Doctoral thesis and Research articles

Timed Up-and-Go Dual-Task Tests for Early Detection of Dementia Disorder

Åhman, Hanna Bozkurt

2021

Doctoral thesis, comprehensive summary

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Independent Ageing in Very Old Swedish Men

Franzon, Kristin

2019

Doctoral thesis, comprehensive summary

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Cathepsin S as a Biomarker of Low-grade Inflammation, Insulin Resistance, and Cardiometabolic Disease Risk

Jobs, Elisabeth

2014

Doctoral thesis, comprehensive summary

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Physical Activity and Alzheimer's Disease: Measurements, Observations and Subjective Experiences

Cedervall, Ylva

2014

Doctoral thesis, comprehensive summary

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The Kidney in Different Stages of the Cardiovascular Continuum

Nerpin, Elisabet

2013

Doctoral thesis, comprehensive summary

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Biomarkers as Monitors of Drug Effect, Diagnostic Tools and Predictors of Deterioration Rate in Alzheimer’s Disease

Degerman Gunnarsson, Malin

2013

Doctoral thesis, comprehensive summary

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Prostate Cancer; Metabolic Risk Factors, Drug Utilisation, Adverse Drug Reactions

Grundmark, Birgitta

2013

Doctoral thesis, comprehensive summary

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Predictors of Dementia: Insulin, Fatty Acids and Vascular Risk Factors

Rönnemaa, Elina

2012

Doctoral thesis, comprehensive summary

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Amyloid β-protein, Cystatin C and Cathepsin B as Biomarkers of Alzheimer's Disease

Sundelöf, Johan

2010

Doctoral thesis, comprehensive summary

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Risk Factors for Stroke in Adult Men: A Population-based Study

Wiberg, Bernice

2010

Doctoral thesis, comprehensive summary

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The Impact of Bariatric Surgery on Obesity related Metabolic Traits with Specific Emphasis on Glucose, Insulin and Proinsulin

Johansson, Hans-Erik

2010

Doctoral thesis, comprehensive summary

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Measurement Variability Related to Insulin Secretion and Sensitivity: Assessment and Implications in Epidemiological Studies

Berglund, Lars

2009

Doctoral thesis, comprehensive summary

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Insulin Resistance and Inflammation as Risk Factors for Congestive Heart Failure

Ingelsson, Erik

2005

Doctoral thesis, comprehensive summary

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Clinical Manifestations of Coronary Heart Disease and the Metabolic Syndrome: A Population-based Study in Middle-aged Men in Uppsala

Dunder, Kristina

2004

Doctoral thesis, comprehensive summary

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General Motor Function Assessment and Perceptions of Life Satisfaction during and after Geriatric Rehabilitation

Åberg, Anna Cristina

2003

Doctoral thesis, comprehensive summary

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Proinsulin and Insulin Sensitivity as Predictors of Type 2 Diabetes Mellitus and Coronary Heart Disease: Clinical Epidemiological Studies with up to 27 Years of Follow-Up

Zethelius, Björn

2002

Doctoral thesis, comprehensive summary

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Left Ventricular Function in Elderly Men: Metabolic, Hormonal, Genetic and Prognostic Implications

Ärnlöv, Johan

2002

Doctoral thesis, comprehensive summary

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24-hour Ambulatory Blood Pressure - Relation to the Insulin Resistance Syndrome and Cardiovascular Disease

Björklund, Kristina

2002

Doctoral thesis, comprehensive summary

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Plasminogen Activator Inhibitor-1 and the Insulin Resistance Syndrome

Byberg, Liisa

2002

Doctoral thesis, comprehensive summary

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Magnesium and the Insulin Resistance Syndrome

Hänni, Arvo

2001

Doctoral thesis, comprehensive summary

Muscle Morphology and the Insulin Resistance Syndrome: A Population-Based Study of 70 Year-Old-Men in Uppsala

Hedman, Anu

2001

Doctoral thesis, comprehensive summary

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Left ventricular hypertrophy and the insulin resistance syndrome

Sundström, Johan

2001

Doctoral thesis, comprehensive summary

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Machine Learning Approaches for Dementia Detection Through Speech and Gait Analysis: A Systematic Literature Review

Al-Hammadi, Mustafa; Fleyeh, Hasan; Åberg, Anna Cristina; Halvorsen, Kjartan et al.

