Sherry Mowbray

Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis

Courtiol-Legourd, Stephanie; Mariano, Sandrine; Foret, Johanna; Roos, Annette K. et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, 2024

• DOI för Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis

Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Benediktsdottir, Andrea; Sooriyaarachchi, Sanjeewani; Cao, Sha; Ottosson, Nina E. et al.

Ingår i European Journal of Medicinal Chemistry, 2024

• DOI för Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
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Bacterial type I signal peptidase inhibitors-Optimized hits from nature

Szalaj, Natalia; Benediktsdottir, Andrea; Rusin, Dominika; Karlén, Anders et al.

Ingår i European Journal of Medicinal Chemistry, 2022

• DOI för Bacterial type I signal peptidase inhibitors-Optimized hits from nature

Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Lu, Lu; Åkerbladh, Linda; Ahmad, Shabbir; Konda, Vivek et al.

Ingår i ACS - Infectious Diseases, s. 482-498, 2022

• DOI för Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)
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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria

Huseby, Douglas L.; Cao, Sha; Zamaratski, Edouard; Sooriyaarachchi, Sanjeewani et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI för Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
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Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis

Courtiol-Legourd, Stephanie; Mariano, Sandrine; Foret, Johanna; Roos, Annette K. et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, 2024

• DOI för Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis

Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors

Benediktsdottir, Andrea; Sooriyaarachchi, Sanjeewani; Cao, Sha; Ottosson, Nina E. et al.

Ingår i European Journal of Medicinal Chemistry, 2024

• DOI för Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors
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Bacterial type I signal peptidase inhibitors-Optimized hits from nature

Szalaj, Natalia; Benediktsdottir, Andrea; Rusin, Dominika; Karlén, Anders et al.

Ingår i European Journal of Medicinal Chemistry, 2022

• DOI för Bacterial type I signal peptidase inhibitors-Optimized hits from nature

Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Lu, Lu; Åkerbladh, Linda; Ahmad, Shabbir; Konda, Vivek et al.

Ingår i ACS - Infectious Diseases, s. 482-498, 2022

• DOI för Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)
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Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation

Benediktsdottir, Andrea; Lu, Lu; Cao, Sha; Zamaratski, Edouard et al.

Ingår i European Journal of Medicinal Chemistry, 2021

• DOI för Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation
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Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase

Szałaj, Natalia; Lu, Lu; Benediktsdottir, Andrea; Zamaratski, Edouard et al.

Ingår i European Journal of Medicinal Chemistry, s. 1346-1360, 2018

• DOI för Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)

De Rosa, Maria; Lu, Lu; Zamaratski, Edouard; Szałaj, Natalia et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 897-911, 2017

• DOI för Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB)
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Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.

Singh, Vinayak; Dhar, Neeraj; Pató, János; Kolly, Gaëlle S et al.

Ingår i Molecular Microbiology, s. 13-25, 2017

• DOI för Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with -Arylpropyl Analogues of Fosmidomycin

Sooriyaarachchi, Sanjeewani; Chofor, Rene; Risseeuw, Martijn D. P.; Bergfors, Terese et al.

Ingår i ChemMedChem, s. 2024-2036, 2016

• DOI för Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with -Arylpropyl Analogues of Fosmidomycin
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Expanding the catalytic triad in epoxide hydrolases and related enzymes

Amrein, Beat A.; Bauer, Paul; Duarte, Fernanda; Janfalk Carlsson, Åsa et al.

Ingår i ACS Catalysis, s. 5702-5713, 2015

• DOI för Expanding the catalytic triad in epoxide hydrolases and related enzymes
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Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase

Chofor, Rene; Sooriyaarachchi, Sanjeewani; Risseeuw, Martijn D. P.; Bergfors, Terese et al.

Ingår i Journal of Medicinal Chemistry, s. 2988-3001, 2015

• DOI för Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase
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Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Russo, Francesco; Gising, Johan; Åkerbladh, Linda; Roos, Annette K. et al.

