Karin Stensjö
Universitetslektor vid Institutionen för kemi - Ångström; Molekylär biomimetik; Mikrobiell Kemi
- Telefon:
- 018-471 65 86
- E-post:
- karin.stensjo@kemi.uu.se
- Besöksadress:
- Ångströmlaboratoriet, Lägerhyddsvägen 1
75120 Uppsala - Postadress:
- Box 523
75120 Uppsala
- Akademiska meriter:
- PhD, Docent
- CV:
- Ladda ned CV
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Kort presentation
Denna text finns inte på svenska, därför visas den engelska versionen.
Associate Professor in Microbial chemistry. The research is focused on cyanobacteria; metabolic and regulatory dynamics, redox regulation, adaptations to changes in the environment with the aim to identify novel targets for genetic engineering of cyanobacteria for biotechnological applications, such as production of biofuels from solar energy and water.
Biografi
Denna text finns inte på svenska, därför visas den engelska versionen.
My interest in cyanobacterial research started when I did my master project “Localization of the nifH transcript in the cyanobacterium Anabaena PCC 7120” in the lab of Prof Lindblad, and consequently received a MSc in Biology from Uppsala University in 1994. Since then I have gathered a broad knowledge in molecular biology, biochemistry, microbiology and plant physiology. I did my PhD at the Swedish Agricultural University (SLU) in Prof. Lisbeth Jonssons group, where I studied the chemical interaction of plants and pests. I received my PhD in Plant Physiology in 2000. I did postdoctoral studies at Copenhagen University(former name KVL)) in the group of Prof Birger Lindberg Møller where I used molecular and biochemical techniques to engineer and characterize the biosynthesis of natural products in plants. I have been a research scientist since 2003, and I have continued in exploring natural products, but now; biofuels from cyanobacteria. Since December 2012 I am an Associate Professor (senior lecturer) in Microbial Chemistry at the Department of Chemistry-Ångström Laboratory, Uppsala University. In my research I am exploring the potential of biofuels production in cyanobacteria by a systems biology approach.
Publikationer
Urval av publikationer
- A HupS-GFP fusion protein demonstrates a heterocyst-specific localization of the uptake hydrogenase in Nostoc punctiforme (2011)
- Metabolic Adaptations in a H-2 Producing Heterocyst-Forming Cyanobacterium (2011)
- The CyAbrB transcription factor CalA regulates the iron superoxide dismutase in Nostoc sp. strain PCC 7120 (2010)
- Quantitative overview of N2 fixation in Nostoc punctiforme ATCC 29133 through cellular enrichments and iTRAQ shotgun proteomics (2009)
- Quantitative shotgun proteomics of enriched heterocysts from Nostoc sp. PCC 7120 using 8-Plex isobaric peptide tags (2008)
- An iTRAQ-based quantitative analysis to elaborate the proteomic response of Nostoc sp PCC 7120 under N-2 fixing conditions (2007)
Senaste publikationer
- Machine learning predicts system-wide metabolic flux control in cyanobacteria (2024)
- Optimal energy and redox metabolism in the cyanobacterium Synechocystis sp. PCC 6803 (2023)
- Synthetic biology in marine cyanobacteria (2022)
- A combined photobiological-photochemical route to C10 cycloalkane jet fuels from carbon dioxide via isoprene (2022)
- Differential catalase activity and tolerance to hydrogen peroxide in the filamentous cyanobacteria Nostoc punctiforme ATCC 29113 and Anabaena sp. PCC 7120 (2022)
Alla publikationer
Artiklar
- Machine learning predicts system-wide metabolic flux control in cyanobacteria (2024)
- Optimal energy and redox metabolism in the cyanobacterium Synechocystis sp. PCC 6803 (2023)
- Synthetic biology in marine cyanobacteria (2022)
- A combined photobiological-photochemical route to C10 cycloalkane jet fuels from carbon dioxide via isoprene (2022)
- Differential catalase activity and tolerance to hydrogen peroxide in the filamentous cyanobacteria Nostoc punctiforme ATCC 29113 and Anabaena sp. PCC 7120 (2022)
- Photoautotrophic production of renewable ethylene by engineered cyanobacteria (2021)
- Photosynthetic hydrogen production: Novel protocols, promising engineering approaches and application of semi‐synthetic hydrogenases (2021)
- Isobutene production in Synechocystis sp. PCC 6803 by introducing α-ketoisocaproate dioxygenase from Rattus norvegicus (2021)
- Doing synthetic biology with photosynthetic microorganisms (2021)
- The Dps4 from Nostoc punctiforme ATCC 29133 is a member of His-type FOC containing Dps protein class that can be broadly found among cyanobacteria (2019)
- Structural diffusion properties of two atypical Dps from the cyanobacterium Nostoc punctiforme disclose interactions with ferredoxins and DNA (2019)
- Differential biochemical properties of three canonical Dps proteins from the cyanobacterium Nostoc punctiforme suggest distinct cellular functions (2018)
- Homologous overexpression of NpDps2 and NpDps5 increases the tolerance for oxidative stress in the multicellular cyanobacterium Nostoc punctiforme (2018)
- Harnessing transcription for bioproduction in cyanobacteria (2018)
- Design and characterization of a synthetic minimal promoter for heterocyst-specific expression in filamentous cyanobacteria (2018)
- The two Dps proteins, NpDps2 and NpDps5, are involved in light-induced oxidative stress tolerance in the N2-fixing cyanobacterium Nostoc punctiforme (2016)
