Mats Larhed

Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran, Esther et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells
• Ladda ner fulltext (pdf) av Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Ingår i European Journal of Medicinal Chemistry Reports, 2024

• DOI för Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
• Ladda ner fulltext (pdf) av Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Ingår i European Journal of Medicinal Chemistry, 2024

• DOI för N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Ladda ner fulltext (pdf) av N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

Gising, Johan; Honarnejad, Saman; Bras, Maaike; Baillie, Gemma L. et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
• Ladda ner fulltext (pdf) av The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Zelleroth, Sofia; Stam, Frida; Nylander, Erik; Ellinor, Kjellgren et al.

Ingår i Hormones and Behavior, 2024

• DOI för The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat
• Ladda ner fulltext (pdf) av The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Engen, Karin; Lundbäck, Thomas; Yadav, Anubha; Puthiyaparambath, Sharathna et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation
• Ladda ner fulltext (pdf) av Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

Gopalan, Greeshma; Palo-Nieto, Carlos; Petersen, Nadia N.; Hallberg, Mathias et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022

• DOI för Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds
• Ladda ner fulltext (pdf) av Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Roy, Tamal; Petersen, Nadia N.; Gopalan, Greeshma; Gising, Johan et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022

• DOI för 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands
• Ladda ner fulltext (pdf) av 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2021

• DOI för N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Hallberg, Mathias; Larhed, Mats

Ingår i Frontiers in Pharmacology, 2020

• DOI för From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase
• Ladda ner fulltext (pdf) av From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction

Adeyemi, Ahmed; Odell, Luke R.; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 7648-7657, 2020

• DOI för Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

Ingår i ChemistryOpen, s. 325-337, 2020

• DOI för Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors
• Ladda ner fulltext (pdf) av Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Ingår i ChemistryOpen, s. 114-125, 2019

• DOI för A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
• Ladda ner fulltext (pdf) av A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki-Heck Coupling of Aryl Iodides

Adeyemi, Ahmed; Wetzel, Alexander; Bergman, Joakim; Brånalt, Jonas et al.

Ingår i Synlett, s. 82-88, 2019

• DOI för Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki-Heck Coupling of Aryl Iodides

Palladium-Catalyzed Molybdenum Hexacarbonyl-Mediated Gas-Free Carbonylative Reactions

Åkerbladh, Linda; Odell, Luke R.; Larhed, Mats

Ingår i Synlett, s. 141-155, 2019

• DOI för Palladium-Catalyzed Molybdenum Hexacarbonyl-Mediated Gas-Free Carbonylative Reactions

Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction

Roy, Tamal; Brandt, Peter; Wetzel, Alexander; Bergman, Joakim et al.

Ingår i Organic Letters, s. 2738-2741, 2017

• DOI för Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction

Non-peptide AT2-receptor agonists

Larhed, Mats; Hallberg, Mathias; Hallberg, Anders

Ingår i Medicinal Chemistry Reviews, 2016

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

Engen, Karin; Rosenström, Ulrika; Axelsson, Hanna; Konda, Vivek et al.

Ingår i Assay and drug development technologies, s. 180-193, 2016

• DOI för Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

Synthesis of 4-Quinolones via a Carbonylative Sonogashira Cross-Coupling Using Molybdenum Hexacarbonyl as a CO Source

Åkerbladh, Linda; Nordeman, Patrik; Wejdemar, Matyas; Odell, Luke R. et al.

Ingår i Journal of Organic Chemistry, s. 1464-1471, 2015

• DOI för Synthesis of 4-Quinolones via a Carbonylative Sonogashira Cross-Coupling Using Molybdenum Hexacarbonyl as a CO Source

Aspartic protease inhibitors containing tertiary alcohol transition-state mimics

Motwani, Hitesh V.; De Rosa, Maria; Odell, Luke R.; Hallberg, Anders et al.

Ingår i European Journal of Medicinal Chemistry, s. 462-490, 2014

• DOI för Aspartic protease inhibitors containing tertiary alcohol transition-state mimics

Synthesis of P1 '-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol

De Rosa, Maria; Unge, Johan; Motwani, Hitesh V.; Rosenquist, Asa et al.

Ingår i Journal of Medicinal Chemistry, s. 6444-6457, 2014

• DOI för Synthesis of P1 '-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol

Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

Wu, Xiongyu; Öhrngren, Per; Joshi, Advait A.; Trejos, Alejandro et al.

Ingår i Journal of Medicinal Chemistry, s. 2724-2736, 2012

• DOI för Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

Evaluation of a Nonresonant Microwave Applicator for Continuous-Flow Chemistry Applications

Öhrngren, Per; Fardost, Ashkan; Russo, Francesco; Fagrell, Magnus et al.

Ingår i Organic Process Research & Development, s. 1053-1063, 2012

• DOI för Evaluation of a Nonresonant Microwave Applicator for Continuous-Flow Chemistry Applications

Aminocarbonylations Employing Mo(CO)(6) and a Bridged Two-Vial System: Allowing the Use of Nitro Group Substituted Aryl Iodides and Aryl Bromides

Nordeman, Patrik; Odell, Luke R; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 11393-11398, 2012

• DOI för Aminocarbonylations Employing Mo(CO)(6) and a Bridged Two-Vial System: Allowing the Use of Nitro Group Substituted Aryl Iodides and Aryl Bromides

Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Gising, Johan; Odell, Luke R.; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2713-2729, 2012

• DOI för Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids

Sköld, Christian; Kleimark, Jonatan; Trejos, Alejandro; Odell, Luke R. et al.

Ingår i Chemistry - A European Journal, s. 4714-4722, 2012

• DOI för Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids
• Ladda ner fulltext (pdf) av Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids

Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran, Esther et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells
• Ladda ner fulltext (pdf) av Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Ingår i European Journal of Medicinal Chemistry Reports, 2024

• DOI för Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
• Ladda ner fulltext (pdf) av Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Ingår i European Journal of Medicinal Chemistry, 2024

• DOI för N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Ladda ner fulltext (pdf) av N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

Gising, Johan; Honarnejad, Saman; Bras, Maaike; Baillie, Gemma L. et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
• Ladda ner fulltext (pdf) av The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Zelleroth, Sofia; Stam, Frida; Nylander, Erik; Ellinor, Kjellgren et al.

Ingår i Hormones and Behavior, 2024

• DOI för The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat
• Ladda ner fulltext (pdf) av The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Stam, Frida; Lind, Sara Florén; Nylander, Erik; Olaniran, Esther et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells
• Ladda ner fulltext (pdf) av Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells

Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

Beveridge, Julia; Söderström, Marcus; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo et al.

Ingår i European Journal of Medicinal Chemistry Reports, 2024

• DOI för Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
• Ladda ner fulltext (pdf) av Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy et al.

Ingår i European Journal of Medicinal Chemistry, 2024

• DOI för N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
• Ladda ner fulltext (pdf) av N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands

The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

Gising, Johan; Honarnejad, Saman; Bras, Maaike; Baillie, Gemma L. et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
• Ladda ner fulltext (pdf) av The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds

The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Zelleroth, Sofia; Stam, Frida; Nylander, Erik; Ellinor, Kjellgren et al.

Ingår i Hormones and Behavior, 2024

• DOI för The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat
• Ladda ner fulltext (pdf) av The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Engen, Karin; Lundbäck, Thomas; Yadav, Anubha; Puthiyaparambath, Sharathna et al.

Ingår i International Journal of Molecular Sciences, 2024

• DOI för Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation
• Ladda ner fulltext (pdf) av Inhibition of Insulin-Regulated Aminopeptidase by Imidazo[1,5-α]pyridines; Synthesis and Evaluation

Two-chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles

Lindman, Jens; Yadav, Anubha; Gising, Johan; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 12978-12985, 2023

• DOI för Two-chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles
• Ladda ner fulltext (pdf) av Two-chamber Aminocarbonylation of Aryl Bromides and Triflates Using Amino Acids as Nucleophiles

Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Stam, Frida; Lind, Sara Florén; Schroff, Anja; Zelleroth, Sofia et al.

Ingår i Current Issues in Molecular Biology, s. 5000-5012, 2022

• DOI för Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures
• Ladda ner fulltext (pdf) av Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

Gopalan, Greeshma; Palo-Nieto, Carlos; Petersen, Nadia N.; Hallberg, Mathias et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022

• DOI för Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds
• Ladda ner fulltext (pdf) av Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Roy, Tamal; Petersen, Nadia N.; Gopalan, Greeshma; Gising, Johan et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022

• DOI för 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands
• Ladda ner fulltext (pdf) av 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Lu, Lu; Åkerbladh, Linda; Ahmad, Shabbir; Konda, Vivek et al.

Ingår i ACS - Infectious Diseases, s. 482-498, 2022

• DOI för Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)
• Ladda ner fulltext (pdf) av Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations

Lindman, Jens; Gopalan, Greeshma; Palo-Nieto, Carlos; Brandt, Peter et al.

Ingår i ACS Omega, 2022

• DOI för Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations
• Ladda ner fulltext (pdf) av Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2021

• DOI för N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Nordeman, Patrik; Jayendra, Z. P.; Briard, E.; Li, Su-Chen et al.

Ingår i European Journal of Pharmaceutical Sciences, 2021

• DOI för ¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Mpakali, Anastasia; Saridakis, Emmanuel; Giastas, Petros; Maben, Zachary et al.

