Institutionen för farmaci

A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores

Minichmayr, Iris K.; Plan, Elodie L.; Weber, Benjamin; Ueckert, Sebastian

Ingår i Pharmaceutical research, s. 123-135, 2025

• DOI för A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores
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A model-based evaluation of the pharmacokinetics-pharmacodynamics (PKPD) of avibactam in combination with ceftazidime

O'Jeanson, Amaury; Nielsen, Elisabet I.; Friberg, Lena E.

Ingår i JAC - Antimicrobial Resistance, 2025

• DOI för A model-based evaluation of the pharmacokinetics-pharmacodynamics (PKPD) of avibactam in combination with ceftazidime
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An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae

Zhao, Chenyan; van den Berg, Sanne; Wang, Zhigang; Olsson, Anna et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för An integrative and translational PKPD modelling approach to explore the combined effect of polymyxin B and minocycline against Klebsiella pneumoniae
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Analysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification

Dufault, Suzanne M.; Davies, Geraint R.; Svensson, Elin M.; Sloan, Derek J. et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för Analysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification
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Assessing central nervous system drug delivery

Hammarlund-Udenaes, Margareta; Loryan, Irena

Ingår i Expert Opinion on Drug Delivery, s. 421-439, 2025

• DOI för Assessing central nervous system drug delivery
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Cardiovascular events following coronavirus disease 2019 vaccination in adults: a nationwide Swedish study

Xu, Yiyi; Li, Huiqi; Santosa, Ailiana; Wettermark, Björn et al.

Ingår i European Heart Journal, s. 147-157, 2025

• DOI för Cardiovascular events following coronavirus disease 2019 vaccination in adults: a nationwide Swedish study
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Ceftazidime-avibactam (CAZ-AVI) pharmacokinetics in critically ill patients undergoing continuous venovenous hemodiafiltration (CVVHDF)

O'Jeanson, Amaury; Ioannidis, Konstantinos; Nielsen, Elisabet I.; Galani, Lamprini et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för Ceftazidime-avibactam (CAZ-AVI) pharmacokinetics in critically ill patients undergoing continuous venovenous hemodiafiltration (CVVHDF)
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Comparison of ICS dose reduction vs. montelukast discontinuation for step-down therapy in well-controlled asthma: a pilot randomized controlled trial

Rahimi, Besharat; Rad, Niloofar Khoshnam; Amini, Shahideh; Gholamzadeh, Marsa et al.

Ingår i BMC Pulmonary Medicine, 2025

• DOI för Comparison of ICS dose reduction vs. montelukast discontinuation for step-down therapy in well-controlled asthma: a pilot randomized controlled trial
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Comparison of the power and type 1 error of total score models for drug effect detection in clinical trials

Haem, Elham; Karlsson, Mats O.; Ueckert, Sebastian

Ingår i Journal of Pharmacokinetics and Pharmacodynamics, 2025

• DOI för Comparison of the power and type 1 error of total score models for drug effect detection in clinical trials
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Development and validation of a time-varying correction factor for QT interval assessment in drug-resistant tuberculosis patients

Vongjarudech, Thanakorn; Dosne, Anne-Gaelle; Remmerie, Bart; Dooley, Kelly E. et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för Development and validation of a time-varying correction factor for QT interval assessment in drug-resistant tuberculosis patients
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Development and Validation of an Instrument to Assess Quality and Completeness of Medication-Related Discharge Documentation

Bertilsson, Emma; Östman, Victoria; Cam, Henrik; Franzon, Kristin et al.

Ingår i Journal of Evaluation In Clinical Practice, 2025

• DOI för Development and Validation of an Instrument to Assess Quality and Completeness of Medication-Related Discharge Documentation

Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices

Schouten, Wietse M; Van Bocxlaer, Katrien; Rosing, Hilde; Huitema, Alwin D R et al.

