitro and in silico evaluation of Ononis isoflavonoids as molecules targeting the central nervous system
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Cyclotide host-defense tailored for species and environments in violets from the Canary Islands

Slazak, Blazej; Kaltenböck, Klara; Steffen, Karin; Rogala, Martyna et al.

Part of Scientific Reports, 2021

• DOI for Cyclotide host-defense tailored for species and environments in violets from the Canary Islands
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Survival and growth of saprotrophic and mycorrhizal fungi in recalcitrant amine, amide and ammonium containing media

Stenholm, Åke; Backlund, Anders; Holmström, Sara; Backlund, Maria et al.

Part of PLOS ONE, 2021

• DOI for Survival and growth of saprotrophic and mycorrhizal fungi in recalcitrant amine, amide and ammonium containing media
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Decoding Multiple Biofunctions of Maca on Its Anti-allergic, Anti-inflammatory, Anti-thrombotic, and Pro-angiogenic Activities

Purnomo, Kartiko Arif; Korinek, Michal; Tsai, Yi-Hong; Hu, Hao-Chun et al.

Part of Journal of Agricultural and Food Chemistry, p. 11856-11866, 2021

• DOI for Decoding Multiple Biofunctions of Maca on Its Anti-allergic, Anti-inflammatory, Anti-thrombotic, and Pro-angiogenic Activities

Functional characterization of the nemertide alpha family of peptide toxins

Jacobsson, Erik; Peigneur, Steve; Andersson, Håkan; Laborde, Quentin et al.

Part of Journal of Natural Products, p. 2121-2128, 2021

• DOI for Functional characterization of the nemertide alpha family of peptide toxins

Barrettides: A Peptide Family Specifically Produced by the Deep-Sea Sponge Geodia barretti

Steffen, Karin; Laborde, Quentin; Gunasekera, Sunithi; Payne, Colton D. et al.

Part of Journal of Natural Products, p. 3138-3146, 2021

• DOI for Barrettides: A Peptide Family Specifically Produced by the Deep-Sea Sponge Geodia barretti
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Tropical vibes from Sri Lanka - cyclotides from Viola betonicifolia by transcriptome and mass spectrometry analysis

Rajendran, Sanjeevan; Slazak, Blazej; Mohotti, Supun; Strömstedt, Adam A. et al.

Part of Phytochemistry, 2021

• DOI for Tropical vibes from Sri Lanka - cyclotides from Viola betonicifolia by transcriptome and mass spectrometry analysis
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Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates

Shcherbakova, A.; Strömstedt, Adam A.; Göransson, Ulf; Gnezdilov, O. et al.

Part of World Journal of Microbiology & Biotechnology, 2021

• DOI for Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates
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Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides

Payne, Colton D.; Vadlamani, Grishma; Hajiaghaalipour, Fatemeh; Muhammad, Taj et al.

Part of RSC CHEMICAL BIOLOGY, p. 1682-1691, 2021

• DOI for Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides
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Exploring natural products-based cancer therapeutics derived from egyptian flora

El-Seedi, Hesham; Yosri, Nermeen; Khalifa, Shaden A. M.; Guo, Zhiming et al.

Part of Journal of Ethnopharmacology, 2021

• DOI for Exploring natural products-based cancer therapeutics derived from egyptian flora

Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm

Zihad, S. M. Neamul Kabir; Uddin, Shaikh Jamal; Sifat, Nazifa; Lovely, Farhana et al.

Part of Biochemistry and Biophysics Reports, 2021

• DOI for Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm
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Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

Wang, Si-Yu; Zhao, Hui; Xu, Hong-Tao; Han, Xiao-Dong et al.

Part of Frontiers in Pharmacology, 2021

• DOI for Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses
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Editorial: Natural Antimicrobial Peptides: Hope for New Antibiotic Lead Molecules

Uddin, Shaikh Jamal; Shilpi, Jamil Ahmad; Nahar, Lutfun; Sarker, Satyajit D. et al.

Part of Frontiers in Pharmacology, 2021

• DOI for Editorial: Natural Antimicrobial Peptides: Hope for New Antibiotic Lead Molecules
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Recent insights into chemical and pharmacological studies of bee bread

Khalifa, Shaden A. M.; Elashal, Mohamed; Kieliszek, Marek; Ghazala, Naglaa E. et al.

Part of Trends in Food Science & Technology, p. 300-316, 2020

• DOI for Recent insights into chemical and pharmacological studies of bee bread

Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae)

Robertson, Luke P.; Moodie, Lindon W. K.; Holland, Darren C.; Jandér, K. Charlotte et al.

Part of Journal of Natural Products, p. 1305-1308, 2020

• DOI for Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae)
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Revisiting the phylogeny of Dipsacales: New insights from phylogenomic analyses of complete plastomic sequences

Xiang, Chun‐Lei; Dong, Hong‐Jin; Landrein, Sven; Zhao, Fei et al.

