Preclinical PET-MRI Platform (PPP)

A platform at Uppsala University for radiolabelling and preclinical and translational molecular imaging
Preclinical PET-MRI Platform (PPP)
A platform at Uppsala University for radiolabelling and preclinical and translational molecular imaging
Positron Emission Tomography (PET) and Single Photon Emission Tomography (SPECT) are emerging methodologies in the field of molecular imaging. At the platform we bridge the gap between basic research in medicinal chemistry and clinical application of molecular imaging with PET, SPECT, MRI and CT. We develop tracers for preclinical validation using state-of-the-art in vivo and in vitro methodologies. Our small animal scanners are PET-MRI, SPECT-CT and PET-SPECT-CT. We also have access to a clinical PET-CT and PET-MRI scanners in collaboration with Uppsala Accademical Hospital.
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Facilities and equipment
Read more about the PPP facilities and our equipment. We are nationally available for researcher for projects within that can benefit form molecular imaging and/or radiochemistry.
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Molecular imaging and radionuclide techniques
Read more about molecular imaging and radionuclide techniques for drug development.

Project application and user fees
Apply here for the list of user fees and to use PPP for your research project.

Group members
Publications
Part of Molecular Cancer Therapeutics, p. 753-762, 2025
- DOI for Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
- Download full text (pdf) of Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
Part of Intensive Care Medicine Experimental, 2025
- DOI for Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
- Download full text (pdf) of Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools
Part of Scientific Reports, 2025
- DOI for Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools
- Download full text (pdf) of Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools
Antibody engagement with amyloid‐beta does not inhibit [11C]PiB binding for PET imaging
Part of Journal of Neurochemistry, p. 2601-2610, 2024
- DOI for Antibody engagement with amyloid‐beta does not inhibit [11C]PiB binding for PET imaging
- Download full text (pdf) of Antibody engagement with amyloid‐beta does not inhibit [11C]PiB binding for PET imaging
Part of Journal of Nuclear Medicine, p. 294-299, 2024