Our current publications

Column coupling for chiral LC-MS separation resolves triacylglycerol enantiomers and regioisomers in complex samples without flow recycling

Nilsson, Jenny M.; Balgoma, David; Stephansson, Edvin Dedering; Landström, Sofia et al.

Part of Talanta, 2027

• DOI for Column coupling for chiral LC-MS separation resolves triacylglycerol enantiomers and regioisomers in complex samples without flow recycling
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A Separation Buffers Platform Set to Facilitate CZE Charge Heterogeneity Method Development for Monoclonal Antibodies

Baxter, Joanne; Waltham, Kevin; Fitton, Lori; Sänger-van de Griend, Cari

Part of Electrophoresis, p. 420-434, 2026

• DOI for A Separation Buffers Platform Set to Facilitate CZE Charge Heterogeneity Method Development for Monoclonal Antibodies

Biodegradable plastics in anaerobic digestion environment

Gunasekara, Channa

2026

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Development and optimisation of an UHPLC-MS/MS method for analysis of veterinary drug residues – hormones in urine

Claesdóttir, Klara

2026

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Development of a Nonaqueous Capillary Electrophoresis SeparationMethod for Hexetidine and Related Impurities

Khalid, Mahroze

2026

Development of an SFC-MS Method for Separation and Identification of Major Lipid Classes in Human Hepatocellular Carcinoma Cells

Johansson, Mikaela

2026

Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses

Ekstrand, Carl; Michanek, Peter; Hernlund, Elin; Gehring, Ronette et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 22-32, 2026

• DOI for Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses
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Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats

Niessen, Janis; Koziolek, Mirko; Borchardt, Thomas; Indulkar, Anura S. et al.

Part of Journal of Controlled Release, 2026

• DOI for Effects of intestinal permeation enhancers on solubilization and epithelial transport of the proteolysis targeting chimera (PROTAC) ARV-471 in rats
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Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1

Krompholz, Marlon; Blanc, Timothy; Lu, Huixin; Christensen, Patricia et al.

Part of Electrophoresis, p. 276-294, 2026

• DOI for Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1
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Optimisation and validation of a UPLC–MS/MS method for quantitative analysis of glycoalkaloids in potato products, with extension to aubergine

Mohamed, Amina Faysal

2026

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Optimisation and validation of an UPLC-MS/MS method for analysis of veterinary drug residues (coccidiostats & nitroimidazoles) in Bovine liver

Sverlinger, Gabriella

2026

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Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH

Haglöf, Jakob; Regnell, Julia; Sänger-van de Griend, Cari

Part of Analytica Chimica Acta, 2026

• DOI for Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH
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The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)

Niessen, Janis; Koziolek, Mirko; Indulkar, Anura; Borchardt, Thomas et al.

Part of Molecular Pharmaceutics, p. 3445-3457, 2026

• DOI for The In Vivo Effect of Amorphous Drug Nanoprecipitates on the Intestinal Absorption of the PROTACs ARV-110 (Bavdeglutamide) and ARV-471 (Vepdegestrant)
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A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats

Niessen, Janis; Arendt, Nathalie; Sjöblom, Markus; Dubbelboer, Ilse R. et al.

Part of European journal of pharmaceutics and biopharmaceutics, 2025

• DOI for A comprehensive mechanistic investigation of factors affecting intestinal absorption and bioavailability of two PROTACs in rats
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A Novel Approach for the Analysis of microDNA and microRNA Using Capillary Zone Electrophoresis

Regnell, Julia

2025

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A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

Tricht, Ewoud van; Sänger-van de Griend, Cari

Part of Electrophoresis, p. 933-953, 2025

• DOI for A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development
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Canagliflozin: Pharmacokinetics, tolerability and glucose/insulin effects of supratherapeutic doses in healthy horses

Michanek, Peter; Bröjer, Johan; Lilliehöök, Inger; Fjordbakk, Cathrine et al.

Part of The Veterinary Journal, 2025

• DOI for Canagliflozin: Pharmacokinetics, tolerability and glucose/insulin effects of supratherapeutic doses in healthy horses
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Developing a HPLC-UV and HPLC-MS compatible method for analysis of water-soluble vitamins in plasma solutions.

