Research at Uppsala University
History of human antibiotic use written in the oral bacteria of wild brown bears
25 August 2021. An international team of researchers used historical museum collections to study the effects of huma ...
How research can encourage us to cycle instead
19 August 2021. How do you get to work in the mornings? Transport currently accounts for 25 per cent of GHG emission ...
Philippine ethnic group has most Denisovan DNA
13 August 2021. The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relat ...
Search for research projects
Here you will find all research projects at Uppsala University funded by the main Swedish funding bodies. The search feature is based on the SweCRIS database.
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Your choice produced 28 hits
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Accelerated Early staGe drug diScovery
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Research project from 2016-01-01 to 2020-01-01
The development of effective novel drugs - especially for rare and neglected diseases - is one of the biggest challenges of the upcoming decades, as illustrated by the recent Ebola outbreak. Moreover, ...
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Advanced aRchitectures for ultra-thin high-efficiency CIGS solar cells with high Manufacturability
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Research project from 2016-12-01 to 2019-11-30
Advanced aRchitectures for ultra-thin high-efficiency CIGS solar cells with high Manufacturability (ARCIGS-M) This project´s goal is advanced materials and nanotechnologies for novel CIGS PV device architectures ...
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Alphaviral Immunotherapy against Glioblastoma
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Research project from 2016-05-01 to 2018-04-30
Alphaviral Immunotherapy against Glioblastoma Glioblastomas (GBM) are the most frequent type of primary brain tumours with no treatment or cure available. Despite the current standard care, GBMs remain ...
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Bridging the gap: an evolutionary genomics approach to illuminate the prokaryote-to-eukaryote transition.
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Research project from 2017-01-01 to 2018-12-31
Eukarya – one of the three Domains of Life along with Archaea and Bacteria (i.e. prokaryotes) – include all complex multicellular life forms, as well as a colossal diversity of unicellular microorganisms ...
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Chemistry and Biology in Synergy - Studies of hydrogenases using a combination of synthetic chemistry and biological tools
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Research project from 2017-02-01 to 2022-01-31
My proposal aims to take advantage of my ground-breaking finding that it is possible to mature, or activate, the [FeFe] hydrogenase enzyme (HydA) using synthetic mimics of its catalytic [2Fe] cofactor. ...
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Combining Single Molecule and Ensemble approaches To Investigate Cas9 Target Search
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Research project from 2016-04-01 to 2018-03-31
The CRISPR-Cas9 bacterial immune system has garnered intense interest both as a synthetic biology tool and as a biological system in its own right. Yet the ability of Cas9 to find its guide-RNA-directed ...
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Contexts, networks and participation: The social logic of political engagement
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Research project from 2016-09-01 to 2021-08-31
The statement that individuals’ immediate social circumstances influence how they think and act in the political sphere is a truism. However, both theoretical and empirical considerations have often prevented ...
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Coordination and Composability: The Keys to Efficient Memory System Design
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Research project from 2017-03-01 to 2022-02-28
Computer systems today are power limited. As a result, efficiency gains can be translated into performance. Over the past decade we have been so effective at making computation more efficient that we are ...
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Digital readout of protein detection via super rolling circle amplification of DNA tags
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Research project from 2015-10-01 to 2017-03-31
This project will serve to evaluate market opportunities of a newly invented technology for digital detection of reporter DNA strands in protein analysis. The purpose of my ongoing ERC project ProteinSeq ...
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Dynamics of Supersymmetry in Curved Space
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Research project from 2015-09-01 to 2020-08-31
Quantum field theory provides a theoretical framework to explain quantitatively natural phenomena as diverse as the fluctuations in the cosmic microwave background, superconductivity, and elementary particle ...
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EPOS Implementation Phase
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Research project from 2015-10-01 to 2019-10-01
The nations of Europe are distributed around some of the most complex and dynamic geological systems on the planet and understanding these is essential to the security of livelihoods and economic power ...
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Evolutionary Stability of Ubiquitous Root Symbiosis
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Research project from 2016-04-01 to 2021-03-31
Virtually all terrestrial plants depend on symbiotic interactions with fungi. Arbuscular mycorrhizal (AM) fungi evolved over 450 million years ago, are obligate biotrophs and cannot complete their lifecycle ...
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Fundamental and Applied Science on Molecular Redox-Catalysts of Energy Relevance in Metal-Organic Frameworks
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Research project from 2017-01-01 to 2021-12-31
Organometallic redox-catalysts of energy relevance, i.e. water and hydrogen oxidation, and proton and carbon dioxide reduction catalysts, will be incorporated into metal-organic frameworks (MOFs). Immobilization ...
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Integrating spatial and genetic information via automated image analysis and interactive visualization of tissue data
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Research project from 2016-04-01 to 2021-03-31
Digital imaging of tissue samples and genetic analysis by next generation sequencing are two rapidly emerging fields in pathology. The exponential growth in digital imaging in pathology is catalyzed by ...
