Publications

Dual roles of exostosin glycosyltransferase 1 in Zika virus infection

Ling, Jiaxin; Khan, Asifa; Denkewitz, Matthias; Maccarana, Marco et al.

Part of Virulence, 2025

• DOI for Dual roles of exostosin glycosyltransferase 1 in Zika virus infection
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GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Netsyk, Olga; Korol, Sergiy V; Li, Jin-ping; Birnir, Bryndis et al.

Part of Journal of Alzheimer's Disease, p. 420-428, 2025

• DOI for GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation

Ling, Jiaxin; Lundkvist, Åke; Guerrini, Marco; Ferro, Vito et al.

Part of Advanced Science, 2024

• DOI for A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation

A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation

Ling, Jiaxin; Lundkvist, Åke; Guerrini, Marco; Ferro, Vito et al.

Part of Advanced Science, 2024

A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis

Li, Li; Barash, Uri; Ilan, Neta; Farhoud, Malik et al.

Part of Cells, 2024

• DOI for A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis
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Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses

Nahain, Abdullah Al; Li, Jinlin; Modhiran, Naphak; Watterson, Daniel et al.

Part of ACS Applied Bio Materials, p. 2862-2871, 2024

• DOI for Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses

Epigenetic Targeting of Heparan Sulfate 3-O- and 6-O-Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities

Bückreiß, Nico; Schulz-Fincke, Marie; König, Philipp; Maccarana, Marco et al.

Part of ACS Pharmacology & Translational Science, p. 2484-2495, 2024

• DOI for Epigenetic Targeting of Heparan Sulfate 3-O- and 6-O-Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities

Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity

Yu, Xiaolin; Duan, Guangfei; Pei, Pengfei; Chen, Long et al.

Part of eLIFE, 2024

• DOI for Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity
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Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts

Maccarana, Marco; Li, Binjie; Li, Honglian; Fang, Jianping et al.

Part of Glycobiology, 2024

• DOI for Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts
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Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review

Wu, Yiyang; Zhao, Siran; Wang, Jiandong; Chen, Yujuan et al.

Part of International Journal of Biological Macromolecules, 2024

• DOI for Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review
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Overview of the current procedures in synthesis of heparin saccharides

Zhao, Siran; Zhang, Tianji; Kan, Ying; Li, Hongmei et al.

Part of Carbohydrate Polymers, 2024

• DOI for Overview of the current procedures in synthesis of heparin saccharides
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Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

Yu, Xiaolin; Hu, Wenrui; Dong, Hang; Zhao, Tian et al.

Part of Biomacromolecules, p. 4374-4383, 2024

• DOI for Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue

Martinez, Hunter A.; Koliesnik, Ievgen; Kaber, Gernot; Reid, Jacqueline K. et al.

Part of Nature Communications, 2024

• DOI for Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
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Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism

McMillan, Ilayda Ozsan; Li, Jin-Ping; Wang, Lianchun

Part of American Journal of Physiology - Cell Physiology, 2023

• DOI for Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism

Heparanase Modulates Chromatin Accessibility

Li, Honglian; Zhang, Hua; Wenz, Amelie S.; Kang, Ziqi et al.

Part of Cells, 2023

• DOI for Heparanase Modulates Chromatin Accessibility
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Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing

Jiang, Lan; Zhang, Tianji; Lu, Hongzhong; Li, Saijuan et al.

Part of SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, p. 11-19, 2023

• DOI for Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing
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Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening

Li, Binjie; Zhang, Tianji; Cao, Hui; Ferro, Vito et al.

Part of International Journal of Molecular Sciences, 2023

• DOI for Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening
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In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels

Zhang, Tianji; Zhao, Siran; Chen, Yujuan; Wang, Jiandong et al.

Part of Carbohydrate Polymers, 2023

• DOI for In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels
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Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Zhang, Tianji; Yu, Mingjia; Li, Honglian; Maccarana, Marco et al.

Part of Carbohydrate Polymers, 2023

• DOI for Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?

