Research at Uppsala University
History of human antibiotic use written in the oral bacteria of wild brown bears
25 August 2021. An international team of researchers used historical museum collections to study the effects of huma ...
How research can encourage us to cycle instead
19 August 2021. How do you get to work in the mornings? Transport currently accounts for 25 per cent of GHG emission ...
Philippine ethnic group has most Denisovan DNA
13 August 2021. The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relat ...
Search for research projects
Here you will find all research projects at Uppsala University funded by the main Swedish funding bodies. The search feature is based on the SweCRIS database.
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Your choice produced 19 hits
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A pharmacometric framework for model-based translation of antibiotic effects in vitro to outcomes in patients infected by resistant bacteria
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Research project from 2019-01-01 to 2022-12-31
Antibiotic resistance is increasing at an alarming rate. There is consequently an urgent need for new approaches that can define efficient dosing strategies and facilitate development of treatments against ...
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Finding the hidden GEMS in genome-wide association analyses: Do we need to change the way to model the genetics of quantitative traits?
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Research project from 2018-01-01 to 2021-12-31
Genotype-to-phenotype mapping is a core feature of genetics. These maps describe how combinations of DNA variants (genotypes) contribute to the appearance (the phenotype) of an individual organism. Staggering ...
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Computations for structural mass spectrometry
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Research project from 2016-01-01 to 2018-12-31
The structure and dynamics of biomolecules are intimately coupled to biological function, and numerous diseases are rooted in biomolecular structure. Functionally important conformational states are often ...
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Central regulation of food intake and reward; Molecular mechanisms and human pathologies
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Research project from 2017-01-01 to 2019-12-31
We aim to study the molecular mechanisms of food intake and reward functions, considering genetic background and cognitive functions. We plan to combine fly, mouse and human genetic models to unravel modes ...
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Cost-effective genotyping in plant and animal breeding using computational analysis of pooled samples
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Research project from 2018-01-01 to 2020-12-31
Genomic breeding has given proven advances in plant and animal breeding. However, current costs make genotyping of high numbers of individuals, or the application of genomic breeding to local breeds or ...
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Cultural evolution of texts
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Research project from 2020-01-01 to 2023-12-31
How is cultural knowledge passed down through generations? Which processes promotes the fidelity of transmission of written or oral texts over longer or shorter times? And what are the regularities in ...
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DNA sequencing-based microscopy for ultra-multiplexed, optics-free, 3D imaging of proteins and genes
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Research project from 2021-01-01 to 2024-12-31
Last year marked the emergence of DNA sequencing-based microscopy: methods to produce optics-free microscopic images by encoding spatial information in DNA sequence format prior to recovering that information ...
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Dissection of the genetics underlying long-term selection response for immune and production traits
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Research project from 2014-01-01 to 2016-12-31
Genetics has allowed humans to domesticate animals and plants, and through intense breeding develop breeds and varieties with desirable properties for agricultural production across the globe. Despite ...
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ELIXIR -- the European infrastructure for biological information
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Research project from 2017-01-01 to 2017-12-31
The main mission of ELIXIR is to build a sustainable European infrastructure for biological information, supporting life-science research and its translation to society, the bio-industries, environment ...
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From single cells to cancer tumors - multiscale simulation of stochastic multicellular systems
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Research project from 2016-01-01 to 2019-12-31
Detailed stochastic models of single-cell molecular networks have led to important biological insights into diverse cellular phenomena, and computational experiments hold great promise to complement wet ...
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The physics of genetic information processing
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Research project from 2017-01-01 to 2022-12-31
The mechanisms for decoding the genome’s regulatory sequences are far less understood than the mechanisms for encoding the structure and function of the regulated macromolecules. The focus of the environment ...
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The physics of gene regulation in the context of the growing cell
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Research project from 2013-01-01 to 2017-12-31
The main objective is to develop new technology for studying gene regulation at high spatial and temporal resolution in living cells. The methods will be used to answer fundamental questions about how ...
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Gotland in the 3rd millennium BC. Archaeogenetics, archaeology and cultural diversity
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Research project from 2020-01-01 to 2022-12-31
Recent technological advancements have allowed for in-depth genetic investigations of pre-historic humans (archaeogenetics) which have profoundly altered European archaeology. These studies give unique ...
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Integrated analyses of immune repertoires in solid cancers
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Research project from 2020-07-01 to 2022-06-30
Cancer is the second leading cause of death worldwide and even though the last decade has led to several breakthroughs in the molecular characterization of the underlying disease mechanisms there is still ...
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Intelligent evolution of new generation probing technology via massive parallel DNA synthesis and sequencing
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Research project from 2014-01-01 to 2016-12-31
Future medical analysis will require comprehensive and rapid analyses of broad ranges of molecular entities to better define cell states, e.g. stemness, or disease states e.g. cancer signatures. The proposed ...
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Mapping the virus-host transcriptional landscape for a better understanding of dengue disease
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Research project from 2021-01-01 to 2024-12-31
Despite more than 100 million infections annually and extensive scientific efforts to understand disease mechanisms, the clinical course of dengue infection, progression to severe dengue disease, particularly ...
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National Bioinformatics Infrastructure Sweden (NBIS)
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Research project from 2016-04-01 to 2017-12-31
NBIS is a continuation of BILS (Bioinformatics Infrastructure for Life Sciences) now also including WABI (Wallenberg Advanced Bioinformatics Infrastr.), SILS (Systems Biology Infrastr. for Life Sciences ...
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National Bioinformatics Infrastructure Sweden (NBIS) and the Swedish node in Elixir (the European Infrastructure for Biological Information)
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Research project from 2021-01-01 to 2024-12-31
For the period 2021–2024, NBIS plans to continue our activities in providing excellence in bioinformatics support to researchers in Sweden, enabling world-class life science by offering support, infrastructure ...
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National Bioinformatics Infrastucture Sweden (NBIS) and the Swedish node in Elixir (the European infrastructure for biological information)
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Research project from 2018-01-01 to 2020-12-31
NBIS enables world-class life science by providing expert knowledge, creative data integration, advanced training, efficient data publication and access to high-performance data and analysis methods. NBIS ...
Showing 19 Of 19 hits
Research spotlight: The coronavirus
New method for discovery of antiviral drugs
2 August 2021. The current COVID-19 pandemic has highlighted the need for methods to identify new or repurposed dru ...
Helpline important for older people during the pandemic
8 July 2021. For many older individuals, the COVID-19 pandemic has resulted in the loss of daily anonymous contac ...
The national COVID-19 Data Portal turns one year old
3 June 2021. The national Swedish COVID-19 Data Portal was launched one year ago to support researchers in utilis ...
Lectures
Uppsala University’s researchers share their knowledge in public lectures. Every year, the University is visited by leading researchers and influential people from around the world. At Uppsala University, you can hear Nobel laureates, researchers, authors, politicians and many others give lectures. Here we present some of the most prominent, annually occurring lectures at Uppsala University.