Publikationer

Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis

Hu, Binhong; Yao, Ling; Deng, Xin; Zhao, Wei et al.

Ingår i Frontiers in Nutrition, 2026

• DOI för Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis
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Streptomyces: boost chassis strains for production of invaluable natural products

Chen, Simin; Ling, Siqi; Li, Jinpin; Liu, Zhiyan et al.

Ingår i SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, s. 515-535, 2026

• DOI för Streptomyces: boost chassis strains for production of invaluable natural products
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Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid

Wu, Yiyang; Chen, Yujuan; Zhao, Siran; Wan, Jinyu et al.

Ingår i Synthetic and systems biotechnology, s. 437-446, 2026

• DOI för Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid
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A Novel Series of Synthetic Heparin-Mimetics-Itaconic Acid-Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis

Nekipelov, Katrin; Al Nahain, Abdullah; Otto, Sven; Xu, Yongbin et al.

Ingår i Macromolecular Bioscience, 2025

• DOI för A Novel Series of Synthetic Heparin-Mimetics-Itaconic Acid-Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis
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CpG-A induces liquid-liquid phase separation of HMGB1 to activate the RAGE-mediated inflammatory pathway

Peng, Kaihui; Fu, Gaohong; Chen, Long; Xie, Jiazhi et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2025

• DOI för CpG-A induces liquid-liquid phase separation of HMGB1 to activate the RAGE-mediated inflammatory pathway
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De Novo Sequencing of Enoxaparin Oligosaccharides through HILIC-Q-cIM-MS: A Strategy for Resolving Complex Glycans

Zhao, Siran; Yang, Xuexin; Cao, Hui; Li, Ming et al.

Ingår i Analytical Chemistry, s. 15706-15716, 2025

• DOI för De Novo Sequencing of Enoxaparin Oligosaccharides through HILIC-Q-cIM-MS: A Strategy for Resolving Complex Glycans

Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium

Wu, Ruoxuan; Zhang, Tianji; Zhao, Siran; Maccarana, Marco et al.

Ingår i Frontiers in Bioengineering and Biotechnology, 2025

• DOI för Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium
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Dual roles of exostosin glycosyltransferase 1 in Zika virus infection

Ling, Jiaxin; Khan, Asifa; Denkewitz, Matthias; Maccarana, Marco et al.

Ingår i Virulence, 2025

• DOI för Dual roles of exostosin glycosyltransferase 1 in Zika virus infection
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GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Netsyk, Olga; Korol, Sergiy V; Li, Jin-ping; Birnir, Bryndis et al.

Ingår i Journal of Alzheimer's Disease, s. 420-428, 2025

• DOI för GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Spatially Decoupled Electro-Biosystem for Efficient CO2-to-Chemicals Conversion via Tandem Catalysis

Han, Lin; Li, Yan; Wang, Xuyuan; Yao, Zhibo et al.

Ingår i Advanced Energy Materials, 2025

• DOI för Spatially Decoupled Electro-Biosystem for Efficient CO2-to-Chemicals Conversion via Tandem Catalysis

Structure-Function Relationships of Heparan Sulfate-Based Neoproteoglycans as Selective Immunostimulatory Scaffolds

Chandra, Ankita; Maccarana, Marco; Vishweshwara, Sharath S.; Mardhekar, Sandhya et al.

Ingår i Chemistry - A European Journal, 2025

• DOI för Structure-Function Relationships of Heparan Sulfate-Based Neoproteoglycans as Selective Immunostimulatory Scaffolds

The deficiency of chymase mast cell protease 4 exacerbates dextran sulfate sodium salt-induced colitis in mice and is associated with altered microbiota and metabolome profiles

Li, Zhiqiang; Kuang, Xiaoyuan; Mo, Dashuang; Åbrink, Magnus et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2025

• DOI för The deficiency of chymase mast cell protease 4 exacerbates dextran sulfate sodium salt-induced colitis in mice and is associated with altered microbiota and metabolome profiles
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A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation

Ling, Jiaxin; Lundkvist, Åke; Guerrini, Marco; Ferro, Vito et al.

Ingår i Advanced Science, 2024

• DOI för A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation
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A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis

Li, Li; Barash, Uri; Ilan, Neta; Farhoud, Malik et al.