Part of Journal of Alzheimer's Disease, p. 1-27, 2024

Article, review/survey

• DOI for Machine Learning Approaches for Dementia Detection Through Speech and Gait Analysis: A Systematic Literature Review
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Adaptation of a guided low-intensity behavioral activation intervention for people with dementia in Sweden: a qualitative study exploring the needs and preferences of key stakeholders

Blomberg, Oscar; Svedin, Frida; Farrand, Paul; Brantnell, Anders et al.

Part of BMC Geriatrics, 2024

Article in journal

• DOI for Adaptation of a guided low-intensity behavioral activation intervention for people with dementia in Sweden: a qualitative study exploring the needs and preferences of key stakeholders
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Failure to Involve Older Hospitalised Patients in Medication Decisions: A Change of Approach is Called For

Cam, Henrik; Gillespie, Ulrika; Kälvemark Sporrong, Sofia; Nielsen, Elisabet I. et al.

Part of Research in Social and Administrative Pharmacy, p. 216-217, 2024

Article in journal

• DOI for Failure to Involve Older Hospitalised Patients in Medication Decisions: A Change of Approach is Called For

Day-to-day variability of stress biomarkers during a music intervention in people living with dementia and their family caregivers

Emami, Azita; Jun, Jeehye; Theorell, Töres; Engström, Gabriella et al.

Part of Science Progress, 2024

Article in journal

• DOI for Day-to-day variability of stress biomarkers during a music intervention in people living with dementia and their family caregivers
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Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Part of Acta neuropathologica communications, 2024

Article in journal

• DOI for Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
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Validation of a web-based self-administered test for cognitive assessment in a Swedish geriatric setting

Rystedt, Einar; Moren, Jakob; Lindbäck, Johan; Tedim Cruz, Vitor et al.

Part of PLOS ONE, 2024

Article in journal

• DOI for Validation of a web-based self-administered test for cognitive assessment in a Swedish geriatric setting
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, Ken; Giedraitis, Vilmantas; Ingelsson, Martin; Lind, Lars et al.

Part of Nature, p. 347-357, 2024

Article in journal

• DOI for Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
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Obstructive sleep apnea during rapid eye movement sleep and cognitive performance in adults

Tan, Xiao; Ljunggren, Mirjam; Kilander, Lena; Benedict, Christian et al.

Part of Sleep Medicine, p. 34-40, 2024

Article in journal

• DOI for Obstructive sleep apnea during rapid eye movement sleep and cognitive performance in adults
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Factors associated with changes in walking performance in individuals 3 months after stroke or TIA: secondary analyses from a randomised controlled trial of SMS-delivered training instructions in Sweden

Vahlberg, Birgit; Eriksson, Staffan; Holmbäck, Ulf; Lundström, Erik

Part of BMJ Open, 2024

Article in journal

• DOI for Factors associated with changes in walking performance in individuals 3 months after stroke or TIA: secondary analyses from a randomised controlled trial of SMS-delivered training instructions in Sweden
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A meta-analysis of previous falls and subsequent fracture risk in cohort studies

Vandenput, Liesbeth; Johansson, Helena; McCloskey, Eugene V.; Liu, Enwu et al.

Part of Osteoporosis International, p. 469-494, 2024

Article in journal

• DOI for A meta-analysis of previous falls and subsequent fracture risk in cohort studies

Herpes Simplex Viral Infection Doubles the Risk of Dementia in a Contemporary Cohort of Older Adults: A Prospective Study

Vestin, Erika; Boström, Gustaf; Olsson, Jan; Elgh, Fredrik et al.

Part of Journal of Alzheimer's Disease, p. 1841-1850, 2024

Article in journal

• DOI for Herpes Simplex Viral Infection Doubles the Risk of Dementia in a Contemporary Cohort of Older Adults: A Prospective Study
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Genetic and Environmental Factors and Cardiovascular Disease Risk in Adolescents

Ballin, Marcel; Neovius, Martin; Ortega, Francisco B.; Henriksson, Pontus et al.

Part of JAMA Network Open, 2023

Article in journal

• DOI for Genetic and Environmental Factors and Cardiovascular Disease Risk in Adolescents
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Loci for insulin processing and secretion provide insight into type 2 diabetes risk.

Broadaway, K Alaine; Yin, Xianyong; Williamson, Alice; Parsons, Victoria A et al.

Part of American Journal of Human Genetics, p. 284-299, 2023

Article in journal

• DOI for Loci for insulin processing and secretion provide insight into type 2 diabetes risk.

The complexities of communication at hospital discharge of older patients: a qualitative study of healthcare professionals' views

Cam, Henrik; Wennlöf, Björn; Gillespie, Ulrika; Franzon, Kristin et al.