Veraldi, Noemi; Quadri, Isabelle Dentand; van de Looij, Yohan; Modernell, Laura Malaguti et al.

Part of Carbohydrate Polymers, 2023

• DOI for Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?
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Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase

Doherty, Gareth G.; Ler, Geraldine Jia Ming; Wimmer, Norbert; Bernhardt, Paul V. et al.

Part of ChemBioChem, 2023

• DOI for Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase
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Antiviral Disaccharide Lead Compounds against SARS-CoV-2 through Computer-Aided High-Throughput Screen

Li, Binjie; Zhang, Tianji; Li, Jin-Ping; Yu, Ming-Jia

Part of ChemBioChem, 2022

• DOI for Antiviral Disaccharide Lead Compounds against SARS-CoV-2 through Computer-Aided High-Throughput Screen

GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer

Su, Linjia; Sun, Zhe; Qi, Fangzheng; Su, Huishan et al.

Part of Journal of Nanobiotechnology, 2022

• DOI for GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer
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Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model

Xiaowen, Cheng; Jia, Juan; Zhang, Tianji; Zhang, Xiao et al.

Part of Cells, 2022

• DOI for Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model
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Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells

Maccarana, Marco; Jia, Juan; Li, Honglian; Zhang, Xiao et al.

Part of International Journal of Molecular Sciences, 2022

• DOI for Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells
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Is heparan sulfate a target for inhibition of RNA virus infection?

Ling, Jiaxin; Li, Jinlin; Khan, Asifa; Lundkvist, Åke et al.

Part of American Journal of Physiology - Cell Physiology, 2022

• DOI for Is heparan sulfate a target for inhibition of RNA virus infection?

Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate

Xue, Song; Zhou, Fan; Zhao, Tian; Zhao, Huimin et al.

Part of Nature Communications, 2022

• DOI for Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate
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Comprehensive Landscape of Heparin Therapy for COVID-19

Shi, Chen; Tingting, Wu; Li, Jin-Ping; Sullivan, Mitchell A. et al.

Part of Carbohydrate Polymers, 2021

• DOI for Comprehensive Landscape of Heparin Therapy for COVID-19

Development and Validation of a Nomogram for Assessing Survival in Patients With COVID-19 Pneumonia

Dong, Yi-Min; Sun, Jia; Li, Yi-Xin; Chen, Qian et al.

Part of Clinical Infectious Diseases, p. 652-660, 2021

• DOI for Development and Validation of a Nomogram for Assessing Survival in Patients With COVID-19 Pneumonia

Dichotomic role of heparanase in a murine model of metabolic syndrome

Hermano, Esther; Carlotti, Francoise; Abecassis, Alexia; Meirovitz, Amichay et al.

Part of Cellular and Molecular Life Sciences (CMLS), p. 2771-2780, 2021

• DOI for Dichotomic role of heparanase in a murine model of metabolic syndrome

Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival

Agelidis, Alex; Turturice, Benjamin A.; Suryawanshi, Rahul K.; Yadavalli, Tejabhiram et al.

Part of JCI Insight, 2021

• DOI for Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival
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Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling

Yu, Mingjia; Zhang, Tianji; Li, Jin-Ping; Tan, Yingxia

Part of ChemistryOpen, p. 966-975, 2021

• DOI for Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling
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Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic

Yu, Mingjia; Zhang, Tianji; Zhang, Wei; Sun, Qianyun et al.

Part of Frontiers in Molecular Biosciences, 2021

• DOI for Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic
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Glucuronyl C5-epimerase is crucial for epithelial cell maturation during embryonic lung development

Cui, Hao; Xiaowen, Cheng; Batool, Tahira; Zhang, Xiao et al.

Part of Glycobiology, p. 223-230, 2021

• DOI for Glucuronyl C5-epimerase is crucial for epithelial cell maturation during embryonic lung development

Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium

Van Bergen, Tine; Etienne, Isabelle; Jia, Juan; Li, Jin-Ping et al.