Ingår i ACS Medicinal Chemistry Letters, s. 1429-1434, 2020

• DOI för Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Lundmark, Fanny; Abouzayed, Ayman; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2020

• DOI för Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model
• Ladda ner fulltext (pdf) av Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction

Adeyemi, Ahmed; Odell, Luke R.; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 7648-7657, 2020

• DOI för Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction

Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

Ingår i RSC Medicinal chemistry, s. 234-244, 2020

• DOI för Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

Ingår i ChemistryOpen, s. 325-337, 2020

• DOI för Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors
• Ladda ner fulltext (pdf) av Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

Ingår i European Journal of Pharmacology, 2020

• DOI för Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages
• Ladda ner fulltext (pdf) av Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2019

• DOI för Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer
• Ladda ner fulltext (pdf) av Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Ingår i ChemistryOpen, s. 114-125, 2019

• DOI för A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
• Ladda ner fulltext (pdf) av A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Nuclear Medicine and Biology, s. 1-10, 2019

• DOI för Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass
• Ladda ner fulltext (pdf) av Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

Ingår i Cancers, 2019

• DOI för Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer
• Ladda ner fulltext (pdf) av Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki-Heck Coupling of Aryl Iodides

Adeyemi, Ahmed; Wetzel, Alexander; Bergman, Joakim; Brånalt, Jonas et al.

Ingår i Synlett, s. 82-88, 2019

• DOI för Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki-Heck Coupling of Aryl Iodides

Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Mitran, Bogdan; Rinne, Sara S.; Konijnenberg, Mark W.; Maina, Theodosia et al.

Ingår i International Journal of Cancer, s. 3347-3358, 2019

• DOI för Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26
• Ladda ner fulltext (pdf) av Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

Palladium-Catalyzed Molybdenum Hexacarbonyl-Mediated Gas-Free Carbonylative Reactions

Åkerbladh, Linda; Odell, Luke R.; Larhed, Mats

Ingår i Synlett, s. 141-155, 2019

• DOI för Palladium-Catalyzed Molybdenum Hexacarbonyl-Mediated Gas-Free Carbonylative Reactions

Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

Reddy Vanga, Sudarsana; Sävmarker, Jonas; Ng, Leelee; Larhed, Mats et al.

Ingår i ACS Omega, s. 4509-4521, 2018

• DOI för Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides
• Ladda ner fulltext (pdf) av Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

Wannberg, Johan; Isaksson, Rebecka; Bremberg, Ulf; Backlund, Maria et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 519-522, 2018

• DOI för A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation

Bergman, Sara; Brandt, Peter; Nordeman, Patrik; Larhed, Mats et al.

Ingår i Molecules, 2017

• DOI för Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation
• Ladda ner fulltext (pdf) av Synthesis of ¹¹C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation

Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide

Åkerbladh, Linda; Chow, Shiao Y.; Odell, Luke R.; Larhed, Mats

Ingår i ChemistryOpen, s. 620-628, 2017

• DOI för Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide
• Ladda ner fulltext (pdf) av Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide

Lignin depolymerization to monophenolic compounds in a flow-through system

Kumaniaev, Ivan; Subbotina, Elena; Sävmarker, Jonas; Larhed, Mats et al.

Ingår i Green Chemistry, s. 5767-5771, 2017

• DOI för Lignin depolymerization to monophenolic compounds in a flow-through system

Continuous Flow Synthesis under High-Temperature/High-Pressure Conditions Using a Resistively Heated Flow Reactor

Adeyemi, Ahmed; Bergman, Joakim; Branalt, Jonas; Sävmarker, Jonas et al.

Ingår i Organic Process Research & Development, s. 947-955, 2017

• DOI för Continuous Flow Synthesis under High-Temperature/High-Pressure Conditions Using a Resistively Heated Flow Reactor

High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26

Mitran, Bogdan; Thisgaard, Helge; Rosenström, Ulrika; Dam, Johan Hygum et al.

Ingår i Contrast Media & Molecular Imaging, 2017

• DOI för High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26
• Ladda ner fulltext (pdf) av High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26

Synthesis and In Vitro Evaluation of 5-Substituted Benzovesamicol Analogs containing N-Substituted Amides as Potential Positron Emission Tomography Tracers for the Vesicular Acetylcholine Transporter

Roslin, Sara; De Rosa, Maria; Deuther-Conrad, Winnie; Eriksson, Jonas et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5095-5106, 2017

• DOI för Synthesis and In Vitro Evaluation of 5-Substituted Benzovesamicol Analogs containing N-Substituted Amides as Potential Positron Emission Tomography Tracers for the Vesicular Acetylcholine Transporter

Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines

Åkerbladh, Linda; Schembri, Luke S; Larhed, Mats; Odell, Luke R.

Ingår i Journal of Organic Chemistry, s. 12520-12529, 2017

• DOI för Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines

Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki-Heck Reactions.

Wetzel, Alexander; Bergman, Joakim; Brandt, Peter; Larhed, Mats et al.

Ingår i Organic Letters, s. 1602-1605, 2017

• DOI för Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki-Heck Reactions.

Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation

Rydfjord, Jonas; Skillinghaug, Bobo; Brandt, Peter; Odell, Luke R. et al.

Ingår i Organic Letters, s. 4066-4069, 2017

• DOI för Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation

Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction

Roy, Tamal; Brandt, Peter; Wetzel, Alexander; Bergman, Joakim et al.

Ingår i Organic Letters, s. 2738-2741, 2017

• DOI för Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction

Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Diwakarla, Shanti; Nylander, Erik; Grönbladh, Alfhild; Reddy Vanga, Sudarsana et al.

Ingår i Molecular Pharmacology, s. 413-424, 2016

• DOI för Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Synthesis of C-11-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [C-11]CO

Stevens, Marc Y.; Chow, Shiao Y.; Estrada, Sergio; Eriksson, Jonas et al.

Ingår i ChemistryOpen, s. 566-573, 2016

• DOI för Synthesis of C-11-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [C-11]CO
• Ladda ner fulltext (pdf) av Synthesis of C-11-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [C-11]CO

Synthesis of ¹¹C-labelled Sulfonyl Carbamates via a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols and [¹¹C]CO

Stevens, Marc; Chow, Chow; Estrada, Sergio; Eriksson, Jonas et al.

Ingår i ChemistryOpen, s. 566-573, 2016

• DOI för Synthesis of ¹¹C-labelled Sulfonyl Carbamates via a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols and [¹¹C]CO
• Ladda ner fulltext (pdf) av Synthesis of ¹¹C-labelled Sulfonyl Carbamates via a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols and [¹¹C]CO

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

Diwakarla, Shanti; Nylander, Erik; Grönbladh, Alfhild; Vanga, Sudarsana Reddy et al.

Ingår i ACS Chemical Neuroscience, s. 1383-1392, 2016

• DOI för Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

Mitran, Bogdan; Varasteh, Zohreh; Selvaraju, Ram Kumar; Lindeberg, Gunnar et al.

Ingår i International journal of oncology, s. 2124-2134, 2016

• DOI för Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

Engen, Karin; Rosenström, Ulrika; Axelsson, Hanna; Konda, Vivek et al.

Ingår i Assay and drug development technologies, s. 180-193, 2016

• DOI för Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

Rapid and straightforward transesterification of sulfonyl carbamates

Isaksson, Rebecka; Kumpina, Ilze; Larhed, Mats; Wannberg, Johan

Ingår i Tetrahedron Letters, s. 1476-1478, 2016

• DOI för Rapid and straightforward transesterification of sulfonyl carbamates

Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions

Kumpina, Ilze; Isaksson, Rebecka; Sävmarker, Jonas; Wannberg, Johan et al.

Ingår i Organic Process Research & Development, s. 440-445, 2016

• DOI för Microwave Promoted Transcarbamylation Reaction of Sulfonylcarbamates under Continuous-Flow Conditions

Microwave Heated Continuous Flow Palladium(II)-Catalyzed Desulfitative Synthesis of Aryl Ketones

Skillinghaug, Bobo; Rydfjord, Jonas; Sävmarker, Jonas; Larhed, Mats

Ingår i Organic Process Research & Development, s. 2005-2011, 2016

• DOI för Microwave Heated Continuous Flow Palladium(II)-Catalyzed Desulfitative Synthesis of Aryl Ketones

Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401

Wakchaure, Prasad B.; Bremberg, Ulf; Wannberg, Johan; Larhed, Mats

Ingår i Tetrahedron, s. 6881-6887, 2015

• DOI för Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401

Chemical Conversion of (CO2)-C-11 to (CO)-C-11 via Silacarboxylic Acids: Applications in Palladium-Mediated Carbonylations

Nordeman, Patrik; Friis, Stig D.; Andersen, Thomas L.; Audrain, Helene et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2015

Influence of chelators on targeting properties of In-111 and Ga-68 labeled GRPR antagonist

Orlova, Anna; Varasteh, Zohreh; Mitran, Bogdan; Rosestedt, Maria et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2015

Development of radiocobalt-labeled GRPR antagonist NOTA-PEG2-RM26.