Part of BMC Health Services Research, 2023

Article in journal

• DOI for The complexities of communication at hospital discharge of older patients: a qualitative study of healthcare professionals' views
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Response to comment on "Assessment of executive functions in older adults: Translation and initial validation of the Swedish version of the frontal assessment battery, FAB-Swe"

Damberg, Mattias; Pellas, Johnny

Part of Applied neuropsychology. Adult, p. 636-637, 2023

Article in journal

• DOI for Response to comment on "Assessment of executive functions in older adults: Translation and initial validation of the Swedish version of the frontal assessment battery, FAB-Swe"

Associations between lifestyle factors and levels of per- and polyfluoroalkyl substances (PFASs), phthalates and parabens in follicular fluid in women undergoing fertility treatment

Hallberg, Ida; Duque Björvang, Richelle; Hadziosmanovic, Nermin; Koekkoekk, Jacco et al.

Part of Journal of Exposure Science and Environmental Epidemiology, p. 699-709, 2023

Article in journal

• DOI for Associations between lifestyle factors and levels of per- and polyfluoroalkyl substances (PFASs), phthalates and parabens in follicular fluid in women undergoing fertility treatment
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Feasibility of PURPOSE T in clinical practice and patient participation: a mixed-method study

Hultin, Lisa; Karlsson, Ann-Christin; Löwenmark, Malin; Coleman, Susanne et al.

Part of International Wound Journal, p. 633-647, 2023

Article in journal

• DOI for Feasibility of PURPOSE T in clinical practice and patient participation: a mixed-method study
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Previous fracture and subsequent fracture risk: a meta-analysis to update FRAX

Kanis, J. A.; Johansson, H.; McCloskey, E. , V; Liu, E. et al.

Part of Osteoporosis International, p. 2027-2045, 2023

Article in journal

• DOI for Previous fracture and subsequent fracture risk: a meta-analysis to update FRAX

Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Le Guen, Yann; Luo, Guo; Ambati, Aditya; Damotte, Vincent et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2023

Article in journal

• DOI for Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
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Association between atherogenic lipids and GnRH agonists for prostate cancer in men with T2DM: a nationwide, population-based cohort study in Sweden

Lin, E.; Garmo, Hans; Hagström, Emil; Van Hemelrijck, Mieke et al.

Part of British Journal of Cancer, p. 814-824, 2023

Article in journal

• DOI for Association between atherogenic lipids and GnRH agonists for prostate cancer in men with T2DM: a nationwide, population-based cohort study in Sweden
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The impact of stroke on the ability to live an independent life at old age: a community-based cohort study of Swedish men

Lindvall, Elias; Franzon, Kristin; Lundström, Erik; Kilander, Lena

Part of BMC Geriatrics, 2023

Article in journal

• DOI for The impact of stroke on the ability to live an independent life at old age: a community-based cohort study of Swedish men
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Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease

Luo, Jiao; Thomassen, Jesper Qvist; Bellenguez, Celine; Grenier-Boley, Benjamin et al.

Part of JAMA Network Open, 2023

Article in journal

• DOI for Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
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Safety and effectiveness of monovalent COVID-19 mRNA vaccination and risk factors for hospitalisation caused by the omicron variant in 0.8 million adolescents: A nationwide cohort study in Sweden

Nordstrom, Peter; Ballin, Marcel; Nordstrom, Anna

Part of PLoS Medicine, 2023

Article in journal

• DOI for Safety and effectiveness of monovalent COVID-19 mRNA vaccination and risk factors for hospitalisation caused by the omicron variant in 0.8 million adolescents: A nationwide cohort study in Sweden
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Neuromuscular controller models for quantifying standing balance in older people: A systematic review

Olsson, Fredrik; Halvorsen, Kjartan; Åberg, Anna Cristina

Part of IEEE Reviews in Biomedical Engineering, p. 560-578, 2023

Article in journal

• DOI for Neuromuscular controller models for quantifying standing balance in older people: A systematic review

Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events

Rietz, Helene; Pennlert, Johanna; Nordström, Peter; Brunström, Mattias

Part of Annals of Internal Medicine, p. 1289-1298, 2023

Article in journal

• DOI for Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events

Healthcare and community stakeholders' perceptions of barriers and facilitators to implementing a behavioral activation intervention for people with dementia and depression: a qualitative study using Normalization Process Theory

Svedin, Frida; Blomberg, Oscar; Brantnell, Anders; Farrand, Paul et al.

