Läkemedelssäkerhet & Toxikologi

Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation: Isolation of bromopyrrole alkaloids from Stylissa massa

Kosgahakumbura, Lakmini; Gamage, Jayani; Robertson, Luke; Muhammad, Taj et al.

Ingår i PLOS ONE, 2024

• DOI för Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation: Isolation of bromopyrrole alkaloids from Stylissa massa
• Ladda ner fulltext (pdf) av Screening for antibacterial and cytotoxic activities of Sri Lankan marine sponges through microfractionation: Isolation of bromopyrrole alkaloids from Stylissa massa

Myrcene Attenuates Renal Inflammation and Oxidative Stress in the Adrenalectomized Rat Model

Islam, Azim Ullah Shamsul; Hellman, Björn; Nyberg, Fred; Amir, Naheed et al.

Ingår i Molecules, 2020

• DOI för Myrcene Attenuates Renal Inflammation and Oxidative Stress in the Adrenalectomized Rat Model
• Ladda ner fulltext (pdf) av Myrcene Attenuates Renal Inflammation and Oxidative Stress in the Adrenalectomized Rat Model

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer

Al Shemaili, Jasem; Parekh, Khatija A.; Newman, Robert A.; Hellman, Björn et al.

Ingår i Marine Drugs, 2016

• DOI för Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer
• Ladda ner fulltext (pdf) av Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer

Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Bivehed, Erik; Hellman, Björn; Wenson, Leonie; Stenerlöw, Bo et al.

Ingår i Nucleic Acids Research, 2024

• DOI för Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling
• Ladda ner fulltext (pdf) av Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells

Kahaliw, Wubayehu; Hellman, Björn; Engidawork, Ephrem

Ingår i BMC Complementary and Alternative Medicine, 2018

• DOI för Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells
• Ladda ner fulltext (pdf) av Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells

DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Bivehed, Erik; Hellman, Björn; Fan, Yuting; Haglöf, Jakob et al.

Ingår i Mutation research. Genetic toxicology and environmental mutagenesis, 2023

• DOI för DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
• Ladda ner fulltext (pdf) av DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay

Evaluation of Potential DNA-Damaging Effects of Nitenpyram and Imidacloprid in Human U937-Cells Using a New Statistical Approach to Analyse Comet Data

Bivehed, Erik; Gustafsson, Anton; Berglund, Anders; Hellman, Björn

Ingår i Exposure and Health, s. 547-554, 2020

• DOI för Evaluation of Potential DNA-Damaging Effects of Nitenpyram and Imidacloprid in Human U937-Cells Using a New Statistical Approach to Analyse Comet Data
• Ladda ner fulltext (pdf) av Evaluation of Potential DNA-Damaging Effects of Nitenpyram and Imidacloprid in Human U937-Cells Using a New Statistical Approach to Analyse Comet Data

Flash-comet: Significantly improved speed and sensitivity of the comet assay through the introduction of lithium-based solutions and a more gentle lysis

Bivehed, Erik; Söderberg, Ola; Hellman, Björn

Ingår i Mutation research. Genetic toxicology and environmental mutagenesis, 2020

• DOI för Flash-comet: Significantly improved speed and sensitivity of the comet assay through the introduction of lithium-based solutions and a more gentle lysis

An in vitro Study on the DNA Damaging Effects of Phytochemicals Partially Isolated from an Extract of Glinus lotoides

Demma, Jemal; El-Seedi, Hesham; Engidawork, Ephrem; Aboye, Teshome Leta et al.

Ingår i Phytotherapy Research, s. 507-514, 2013

• DOI för An in vitro Study on the DNA Damaging Effects of Phytochemicals Partially Isolated from an Extract of Glinus lotoides

Low levels of the air pollutant 1-nitropyrene induce DNA damage, increased levels of reactive oxygen species and endoplasmic reticulum stress in human endothelial cells

Andersson, Helén; Piras, Elena; Demma, Jemal; Hellman, Björn et al.

Ingår i Toxicology, s. 57-64, 2009

• DOI för Low levels of the air pollutant 1-nitropyrene induce DNA damage, increased levels of reactive oxygen species and endoplasmic reticulum stress in human endothelial cells

An analysis of Vigimed, a global E-mail system for the exchange of pharmacovigilance information

Johansson, K; Olsson, S; Hellman, Björn; Meyboom, RHB

Ingår i Drug Safety, s. 883-889, 2007

Flash-comet assay

Bivehed, Erik; Hellman, Björn

Ingår i MethodsX, 2020

• DOI för Flash-comet assay
• Ladda ner fulltext (pdf) av Flash-comet assay

In vitro bioanalysis of drinking water from source to tap

Rosenmai, Anna Kjerstine; Lundqvist, Johan; le Godec, Theo; Ohisson, Asa et al.

Ingår i Water Research, s. 272-280, 2018

• DOI för In vitro bioanalysis of drinking water from source to tap

A bioactivity-guided screening of Sri Lankan plants in the search for novel antibacterial and anticancer agents

Mohotti, S.; Rajendran, S.; Muhammad, Taj; Strömstedt, Adam A. et al.

