Preclinical PET-MRI Platform (PPP)

A platform at Uppsala University for radiolabelling and preclinical and translational molecular imaging
Preclinical PET-MRI Platform (PPP)
A platform at Uppsala University for radiolabelling and preclinical and translational molecular imaging
Positron Emission Tomography (PET) and Single Photon Emission Tomography (SPECT) are emerging methodologies in the field of molecular imaging. At the platform we bridge the gap between basic research in medicinal chemistry and clinical application of molecular imaging with PET, SPECT, MRI and CT. We develop tracers for preclinical validation using state-of-the-art in vivo and in vitro methodologies. Our small animal scanners are PET-MRI, SPECT-CT and PET-SPECT-CT. We also have access to a clinical PET-CT and PET-MRI scanners in collaboration with Uppsala Accademical Hospital.
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Facilities and equipment
Read more about the PPP facilities and our equipment. We are nationally available for researcher for projects within that can benefit form molecular imaging and/or radiochemistry.
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Molecular imaging and radionuclide techniques
Read more about molecular imaging and radionuclide techniques for drug development.

Project application and user fees
Apply here for the list of user fees and to use PPP for your research project.

Group members
Publications
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Preclinical evaluation of an antibody-based companion diagnostic for CD44v6 expressing cancer
Part of Nuclear medicine communications, p. 401-410, 2026
- DOI for Preclinical evaluation of an antibody-based companion diagnostic for CD44v6 expressing cancer
- Download full text (pdf) of Preclinical evaluation of an antibody-based companion diagnostic for CD44v6 expressing cancer
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Part of Journal of Nuclear Medicine, p. 269-275, 2026
- DOI for Preclinical Validation of [177Lu]Lu-AKIR001, a CD44v6-Targeted Radiotherapeutic Entering First-in-Human Trials
- Download full text (pdf) of Preclinical Validation of [177Lu]Lu-AKIR001, a CD44v6-Targeted Radiotherapeutic Entering First-in-Human Trials
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Part of Molecular Cancer Therapeutics, p. 753-762, 2025
- DOI for Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
- Download full text (pdf) of Dual-Nuclide Biodistribution and Therapeutic Evaluation of a Novel Antibody-Based Radiopharmaceutical in Anaplastic Thyroid Cancer Xenografts
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Part of Intensive Care Medicine Experimental, 2025
- DOI for Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
- Download full text (pdf) of Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools
Part of Scientific Reports, 2025
- DOI for Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools
- Download full text (pdf) of Targeting mutant p53: Evaluation of novel anti-p53R175H monoclonal antibodies as diagnostic tools