Keyvani, Arvand

2025

Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis

Haglöf, Jakob; Nilsson, Jenny M.; Ludvigsson, Jufang Wu

Part of Journal of Separation Science, 2025

• DOI for Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
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Development of LC-MS method forenantiomeric separation oftriacylglycerols from rat liver tissue: Determination doxorubicin’s effect on TG enantiomercontent in liver

Stephansson, Edvin

2025

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Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis

Haglöf, Jakob; Bivehed, Erik; Sänger-van de Griend, Cari

Part of Talanta, 2025

• DOI for Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
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Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs

Sjolund, Marie; Rosendal, Thomas; Wallgren, Per; Pringle, Maerit et al.

Part of Acta Veterinaria Scandinavica, 2025

• DOI for Improved pharmacotherapy after revised dosing regimens of two slow-release formulations of benzylpenicillin in an Actinobacillus pleuropneumoniae infection model in pigs
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Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin

Kopsida, Maria; Regtop, Lotta; Lennernäs, Hans; Hedeland, Mikael et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, 2025

• DOI for Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin
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Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia

Engskog-Vlachos, Pinelopi; Engskog, Mikael K R; Skandik, Martin; Grabert, Kathleen et al.

Part of Journal of Neurochemistry, 2025

• DOI for Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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Method Development and Validation for Beta-Agonists in Liver and Urine using UHPLC-MS/MS, according to EU-Legislation 2021/808

Al Sahli, Maram Samih

2025

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Oligomeric profiling of liraglutide and semaglutide under different conditions using a validated SEC-HPLC-UV method

Nehlin, Sara

2025

Peak Integration of Electropherograms in GMP and Research Labs: Navigating Increased Scrutiny Amid Data Integrity Audits and Inspections

Blanc, Timothy; Wätzig, Hermann; Sänger-van de Griend, Cari

Part of Electrophoresis, p. 653-668, 2025

• DOI for Peak Integration of Electropherograms in GMP and Research Labs: Navigating Increased Scrutiny Amid Data Integrity Audits and Inspections
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Personalized Veterinary Tablets for FIP Treatment Using 3D Printing: Development, Content Uniformity, and Stability Testing of GS-441524 with the CuraVet System

Tahhan, Eyad

2025

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Pharmacokinetics and Alterations in Glucose and Insulin Levels After a Single Dose of Canagliflozin in Healthy Icelandic Horses

Michanek, Peter; Bröjer, Johan; Lilliehöök, Inger; Fjordbakk, Cathrine T et al.

Part of Journal of Veterinary Pharmacology and Therapeutics, p. 41-49, 2025

• DOI for Pharmacokinetics and Alterations in Glucose and Insulin Levels After a Single Dose of Canagliflozin in Healthy Icelandic Horses
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The collateral damage of chemotherapy: A time-dependent view of triacylglycerols in doxorubicin-treated rats

Westerberg, Leo

2025

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Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε-Aminocaproic Acid and Triethylenetetramine

Baxter, Joanne; Fitton, Lori; Sänger-van de Griend, Cari

Part of Electrophoresis, p. 1645-1650, 2025

• DOI for Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε-Aminocaproic Acid and Triethylenetetramine
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Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)

Niessen, Janis; Nilsson, Jenny M.; Peters, Karsten; Indulkar, Anura et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, 2024

• DOI for Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)
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Elevated plasma level of arginine and its metabolites at labor among women with preeclampsia: A prospective cohort study

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Larsson, Anders et al.

Part of American Journal of Hypertension, p. 184-191, 2024

• DOI for Elevated plasma level of arginine and its metabolites at labor among women with preeclampsia: A prospective cohort study
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Elevated Plasma Levels of Arginines During Labor Among Women with Spontaneous Preterm Birth: A Prospective Cohort Study

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Ubhayasekera, Kumari et al.

Part of American Journal of Reproductive Immunology, 2024

• DOI for Elevated Plasma Levels of Arginines During Labor Among Women with Spontaneous Preterm Birth: A Prospective Cohort Study
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Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells

Kopsida, Maria; Clavero, Ada Lerma; Khaled, Jaafar; Balgoma, David et al.