- Differential transcriptional regulation of orthologous dps genes from two closely related heterocyst-forming cyanobacteria (2015)
- Molecular Cloning and Biochemical Characterization of the Iron Superoxide Dismutase from the Cyanobacterium Nostoc punctiforme ATCC 29133 and Its Response to Methyl Viologen-Induced Oxidative Stress (2015)
- Cellular and functional specificity among ferritin-like proteins in the multicellular cyanobacterium Nostoc punctiforme. (2014)
- Production of Squalene in Synechocystis sp. PCC 6803 (2014)
- A high constitutive catalase activity confers resistance to methyl viologen-promoted oxidative stress in a mutant of the cyanobacterium Nostoc punctiforme ATCC 29133 (2014)
- Analysis of the early heterocyst Cys-proteome in the multicellular cyanobacterium Nostoc punctiforme reveals novel insights into the division of labor within diazotrophic filaments (2014)
- CRISPR in the extended hyp-operon of the cyanobacterium Nostoc sp. strain PCC 7120, characteristics and putative function(s) (2012)
- HupW Protease Specifically Required for Processing of the Catalytic Subunit of the Uptake Hydrogenase in the Cyanobacterium Nostoc sp Strain PCC 7120 (2012)
- Design, Engineering, and Construction of Photosynthetic Microbial Cell Factories for Renewable Solar Fuel Production (2012)
- A HupS-GFP fusion protein demonstrates a heterocyst-specific localization of the uptake hydrogenase in Nostoc punctiforme (2011)
- Metabolic Adaptations in a H-2 Producing Heterocyst-Forming Cyanobacterium (2011)
- Synthetic Biology in Cyanobacteria (2011)
- Transcript analysis of the extended hyp-operons in the cyanobacteria Nostoc sp. strain PCC 7120 and Nostoc punctiforme ATCC 29133 (2011)
- Modeling Photosystem I with the alternative reaction center protein PsaB2 in the nitrogen fixing cyanobacterium Nostoc punctiforme (2011)
- The CyAbrB transcription factor CalA regulates the iron superoxide dismutase in Nostoc sp. strain PCC 7120 (2010)
- CalA, a cyanobacterial AbrB protein, interacts with the upstream region of hypC and acts as a repressor of its transcription in the cyanobacterium Nostoc sp. strain PCC 7120 (2010)
- Electron transfer protein complexes in the thylakoid membranes of heterocysts from the cyanobacterium Nostoc punctiforme (2009)
- Diversity and transcription of proteases involved in the maturation of hydrogenases in Nostoc punctiforme ATCC 29133 and Nostoc sp strain PCC 7120 (2009)
- Characterization of the hupSL promoter activity in Nostoc punctiforme ATCC 29133 (2009)
- Characterization of the hupSL promoter activity in Nostoc punctiforme ATCC 29133 (2009)
- Biomimetic and Microbial Approaches to Solar Fuel Generation (2009)
- Quantitative overview of N2 fixation in Nostoc punctiforme ATCC 29133 through cellular enrichments and iTRAQ shotgun proteomics (2009)
- Transcription of the extended hyp-operon in Nostoc sp. strain PCC 7120 (2008)
- Quantitative shotgun proteomics of enriched heterocysts from Nostoc sp. PCC 7120 using 8-Plex isobaric peptide tags (2008)
- Photosynthetic electron transport properties of an uptake hydrogenase deletion mutant of Nostoc punctiforme PCC 73102 (2007)
- An iTRAQ-based quantitative analysis to elaborate the proteomic response of Nostoc sp PCC 7120 under N-2 fixing conditions (2007)
- Reconstitution of cyanogenesis in barley and its implications for resistance against the barley powdery mildew fungus (2006)
- Biosynthesis of the Nitrile Glucosides Rhodiocyanoside A and D and the Cyanogenic Glucosides Lotaustralin and Linamarin in Lotus japonicus. (2004)
- Plant-Insect Interactions as a Response to Metabolic Engineering of Natural Product Synthesis studied by Functional Genomics in Lotus japonicus (2003)
- Aphid infestation induces PR-proteins differently in barley susceptible or resistant to the birdcherry-oat aphid (Rhopalosiphum padi) (2000)
- Settling behaviour of Rhopalosiphum padi in relation to cyanogenic glycosides and gramine contents in barley (1998)
- Cyanogenic glycosides and their metabolic enzymes in barley in relation to nitrogen levels. (1997)
- The CyAbrB transcription factor Alr0946 regulates the iron superoxide dismutase in Nostoc sp. strain PCC 7120
- A HupS-GFP fusion protein demonstrates a heterocyst specific localisation of the uptake hydrogenase in the cyanobacterium Nostoc punctiforme
- Transcriptional analysis of the hydrogenase specific proteases in Nostoc punctiforme and Nostoc sp. strain PCC 7120
- The protease HupW is specific for the uptake hydrogenase in Nostoc sp. strain PCC 7120
- An in-silico study of the NtcA transcription factor family in filamentous cyanobacteria
- Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803
- Structural diffusion properties of two atypical Dps from the cyanobacterium Nostoc punctiforme disclose interactions with ferredoxins and DNA
Kapitel
Konferenser
- Global quantitative proteomic analyses of Nostoc punctiforme PCC 73102 under diazotrophic conditions using iTRAQ and label-free techniques (2008)
- An 8-plex iTRAQ Shotgun Proteomics Investigation of N2-fixing Heterocysts in the Cyanobacterium Nostoc sp. PCC 7120 (2007)
- Cellular scale qualitative shotgun proteomic analysis of Nostoc sp. PCC 7120 isolated heterocysts and filaments under N2 deficient conditions using 8-plex isobaric peptide tags (2007)