Ingår i Planta Medica, 2016

• DOI för A bioactivity-guided screening of Sri Lankan plants in the search for novel antibacterial and anticancer agents

Evaluation of catechol-induced DNA damage in human lymphocytes: A comparison between freshly isolated lymphocytes and T-lymphocytes from extended-term cultures

Andersson, Maria; Hellman, Björn

Ingår i Toxicology in Vitro, s. 716-722, 2007

• DOI för Evaluation of catechol-induced DNA damage in human lymphocytes: A comparison between freshly isolated lymphocytes and T-lymphocytes from extended-term cultures

Genotoxicity of plumbagin and its effects on catechol and NQNO-induced DNA damage in mouse lymphoma cells

Demma, Jemal; Hallberg, Karl; Hellman, Björn

Ingår i Toxicology in Vitro, s. 266-271, 2009

• DOI för Genotoxicity of plumbagin and its effects on catechol and NQNO-induced DNA damage in mouse lymphoma cells

Potential genotoxicity of plant extracts used in Ethiopian traditional medicine

Demma, Jemal; Engidawork, E; Hellman, Björn

Ingår i Journal of Ethnopharmacology, s. 136-142, 2009

• DOI för Potential genotoxicity of plant extracts used in Ethiopian traditional medicine

Interindividual differences in initial DNA repair capacity when evaluating H2O2-induced DNA damage in extended-term cultures of human lymphocytes using the comet assay

Andersson, Maria; Stenqvist, Per; Hellman, Björn

Ingår i Cell Biology and Toxicology, s. 401-411, 2007

• DOI för Interindividual differences in initial DNA repair capacity when evaluating H2O2-induced DNA damage in extended-term cultures of human lymphocytes using the comet assay

Evaluation of α-tocopherols effect on catechol and o-phenylenediamine induced DNA damage: An in vitro study using two different staining techniques in the comet assay

Åsgård, Rikard; Håkansson, Sofia; Lundin, Rickard; Hellman, Björn

Fungicide prochloraz induces oxidative stress and DNA damage in vitro

Lundqvist, J.; Hellman, Björn; Oskarsson, A.

Ingår i Food and Chemical Toxicology, s. 36-41, 2016

• DOI för Fungicide prochloraz induces oxidative stress and DNA damage in vitro

Genotoxicity and Cellular Uptake of Cyclotides: Evidence for Multiple Mode of Action

Yeshak, Mariamawit Y; Göransson, Ulf; Burman, Robert; Hellman, Björn

Ingår i Mutation research. Genetic toxicology and environmental mutagenesis, s. 176-181, 2012

• DOI för Genotoxicity and Cellular Uptake of Cyclotides: Evidence for Multiple Mode of Action

Effect of beta-carotene on catechol-induced genotoxicity in vitro: Evidence of both enhanced and reduced DNA damage

Åsgård, Rikard; Hellman, Björn

Ingår i Free radical research, s. 692-698, 2013

• DOI för Effect of beta-carotene on catechol-induced genotoxicity in vitro: Evidence of both enhanced and reduced DNA damage

Evidence for different mechanisms of action behind the mutagenic effects of 4-NOPD and OPD: the role of DNA damage, oxidative stress and an imbalanced nucleotide pool

Åsgård, Rikard; Haghdoost, Siamak; Osterman Golkar, Siv; Hellman, Björn et al.

Ingår i Mutagenesis, s. 637-644, 2013

• DOI för Evidence for different mechanisms of action behind the mutagenic effects of 4-NOPD and OPD: the role of DNA damage, oxidative stress and an imbalanced nucleotide pool

Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer

Al Shemaili, Jasem; Mensah-Brown, E.; Parekh, K.; Thomas, S. A. et al.

Ingår i European Journal of Cancer, s. 1391-1398, 2014

• DOI för Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer

Alkaline single cell gel electrophoresis of DNA fragments in biomonitoring for genotoxicity: An introductory study on healthy human volunteers

Hellman, Björn; Vaghef, Hamid; Friis, Lennart; Edling, Christer

Ingår i International Archives of Occupational and Environmental Health, s. 185, 1997

No evidence for a diuretic effect of benzisothiazolinone (BIT) in an experimental animal model employing anaesthetised rats

Hellman, Björn; Sjoquist, Mats; Anundi, Helena; Edling, Christer

Ingår i J Occupational Health, s. 198, 1998

Extended-term cultures of human T-lymphocytes and the comet assay: a useful combination when testing for genotoxicity in vitro?

Andersson, Maria; Agurell, Eva; Vaghef, Hamid; Bolcsfoldi, George et al.

Ingår i Mutation Research, s. 43, 2003

Radiation-induced DNA-damage and gene expression profiles in human lung cancer cells with different radiosensitivity.

Hellman, Björn; Brodin, David; Andersson, Maria; Dahlman-Wright, Karin et al.

Ingår i Exp Oncol, s. 102-7, 2005

Impact of interindividual differences in initial DNA repair capacity when evaluating DNA damage using extended-term cultures of human lymphocytes and the comet assay

Maria, Andersson; Stenqvist, Per; Hellman, Björn

Ingår i Toxicology and applied pharmacology

Extended-term cultures of human T-lymphocytes: a useful combination when testing for genotoxicity in vitro?

Maria, Andersson; Eva, Agurell; Hamid, Vaghef; Bolcsfoldi, George et al.

Ingår i Mutation Research, s. 43-55, 2003

Different roles of Fpg and Endo III on catechol-induced DNA damage in extended-term cultures of human lymphocytes and L5178Y mouse lymphoma cells

Maria, Andersson; Hellman, Björn

Ingår i Toxicology In Vitro, s. 779-786, 2005

Cadmium-induced changes in apoptotic gene expression levels and DNA damage in mouse embryos are blocked by zinc.

Fernández, Estíbaliz L.; Gustafson, Anne-Lee; Andersson, Maria; Hellman, Bjorn et al.

Ingår i Toxicological Sciences, s. 162-170, 2003