Ingår i Cells, 2024

• DOI för A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis
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Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses

Nahain, Abdullah Al; Li, Jinlin; Modhiran, Naphak; Watterson, Daniel et al.

Ingår i ACS Applied Bio Materials, s. 2862-2871, 2024

• DOI för Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses

Epigenetic Targeting of Heparan Sulfate 3-O- and 6-O-Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities

Bückreiß, Nico; Schulz-Fincke, Marie; König, Philipp; Maccarana, Marco et al.

Ingår i ACS Pharmacology & Translational Science, s. 2484-2495, 2024

• DOI för Epigenetic Targeting of Heparan Sulfate 3-O- and 6-O-Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities

Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity

Yu, Xiaolin; Duan, Guangfei; Pei, Pengfei; Chen, Long et al.

Ingår i eLIFE, 2024

• DOI för Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity
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Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts

Maccarana, Marco; Li, Binjie; Li, Honglian; Fang, Jianping et al.

Ingår i Glycobiology, 2024

• DOI för Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts
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Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review

Wu, Yiyang; Zhao, Siran; Wang, Jiandong; Chen, Yujuan et al.

Ingår i International Journal of Biological Macromolecules, 2024

• DOI för Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review
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Overview of the current procedures in synthesis of heparin saccharides

Zhao, Siran; Zhang, Tianji; Kan, Ying; Li, Hongmei et al.

Ingår i Carbohydrate Polymers, 2024

• DOI för Overview of the current procedures in synthesis of heparin saccharides
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Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

Yu, Xiaolin; Hu, Wenrui; Dong, Hang; Zhao, Tian et al.

Ingår i Biomacromolecules, s. 4374-4383, 2024

• DOI för Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue

Martinez, Hunter A.; Koliesnik, Ievgen; Kaber, Gernot; Reid, Jacqueline K. et al.

Ingår i Nature Communications, 2024

• DOI för Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
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Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism

McMillan, Ilayda Ozsan; Li, Jin-Ping; Wang, Lianchun

Ingår i American Journal of Physiology - Cell Physiology, 2023

• DOI för Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism

Heparanase Modulates Chromatin Accessibility

Li, Honglian; Zhang, Hua; Wenz, Amelie S.; Kang, Ziqi et al.

Ingår i Cells, 2023

• DOI för Heparanase Modulates Chromatin Accessibility
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Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing

Jiang, Lan; Zhang, Tianji; Lu, Hongzhong; Li, Saijuan et al.

Ingår i SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, s. 11-19, 2023

• DOI för Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing
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Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening

Li, Binjie; Zhang, Tianji; Cao, Hui; Ferro, Vito et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening
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In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels

Zhang, Tianji; Zhao, Siran; Chen, Yujuan; Wang, Jiandong et al.

Ingår i Carbohydrate Polymers, 2023

• DOI för In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels
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Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Zhang, Tianji; Yu, Mingjia; Li, Honglian; Maccarana, Marco et al.

Ingår i Carbohydrate Polymers, 2023

• DOI för Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?

Veraldi, Noemi; Quadri, Isabelle Dentand; van de Looij, Yohan; Modernell, Laura Malaguti et al.

Ingår i Carbohydrate Polymers, 2023

• DOI för Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?
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Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase

Doherty, Gareth G.; Ler, Geraldine Jia Ming; Wimmer, Norbert; Bernhardt, Paul V. et al.

Ingår i ChemBioChem, 2023

• DOI för Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase
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Antiviral Disaccharide Lead Compounds against SARS-CoV-2 through Computer-Aided High-Throughput Screen

Li, Binjie; Zhang, Tianji; Li, Jin-Ping; Yu, Ming-Jia

Ingår i ChemBioChem, 2022

• DOI för Antiviral Disaccharide Lead Compounds against SARS-CoV-2 through Computer-Aided High-Throughput Screen

GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer

Su, Linjia; Sun, Zhe; Qi, Fangzheng; Su, Huishan et al.

Ingår i Journal of Nanobiotechnology, 2022

• DOI för GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer
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Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model

Xiaowen, Cheng; Jia, Juan; Zhang, Tianji; Zhang, Xiao et al.