Ingår i ChemistryOpen, s. 342-362, 2015

• DOI för Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents
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Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development

Hsiao, An-Shan; Haslam, Richard P.; Michaelson, Louise V.; Liao, Pan et al.

Ingår i Bioscience Reports, s. 865-877, 2014

• DOI för Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development
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DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues

Jansson, Anna; Więckowska, Anna; Björkelid, Christofer; Yahiaoui, Samir et al.

Ingår i Journal of Medicinal Chemistry, s. 6190-6199, 2013

• DOI för DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues
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Structural studies on Mycobacterium tuberculosis DXR in complex with the antibiotic FR-900098

Björkelid, Christofer; Bergfors, Terese; Unge, Torsten; Mowbray, Sherry L. et al.

Ingår i Acta Crystallographica Section D, s. 134-143, 2012

• DOI för Structural studies on Mycobacterium tuberculosis DXR in complex with the antibiotic FR-900098
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Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Nordqvist, Anneli; Nilsson, Mikael T.; Lagerlund, Olof; Muthas, Daniel et al.

Ingår i MedChemComm, s. 620-626, 2012

• DOI för Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Gising, Johan; Nilsson, Mikael T; Odell, Luke R; Yahiaoui, Samir et al.

Ingår i Journal of Medicinal Chemistry, s. 2894-2898, 2012

• DOI för Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors
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Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase

Andaloussi, Mounir; Henriksson, Lena M.; Wieckowska, Anna; Lindh, Martin et al.

Ingår i Journal of Medicinal Chemistry, s. 4964-4976, 2011

• DOI för Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase
• Ladda ner fulltext (pdf) av Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase

Structural and functional studies of mycobacterial IspD enzymes

Björkelid, Christofer; Bergfors, Terese; Henriksson, Lena M.; Stern, Ana Laura et al.

Ingår i Acta Crystallographica Section D, s. 403-414, 2011

• DOI för Structural and functional studies of mycobacterial IspD enzymes
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Expression and beta-glucan binding properties of Scots pine (Pinus sylvestris L.) antimicrobial protein (Sp-AMP)

Sooriyaarachchi, Sanjeewani; Jaber, Emad; Covarrubias, Adrian Suarez; Ubhayasekera, Wimal et al.

Ingår i Plant Molecular Biology, s. 33-45, 2011

• DOI för Expression and beta-glucan binding properties of Scots pine (Pinus sylvestris L.) antimicrobial protein (Sp-AMP)
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Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family

Stern, Ana Laura; Naworyta, Agata; Cazzulo, Juan J.; Mowbray, Sherry L.

Ingår i The FEBS Journal, s. 793-808, 2011

• DOI för Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family
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Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors

Nordqvist, Anneli; Björkelid, Christofer; Andaloussi, Mounir; Jansson, Anna M. et al.

Ingår i Journal of Organic Chemistry, s. 8986-8998, 2011

• DOI för Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors
• Ladda ner fulltext (pdf) av Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors

Zinc ions bind to and inhibit activated protein C

Zhu, Tianqing; Ubhayasekera, Wimal; Nickolaus, Noëlle; Sun, Wei et al.

Ingår i Thrombosis and Haemostasis, s. 544-553, 2010

• DOI för Zinc ions bind to and inhibit activated protein C
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Conformational Changes and Ligand Recognition of Escherichia coli d-Xylose Binding Protein Revealed

Sooriyaarachchi, Sanjeewani; Ubhayasekera, Wimal; Park, Chankyu; Mowbray, Sherry

Ingår i Journal of Molecular Biology, s. 657-668, 2010

• DOI för Conformational Changes and Ligand Recognition of Escherichia coli d-Xylose Binding Protein Revealed
• Ladda ner fulltext (pdf) av Conformational Changes and Ligand Recognition of Escherichia coli d-Xylose Binding Protein Revealed

Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors

Nilsson, Mikael T.; Krajewski, Wojciech W.; Srinivasa, Bachally R.; Yahiaoui, Samir et al.