Part of BMC Geriatrics, 2023

Article in journal

• DOI for Healthcare and community stakeholders' perceptions of barriers and facilitators to implementing a behavioral activation intervention for people with dementia and depression: a qualitative study using Normalization Process Theory
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Effectiveness, acceptability, and completeness and quality of intervention reporting of psychological interventions for people with dementia or mild cognitive impairment: protocol for a mixed-methods systematic review

Svedin, Frida; Blomberg, Oscar; Farrand, Paul; Brantnell, Anders et al.

Part of BMJ Open, 2023

Article in journal

• DOI for Effectiveness, acceptability, and completeness and quality of intervention reporting of psychological interventions for people with dementia or mild cognitive impairment: protocol for a mixed-methods systematic review
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High Self‐Reported Levels of Pain 1 Year After a Myocardial Infarction Are Related to Long‐Term All‐Cause Mortality: A SWEDEHEART Study Including 18 376 Patients

Vixner, Linda; Hambraeus, Kristina; Äng, Björn; Berglund, Lars

Part of Journal of the American Heart Association, 2023

Article in journal

• DOI for High Self‐Reported Levels of Pain 1 Year After a Myocardial Infarction Are Related to Long‐Term All‐Cause Mortality: A SWEDEHEART Study Including 18 376 Patients
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Longitudinal Effects of Herpesviruses on Multiple Cognitive Outcomes in Healthy Elderly Adults

Weidung, Bodil; Josefsson, Maria; Lyttkens, Peter; Olsson, Jan et al.

Part of Journal of Alzheimer's Disease, p. 751-762, 2023

Article in journal

• DOI for Longitudinal Effects of Herpesviruses on Multiple Cognitive Outcomes in Healthy Elderly Adults
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Temporal Dementia and Cognitive Impairment Trends in the Very Old in the 21st Century

Weidung, Bodil; Lovheim, Hugo; Littbrand, Hakan; Wahlin, Johanna et al.

Part of Journal of Alzheimer's Disease, p. 61-74, 2023

Article in journal

• DOI for Temporal Dementia and Cognitive Impairment Trends in the Very Old in the 21st Century
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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Williamson, Alice; Norris, Dougall M; Yin, Xianyong; Broadaway, K Alaine et al.

Part of Nature Genetics, p. 973-983, 2023

Article in journal

• DOI for Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts

Zanetti, Daniela; Stell, Laurel; Gustafsson, Stefan; Abbasi, Fahim et al.

Part of Diabetologia, p. 1643-1654, 2023

Article in journal

• DOI for Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts
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Dual-Task Interference of Gait Parameters During Different Conditions of the Timed Up-and-Go Test Performed by Community-Dwelling Older Adults

Åberg, Anna Cristina; Larsson, Liss Elin; Giedraitis, Vilmantas; Berglund, Lars et al.

Part of Journal of Aging and Physical Activity, p. 823-832, 2023

Article in journal

• DOI for Dual-Task Interference of Gait Parameters During Different Conditions of the Timed Up-and-Go Test Performed by Community-Dwelling Older Adults
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Prediction of conversion to dementia disorders based on timed up and go dual-task test verbal and motor outcomes: a five-year prospective memory-clinic-based study

Åberg, Anna Cristina; Petersson, Johanna R.; Giedraitis, Vilmantas; Mckee, Kevin J. et al.

Part of BMC Geriatrics, 2023

Article in journal

• DOI for Prediction of conversion to dementia disorders based on timed up and go dual-task test verbal and motor outcomes: a five-year prospective memory-clinic-based study
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New insights into the genetic etiology of Alzheimer's disease and related dementias

Bellenguez, Celine; Giedraitis, Vilmantas; Ingelsson, Martin; Lambert, Jean-Charles

Part of Nature Genetics, p. 412-436, 2022

Article in journal

• DOI for New insights into the genetic etiology of Alzheimer's disease and related dementias
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Follicular fluid and blood levels of persistent organic pollutants and reproductive outcomes among women undergoing assisted reproductive technologies

Bjorvang, Richelle D.; Hallberg, Ida; Pikki, Anne; Berglund, Lars et al.

Part of Environmental Research, 2022

Article in journal

• DOI for Follicular fluid and blood levels of persistent organic pollutants and reproductive outcomes among women undergoing assisted reproductive technologies
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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Gorski, Mathias; Rasheed, Humaira; Teumer, Alexander; Thomas, Laurent F. et al.

Part of Kidney International, p. 624-639, 2022

Article in journal

• DOI for Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies
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CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Konstantinidis, Evangelos; Molisak, Agnieszka; Perrin, Florian; Streubel-Gallasch, Linn et al.

