Biopharmaceuticals
Immuno-oncology
Sara Mangsbo's research work is oriented towards development and evaluation of novel biologicals and combinations thereof, where activation of tumor-specific T cells is key.
Protein drug design - ProDDe
In Greta Hultqvist group we develop protein drugs and transporters through rational in silico design to understand the mechanism behind diseases and how can we treat them.
Since the success with the production of recombinant insulin for treatment of diabetes, we have succeeded in the generation of chimeric antibodies, humanized antibodies and complete human antibodies that are able to treat a rapidly growing number of diseases. Phage display technology along with advanced recombinant protein strategies have advanced the field since early 2000.
Novel targets and protein designs are constantly evolving and novel strategies for drug delivery to improve efficacy and reduce toxicity is key to the future success. The protein and peptide drug groups headed by Associate senior lecturer Greta Hultqvist and Associate senior lecturer Sara Mangsbo center around protein/peptide drug therapeutics with a focus on utilizing passive and active immunotherapy approaches to treat diseases like Alzheimer and bladder cancer. Their work center around innovative strategies to improve protein drugs and advanced characterization of the biology behind the therapeutic efficacy achieved by the novel drug entity.
Read more about Sara's and Greta's research groups.
ADDRESS
VISITING ADDRESS:
Biomedical center: A1:2, A3:3, B3:3, B3:4, D3:3, D3:4
Husargatan 3
UPPSALA
LETTER AND PARCEL ADDRESS:
Institutionen för Farmaci
Box 580
751 23 UPPSALA
Contact
- Visiting Address: BMC, Husargatan 3, A1:2, A2:2, A3:3, B3:3, B3:4, C2:2
- Letter and Postal Address: Box 580, SE-751 23 Uppsala