Mitran, Bogdan; Varasteh, Zohreh; Rosenström, Ulrika; Tolmachev, Vladimir et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2015

N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase

Pelcman, Benjamin; Sanin, Andrei; Nilsson, Peter; Schaal, Wesley et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 3017-3023, 2015

• DOI för N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

Pelcman, Benjamin; Sanin, Andrei; Nilsson, Peter; No, Kiyo et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 3024-3029, 2015

• DOI för 3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

The effect of macrocyclic chelators on the targeting properties of the ⁶⁸Ga-labeled gastrin releasing peptide receptor antagonist PEG₂-RM26

Varasteh, Zohreh; Mitran, Bogdan; Rosenström, Ulrika; Velikyan, Irina et al.

Ingår i Nuclear Medicine and Biology, s. 446-454, 2015

• DOI för The effect of macrocyclic chelators on the targeting properties of the ⁶⁸Ga-labeled gastrin releasing peptide receptor antagonist PEG₂-RM26

Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates

Svensson, Fredrik; Engen, Karin; Lundbäck, Thomas; Larhed, Mats et al.

Ingår i Journal of Chemical Information and Modeling, s. 1984-1993, 2015

• DOI för Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates

Rapid and Efficient Conversion of (CO2)-C-11 to (CO)-C-11 through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations

Nordeman, Patrik; Friis, Stig D.; Andersen, Thomas L.; Audrain, Helene et al.

Ingår i Chemistry - A European Journal, s. 17601-17604, 2015

• DOI för Rapid and Efficient Conversion of (CO2)-C-11 to (CO)-C-11 through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations

Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Russo, Francesco; Gising, Johan; Åkerbladh, Linda; Roos, Annette K. et al.

Ingår i ChemistryOpen, s. 342-362, 2015

• DOI för Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents
• Ladda ner fulltext (pdf) av Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity

Strand, Joanna; Nordeman, Patrik; Honarvar, Hadis; Altai, Mohamed et al.

Ingår i ChemistryOpen, s. 174-182, 2015

• DOI för Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity
• Ladda ner fulltext (pdf) av Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity

Synthesis of 4-Quinolones via a Carbonylative Sonogashira Cross-Coupling Using Molybdenum Hexacarbonyl as a CO Source

Åkerbladh, Linda; Nordeman, Patrik; Wejdemar, Matyas; Odell, Luke R. et al.

Ingår i Journal of Organic Chemistry, s. 1464-1471, 2015

• DOI för Synthesis of 4-Quinolones via a Carbonylative Sonogashira Cross-Coupling Using Molybdenum Hexacarbonyl as a CO Source

Palladium-Catalyzed Carbonylation of Aryl Iodides with Sulfinamides

Belfrage, Anna Karin; Wakchaure, Prasad; Larhed, Mats; Sandström, Anja

Ingår i European Journal of Organic Chemistry, s. 7069-7074, 2015

• DOI för Palladium-Catalyzed Carbonylation of Aryl Iodides with Sulfinamides

The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a Ga-68-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin

Varasteh, Zohreh; Rosenström, Ulrika; Velikyan, Irina; Mitran, Bogdan et al.

Ingår i Molecules, s. 10455-10472, 2014

• DOI för The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a Ga-68-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin
• Ladda ner fulltext (pdf) av The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a Ga-68-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin

Continuous flow chemistry with a non-resonant microwave applicator

Rydfjord, Jonas; Sävmarker, Jonas; Konda, Vivek; Skillinghaug, Bobo et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2014

Palladium(II) catalyzed desulfitative coupling reactions of sodium aryl sulfinates and nitriles: Scope, limitations, and mechanistic studies

Skillinghaug, Bobo; Sköld, Christian; Behrends, Malte; Sävmarker, Jonas et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2014

Continuous flow chemistry utilizing silicon carbide (SiC) reactors

Konda, Vivekananda R.; Veron, Jean-Baptiste; Larhed, Mats

Ingår i Abstracts of Papers of the American Chemical Society, 2014

Nonresonant microwave heated continuous flow synthesis in medicinal chemistry

Engen, Karin; Sävmarker, Jonas; Lundback, Thomas; Wannberg, Johan et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2014

Synthesis and evaluation of isoleucine derived angiotensin II AT(2) receptor ligands

Veron, Jean-Baptiste; Joshi, Advait; Wallinder, Charlotta; Larhed, Mats et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 476-479, 2014

• DOI för Synthesis and evaluation of isoleucine derived angiotensin II AT(2) receptor ligands

Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Engen, Karin; Sävmarker, Jonas; Rosenström, Ulrika; Wannberg, Johan et al.

Ingår i Organic Process Research & Development, s. 1582-1588, 2014

• DOI för Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Gising, Johan; Belfrage, Anna Karin; Alogheli, Hiba; Ehrenberg, Angelica et al.

Ingår i Journal of Medicinal Chemistry, s. 1790-1801, 2014

• DOI för Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

Borhade, Sanjay R; Rosenström, Ulrika; Sävmarker, Jonas; Lundbäck, Thomas et al.

Ingår i ChemistryOpen, s. 256-263, 2014

• DOI för Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

Safe Palladium-Catalyzed Cross-Couplings with Microwave Heating Using Continuous-Flow Silicon Carbide Reactors

Konda, Vivek; Rydfjord, Jonas; Sävmarker, Jonas; Larhed, Mats

Ingår i Organic Process Research & Development, s. 1413-1418, 2014

• DOI för Safe Palladium-Catalyzed Cross-Couplings with Microwave Heating Using Continuous-Flow Silicon Carbide Reactors

Synthesis of P1 '-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol

De Rosa, Maria; Unge, Johan; Motwani, Hitesh V.; Rosenquist, Asa et al.

Ingår i Journal of Medicinal Chemistry, s. 6444-6457, 2014

• DOI för Synthesis of P1 '-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol

Synthesis and Labelling of a Piperazine-Based Library of ¹¹C-Labeled Ligands for Imaging of the Vesicular Acetylcholine Transporter

Bergman, Sara; Estrada, Sergio; Hall, Håkan; Rahman, Rashidur et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 525-532, 2014

• DOI för Synthesis and Labelling of a Piperazine-Based Library of ¹¹C-Labeled Ligands for Imaging of the Vesicular Acetylcholine Transporter

N-Aryl Isoleucine Derivatives as Angiotensin II AT(2) Receptor Ligands

Behrends, Malte; Wallinder, Charlotta; Wieckowska, Anna; Guimond, Marie-Odile et al.

Ingår i ChemistryOpen, s. 65-75, 2014

• DOI för N-Aryl Isoleucine Derivatives as Angiotensin II AT(2) Receptor Ligands
• Ladda ner fulltext (pdf) av N-Aryl Isoleucine Derivatives as Angiotensin II AT(2) Receptor Ligands

11C-Labeling of a Potent Hydroxyethylamine BACE-1 Inhibitor and Evaluation in vitro and in vivo

Nordeman, Patrik; Estrada, Sergio; Odell, Luke R; Larhed, Mats et al.

Ingår i Nuclear Medicine and Biology, s. 536-543, 2014

• DOI för 11C-Labeling of a Potent Hydroxyethylamine BACE-1 Inhibitor and Evaluation in vitro and in vivo

C-11-Labeling of a potent hydroxyethylamine BACE-1 inhibitor and evaluation in vitro and in vivo

Nordeman, Patrik; Estrada, Sergio; Odell, Luke; Larhed, Mats et al.

Ingår i Nuclear Medicine and Biology, s. 536-543, 2014

• DOI för C-11-Labeling of a potent hydroxyethylamine BACE-1 inhibitor and evaluation in vitro and in vivo

An Improved Palladium(II)-Catalyzed Method for the Synthesis of Aryl Ketones from Aryl Carboxylic Acids and Organonitriles

Axelsson, Linda; Veron, Jean-Baptiste; Sävmarker, Jonas; Lindh, Jonas et al.

Ingår i Tetrahedron Letters, s. 2376-2380, 2014

• DOI för An Improved Palladium(II)-Catalyzed Method for the Synthesis of Aryl Ketones from Aryl Carboxylic Acids and Organonitriles

Palladium(II)-Catalyzed Desulfitative Synthesis of Aryl Ketones from Sodium Arylsulfinates and Nitriles: Scope, Limitations, and Mechanistic Studies

Skillinghaug, Bobo; Sköld, Christian; Rydfjord, Jonas; Svensson, Fredrik et al.

Ingår i Journal of Organic Chemistry, s. 12018-12032, 2014

• DOI för Palladium(II)-Catalyzed Desulfitative Synthesis of Aryl Ketones from Sodium Arylsulfinates and Nitriles: Scope, Limitations, and Mechanistic Studies

Palladium(II)-Catalyzed Decarboxylative Heck Arylations of Acyclic Electron-Rich Olefins with Internal Selectivity

Fardost, Ashkan; Lindh, Jonas; Sjöberg, Per J. R.; Larhed, Mats

Ingår i Advanced Synthesis and Catalysis, s. 870-878, 2014

• DOI för Palladium(II)-Catalyzed Decarboxylative Heck Arylations of Acyclic Electron-Rich Olefins with Internal Selectivity

Influence of chelators on biodistribution and targeting properties of GRPR antagonist

Mitran, Bogdan; Varasteh, Zohreh; Rosestedt, Maria; Velikyan, Irina et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2014

Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

Tehler, Ulrika; Fagerberg, Jonas H.; Svensson, Richard; Larhed, Mats et al.