Ingår i Journal of Molecular Biology, s. 504-513, 2009

• DOI för Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors
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Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c

Carta, Fabrizio; Maresca, Alfonso; Covarrubias, Adrian Suarez; Mowbray, S.L. et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 6649-6654, 2009

• DOI för Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c

Competitive inhibitors of type B ribose 5-phosphate isomerases: design, synthesis and kinetic evaluation of new D-allose and D-allulose 6-phosphate derivatives

Mariano, Sandrine; Roos, Annette K.; Mowbray, Sherry L.; Salmon, Laurent

Ingår i Carbohydrate Research, s. 869-880, 2009

• DOI för Competitive inhibitors of type B ribose 5-phosphate isomerases: design, synthesis and kinetic evaluation of new D-allose and D-allulose 6-phosphate derivatives

The first crystal structures of a family 19 class IV chitinase: the enzyme from Norway spruce

Ubhayasekera, Wimal; Rawat, Reetika; Ho, Sharon Wing Tak; Wiweger, Malgorzata et al.

Ingår i Plant Molecular Biology, s. 277-289, 2009

• DOI för The first crystal structures of a family 19 class IV chitinase: the enzyme from Norway spruce
• Ladda ner fulltext (pdf) av The first crystal structures of a family 19 class IV chitinase: the enzyme from Norway spruce

X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-β-d- galactopyranoside

Sooriyaarachchi, Sanjeewani; Ubhayasekera, Wimal; Boos, Winfried; Mowbray, Sherry

Ingår i The FEBS Journal, s. 2116-2124, 2009

• DOI för X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-β-d- galactopyranoside

Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability

Thomaeus, Ann; Naworyta, Agata; Mowbray, Sherry L.; Widersten, Mikael

Ingår i Protein Science, s. 1275-1284, 2008

• DOI för Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability
• Ladda ner fulltext (pdf) av Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability

X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation

Ericsson, Daniel J.; Kasrayan, Alex; Johansson, Patrik; Bergfors, Terese et al.

Ingår i Journal of Molecular Biology, s. 109-119, 2008

• DOI för X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation
• Ladda ner fulltext (pdf) av X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation

Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design

Krajewski, Wojciech W.; Collins, Ruairi; Holmberg-Schiavone, Lovisa; Jones, T. Alwyn et al.

Ingår i Journal of Molecular Biology, s. 217-228, 2008

• DOI för Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design
• Ladda ner fulltext (pdf) av Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design

Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

Nordqvist, Anneli; Nilsson, Mikael T.; Röttger, Svenja; Odell, Luke R. et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5501-5513, 2008

• DOI för Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery
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Structural, biochemical and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis

Covarrubias, Adrian Suarez; Högbom, Martin; Bergfors, Terese; Carroll, Paul et al.

Ingår i Journal of Molecular Biology, s. 622-633, 2008

• DOI för Structural, biochemical and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis
• Ladda ner fulltext (pdf) av Structural, biochemical and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis

D-ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not

Roos, Annette K.; Mariano, Sandrine; Kowalinski, Eva; Salmon, Laurent et al.

Ingår i Journal of Molecular Biology, s. 667-679, 2008

• DOI för D-ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not
• Ladda ner fulltext (pdf) av D-ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not

Crystal structures of a family 19 chitinase from Brassica juncea show flexibility of binding cleft loops

Ubhayasekera, Wimal; Tang, Ce Mun; Ho, Sharon W. T.; Berglund, Gunnar et al.

Ingår i The FEBS Journal, s. 3695-3703, 2007

• DOI för Crystal structures of a family 19 chitinase from Brassica juncea show flexibility of binding cleft loops

Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis

Henriksson, Lena M.; Unge, Torsten; Carlsson, Jens; Åqvist, Johan et al.

Ingår i Journal of Biological Chemistry, s. 19905-19916, 2007

• DOI för Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis

Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

Lagerlund, Olof; Odell, Luke R.; Mowbray, Sherry L.; Nilsson, Mikael T. et al.

