Tobias Bergström

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Ingår i Cell Death and Differentiation, s. 1915-1929, 2025

• DOI för The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
• Ladda ner fulltext (pdf) av The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma

Lindell, Emma; Guo, Jing; Zhao, Miao; Rameika, Natallia et al.

Ingår i Cell Death and Disease, 2025

• DOI för Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma
• Ladda ner fulltext (pdf) av Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma

Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Ingår i Scientific Reports, 2024

• DOI för Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
• Ladda ner fulltext (pdf) av Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Ingår i Cancer Research, s. 4586-4603, 2022

• DOI för Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Ladda ner fulltext (pdf) av Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2

Berg, Tracy J.; Marques, Carolina; Pantazopoulou, Vasiliki; Johansson, Elinn et al.

Ingår i Cancer Research, s. 2101-2115, 2021

• DOI för The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Ingår i Cell Death and Differentiation, s. 1915-1929, 2025

• DOI för The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
• Ladda ner fulltext (pdf) av The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma

Lindell, Emma; Guo, Jing; Zhao, Miao; Rameika, Natallia et al.

Ingår i Cell Death and Disease, 2025

• DOI för Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma
• Ladda ner fulltext (pdf) av Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma

Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Ingår i Scientific Reports, 2024

• DOI för Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
• Ladda ner fulltext (pdf) av Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Borgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao et al.

Ingår i Cancer Research, s. 4586-4603, 2022

• DOI för Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma
• Ladda ner fulltext (pdf) av Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2

Berg, Tracy J.; Marques, Carolina; Pantazopoulou, Vasiliki; Johansson, Elinn et al.

Ingår i Cancer Research, s. 2101-2115, 2021

• DOI för The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2

A molecularly distinct subset of glioblastoma requires serum-containing media to establish sustainable bona fide glioblastoma stem cell cultures

Maturi, Naga Prathyusha; Tan, E-Jean; Xie, Yuan; Sundström, Anders et al.

Ingår i Glia, s. 1228-1240, 2020

• DOI för A molecularly distinct subset of glioblastoma requires serum-containing media to establish sustainable bona fide glioblastoma stem cell cultures

Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

Niklasson, Mia; Bergström, Tobias; Jarvius, Malin; Sundström, Anders et al.

Ingår i Journal of Pathology, s. 295-307, 2019

• DOI för Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Čančer, Matko; Hutter, Sonja; Holmberg Olausson, Karl; Rosén, Gabriela et al.

Ingår i Cell Stem Cell, s. 855-870, 2019

• DOI för Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
• Ladda ner fulltext (pdf) av Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Baskaran, Sathishkumar; Mayrhofer, Markus; Göransson Kultima, Hanna; Bergström, Tobias et al.

Ingår i Neuro-Oncology, s. 1080-1091, 2018

• DOI för Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
• Ladda ner fulltext (pdf) av Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Xiong, Anqi; Kundu, Soumi; Forsberg, Maud; Xiong, Yuyuan et al.

Ingår i Matrix Biology, s. 92-104, 2017

• DOI för Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Segerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergström, Tobias et al.

Ingår i Cell Reports, s. 2994-3009, 2016

• DOI för Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
• Ladda ner fulltext (pdf) av Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Yuan; Bergström, Tobias; Jiang, Yiwen; Johansson, Patrik et al.

Ingår i EBioMedicine, s. 1351-1363, 2015

• DOI för The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
• Ladda ner fulltext (pdf) av The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Põlajeva, Jelena; Bergström, Tobias; Edqvist, Per-Henrik; Lundequist, Anders et al.

Ingår i Molecular Oncology, s. 50-58, 2014

• DOI för Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Developmentally regulated collagen/integrin interactions confer adhesive properties to early postnatal neural stem cells

Bergström, Tobias; Holmqvist, Karin; Tararuk, Tatsiana; Johansson, Staffan et al.

Ingår i Biochimica et Biophysica Acta - General Subjects, s. 2526-2532, 2014

• DOI för Developmentally regulated collagen/integrin interactions confer adhesive properties to early postnatal neural stem cells

Exocyst Complex Component 3-like 2 (EXOC3L2) Associates with the Exocyst Complex and Mediates Directional Migration of Endothelial Cells

Barkefors, Irmeli; Fredlund Fuchs, Peder; Heldin, Johan; Bergström, Tobias et al.

Ingår i Journal of Biological Chemistry, s. 24189-24199, 2011

• DOI för Exocyst Complex Component 3-like 2 (EXOC3L2) Associates with the Exocyst Complex and Mediates Directional Migration of Endothelial Cells

Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells

Niklasson, Mia; Bergström, Tobias; Zhang, X-Q; Gustafsdottir, Sigrun M et al.

Ingår i Experimental Cell Research, s. 2779-2789, 2010

• DOI för Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells

Neural stem cells: Brain building blocks and beyond

Bergström, Tobias; Forsberg-Nilsson, Karin

Ingår i Upsala Journal of Medical Sciences, s. 132-142, 2012

• DOI för Neural stem cells: Brain building blocks and beyond

Modeling Neural Stem Cell and Glioma Biology

Bergström, Tobias

2013

• Ladda ner fulltext (pdf) av Modeling Neural Stem Cell and Glioma Biology

A divergent effect of PDGF-AA and -BB on differentiating neural stem and progenitor cells

Larsson, Jimmy; Bergström, Tobias; Forsberg-Nilsson, Karin

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.

Paired glioblastoma cell cultures of the fluorescent bulk tumor and non-fluorescent tumor margin display differential phenotypes and cell states across patients

Neves, Inês; Lu, Xi; Maturi, Nagaprathyusha; Dang, Yonglong et al.