Ingår i Cells, 2022

• DOI för Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model
• Ladda ner fulltext (pdf) av Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model

Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells

Maccarana, Marco; Jia, Juan; Li, Honglian; Zhang, Xiao et al.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells
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Is heparan sulfate a target for inhibition of RNA virus infection?

Ling, Jiaxin; Li, Jinlin; Khan, Asifa; Lundkvist, Åke et al.

Ingår i American Journal of Physiology - Cell Physiology, 2022

• DOI för Is heparan sulfate a target for inhibition of RNA virus infection?

Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate

Xue, Song; Zhou, Fan; Zhao, Tian; Zhao, Huimin et al.

Ingår i Nature Communications, 2022

• DOI för Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate
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Comprehensive Landscape of Heparin Therapy for COVID-19

Shi, Chen; Tingting, Wu; Li, Jin-Ping; Sullivan, Mitchell A. et al.

Ingår i Carbohydrate Polymers, 2021

• DOI för Comprehensive Landscape of Heparin Therapy for COVID-19

Development and Validation of a Nomogram for Assessing Survival in Patients With COVID-19 Pneumonia

Dong, Yi-Min; Sun, Jia; Li, Yi-Xin; Chen, Qian et al.

Ingår i Clinical Infectious Diseases, s. 652-660, 2021

• DOI för Development and Validation of a Nomogram for Assessing Survival in Patients With COVID-19 Pneumonia

Dichotomic role of heparanase in a murine model of metabolic syndrome

Hermano, Esther; Carlotti, Francoise; Abecassis, Alexia; Meirovitz, Amichay et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 2771-2780, 2021

• DOI för Dichotomic role of heparanase in a murine model of metabolic syndrome

Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival

Agelidis, Alex; Turturice, Benjamin A.; Suryawanshi, Rahul K.; Yadavalli, Tejabhiram et al.

Ingår i JCI Insight, 2021

• DOI för Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival
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Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling

Yu, Mingjia; Zhang, Tianji; Li, Jin-Ping; Tan, Yingxia

Ingår i ChemistryOpen, s. 966-975, 2021

• DOI för Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling
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Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic

Yu, Mingjia; Zhang, Tianji; Zhang, Wei; Sun, Qianyun et al.

Ingår i Frontiers in Molecular Biosciences, 2021

• DOI för Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic
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Glucuronyl C5-epimerase is crucial for epithelial cell maturation during embryonic lung development

Cui, Hao; Xiaowen, Cheng; Batool, Tahira; Zhang, Xiao et al.

Ingår i Glycobiology, s. 223-230, 2021

• DOI för Glucuronyl C5-epimerase is crucial for epithelial cell maturation during embryonic lung development

Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium

Van Bergen, Tine; Etienne, Isabelle; Jia, Juan; Li, Jin-Ping et al.

Ingår i Current Eye Research, s. 1166-1170, 2021

• DOI för Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium

Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease

Zhang, Xiao; O'Callaghan, Paul; Li, Honglian; Tan, Ying-Xia et al.

Ingår i Acta neuropathologica communications, 2021

• DOI för Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease
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Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts

Maccarana, Marco; Tykesson, Emil; Pera, Edgar M.; Gouignard, Nadege et al.

Ingår i Glycobiology, s. 1319-1329, 2021

• DOI för Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts

Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

Gockel, Lukas M.; Heyes, Martin; Li, Honglian; Al Nahain, Abdullah et al.

Ingår i ACS Applied Materials and Interfaces, s. 7080-7093, 2021

• DOI för Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease

Hammoud, Hayma; Netsyk, Olga; Tafreshiha, Atieh S.; Korol, Sergiy V. et al.

Ingår i Acta Physiologica, 2021

• DOI för Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease
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Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase

Cui, Hao; Wang, Zhaoguang; Zhang, Tianji; Li, Jin-Ping et al.

Ingår i Glycobiology, s. 1018-1025, 2021

• DOI för Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase

Reply to Collins et al

Dong, Yi-Min; Sun, Jia; Aude Andrée, Bengobesse Biyoche; Chen, Qian et al.

Ingår i Clinical Infectious Diseases, s. 558-559, 2021

• DOI för Reply to Collins et al