Ingår i Journal of Medicinal Chemistry, s. 2690-2694, 2013

• DOI för Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

Palladium-Catalyzed Carbonylative Synthesis of N-Cyanobenzamides from Aryl Iodides/Bromides and Cyanamide

Mane, Rajendra S; Nordeman, Patrik; Odell, Luke R; Larhed, Mats

Ingår i Tetrahedron Letters, s. 6912-6915, 2013

• DOI för Palladium-Catalyzed Carbonylative Synthesis of N-Cyanobenzamides from Aryl Iodides/Bromides and Cyanamide

In Vitro and In Vivo Evaluation of a F-18-Labeled High Affinity NOTA Conjugated Bombesin Antagonist as a PET Ligand for GRPR-Targeted Tumor Imaging

Varasteh, Zohreh; Åberg, Ola; Velikyan, Irina; Lindeberg, Gunnar et al.

Ingår i PLOS ONE, 2013

• DOI för In Vitro and In Vivo Evaluation of a F-18-Labeled High Affinity NOTA Conjugated Bombesin Antagonist as a PET Ligand for GRPR-Targeted Tumor Imaging
• Ladda ner fulltext (pdf) av In Vitro and In Vivo Evaluation of a F-18-Labeled High Affinity NOTA Conjugated Bombesin Antagonist as a PET Ligand for GRPR-Targeted Tumor Imaging

Aminocarbonylation of 4-Iodo-1H-imidazoles with an Amino Acid Amide Nucleophile: Synthesis of Constrained H-Phe-Phe-NH2 Analogues

Skogh, Anna; Fransson, Rebecca; Sköld, Christian; Larhed, Mats et al.

Ingår i Journal of Organic Chemistry, s. 12251-12256, 2013

• DOI för Aminocarbonylation of 4-Iodo-1H-imidazoles with an Amino Acid Amide Nucleophile: Synthesis of Constrained H-Phe-Phe-NH2 Analogues

GRPR antagonist NOTA-P2-RM26 labeled with fluorine-18: radiochemistry, in vitro and in vivo evaluation

Varasteh, Zohreh; Åberg, Ola; Lindberg, G.; Antoni, Gunnar et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2013

Design and Synthesis of P1-P3 Macrocyclic Tertiary-Alcohol-Comprising HIV-1 Protease Inhibitors

Joshi, Advait; Véron, Jean-Baptiste; Unge, Johan; Rosenquist, Asa et al.

Ingår i Journal of Medicinal Chemistry, s. 8999-9007, 2013

• DOI för Design and Synthesis of P1-P3 Macrocyclic Tertiary-Alcohol-Comprising HIV-1 Protease Inhibitors

Temperature measurements with two different IR sensors in a continuous-flow microwave heated system

Rydfjord, Jonas; Svensson, Fredrik; Fagrell, Magnus; Sävmarker, Jonas et al.

Ingår i Beilstein Journal of Organic Chemistry, s. 2079-2087, 2013

• DOI för Temperature measurements with two different IR sensors in a continuous-flow microwave heated system

Decarboxylative Palladium(II)-Catalyzed Synthesis of Aryl Amidines from Aryl Carboxylic Acids: Development and Mechanistic Investigation

Rydfjord, Jonas; Svensson, Fredrik; Trejos, Alejandro; Sjöberg, Per J. R. et al.

Ingår i Chemistry - A European Journal, s. 13803-13810, 2013

• DOI för Decarboxylative Palladium(II)-Catalyzed Synthesis of Aryl Amidines from Aryl Carboxylic Acids: Development and Mechanistic Investigation

Synthesis and Characterization of a High-Affinity NOTA-Conjugated Bombesin Antagonist for GRPR-Targeted Tumor Imaging

Varasteh, Zohreh; Velikyan, Irina; Lindeberg, Gunnar; Sörensen, Jens et al.

Ingår i Bioconjugate chemistry, s. 1144-1153, 2013

• DOI för Synthesis and Characterization of a High-Affinity NOTA-Conjugated Bombesin Antagonist for GRPR-Targeted Tumor Imaging
• Ladda ner fulltext (pdf) av Synthesis and Characterization of a High-Affinity NOTA-Conjugated Bombesin Antagonist for GRPR-Targeted Tumor Imaging

One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates

Wannberg, Johan; Wallinder, Charlotta; Unlusoy, Meltem; Sköld, Christian et al.

Ingår i Journal of Organic Chemistry, s. 4184-4189, 2013

• DOI för One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates

(AlF)-F-18-labelling of NOTA-P2-RM26 and its evaluation as a PET ligand for GRPR/BB2

Åberg, Ola; Varasteh, Zohreh; Lindeberg, Gunnar; Larhed, Mats et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2013

Synthesis and biological evaluation of a piperazine-based library of C-11-Labeled PET tracers for imaging of the vesicular acetylcholine transporter

Bergman, Sara; Blomgren, Andreas; Hall, Håkan; Larhed, Mats et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, 2013

DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues

Jansson, Anna; Więckowska, Anna; Björkelid, Christofer; Yahiaoui, Samir et al.

Ingår i Journal of Medicinal Chemistry, s. 6190-6199, 2013

• DOI för DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues
• Ladda ner fulltext (pdf) av DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues

Theoretical and Experimental Investigation of Palladium(II)-Catalyzed Decarboxylative Addition of Arenecarboxylic Acid to Nitrile

Svensson, Fredrik; Mane, Rajendra S.; Sävmarker, Jonas; Larhed, Mats et al.

Ingår i Organometallics, s. 490-497, 2013

• DOI för Theoretical and Experimental Investigation of Palladium(II)-Catalyzed Decarboxylative Addition of Arenecarboxylic Acid to Nitrile

Synthesis of antimalarial compounds fosmidomycin and FR900098 through N- or P-alkylation reactions

Suresh, Surisetti; Shyamraj, Dharavath; Larhed, Mats

Ingår i Tetrahedron, s. 1183-1188, 2013

• DOI för Synthesis of antimalarial compounds fosmidomycin and FR900098 through N- or P-alkylation reactions

Diarylated Ethanones from Mo(CO)(6)-Mediated and Microwave-Assisted Palladium-Catalysed Carbonylative Negishi Cross-Couplings

Motwani, Hitesh V.; Larhed, Mats

Ingår i European Journal of Organic Chemistry, s. 4729-4733, 2013

• DOI för Diarylated Ethanones from Mo(CO)(6)-Mediated and Microwave-Assisted Palladium-Catalysed Carbonylative Negishi Cross-Couplings

Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

Wu, Xiongyu; Öhrngren, Per; Joshi, Advait A.; Trejos, Alejandro et al.

Ingår i Journal of Medicinal Chemistry, s. 2724-2736, 2012

• DOI för Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

Evaluation of a Nonresonant Microwave Applicator for Continuous-Flow Chemistry Applications

Öhrngren, Per; Fardost, Ashkan; Russo, Francesco; Fagrell, Magnus et al.

Ingår i Organic Process Research & Development, s. 1053-1063, 2012

• DOI för Evaluation of a Nonresonant Microwave Applicator for Continuous-Flow Chemistry Applications

Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Nordqvist, Anneli; Nilsson, Mikael T.; Lagerlund, Olof; Muthas, Daniel et al.

Ingår i MedChemComm, s. 620-626, 2012

• DOI för Synthesis, biological evaluation and X-ray crystallographic studies of imidazo[1,2-a]-pyridine based Mycobacterium tuberculosis glutamine synthetase inhibitors

Molybdenum Hexacarbonyl Mediated CO Gas-Free Carbonylative Reactions

Odell, Luke R.; Russo, Francesco; Larhed, Mats

Ingår i Synlett, s. 685-698, 2012

• DOI för Molybdenum Hexacarbonyl Mediated CO Gas-Free Carbonylative Reactions

Aminocarbonylations Employing Mo(CO)(6) and a Bridged Two-Vial System: Allowing the Use of Nitro Group Substituted Aryl Iodides and Aryl Bromides

Nordeman, Patrik; Odell, Luke R; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 11393-11398, 2012

• DOI för Aminocarbonylations Employing Mo(CO)(6) and a Bridged Two-Vial System: Allowing the Use of Nitro Group Substituted Aryl Iodides and Aryl Bromides

Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

Sävmarker, Jonas; Rydfjord, Jonas; Gising, Johan; Odell, Luke R. et al.

Ingår i Organic Letters, s. 2394-2397, 2012

• DOI för Direct Palladium(II)-Catalyzed Synthesis of Arylamidines from Aryltrifluoroborates

Oxidative Heck Reactions Using Aryltrifluoroborates and Aryl N-Methyliminodiacetic Acid (MIDA) Boronates

Sävmarker, Jonas; Lindh, Jonas; Nilsson, Peter; Sjöberg, Per et al.

Ingår i ChemistryOpen, s. 140-146, 2012

• DOI för Oxidative Heck Reactions Using Aryltrifluoroborates and Aryl N-Methyliminodiacetic Acid (MIDA) Boronates

Site-specific radioiodination of HER2-targeting affibody molecules using iodophenetylmaleimide decreases renal uptake of radioactivity

Strand, Joanna; Nordeman, Patrik; Honarvar, Hadis; Altai, Mohamed et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2012

Synthesis and characterization of a high affinity NOTA-conjugated bombesin antagonist for GRPR-targeted tumor imaging

Varasteh, Zohreh; Velikyan, Irina; Lindeberg, Gunnar; Sörensen, Jens et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2012

A non-resonant microwave applicator fully dedicated to continuous flow chemistry

Fardost, Ashkan; Russo, Francesco; Larhed, Mats

Ingår i Chimica oggi, s. 14-16, 2012

Synthesis of functionalized furopyrazines as restricted dipeptidomimetics

Claerhout, Stijn; Sharma, Sweta; Sköld, Christian; Cavaluzzo, Claudia et al.