Ingår i Combinatorial chemistry & high throughput screening, s. 783-789, 2007

• DOI för Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target.

Henriksson, Lena M; Björkelid, Christofer; Mowbray, Sherry L; Unge, Torsten

Ingår i Acta Crystallogr D Biol Crystallogr, s. 807-13, 2006

X-ray structure of potato epoxide hydrolase sheds light on its substrate specificity

Mowbray, Sherry L.; Elfström, Lisa; Ahlgren, Kerstin; Andersson, Evalena et al.

Ingår i Protein Science, s. 1628-1637, 2006

• DOI för X-ray structure of potato epoxide hydrolase sheds light on its substrate specificity

The 1.9 Å resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target

Henriksson, Lena M.; Björkelid, Christofer; Mowbray, Sherry L.; Unge, Torsten

Ingår i Acta Crystallogr. Section D Biol. Crystallogr., s. 807-813, 2006

Structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights

Krajewski, Wojciech W; Jones, T Alwyn; Mowbray, Sherry L

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 10499-10504, 2005

• DOI för Structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights

Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.

Suarez Covarrubias, Adrian; Larsson, Anna M.; Högbom, Martin; Lindberg, Jimmy et al.

Ingår i J Biol Chem, s. 18782-9, 2005

Structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights

Krajewski, Wojciech W.; Jones, T. Alwyn; Mowbray, Sherry L.

Ingår i Proc. Natl. Acad. Sci. USA, s. 10499-10504, 2005

Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis

Johansson, Patrik; Unge, Torsten; Cronin, Annette; Arand, Michael et al.

Ingår i J Mol Biol, s. 1048-56, 2005

Competitive inhibitors of Mycobacterium tuberculosis ribose-5-phosphate isomerase

Roos, Annette K; Burgos, Emmanuel; Ericsson, Daniel J; Salmon, Laurent et al.

Ingår i J Biol Chem, s. 6416-22, 2005

Synthesis of 5-deoxy-5-phospho-D-ribonohydroxamic acid : a new competitive and selective inhibitor of type b ribose-5-phosphate isomerase from Mycobacterium tuberculosis

Burgos, Emmanuel; Roos, Annette K.; Mowbray, Sherry L.; Salmon, Laurent

Ingår i Tetrahedron letters, s. 3691-3694, 2005

X-ray structures of the maltose-maltodextrin binding protein of the thermoacidophilic bacterium Alicyclobacillus acidocaldarius provide insight into acid stability of proteins

Schäfer, Karsten; Magnusson, Ulrika; Scheffel, Frank; Schiefner, André et al.

Ingår i Journal of Molecular Cell Biology, s. 261-274, 2004

• DOI för X-ray structures of the maltose-maltodextrin binding protein of the thermoacidophilic bacterium Alicyclobacillus acidocaldarius provide insight into acid stability of proteins

X-ray structures of the leucine-binding protein illustrate conformational changes and the basis of ligand specificity.

Magnusson, Ulrika; Salopek-Sondi, Branka; Luck, Linda A; Mowbray, Sherry L

Ingår i J Biol Chem, s. 8747-52, 2004

Mycobacterium tuberculosis ribose-5-phosphate isomerase has a known fold, but a novel active site

Roos, Annette; Andersson, Evalena; Bergfors, Terese; Jacobsson, Micael et al.

Ingår i Journal of Molecular Biology, s. 799-809, 2004

Mycobacterium tuberculosis ribose-5-phosphate isomerase has a known fold, but a novel active site.

Roos, Annette K; Andersson, C Evalena; Bergfors, Terese; Jacobsson, Micael et al.

Ingår i J Mol Biol, s. 799-809, 2004

X-ray structure of peptidyl-prolyl cis-trans isomerase A from Mycobacterium tuberculosis.

Henriksson, Lena M; Johansson, Patrik; Unge, Torsten; Mowbray, Sherry L

Ingår i Eur J Biochem, s. 4107-13, 2004

Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle

Zhang, Rong guang; Andersson, C Evalena; Savchenko, Alexei; Skarina, Tatiana et al.