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Intestinal Lipoidal Nanostructures - A Lipid Bridge to Increased Drug Delivery
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Research project from 2015-09-01 to 2020-08-31
My research program explores molecular interplay between drug, dosage form and the complex environment of the gastrointestinal tract (GIT). Drug molecules currently being discovered to cure e.g. CNS diseases ...
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Jigsaw puzzles at atomic resolution: Computational design of GPCR drugs from fragments
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Research project from 2017-11-01 to 2022-10-31
Despite technological advances, industry struggles to develop new pharmaceuticals and therefore novel strategies for drug discovery are urgently needed. G protein-coupled receptors (GPCRs) play important ...
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Molecularly defined models of human childhood brain tumors
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Research project from 2015-05-01 to 2020-04-30
MYC proteins like MYC and MYCN are transcription factors that are mis-regulated in more than half of all types of human cancer including medulloblastoma, the most common brain malignancy in children. The ...
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Mosaic loss of chromosome Y (LOY) in blood cells - a new biomarker for risk of cancer and Alzheimer’s disease in men
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Research project from 2016-03-01 to 2021-02-28
My recent discoveries show that mosaic loss of chromosome Y (LOY) in peripheral blood is associated with increased risks of cancer and Alzheimer’s disease (AD). These conditions are responsible for >50% ...
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Organ-specific mechanisms of lymphatic vascular development and specialisation
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Research project from 2015-05-01 to 2020-04-30
Lymphatic vasculature maintains tissue fluid homeostasis and has important emerging roles in inflammation, immunity, lipid metabolism, blood pressure regulation and cancer metastasis. Lymphatic vessels ...
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Patient Preferences in benefit risk assessments during the drug life cycle
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Research project from 2016-11-16 to 2021-09-30
The PREFER project will deliver an overview and evaluation of preference elicitation methods to be applied in the entire drug life cycle, i.e. in the early stages of identifying medical needs, in clinical ...
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Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes
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Research project from 2016-01-01 to 2020-01-01
Environmental microbial surveys have revealed a remarkable diversity of microeukaryotic life in most ecosystems, the majority of which had previously escaped detection. From an ecological point of view ...
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Single-Molecule And Structural Studies Of ATP-Dependent Chromatin Remodelling
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Research project from 2017-03-01 to 2022-02-28
The packaging of genetic information into chromatin regulates a wide range of vital processes that depend on direct access to the DNA template. Many chromatin-interacting complexes impact chromatin structure ...
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Soccermatics: data for football fans and clubs
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Research project from 2017-08-01 to 2019-01-31
Data plays an increasingly important role in sport, from monitoring of fitness of athletes to success statistics in baseball. In football (soccer) the team performance is more important than the performance ...
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Spore killer genomics: elucidating causes and consequences of a fungal meiotic drive element
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Research project from 2015-05-01 to 2020-04-30
The traditional view of the genome is that of a highly coordinated network that has evolved to produce a successful individual. However, the alternative view of the genome as containing intrinsically conflicting ...
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Temporality of permanence –material and socio-spatial practices in African urbanism
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Research project from 2015-09-14 to 2018-05-13
The constructed materiality of African urbanism can be seen in buildings and the urban layout, especially when they aspire to permanence by building in stone. These built environments have mostly been ...
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The Violence Early-Warning System: Building a Scientific Foundation for Conflict Forecasting
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Research project from 2017-01-01 to 2021-12-31
The challenges of preventing, mitigating, and adapting to large-scale political violence are daunting, particularly when violence escalates where it is not expected. Early-warning systems of sufficient ...
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The evolutionary and ecological implications of mito-nuclear epistasis
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Research project from 2015-10-01 to 2017-09-30
The main hypothesis of the proposed research is that, contrary to common and long-standing belief, mitochondrial genetic variation is functional and plays a key role in evolutionary adaptation. I suggest ...
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Towards an Inclusive Common European Framework for Assisted Reproductive Technologies (ART): Queer Transgender Reproduction in the Age of ART.
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Research project from 2017-08-01 to 2019-07-31
The use and regulation of Assisted Reproductive Technologies (ARTs) has undergone repeated significant changes since the 1980s, partly to accommodate biotechnological developments, partly to recognize ...
Showing 28 Of 28 hits
Research spotlight: The coronavirus
New method for discovery of antiviral drugs
2 August 2021. The current COVID-19 pandemic has highlighted the need for methods to identify new or repurposed dru ...
Helpline important for older people during the pandemic
8 July 2021. For many older individuals, the COVID-19 pandemic has resulted in the loss of daily anonymous contac ...
The national COVID-19 Data Portal turns one year old
3 June 2021. The national Swedish COVID-19 Data Portal was launched one year ago to support researchers in utilis ...
Lectures
Uppsala University’s researchers share their knowledge in public lectures. Every year, the University is visited by leading researchers and influential people from around the world. At Uppsala University, you can hear Nobel laureates, researchers, authors, politicians and many others give lectures. Here we present some of the most prominent, annually occurring lectures at Uppsala University.