Part of Current Eye Research, p. 1166-1170, 2021

• DOI for Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium

Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease

Zhang, Xiao; O'Callaghan, Paul; Li, Honglian; Tan, Ying-Xia et al.

Part of Acta neuropathologica communications, 2021

• DOI for Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease
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Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts

Maccarana, Marco; Tykesson, Emil; Pera, Edgar M.; Gouignard, Nadege et al.

Part of Glycobiology, p. 1319-1329, 2021

• DOI for Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts

Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

Gockel, Lukas M.; Heyes, Martin; Li, Honglian; Al Nahain, Abdullah et al.

Part of ACS Applied Materials and Interfaces, p. 7080-7093, 2021

• DOI for Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease

Hammoud, Hayma; Netsyk, Olga; Tafreshiha, Atieh S.; Korol, Sergiy V. et al.

Part of Acta Physiologica, 2021

• DOI for Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease
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Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase

Cui, Hao; Wang, Zhaoguang; Zhang, Tianji; Li, Jin-Ping et al.

Part of Glycobiology, p. 1018-1025, 2021

• DOI for Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase

Reply to Collins et al

Dong, Yi-Min; Sun, Jia; Aude Andrée, Bengobesse Biyoche; Chen, Qian et al.

Part of Clinical Infectious Diseases, p. 558-559, 2021

• DOI for Reply to Collins et al

Characterization of anti-BCG benz[α]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomycete Nocardia sp. XJ31

Zhang, Li; Zhang, Jingyu; Ren, Biao; Lu, Wanying et al.

Part of Applied Microbiology and Biotechnology, p. 8267-8278, 2020

• DOI for Characterization of anti-BCG benz[α]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomycete Nocardia sp. XJ31

Diagnostic performance of initial blood urea nitrogen combined with D-dimer levels for predicting in-hospital mortality in COVID-19 patients

Cheng, Anying; Hu, Liu; Wang, Yiru; Huang, Luyan et al.

Part of International Journal of Antimicrobial Agents, 2020

• DOI for Diagnostic performance of initial blood urea nitrogen combined with D-dimer levels for predicting in-hospital mortality in COVID-19 patients

Glycosaminoglycans in biological samples: towards identification of novel biomarkers

Zhang, Tianji; Zhang, Rui; Lv, Yongqin; Wang, Meng et al.

Part of TrAC. Trends in analytical chemistry, 2020

• DOI for Glycosaminoglycans in biological samples: towards identification of novel biomarkers

Heparanase: Discovery and Targets

Lindahl, Ulf; Li, Jin-Ping

Part of Heparanase, p. 61-69, Springer, 2020

• DOI for Heparanase: Discovery and Targets

Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway

Wan, Lu Ming; Zhang, Shi Kun; Li, Su Bo; Li, Wen et al.

Part of Thrombosis and Haemostasis, p. 647-657, 2020

• DOI for Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway

Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis

Yang, Wen-Jing; Zhang, Gan-Lin; Cao, Ke-Xin; Liu, Xiao-Ni et al.

Part of International Journal of Oncology, p. 890-904, 2020

• DOI for Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis
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Heparin: An old drug with multiple potential targets in Covid-19 therapy

Lindahl, Ulf; Li, Jin-Ping

Part of Journal of Thrombosis and Haemostasis, p. 2422-2424, 2020

• DOI for Heparin: An old drug with multiple potential targets in Covid-19 therapy

High-throughput screening identified mitoxantrone to induce death of hepatocellular carcinoma cells with autophagy involvement

Xie, Bushan; He, Xingxing; Guo, Guihai; Zhang, Xiao et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 232-237, 2020

• DOI for High-throughput screening identified mitoxantrone to induce death of hepatocellular carcinoma cells with autophagy involvement

Implications of Heparan Sulfate and Heparanase in Amyloid Diseases

Li, Jin-Ping; Zhang, Xiao

Part of Advances in Experimental Medicine and Biology, p. 631-645, 2020

• DOI for Implications of Heparan Sulfate and Heparanase in Amyloid Diseases