Ingår i Structure, s. 31-42, 2003

• DOI för Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle

The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction

Zhang, Rong-Guang; Andersson, C Evalena; Skarina, Tatiana; Evdokimova, Elena et al.

Ingår i Journal of Molecular Biology, 2003

• DOI för The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction

Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site.

Arand, Michael; Hallberg, B Martin; Zou, Jinyu; Bergfors, Terese et al.

Ingår i EMBO Journal, s. 2583-2592, 2003

• DOI för Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site.

The telltale structures of epoxide hydrolases

Arand, M.; Cronin, A; Oesch, F; Mowbray, Sherry L et al.

Ingår i Drug metabolism reviews (Softcover ed.), s. 365-383, 2003

• DOI för The telltale structures of epoxide hydrolases

A missense mutation in ftsZ differentially affects vegetative and developmentally controlled cell division in Streptomyces coelicolor

Grantcharova, N.; Ubhayasekera, W.; Mowbray, S.L.; McCormick, J. R. et al.

Ingår i Molecular Microbiology, s. 645-656, 2003

Activation of Ribokinase by Monovalent Cations

Andersson, C. Evalena; Mowbray, Sherry L.

Ingår i Journal of Molecular Biology, s. 409-419, 2002

• DOI för Activation of Ribokinase by Monovalent Cations

Primary sequence determinants responsible for site-selective dephosphorylation of the PDGF beta-receptor by the receptor-like protein tyrosine phosphatase DEP-1

Persson, Camilla; Engström, Ulla; Mowbray, Sherry; Östman, Arne

Ingår i FEBS Letters, s. 27-31, 2002

• DOI för Primary sequence determinants responsible for site-selective dephosphorylation of the PDGF beta-receptor by the receptor-like protein tyrosine phosphatase DEP-1

Hinge-bending motion of D-allose-binding protein from Escherichia coli

Magnusson, Ulrika; Chaudhuri, Barnali Neel; Ko, Junsang; Park, Chankyu et al.

Ingår i J Biol Chem, s. 14077-84, 2002

Structure of Aspergillus niger epoxide hydrolase at 1.8A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolyases

Zou, J; Hallberg, BM; Bergfors, T; Oesch, F et al.

Ingår i Structure, s. 111-122, 2000

Induced fit on sugar binding activates ribokinase

Sigrell, JA; Cameron, AD; Mowbray, SL

Ingår i JOURNAL OF MOLECULAR BIOLOGY, s. 1009-1018, 1999

Structure of D-allose binding protein from Escherichia coli bound to D-allose at 1.8 angstrom resolution

Chaudhuri, B.N.; Ko, J; Park, C; Jones, T.A. et al.

Ingår i JOURNAL OF MOLECULAR BIOLOGY, s. 1519-1531, 1999

Conformational changes of ribose-binding protein and two related repressors are tailored to fit the functional need

Mowbray, SL; Bjorkman, AJ

Ingår i JOURNAL OF MOLECULAR BIOLOGY, s. 487-499, 1999

Errors and reproducibility in electron-density map interpretation

Mowbray, SL; Helgstrand, C; Sigrell, JA; Cameron, AD et al.

Ingår i ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, s. 1309-1319, 1999

Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 angstrom resolution: insights into a new family of kinase structures

Sigrell, JA; Cameron, AD; Jones, TA; Mowbray, SL

Ingår i STRUCTURE, s. 183-193, 1998

Purification, characterization, and crystallization of Escherichia coli ribokinase

Sigrell, JA; Cameron, AD; Jones, TA; Mowbray, SL

Ingår i PROTEIN SCIENCE, s. 2474-2476, 1997

Conformational changes of three periplasmic receptors for bacterial chemotaxis and transport: The maltose-, glucose/galactose- and ribose-binding proteins.