Ingår i Tetrahedron, s. 3019-3029, 2012

• DOI för Synthesis of functionalized furopyrazines as restricted dipeptidomimetics

Development of Stereocontrolled Palladium(II)-Catalyzed Domino Heck/Suzuki β, α-Diarylation Reactions with Chelating Vinyl Ethers and Arylboronic Acids

Trejos, Alejandro; Odell, Luke R.; Larhed, Mats

Ingår i ChemistryOpen, s. 49-56, 2012

• DOI för Development of Stereocontrolled Palladium(II)-Catalyzed Domino Heck/Suzuki β, α-Diarylation Reactions with Chelating Vinyl Ethers and Arylboronic Acids
• Ladda ner fulltext (pdf) av Development of Stereocontrolled Palladium(II)-Catalyzed Domino Heck/Suzuki β, α-Diarylation Reactions with Chelating Vinyl Ethers and Arylboronic Acids

Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Gising, Johan; Odell, Luke R.; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2713-2729, 2012

• DOI för Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Gising, Johan; Nilsson, Mikael T; Odell, Luke R; Yahiaoui, Samir et al.

Ingår i Journal of Medicinal Chemistry, s. 2894-2898, 2012

• DOI för Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors
• Ladda ner fulltext (pdf) av Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids

Sköld, Christian; Kleimark, Jonatan; Trejos, Alejandro; Odell, Luke R. et al.

Ingår i Chemistry - A European Journal, s. 4714-4722, 2012

• DOI för Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids
• Ladda ner fulltext (pdf) av Transmetallation Versus β-Hydride Elimination: The Role of 1,4 Benzoquinone in Chelation-Controlled Arylation Reactions with Arylboronic Acids

Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase

Andaloussi, Mounir; Henriksson, Lena M.; Wieckowska, Anna; Lindh, Martin et al.

Ingår i Journal of Medicinal Chemistry, s. 4964-4976, 2011

• DOI för Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase
• Ladda ner fulltext (pdf) av Design, Synthesis, and X-ray Crystallographic Studies of alpha-Aryl Substituted Fosmidomycin Analogues as Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase

Microwave-Assisted Palladium(II)-Catalyzed Synthesis of Aryl Ketones from Aryl Sulfinates and Direct ESI-MS Studies Thereof

Behrends, Malte; Sävmarker, Jonas; Sjöberg, Per J. R.; Larhed, Mats

Ingår i ACS Catalysis, s. 1455-1459, 2011

• DOI för Microwave-Assisted Palladium(II)-Catalyzed Synthesis of Aryl Ketones from Aryl Sulfinates and Direct ESI-MS Studies Thereof

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Ingår i Journal of Pharmaceutical Sciences, s. 3763-3772, 2011

• DOI för Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Chelation-Mediated Palladium(II)-Catalyzed Domino Heck-Mizoroki/Suzuki-Miyaura Reactions Using Arylboronic Acids: Increasing Scope and Mechanistic Understanding

Yahiaoui, Samir; Fardost, Ashkan; Trejos, Alejandro; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 2433-2438, 2011

• DOI för Chelation-Mediated Palladium(II)-Catalyzed Domino Heck-Mizoroki/Suzuki-Miyaura Reactions Using Arylboronic Acids: Increasing Scope and Mechanistic Understanding

Hiv-1 Protease Inhibitors with a Tertiary Alcohol Containing a Transition-State Mimic and Various P2/P1´ Substituents

Öhrngren, Per; Wu, Xiongyu; Persson, Magnus; Ekegren, Jenny et al.

Ingår i MedChemComm, s. 701-709, 2011

• DOI för Hiv-1 Protease Inhibitors with a Tertiary Alcohol Containing a Transition-State Mimic and Various P2/P1´ Substituents

Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: An attempt to improve the activity against Mycobacterium tuberculosis

Andaloussi, Mounir; Lindh, Martin; Björkelid, Christofer; Suresh, Surisetti et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 5403-5407, 2011

• DOI för Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: An attempt to improve the activity against Mycobacterium tuberculosis

Investigation of alpha-phenylnorstatine and alpha-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors

Wångsell, Fredrik; Nordeman, Patrik; Sävmarker, Jonas; Emanuelsson, Rikard et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 145-155, 2011

• DOI för Investigation of alpha-phenylnorstatine and alpha-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors

Richard F. Heck: Nobel Laureate in Chemistry

Odell, Luke R; Larhed, Mats

Ingår i Les Prix Nobel, s. 133-138, 2011

Non-peptide AT2-receptor agonists

Steckelings, U. Muscha; Larhed, Mats; Hallberg, Anders; Widdop, Robert E. et al.

Ingår i Current opinion in pharmacology (Print), s. 187-192, 2011

• DOI för Non-peptide AT2-receptor agonists

Microwave-Assisted Synthesis of Weinreb and MAP Aryl Amides via Pd-Catalyzed Heck Aminocarbonylation Using Mo(CO)(6) or W(CO)(6)

Wieckowska, Anna; Fransson, Rebecca; Odell, Luke R.; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 978-981, 2011

• DOI för Microwave-Assisted Synthesis of Weinreb and MAP Aryl Amides via Pd-Catalyzed Heck Aminocarbonylation Using Mo(CO)(6) or W(CO)(6)

Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors

Nordqvist, Anneli; Björkelid, Christofer; Andaloussi, Mounir; Jansson, Anna M. et al.

Ingår i Journal of Organic Chemistry, s. 8986-8998, 2011

• DOI för Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors
• Ladda ner fulltext (pdf) av Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase Inhibitors

Hepatitis C protease inhibitors based on 2(1H)-pyrazinones

Gising, Johan; Belfrage, Anna Karin; Örtqvist, Pernilla; Larhed, Mats et al.

Ingår i Abstracts of Papers of the American Chemical Society, 2010

Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

Örtqvist, Pernilla; Gising, Johan; Ehrenberg, Angelica; Vema, Aparna et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 6512-6525, 2010

• DOI för Discovery of Achiral Inhibitors of the Hepatitis C Virus NS3 Protease based on 2(1H)-pyrazinones

HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells

Mahalingam, A. Kannan; Axelsson, Linda; Ekegren, Jenny K.; Wannberg, Johan et al.

Ingår i Journal of Medicinal Chemistry, s. 607-615, 2010

• DOI för HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells

Synthesis of a small library of non-symmetric cyclic sulfamide HIV-1 protease inhibitors

Ax, Anna; Joshi, Advait A.; Orrling, Kristina M.; Vrang, Lotta et al.

Ingår i Tetrahedron, s. 4049-4056, 2010

• DOI för Synthesis of a small library of non-symmetric cyclic sulfamide HIV-1 protease inhibitors

Synthesis of aryl ketones by palladium(II)-catalyzed decarboxylative addition of benzoic acids to nitriles

Lindh, Jonas; Sjöberg, Per J. R.; Larhed, Mats

Ingår i Angewandte Chemie International Edition, s. 7733-7737, 2010

• DOI för Synthesis of aryl ketones by palladium(II)-catalyzed decarboxylative addition of benzoic acids to nitriles

Synthesis and evaluation of a ¹¹C-labelled angiotensin II AT₂ receptor ligand

Åberg, Ola; Stevens, Marc; Lindh, Jonas; Wallinder, Charlotta et al.

Ingår i Journal of labelled compounds & radiopharmaceuticals, s. 616-624, 2010

• DOI för Synthesis and evaluation of a ¹¹C-labelled angiotensin II AT₂ receptor ligand

Continuous Flow Palladium(II): Catalyzed Oxidative Heck Reactions with Arylboronic Acids

Odell, Luke R.; Lindh, Jonas; Gustafsson, Tomas; Larhed, Mats

Ingår i European Journal of Organic Chemistry, s. 2270-2274, 2010

• DOI för Continuous Flow Palladium(II): Catalyzed Oxidative Heck Reactions with Arylboronic Acids

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Gising, Johan; Örtqvist, Pernilla; Sandström, Anja; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 2809-2815, 2009

• DOI för A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors

Nilsson, Mikael T.; Krajewski, Wojciech W.; Srinivasa, Bachally R.; Yahiaoui, Samir et al.

Ingår i Journal of Molecular Biology, s. 504-513, 2009

• DOI för Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors
• Ladda ner fulltext (pdf) av Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors

α-Substituted Norstatines as the Transistion-State Mimic in Inhibitors of Multiple Digestive Vacuole Malaria Aspartic Proteases

Orrling, Kristina M.; Marzahn, Melissa; Gutiérrez-de-Terán, Hugo; Åqvist, Johan et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5933-5949, 2009

• DOI för α-Substituted Norstatines as the Transistion-State Mimic in Inhibitors of Multiple Digestive Vacuole Malaria Aspartic Proteases

Palladium(II)-catalyzed coupling reactions with a chelating vinyl ether and arylboronic acids: a new Heck/Suzuki domino diarylation reaction

Trejos, Alejandro; Fardost, Ashkan; Yahiaoui, Samir; Larhed, Mats

Ingår i Chemical Communications, s. 7587-7589, 2009

• DOI för Palladium(II)-catalyzed coupling reactions with a chelating vinyl ether and arylboronic acids: a new Heck/Suzuki domino diarylation reaction

Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Odell, Luke R.; Nilsson, Mikael T.; Gising, Johan; Lagerlund, Olof et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 4790-4793, 2009

• DOI för Functionalized 3-amino-imidazo[1,2-a]pyridines: A novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors

Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic

Wångsell, Fredrik; Russo, Francesco; Sävmarker, Jonas; Rosenqvist, Åsa et al.