Part of Molecular Metabolism, 2024

• DOI for Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells
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Metabolite Profiling of Drugs using Mass Spectrometry: Identification of analytical targets for doping control and improvements of the metabolite search process

Nilsson Broberg, Malin

2024

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Screening of RP-HPLC purification conditions for GLP-1 analogues

Voss, Linn

2024

Text Mining and Computational Chemistry Reveal Trends in Applications of Laser Desorption/Ionization Techniques to Small Molecules

Bergman, Nina P.; Bergquist, Jonas; Hedeland, Mikael; Palmblad, Magnus

Part of Journal of the American Society for Mass Spectrometry, p. 2507-2515, 2024

• DOI for Text Mining and Computational Chemistry Reveal Trends in Applications of Laser Desorption/Ionization Techniques to Small Molecules
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A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites

Nilsson Broberg, Malin; Tillgren Ohlsson, Rebecca; Bondesson, Ulf; Pettersson, Curt et al.

Part of Journal of chromatography. B, 2023

• DOI for A multivariate data analysis approach for the investigation of in vitro derived metabolites of ACP-105 in comparison with human in vivo metabolites
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An interlaboratory capillary zone electrophoresis-UV study of various monoclonal antibodies, instruments, and ε-aminocaproic acid lots

Wiesner, Rebecca; Zagst, Holger; Lan, Wenkui; Bigelow, Stewart et al.

Part of Electrophoresis, p. 1247-1257, 2023

• DOI for An interlaboratory capillary zone electrophoresis-UV study of various monoclonal antibodies, instruments, and ε-aminocaproic acid lots
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Combining the targeted and untargeted screening of environmental contaminants reveals associations between PFAS exposure and vitamin D metabolism in human plasma.

Carlsson, Henrik; Sreenivasan, Akshai P.; Erngren, Ida; Larsson, Anders et al.

Part of Environmental Science, p. 1116-1130, 2023

• DOI for Combining the targeted and untargeted screening of environmental contaminants reveals associations between PFAS exposure and vitamin D metabolism in human plasma.
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DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Bivehed, Erik; Hellman, Björn; Fan, Yuting; Haglöf, Jakob et al.

Part of Mutation research. Genetic toxicology and environmental mutagenesis, 2023

• DOI for DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
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Enantiomeric Separation of Triacylglycerols from Mouse Liver Tissue using CSP-LC-MS/MS

Landström, Sofia

2023

Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control

Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt et al.

Part of Journal of Pharmaceutical and Biomedical Analysis, 2023

• DOI for Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
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Functionalization of cellulose nanofibrils to develop novel ROS-sensitive biomaterials

Palo-Nieto, Carlos; Blasi-Romero, Anna; Sandström, Corine; Balgoma, David et al.

Part of Materials Advances, p. 1555-1565, 2023

• DOI for Functionalization of cellulose nanofibrils to develop novel ROS-sensitive biomaterials
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Identification and Structural Elucidation of Cannabinoid Metabolites in Horse Urine Using UHPLC-HRMS

Morén, Agnes

2023

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Investigation of degradation of toxic substances in fungal cultures by mass spectrometric techniques

Stenholm, Åke

2023

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Optimization of a Microsome Incubation Method using Design of Experiment and Investigation of Metabolites Derived from GLPG0492 and LY2452473: For Application in Doping Control

Tillgren Ohlsson, Rebecca

2023

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Plasma levels of arginines at term pregnancy in relation to mode of onset of labor and mode of childbirth

Akhter, Tansim; Hedeland, Mikael; Bergquist, Jonas; Ubhayasekera, Kumari et al.

Part of American Journal of Reproductive Immunology, 2023

• DOI for Plasma levels of arginines at term pregnancy in relation to mode of onset of labor and mode of childbirth
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Recent capillary electrophoresis applications for upstream and downstream biopharmaceutical process monitoring

van der Burg, Debbie; Josefsson, Leila; Emmer, Åsa; Sänger–van de Griend, Cari E.

Part of TrAC. Trends in analytical chemistry, 2023

• DOI for Recent capillary electrophoresis applications for upstream and downstream biopharmaceutical process monitoring
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