Shilton, BH; Flocco, MM; Nilsson, M; Mowbray, SL

Ingår i JOURNAL OF MOLECULAR BIOLOGY, s. 350-363, 1996

Sugar Recognition by a Glucose/Galactose Receptor: Evaluation of Binding Energetics from Molecular Dynamics Simulations

Åqvist, Johan; Mowbray, Sherry L.

Ingår i Journal of Biological Chemistry, s. 9978-9981, 1995

• DOI för Sugar Recognition by a Glucose/Galactose Receptor: Evaluation of Binding Energetics from Molecular Dynamics Simulations

STRANGE BEDFELLOWS - INTERACTIONS BETWEEN ACIDIC SIDE-CHAINS IN PROTEINS

FLOCCO, MM; MOWBRAY, SL

Ingår i JOURNAL OF MOLECULAR BIOLOGY, s. 96-105, 1995

C-ALPHA-BASED TORSION ANGLES - A SIMPLE TOOL TO ANALYZE PROTEIN CONFORMATIONAL-CHANGES

FLOCCO, MM; MOWBRAY, SL

Ingår i PROTEIN SCIENCE, s. 2118-2122, 1995

Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis

Mowbray, Sherry L; Kathiravan, Muthu K; Pandey, Abhishek A; Odell, Luke R

Ingår i Molecules, s. 13161-13176, 2014

• DOI för Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis
• Ladda ner fulltext (pdf) av Inhibition of Glutamine Synthetase: A Potential Drug Target in Mycobacterium tuberculosis

Directed Evolution of an Enantioselective Epoxide Hydrolase: Uncovering the Source of Enantioselectivity at Each Evolutionary Stage

Reetz, Manfred T.; Bocola, Marco; Wang, Li-Wen; Sanchis, Joaquin et al.

Ingår i Journal of the American Chemical Society, s. 7334-7343, 2009

• DOI för Directed Evolution of an Enantioselective Epoxide Hydrolase: Uncovering the Source of Enantioselectivity at Each Evolutionary Stage
• Ladda ner fulltext (pdf) av Directed Evolution of an Enantioselective Epoxide Hydrolase: Uncovering the Source of Enantioselectivity at Each Evolutionary Stage

Specificity and Activity of Escherichia coli Ribokinase

Andersson, C. Evalena; Simon, Jill A.; Cameron, Alexander D.; Mowbray, Sherry L.

Specificity and Activity of Escherichia coli Ribokinase

Andersson, C. Evalena; Simon, Jill A.; Cameron, Alexander D.; Mowbray, Sherry L.

Ribose-5-phosphate isomerase B from Escerichia coli is also a functional allose-6-phosphate isomerase while the Mycobacterium tuberculosis enzyme is not

Roos, Annette K.; Mariano, Sandrine; Kowalinski, Eva; Salmon, Laurent et al.

X-ray structures of the leucine-binding protein illustrate conformational changes, as well as ligand specificity

Magnusson, Ulrika; Luck, Linda A.; Mowbray, Sherry L.

Structure and biochemical function studies of Mycobacterium tuberculosis essential protein Rv3778c

Suarez Covarrubias, Adrian; Larsson, Anna M.; Bergfors, Terese; Jones, T. Alwyn et al.

The 3'-DNA phosphatase AtZDP is present in a high molecular weight protein complex, able to repair gapped DNA with a 3' phosphate group

Valsecchi, Isabel; Wernersson, Jonny; Ubhayasekera, Wimal; Jemth, Per et al.

MEPicides: α,β-Unsaturated Fosmidomycin N-acyl Analogsas inhibitors that selectively target DXR from Plasmodium falciparum, the deadliest causative parasite of human Malaria

Lu, Lu; Wang, Xu; Edwards, Rachel L.; Sooriyaarachchi, Sanjeewani et al.

Chemotaxis receptors: A progress report on structure and function

Mowbray, SL; Sandgren, MOJ

Ingår i JOURNAL OF STRUCTURAL BIOLOGY, s. 257-275, 1998