Part of Journal of Systematics and Evolution, p. 103-117, 2020

• DOI for Revisiting the phylogeny of Dipsacales: New insights from phylogenomic analyses of complete plastomic sequences

The life cycle of cyclotides: biosynthesis and turnover in plant cells

Slazak, Blazej; Haugmo, Tobias; Badyra, Bogna; Göransson, Ulf

Part of Plant Cell Reports, p. 1359-1367, 2020

• DOI for The life cycle of cyclotides: biosynthesis and turnover in plant cells
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Bisabolane sesquiterpenes from the leaves of Lindera benzoin reduce prostaglandin E2 formation in A549 cells

Henz Ryen, Astrid; Goels, Thomas; Steinmetz, Julia; Tahir, Ammar et al.

Part of Phytochemistry Letters, p. 6-11, 2020

• DOI for Bisabolane sesquiterpenes from the leaves of Lindera benzoin reduce prostaglandin E2 formation in A549 cells

Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens

Mohotti, Supun; Rajendran, Sanjeevan; Muhammad, Taj; Strömstedt, Adam A. et al.

Part of Journal of Ethnopharmacology, 2020

• DOI for Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens
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Evaluating Antimycobacterial Screening Schemes Using Chemical Global Positioning System-Natural Product Analysis

Alajlani, Muaaz Mutaz; Backlund, Anders

Part of Molecules, 2020

• DOI for Evaluating Antimycobacterial Screening Schemes Using Chemical Global Positioning System-Natural Product Analysis
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Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects

Afroz, Mohasana; Akter, Sanzida; Ahmed, Asif; Rouf, Razina et al.

Part of Frontiers in Pharmacology, 2020

• DOI for Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects
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Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability

Gunasekera, Sunithi; Muhammad, Taj; Strömstedt, Adam A.; Rosengren, K. Johan et al.

Part of Frontiers in Microbiology, 2020

• DOI for Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability
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The Toxins of Nemertean Worms

Göransson, Ulf; Jacobsson, Erik; Strand, Malin; Andersson, Hakan S.

Part of Toxins, 2019

• DOI for The Toxins of Nemertean Worms
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Marine Natural Products: A Source of Novel Anticancer Drugs

Khalifa, Shaden A. M.; Elias, Nizar; Farag, Mohamed A.; Chen, Lei et al.

Part of Marine Drugs, 2019

• DOI for Marine Natural Products: A Source of Novel Anticancer Drugs
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Charting Angiosperm Chemistry: Evolutionary Perspective on Specialized Metabolites Reflected in Chemical Property Space

Henz Ryen, Astrid; Backlund, Anders

Part of Journal of Natural Products, p. 798-812, 2019

• DOI for Charting Angiosperm Chemistry: Evolutionary Perspective on Specialized Metabolites Reflected in Chemical Property Space

Briaviolides K-N, New Briarane-Type Diterpenoids from Cultured Octocoral Briareum violaceum

Xu, Jing-Hao; Lai, Kuei-Hung; Su, Yin-Di; Chang, Yu-Chia et al.

Part of Marine Drugs, 2018

• DOI for Briaviolides K-N, New Briarane-Type Diterpenoids from Cultured Octocoral Briareum violaceum
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Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis

Gunasekera, Sunithi; Fernandes-Cerqueira, Catia; Wennmalm, Stefan; Wahamaa, Heidi et al.

Part of ACS Chemical Biology, p. 1525-1535, 2018

• DOI for Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis

Repertoire Studies in Rheumatoid Arthritis Reveal B-Cell Distortions and Baseline Shifts in Unmutated IgG

Wang, Yan; Lloyd, Katy A.; Gunasekera, Sunithi; Eriksson, Camilla et al.

Part of Arthritis & Rheumatology, 2018

Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity

Gunasekera, Sunithi; Muhammad, Taj; Strömstedt, Adam A.; Rosengren, K. Johan et al.

Part of ChemBioChem (Print), p. 931-939, 2018

• DOI for Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity

Peptide ion channel toxins from the bootlace worm, the longest animal on Earth

Jacobsson, Erik; Andersson, Håkan S.; Strand, Malin; Peigneur, Steve et al.

Part of Scientific Reports, 2018

• DOI for Peptide ion channel toxins from the bootlace worm, the longest animal on Earth
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How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System

Slazak, Blazej; Kapusta, Malgorzata; Strömstedt, Adam A.; Slomka, Aneta et al.

Part of Frontiers in Plant Science, 2018

• DOI for How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System
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Single-step purification of cyclotides using affinity chromatography

Uddin, Shaikh Jamal; Muhammad, Taj; Shafiullah, Md; Slazak, Blazej et al.

Part of Biopolymers, 2017

• DOI for Single-step purification of cyclotides using affinity chromatography

Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides

Malik, Sohaib Zafar; Linkevicius, Marius; Göransson, Ulf; Andersson, Dan I

Part of Antimicrobial Agents and Chemotherapy, 2017

• DOI for Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides
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