Biopharmaceuticals
Immunotherapeutics
The research group in Professor Mangsbo’s laboratory focuses on drug development in the field of protein-, peptide-, and oligonucleotide-based therapeutics, as well as on building functional model systems that enable disease and intervention studies.
Protein drug design - ProDDe
In Greta Hultqvist group we develop protein drugs and transporters through rational in silico design to understand the mechanism behind diseases and how can we treat them.
Since the success with the production of recombinant insulin for treatment of diabetes, we have succeeded in the generation of chimeric antibodies, humanized antibodies and complete human antibodies that are able to treat a rapidly growing number of diseases. Phage display technology along with advanced recombinant protein strategies have advanced the field since early 2000.
Novel targets and protein designs are constantly evolving and novel strategies for drug delivery to improve efficacy and reduce toxicity is key to the future success. The protein and peptide drug groups headed by Professor S Mangsbo and Senior lecturer G Hultqvist perform research related to protein/peptide drug therapeutics with a focus on utilizing passive and active immunotherapy approaches to treat diseases linked to neurogenerative, inflammatory and oncology conditions. Their work center around innovative strategies to improve protein and peptide drugs, protein conjugate drugs and advanced characterization of the biology behind the therapeutic efficacy achieved by the novel drug entity.
Read more about Sara's and Greta's research groups.
ADDRESS
VISITING ADDRESS:
Biomedical center: A1:2, A3:3, B3:3, B3:4, D3:3, D3:4
Husargatan 3
UPPSALA
LETTER AND PARCEL ADDRESS:
Institutionen för Farmaci
Box 580
751 23 UPPSALA
ON-TRACT EU network
We are working together with European leaders in the EU network ON-TRACT, a network developing the next generation oligonucleotide-based drugs.
Contact
- Visiting Address: BMC, Husargatan 3, A1:2, A2:2, A3:3, B3:3, B3:4, C2:2
- Letter and Postal Address: Box 580, SE-751 23 Uppsala