Pharmaceutical Physical Chemistry
The research group in Pharmaceutical Physical Chemistry at Uppsala University
Our research clarifies the relationship between the molecular structure of drug molecules, their physicochemical properties and the possibilities to control how they are stored in and released from different types of particulate drug carriers and formulations.
We create new knowledge making it possible to develop new or improved systems for the administration of drugs, including macromolecular drugs such as peptides and proteins, and small and amphiphilic drug molecules including cancer drugs. We combine experimental and theoretical methods in the border area between physical chemistry, drug formulation and materials science.
Subcutaneous drug delivery
Research with a focus on in-depth understanding of parental administration of drugs.
Amphiphilic properties of drug molecules
Research with a focus on amphiphilic properties of drug molecules and their self-assemble in the presence of phospholipids.
Gels for drug delivery
Research with a focus on fundamental aspects of the interaction between hydrogels and different types of active substances and excipients.
Contact us
Contact the employees in our group
Selected reading
A selection of our publications.
Current publications
- Wanselius, Marcus; Abrahmsen-Alami, Susanna; Hanafy, Belal I. et al., 2024
- Al-Tikriti, Yassir; Hansson, Per, 2024
- Rosenquist Lybecker, Jenny; van de Ven, Ann; Braesch-Andersen, Ken et al.
Meet our researchers
Meet our teachers and researchers in Pharmaceutical physical chemistry
This is up in our group
Here you will find the latest news from our research group in Pharmaceutical Physical Chemistry.
Tech & Tools
Learn more about the extensive selection of powerful machinery and tools at our research environment.
Our alumni
Meet our former colleagues in Pharmaceutical Physical Chemistry that have moved on to new challenges.
Publications
Part of International Journal of Biological Macromolecules, 2026
- DOI for Diffusion of Affibody molecules in extracellular matrix mimetic hydrogels and the effect of albumin binding
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Diffusion of macromolecules in extracellular matrix mimetic hydrogels: effect of size and charge
Part of European Journal of Pharmaceutical Sciences, 2025
- DOI for Diffusion of macromolecules in extracellular matrix mimetic hydrogels: effect of size and charge
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Interaction of Sodium Polystyrenesulfonate with Fluorinated Ionic Surfactant of Opposite Charge
Part of Langmuir, p. 26673-26682, 2025
- DOI for Interaction of Sodium Polystyrenesulfonate with Fluorinated Ionic Surfactant of Opposite Charge
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Part of Powder Technology, 2025
- DOI for The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering
- Download full text (pdf) of The micro-structure of lactose powder compacts studied by small-angle and ultra small-angle X-ray scattering
Part of International Journal of Pharmaceutics, 2024
- DOI for A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration
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A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels
Part of Colloids and Surfaces A, 2024
- DOI for A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels
- Download full text (pdf) of A small-angle X-ray scattering study of amphiphilic drug self-assemblies in polyacrylate microgels
Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space
Part of European Polymer Journal, 2024
- DOI for Engineering and characterization of a hydrogel mimicking subcutaneous interstitial space
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Part of International Journal of Pharmaceutics, 2024
Part of Drug Delivery and Translational Research, p. 970-983, 2023
- DOI for Quantitative imaging of doxorubicin diffusion and cellular uptake in biomimetic gels with human liver tumor cells
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Part of International Journal of Pharmaceutics, 2023
- DOI for Utilizing a Microfluidic Platform to Investigate Drug-Eluting Beads: Binding and Release of Amphiphilic Antidepressants
- Download full text (pdf) of Utilizing a Microfluidic Platform to Investigate Drug-Eluting Beads: Binding and Release of Amphiphilic Antidepressants