Ingår i Bioorganic & Medicinal Chemistry Letters, s. 4711-4714, 2009

• DOI för Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic

Synthesis and evaluation of a new class of tertiary alcohol based BACE-1 inhibitors

Russo, Francesco; Wångsell, Fredrik; Sävmarker, Jonas; Jacobsson, Micael et al.

Ingår i Tetrahedron, s. 10047-10059, 2009

• DOI för Synthesis and evaluation of a new class of tertiary alcohol based BACE-1 inhibitors

Aminocarbonylations of Alkenyl Phosphates, Chlorides, Bromides and Triflates with Mo(CO)₆ as a Solid CO source

Lagerlund, Olof; Mantel, Mette L. H.; Larhed, Mats

Ingår i Tetrahedron, s. 7646-7652, 2009

• DOI för Aminocarbonylations of Alkenyl Phosphates, Chlorides, Bromides and Triflates with Mo(CO)₆ as a Solid CO source

Microwave-assisted palladium(II)-catalyzed Heck reactions

Lindh, Jonas; Larhed, Mats

Ingår i Chimica oggi, s. 11-14, 2009

Synthesis of styrenes by palladium(II)-catalyzed vinylation of arylboronic acids and aryltrifluoroborates by using vinyl acetate

Lindh, Jonas; Sävmarker, Jonas; Nilsson, Peter; Sjöberg, Per J R et al.

Ingår i Chemistry - A European Journal, s. 4630-4636, 2009

• DOI för Synthesis of styrenes by palladium(II)-catalyzed vinylation of arylboronic acids and aryltrifluoroborates by using vinyl acetate

Microwave-promoted palladium(II)-catalyzed C-P bond formation by using arylboronic acids or aryltrifluoroborates.

Andaloussi, Mounir; Lindh, Jonas; Sävmarker, Jonas; Sjöberg, Per J.R. et al.

Ingår i Chemistry - A European Journal, s. 13069-13074, 2009

• DOI för Microwave-promoted palladium(II)-catalyzed C-P bond formation by using arylboronic acids or aryltrifluoroborates.

Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic

Wu, Xiongyu; Ohrngren, Per; Ekegren, Jenny K; Unge, Johan et al.

Ingår i Journal of Medicinal Chemistry, s. 1053-1057, 2008

• DOI för Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic

Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

Nordqvist, Anneli; Nilsson, Mikael T.; Röttger, Svenja; Odell, Luke R. et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5501-5513, 2008

• DOI för Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery
• Ladda ner fulltext (pdf) av Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

Enantiopure 2-Aryl-2-Methyl Cyclopentanones by an Asymmetric Chelation-Controlled Heck Reaction Using Aryl Bromides: Increased Preparative Scope and Effect of Ring Size on Reactivity and Selectivity

Datta, Gopal K.; Nordeman, Patrik; Dackenberg, Jakob; Nilsson, Peter et al.

Ingår i Tetrahedron, s. 1120-1126, 2008

• DOI för Enantiopure 2-Aryl-2-Methyl Cyclopentanones by an Asymmetric Chelation-Controlled Heck Reaction Using Aryl Bromides: Increased Preparative Scope and Effect of Ring Size on Reactivity and Selectivity

Microwave-assisted, Mo(CO)(6)-mediated, palladium-catalyzed amino-carbonylation of aryl halides using allylamine: from exploration to scale-up

Appukkuttan, Prasad; Axelsson, Linda; Van der Eycken, Erik; Larhed, Mats

Ingår i Tetrahedron Letters, s. 5625-5628, 2008

• DOI för Microwave-assisted, Mo(CO)(6)-mediated, palladium-catalyzed amino-carbonylation of aryl halides using allylamine: from exploration to scale-up

Fast, acid-free, and selective lactamization of lactones in ionic liquids

Orrling, Kristina M; Wu, Xiongyu; Russo, Francesco; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 8627-30, 2008

• DOI för Fast, acid-free, and selective lactamization of lactones in ionic liquids

Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors

Pasquini, Serena; Mugnaini, Claudia; Tintori, Cristina; Botta, Maurizio et al.

Ingår i Journal of Medicinal Chemistry, s. 5125-9, 2008

• DOI för Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors

Stereoselective Heck arylation of a functionalized cyclopentenyl ether using (S)-N-methyl-pyrrolidine as the stereochemical controller

Trejos, Alejandro; Sävmarker, Jonas; Schlummer, Stefanie; Datta, Gopal K. et al.

Ingår i Tetrahedron, s. 8746-8751, 2008

• DOI för Stereoselective Heck arylation of a functionalized cyclopentenyl ether using (S)-N-methyl-pyrrolidine as the stereochemical controller

High Stereoselectivity in Chelation-Controlled Intermolecular Heck Reactions with Aryl Chlorides, Vinyl Chlorides and Vinyl Triflates

Datta, Gopal K.; Larhed, Mats

Ingår i Organic and biomolecular chemistry, s. 674-676, 2008

• DOI för High Stereoselectivity in Chelation-Controlled Intermolecular Heck Reactions with Aryl Chlorides, Vinyl Chlorides and Vinyl Triflates

A mechanistic study on modern palladium catalyst precursors as new gateways to Pd(0) in cationic Heck reactions

Svennebring, Andreas; Sjöberg, Per; Larhed, Mats; Nilsson, Peter

Ingår i Tetrahedron, s. 1808-1812, 2008

• DOI för A mechanistic study on modern palladium catalyst precursors as new gateways to Pd(0) in cationic Heck reactions

Microwave-promoted aminocarbonylation of aryl triflates using Mo(CO)(6) as a solid CO source

Odell, Luke R.; Sävmarker, Jonas; Larhed, Mats

Ingår i Tetrahedron Letters, s. 6115-6118, 2008

• DOI för Microwave-promoted aminocarbonylation of aryl triflates using Mo(CO)(6) as a solid CO source

Microwave-accelerated spiro-cyclizations of o-halobenzyl cyclohexenyl ethers by palladium(0) catalysis

Svennebring, Andreas; Nilsson, Peter; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 5851-5854, 2007

• DOI för Microwave-accelerated spiro-cyclizations of o-halobenzyl cyclohexenyl ethers by palladium(0) catalysis

Efficient palladium(II) catalysis under air. Base-free oxidative heck reactions at room temperature or with microwave heating

Lindh, Jonas; Enquist, Per-Anders; Pilotti, Åke; Nilsson, Peter et al.

Ingår i Journal of Organic Chemistry, s. 7957-7962, 2007

• DOI för Efficient palladium(II) catalysis under air. Base-free oxidative heck reactions at room temperature or with microwave heating

Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor

Georgsson, Jennie; Sköld, Christian; Botros, Milad; Lindeberg, Gunnar et al.

Ingår i Journal of Medicinal Chemistry, s. 1711-1715, 2007

• DOI för Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor

Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

Lagerlund, Olof; Odell, Luke R.; Mowbray, Sherry L.; Nilsson, Mikael T. et al.

Ingår i Combinatorial chemistry & high throughput screening, s. 783-789, 2007

• DOI för Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

Highly regioselective internal heck arylation of hydroxyalkyl vinyl ethers by aryl halides in water

Arvela, Riina K.; Pasquini, Serena; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 6390-6396, 2007

• DOI för Highly regioselective internal heck arylation of hydroxyalkyl vinyl ethers by aryl halides in water

Microwave-Enhanced Copper-Catalyzed N-Arylation of Free and Protected Amino Acids in Water

Röttger, Svenja; Sjöberg, Per J. R.; Larhed, Mats

Ingår i Journal of combinatorial chemistry, s. 204-209, 2007

• DOI för Microwave-Enhanced Copper-Catalyzed N-Arylation of Free and Protected Amino Acids in Water

ESI-MS Detection of Proposed Reaction Intermediates in the Air-Promoted and Ligand-Modulated Oxidative Heck Reaction

Enquist, Per-Anders; Nilsson, Peter; Sjöberg, Per; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 8779-8786, 2006

• DOI för ESI-MS Detection of Proposed Reaction Intermediates in the Air-Promoted and Ligand-Modulated Oxidative Heck Reaction

Variations of the P2 Group in HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

Ekegren, Jenny; Gising, Johan; Wallberg, Hans; Larhed, Mats et al.

Ingår i Organic and biomolecular chemistry, s. 3040-3043, 2006

• DOI för Variations of the P2 Group in HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold

Ekegren, Jenny K; Ginman, Nina; Johansson, Åsa; Wallberg, Hans et al.

Ingår i Journal of Medicinal Chemistry, s. 1828-1832, 2006

• DOI för Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold

Stereoselective Synthesis of 3-Aminoindan-1-ones and Subsequent Incorporation into HIV-1 Protease Inhibitors

Arefalk, Anna; Wannberg, Johan; Larhed, Mats; Hallberg, Anders

Ingår i Journal of Organic Chemistry, s. 1265-1268, 2006

A New Structural Theme in C2-Symmetric HIV-1 Protease Inhibitors: ortho-Substituted P1/P1’ Side Chains

Wannberg, Johan; Sabnis, Yogesh A.; Vrang, Lotta; Samuelsson, Bertil et al.