Part of Molecular Therapy Nucleic Acids, p. 450-461, 2022

Article in journal

• DOI for CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation
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Mixed Pathologies in a Subject with a Novel PSEN1 G206R Mutation

Libard, Sylwia; Giedraitis, Vilmantas; Kilander, Lena; Ingelsson, Martin et al.

Part of Journal of Alzheimer's Disease, p. 1601-1614, 2022

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• DOI for Mixed Pathologies in a Subject with a Novel PSEN1 G206R Mutation
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Association of Gonadotropin-Releasing Hormone Agonists for Prostate Cancer With Cardiovascular Disease Risk and Hypertension in Men With Diabetes

Lin, E.; Garmo, Hans; Van Hemelrijck, Mieke; Zethelius, Björn et al.

Part of JAMA Network Open, 2022

Article in journal

• DOI for Association of Gonadotropin-Releasing Hormone Agonists for Prostate Cancer With Cardiovascular Disease Risk and Hypertension in Men With Diabetes
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Self-reported physical activity and different cardiovascular diseases-Results from updated measurements over 40 years

Lind, Lars; Zethelius, Björn; Byberg, Liisa

Part of PLOS ONE, 2022

Article in journal

• DOI for Self-reported physical activity and different cardiovascular diseases-Results from updated measurements over 40 years
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PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer's disease risk

Lindman, Karin Lopatko; Jonsson, Caroline; Weidung, Bodil; Olsson, Jan et al.

Part of Scientific Reports, 2022

Article in journal

• DOI for PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer's disease risk
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Comparison of years of life lost to 1,565 suicides versus 10,650 COVID-19 deaths in 2020 in Sweden: four times more years of life lost per suicide than per COVID-19 death

Ljung, Rickard; Grünewald, Maria; Sundström, Anders; Thunander Sundbom, Lena et al.

Part of Upsala Journal of Medical Sciences, 2022

Article in journal

• DOI for Comparison of years of life lost to 1,565 suicides versus 10,650 COVID-19 deaths in 2020 in Sweden: four times more years of life lost per suicide than per COVID-19 death
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Long-term time trends in reactivated herpes simplex infections and treatment in Sweden

Lopatko Lindman, Karin; Lockman-Lundgren, Judith; Weidung, Bodil; Olsson, Jan et al.

Part of BMC Infectious Diseases, 2022

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• DOI for Long-term time trends in reactivated herpes simplex infections and treatment in Sweden
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, Anubha; Spracklen, Cassandra N.; Zhang, Weihua; Ng, Maggie C. Y. et al.

Part of Nature Genetics, p. 560-572, 2022

Article in journal

• DOI for Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Blood pressure screening in midlife aids in prediction of dementia later in life

Moberg, Lena; Leppert, Jerzy; Liljeström, Simon; Rehn, Mattias et al.

Part of Upsala Journal of Medical Sciences, 2022

Article in journal

• DOI for Blood pressure screening in midlife aids in prediction of dementia later in life
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Milk and Fermented Milk Consumption and Risk of Stroke: Longitudinal Study

Olsson, Erika; Larsson, Susanna C.; Höijer, Jonas; Kilander, Lena et al.

Part of Nutrients, 2022

Article in journal

• DOI for Milk and Fermented Milk Consumption and Risk of Stroke: Longitudinal Study
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Mutation analysis of disease causing genes in patients with early onset or familial forms of Alzheimer’s disease and frontotemporal dementia

Pagnon de la Vega, María; Näslund, Carl; Brundin, RoseMarie; Lannfelt, Lars et al.

Part of BMC Genomics, 2022

Article in journal

• DOI for Mutation analysis of disease causing genes in patients with early onset or familial forms of Alzheimer’s disease and frontotemporal dementia
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Women with Fibromyalgia Prefer Resistance Exercise with Heavy Load: A Randomized Crossover Pilot Study

Andersson, Ulf Mathias; Åberg, Anna Cristina; von Koch, Lena; Palstam, Annie

Part of International Journal of Environmental Research and Public Health, 2021

Article in journal

• DOI for Women with Fibromyalgia Prefer Resistance Exercise with Heavy Load: A Randomized Crossover Pilot Study
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Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease

Bergström, Sofia; Remnestål, Julia; Yousef, Jamil; Olofsson, Jennie et al.

Part of Annals of Clinical and Translational Neurology, p. 1456-1470, 2021

Article in journal

• DOI for Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease
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