Particle toxicology

Description

Project manager: Hanna Karlsson

In our projects, we investigate toxic effects, underlying mechanisms, and potential health risks associated with a wide range of particles. Our work includes particles containing metals in the form of engineered nanoparticles as well as those generated during processes such as 3D printing and welding. We also study microplastics and particles formed through tire wear, along with those found in environments such as airports and subway systems. A key focus of our research is to understand how different particle properties – for example, their size – can influence biological effects. We also work on modelling how particles behave in the lung and on studying exposure in so‑called air‑liquid interface systems.

An essential part of our research is the development and evaluation of various cell models, with the aim of deepening the understanding of particle‑related health effects while at the same time providing alternatives to animal testing. The research field spans both fundamental questions about interactions between materials and biological systems and applied studies designed to provide scientific evidence for authorities and policymakers.