Ingår i Bioorganic & Medicinal Chemistry, s. 5303-5315, 2006

Open-air oxidative Heck reactions at room temperature

Enquist, Per-Anders; Lindh, Jonas; Nilsson, Peter; Larhed, Mats

Ingår i Green Chemistry, s. 338-343, 2006

• DOI för Open-air oxidative Heck reactions at room temperature

Selective Terminal Heck Arylation of Vinyl Ethers with Aryl Chlorides: A Combined Experimental-Computational Approach Including Synthesis of Betaxolol

Datta, Gopal K.; Schenck, Henrik von; Hallberg, Anders; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 3896-3903, 2006

Microwave-Accelerated Synthesis of P1´-Extended HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

Ekegren, Jenny; Ginman, Nina; Johansson, Åsa; Wallberg, Hans et al.

Ingår i Jounal of Medicinal Chemistry, s. 1828-1832, 2006

Microwave-Promoted Aminocarbonylation of Aryl Iodides, Aryl Bromides, and Aryl Chlorides in Water

Wu, Xiongyu; Ekegren, Jenny; Larhed, Mats

Ingår i Organometallics, s. 1434-1439, 2006

Microwave-promoted aminocarbonylation of aryl iodides, aryl bromides and aryl chlorides in water.

Wu, X; Ekegren, J K; Larhed, Mats

Ingår i Organometallics, s. 1434-1832, 2006

Hydroxylamine as an ammonia equivalent in microwave-enhanced aminocarbonylations

Wu, Xiongyu; Wannberg, Johan; Larhed, Mats

Ingår i Tetrahedron, s. 4665-4670, 2006

Microwave-assisted and metal-catalyzed coupling reactions

Nilsson, Peter; Olofsson, K; Larhed, Mats

Ingår i Top. Curr. Chem., s. 103-144, 2006

Microwave-accelerated synthesis of protease inhibitors

Wannberg, Johan; Ersmark, Karolina; Larhed, Mats

Ingår i Top. Curr. Chem., s. 3040-3043, 2006

Fast and selective synthesis of novel cyclic sulfamide HIV-1 purchase inhibitors under controlled microwave heating

Gold, H; Ax, A; Vrang, L; Samuelsson, B et al.

Ingår i Tetrahedron, s. 4671-4675, 2006

Selective terminal heck arylation of vinyl ethers with aryl chlorides: a combined experimental-computational approach including synthesis of betaxolol.

Datta, Gopal K; von Schenck, Henrik; Hallberg, Anders; Larhed, Mats

Ingår i J Org Chem, s. 3896-903, 2006

Microwave Irradiation as a High-Speed Toll for Activation of Sluggish Aryl Chlorides in Grignard Reactions

Gold, Henrik; Larhed, Mats; Nilsson, Peter

Ingår i Synlett, s. 1596-1600, 2005

Microwave-Enhanced and Metal-Catalyzed Functionalizations of the 4-Aryl-Dihydropyrimidone Template

Wannberg, Johan; Dallinger, Doris; Kappe, C. Oliver; Larhed, Mats

Ingår i Journal of combinatorial chemistry, s. 574-583, 2005

Super fast cobalt carbonyl-mediated synthesis of ureas

Enquist, Per-Anders; Nilsson, Peter; Edin, Johan; Larhed, Mats

Ingår i Tetrahedron Letters, s. 3335-3339, 2005

Masked 3-Aminoindan-1-ones by a Palladium-Catalyzed Three-Component Annulation Reaction

Arefalk, Anna; Larhed, Mats; Hallberg, Anders

Ingår i Journal of Organic Chemistry, s. 938-942, 2005

Easy-to-Execute Carbonylations: Microwave Synthesis of Acyl Sulfonamides Using Mo(CO)6 as a Solid Carbon Monoxide Source

Wu, Xiongyu; Rönn, Robert; Gossas, Thomas; Larhed, Mats

Ingår i The Journal of Organic Chemistry, s. 3094-3098, 2005

A One-Pot Isomerization-Arylation of 2,3-Epoxycyclohexanone under Controlled Microwave Heating

Svennebring, Andreas; Garg, Neeraj; Nilsson, Peter; Hallberg, Anders et al.

Ingår i The Journal of Organic Chemistry, s. 4720-4725, 2005

Microwave-enhanced carbonylative generation of indanones and 3-acylaminoindanones.

Wu, Xiongyu; Nilsson, Peter; Larhed, Mats

Ingår i J Org Chem, s. 346-9, 2005

Microwave-enhanced aminocarbonylations in water.

Wu, Xiongyu; Larhed, Mats

Ingår i Org Lett, s. 3327-9, 2005

Super fast cobalt carbonyl-mediated synthesis of ureas compounds

Enquist, Per-Anders; Johan, Edin; Nilsson, Peter; Larhed, Mats

Ingår i Tetrahedron Letters, s. 3335-3339, 2005

Masked 3-aminoindan-1-ones by a palladium-catalyzed three-component annulation reaction.

Arefalk, Anna; Larhed, Mats; Hallberg, Anders

Ingår i J Org Chem, s. 938-42, 2005

A one-pot isomerization-arylation of 2,3-epoxycyclohexanone under controlled microwave heating.

Svennebring, Andreas; Garg, Neeraj; Nilsson, Peter; Hallberg, Anders et al.

Ingår i J Org Chem, s. 4720-5, 2005

Microwave-promoted aminocarbonylations of aryl chlorides using Mo(CO)(6) as a solid carbon monoxide source.

Lagerlund, Olof; Larhed, Mats

Ingår i J Comb Chem, s. 4-6, 2005

All the rave in microwaves.

Kappe, C Oliver; Larhed, Mats

Ingår i Angew Chem Int Ed Engl, s. 7666-9, 2005

Easy-to-execute carbonylations: microwave synthesis of acyl sulfonamides using Mo(CO)(6) as a solid carbon monoxide source.

Wu, Xiongyu; Rönn, Robert; Gossas, Thomas; Larhed, Mats

Ingår i J Org Chem, s. 3094-8, 2005

An efficient method to perform milliliter-scale PCR utilizing highly controlled microwave thermocycling

Orrling, Kristina; Nilsson, Peter; Gullberg, Mats; Larhed, Mats

Ingår i Chemical Communications, s. 790-791, 2004

• DOI för An efficient method to perform milliliter-scale PCR utilizing highly controlled microwave thermocycling

Microwave-Promoted and Chelation-Controlled Double Arylation of Terminal Olefinic Carbon of Vinyl Ethers.

Svennebring, Andreas; Nilsson, Peter; Larhed, Mats

Ingår i The Journal of Organic Chemistry, s. 3345-3349, 2004

Direct Microwave Synthesis of N,N'-diacylhydrazines and Boc-protected Hydrazides by in situ Carbonylations under Air

Herrero, Maria Antonia; Wannberg, Johan; Larhed, Mats

Ingår i Synlett, s. 2335-2338, 2004

Microwave-enhanced medicinal chemistry: a high-speed opportunity for convenient preparation of protease inhibitors.

Ersmark, Karolina; Larhed, Mats; Wannberg, Johan

Ingår i Curr Opin Drug Discov Devel, s. 417-27, 2004

The first ligand-modulated oxidative Heck vinylation. Efficient catalysis with molecular oxygen as palladium(0) oxidant.

Andappan, Murugaiah M S; Nilsson, Peter; Larhed, Mats

Ingår i Chem Commun (Camb), s. 218-9, 2004

Dioxygen-promoted regioselective oxidative heck arylations of electron-rich olefins with arylboronic acids.

Andappan, Murugaiah M S; Nilsson, Peter; von Schenck, Henrik; Larhed, Mats

Ingår i J Org Chem, s. 5212-8, 2004

An efficient method to perform milliliter-scale PCR utilizing highly controlled microwave thermocycling.

Orrling, Kristina; Nilsson, Peter; Gullberg, Mats; Larhed, Mats

Ingår i Chem Commun (Camb), s. 790-1, 2004

Direct microwave synthesis of N,N'-diacylhydrazines and Boc-protected hydrazides by in situ carbonylations under air.

Herrero, Maria Antonia; Wannberg, Johan; Larhed, Mats

Ingår i Synlett, s. 2335-2338, 2004

Terminal Heck vinylations of chelating vinyl ethers.

Stadler, Alexander; von Schenck, Henrik; Vallin, Karl; Larhed, Mats et al.

Ingår i Advanced Synthesis & Catalysis, s. 1773-1781, 2004

Microwave-promoted and chelation-controlled double arylations of terminal olefinic carbon of vinyl ethers.

Svennebring, Andreas; Nilsson, Peter; Larhed, Mats

Ingår i J Org Chem, s. 3345-9, 2004

High-speed optimization of inhibitors of the malarial proteases plasmepsin I and II

Nöteberg, Daniel; Schaal, Wesley; Hamelink, Elizabeth; Vrang, Lotta et al.

Ingår i Journal of combinatorial chemistry, s. 456-464, 2003

• DOI för High-speed optimization of inhibitors of the malarial proteases plasmepsin I and II

Increasing Rates and Scope of Reactions: Sluggish Amines in Microwave-Heated Aminocarbonylation Reactions under Air

Wannberg, Johan; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 5750-5753, 2003

• DOI för Increasing Rates and Scope of Reactions: Sluggish Amines in Microwave-Heated Aminocarbonylation Reactions under Air

Arylboronic acids as versatile coupling partners in fast microwave promoted oxidative Heck chemistry

Andappan, Murugaiah; Nilsson, Peter; Larhed, Mats

Ingår i Molecular diversity, s. 97-106, 2003

• DOI för Arylboronic acids as versatile coupling partners in fast microwave promoted oxidative Heck chemistry

A New Highly Asymmetric Chelation-Controlled Heck Arylation

Nilsson, Peter; Larhed, Mats; Hallberg, Anders

Ingår i Journal of the American Chemical Society, s. 3430-3431, 2003

Microwave-assisted high-speed PCR

Fermér, Christian; Nilsson, Peter; Larhed, Mats

Ingår i European Journal of Pharmaceutical Sciences, s. 129-132, 2003

Rapid palladium-catalyzed synthesis of esters from aryl halides utilizing Mo(CO)6 as a solid carbon monoxide source

Georgsson, Jennie; Hallberg, Anders; Larhed, Mats

Ingår i Journal of Combinatorial Chemistry, s. 350-352, 2003

A Rapid Microwave Protocol for Heck Vinylation of Aryl Chlorides under Air

Datta, Gopal K.; Vallin, Karl S. A.; Larhed, Mats

Ingår i Molecular Diversity, s. 107-114, 2003

Ultrafast Chemistry: Cobalt Carbonyl-Mediated Synthesis of Diaryl Ketones under Microwave Irradiation

Enquist, Per-Anders; Nilsson, Peter; Larhed, Mats

Ingår i Organic Letters, s. 4875-4878, 2003

A rapid microwave protocol for Heck vinylation of aryl chlorides under air.

Datta, GK; Vallin, KS; Larhed, M

Ingår i Mol Divers, s. 107, 2003

High-Speed Heck Reactions in Ionic Liquid with Controlled Microwave Heating

Vallin, Karl S. A.; Emilsson, Per; Larhed, Mats; Hallberg, Anders

Ingår i J. Org. Chem., s. 6243-6246, 2002

Microwave-Assisted Enantioselective Heck Reactions: Expediting High Reaction Speed and Preparative Convenience

Nilsson, Peter; Gold, Henrik; Larhed, Mats; Hallberg, Anders

Ingår i Synthesis, s. 1611-1614, 2002

Fast Synthesis of Aryl Triflates with Controlled Microwave Heating

Bengtson, Anna; Hallberg, Anders; Larhed, Mats

Ingår i Organic Letters, s. 1231-1233, 2002

Protected Indanones by a Heck-Aldol Annulation Reaction

Bengtson, Anna; Larhed, Mats; Hallberg, Anders

Ingår i Journal of Organic Chemistry, s. 5854-5856, 2002

Aqueous DMF-Potassium Carbonate as a Substitute for Thallium and Silver Additives in the Palladium-Catalyzed Conversion of Aryl Bromides to Acetyl Arenes

Vallin, Karl S. A.; Larhed, Mats; Hallberg, Anders

Ingår i J. Org. Chem., s. 4340-4343, 2001

Highly Regioselective, Sequential and Multiple Palladium-Catalyzed Arylations of Vinyl Ethers Carrying a Coordinating Auxiliary: An Example of a Heck Triarylation Process

Nilsson, Peter; Larhed, Mats; Hallberg, Anders

Ingår i Journal of the American Chemical Society, s. 8217-8225, 2001

Highly Selective Palladium-Catalyzed Synthesis of Protected a,ß-Unsaturated Methyl Ketones and 2-Alkoxy-1,3-Butadienes: High-Speed Chemistry by Microwave Flash Heating

Vallin, Karl S. A.; Larhed, Mats; Johansson, Katarina; Hallberg, Anders

Ingår i J. Org. Chem., s. 4537-4542, 2000

New Regioselective Heck-Vinylation with Enamides. Synthesis and Investigation of Fluorous Tagged Bidentate Ligands for Fast Separation

Vallin, Karl S. A.; Zhang, Qisheng; Larhed, Mats; Curran, Dennis P. et al.

Ingår i J. Org. Chem.

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Hallberg, Mathias; Larhed, Mats

Ingår i Frontiers in Pharmacology, 2020

• DOI för From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase
• Ladda ner fulltext (pdf) av From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Aspartic protease inhibitors containing tertiary alcohol transition-state mimics

Motwani, Hitesh V.; De Rosa, Maria; Odell, Luke R.; Hallberg, Anders et al.

Ingår i European Journal of Medicinal Chemistry, s. 462-490, 2014

• DOI för Aspartic protease inhibitors containing tertiary alcohol transition-state mimics

Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

De Rosa, Maria; Gising, Johan; Odell, Luke R; Larhed, Mats

Ingår i Upsala Journal of Medical Sciences, s. 181-191, 2014

• DOI för Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

Controlled microwave heating as an enabling technology: Expedient synthesis of protease inhibitors in perspective

Larhed, Mats; Wannberg, Johan; Hallberg, Anders

Ingår i QSAR & combinatorial science (Print), s. 51-68, 2007

• DOI för Controlled microwave heating as an enabling technology: Expedient synthesis of protease inhibitors in perspective

Microwave-assisted synthesis of anti-tuberculosis, HIV and hepatitis C agents

Gising, Johan; Larhed, Mats; Odell, Luke R

Ingår i Microwaves in Drug Discovery and Development, s. 34-54, Future Medicine, 2014

• DOI för Microwave-assisted synthesis of anti-tuberculosis, HIV and hepatitis C agents

Microwave-Heated Transition Metal-Catalyzed Coupling Reactions

Russo, Francesco; Odell, Luke R; Olofsson, Kristofer; Nilsson, Peter et al.

Ingår i Microwaves in Organic Synthesis, s. 607-672, Wiley-VCH Verlagsgesellschaft, 2012

Microwave-Assisted Transition Metal-Catalyzed Asymmetric Synthesis

Odell, Luke R; Larhed, Mats

Ingår i Catalytic Methods in Asymmetric Synthesis, s. 391-412, Wiley-Blackwell, 2011

• DOI för Microwave-Assisted Transition Metal-Catalyzed Asymmetric Synthesis

Microwave-accelerated homogenous catalysis in water

Odell, Luke R; Larhed, Mats

Ingår i Handbook of green chemistry, s. 79-99, Wiley-VCH Verlagsgesellschaft, 2009

Focus on Regioselectivity and Product Outcome in Organic Synthesis

Nilsson, Peter; Olofsson, Kristofer; Larhed, Mats

Ingår i The Mizoroki-Heck Reaction, s. 133-162, John Wiley & Sons, 2009

• DOI för Focus on Regioselectivity and Product Outcome in Organic Synthesis

Accelerated Chemistry: Microwave, Sonochemical, and Fluorous Phase Techniques

Olofsson, Kristoffer; Nilsson, Peter; Larhed, Mats

Ingår i Exploiting chemical diversity for drug discovery, s. 33-48, Royal Chemical Society, 2006

• DOI för Accelerated Chemistry: Microwave, Sonochemical, and Fluorous Phase Techniques

Microwave Accelerated Metal Catalysis: Organic Transformations at Warp Speed

Olofsson, Kristoffer; Larhed, Mats

Ingår i Microwave Assisted Organic Synthesis, s. 25-43, Blackwell publishing, 2005

Palladium-Catalyzed Multiple and Asymmetric Arylations of Vinyl Ethers Carrying Coordinating Nitrogen Auxiliaries: Synthesis of Arylated Ketones and Aldehydes

Nilsson, Peter; Larhed, Mats

Ingår i Catalysts for the Fine Chemical Synthesis, Vol. 3, s. 92-99, John Wiley and Sons, 2004

Microwave-Assisted Fluorous Chemistry

Olofsson, Kristoffer; Larhed, Mats

Ingår i Handbook of Fluorous Chemistry, s. 359-365, Wiley-VCH, 2004

Transition metal-catalysis and microwave flash-heating in organic chemistry

Olofsson, Kristofer; Hallberg, Anders; Larhed, Mats

Ingår i Microwaves in Organic Synthesis, Wiley-VCH, 2002

• DOI för Transition metal-catalysis and microwave flash-heating in organic chemistry

Scope, Mechanism and Other Fundamental Aspects of the Intermolecular Heck Reaction

Larhed, M; Hallberg, A

Ingår i Handbook of Organopalladium Chemistry for Organic Synthesis, Wiley-Interscience, 2002

Experimental Techniques in Fluorous Synthesis: A users guide

Curran, D P; Hadida, S; Studer, A; He, M et al.

Ingår i Combinatorial Chemistry, s. 338-340, 2000

Synthesis and initial preclinical evaluation of the CRTH2 antagonist [C-11] MK-7246

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Ingår i Journal of Labelled Compounds and Pharmaceuticals, 2019

Theoretical Mechanistic Investigation of a Decarboxylative Heck Reaction with an Electron-Rich Olefin and Possible Catalyst Entrapment by the Heck Product

Fardost, Ashkan; Svensson, Fredrik; Larhed, Mats; Sköld, Christian

Non-peptide AT2-receptor agonists

Larhed, Mats; Hallberg, Mathias; Hallberg, Anders

Ingår i Medicinal Chemistry Reviews, 2016