Ingår i Journal of chromatography. B, 2025

• DOI för Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices
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Drug utilization among young adults with atopic dermatitis: Influence of sex, socio-economic status and disease severity

Lindström Carmanius, Penny; Lundin, S.; Ödling, M.; Kimland, E. et al.

Ingår i Journal of the European Academy of Dermatology and Venereology, s. 145-153, 2025

• DOI för Drug utilization among young adults with atopic dermatitis: Influence of sex, socio-economic status and disease severity
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Exploring Industry Stakeholder Perspectives on a Clinical Testbed for Evaluating the Handling of Protein Drugs in Hospitals

Arvidsson, Jesper; Alkhatib, Yaser; Egen, Marc; Elofsson, Ulla et al.

Ingår i Journal of Pharmaceutical Sciences, 2025

• DOI för Exploring Industry Stakeholder Perspectives on a Clinical Testbed for Evaluating the Handling of Protein Drugs in Hospitals
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Facilitators and barriers to medication self-management for patients with multiple long-term conditions transitioning from hospital to home

Olsen Syversen, Malin; Glatkauskas, Mikas; Mathiesen, Liv; Lea, Marianne et al.

Ingår i Exploratory Research in Clinical and Social Pharmacy, 2025

• DOI för Facilitators and barriers to medication self-management for patients with multiple long-term conditions transitioning from hospital to home
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Have People Treated With Antihypertensives Been Diagnosed With Hypertension?: A Cross-Sectional Study in Stockholm, Sweden

Treciokiene, Indre; Forslund, Tomas; Kahan, Thomas; Taxis, Katja et al.

Ingår i Pharmacoepidemiology and Drug Safety, 2025

• DOI för Have People Treated With Antihypertensives Been Diagnosed With Hypertension?: A Cross-Sectional Study in Stockholm, Sweden
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Healthcare provision for displaced people in transit: Analyses of routinely collected data from INTERSOS clinics at the Ukrainian border with Moldova and Poland

Aljadeeah, Saleh; Hosseinalipour, Seyed-Moeen; Khanyk, Nataliia; Szocs, Eszter et al.

Ingår i Journal of Migration and Health, 2025

• DOI för Healthcare provision for displaced people in transit: Analyses of routinely collected data from INTERSOS clinics at the Ukrainian border with Moldova and Poland
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How much time do nurses in Norwegian emergency departments spend on different work tasks with and without a clinical pharmacist present: a time and motion study

Holis, Renata Vesela; Garcia, Beate Hennie; Lehnbom, Elin Christina; Fagerli, Marie et al.

Ingår i BMC Emergency Medicine, 2025

• DOI för How much time do nurses in Norwegian emergency departments spend on different work tasks with and without a clinical pharmacist present: a time and motion study
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Identifying critical elements in using question prompt lists at the pharmacy counter to induce patient activation: using principles of conversation analysis

Svensberg, Karin; Kaae, Susanne; Broch Mottelson, Nanna; Ljungberg Persson, Christina

Ingår i Research in Social and Administrative Pharmacy, s. 74-84, 2025

• DOI för Identifying critical elements in using question prompt lists at the pharmacy counter to induce patient activation: using principles of conversation analysis
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Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions

Alhalaweh, Amjad; El Sayed, Mira; Kovac, Lucia; Bergström, Christel A.S.

Ingår i Journal of Pharmaceutical Sciences, s. 458-467, 2025

• DOI för Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
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Initiation of Anticoagulants During the COVID-19 Pandemic in Sweden: An Interrupted Time Series Analysis

Samuelsen, Per-Jostein; Wettermark, Björn; Nyberg, Fredrik; Hajiebrahimi, Mohammadhossein

Ingår i Basic & Clinical Pharmacology & Toxicology, 2025

• DOI för Initiation of Anticoagulants During the COVID-19 Pandemic in Sweden: An Interrupted Time Series Analysis
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Integrated modeling of biomarkers, survival and safety in clinical oncology drug development

Liu, Han; Ibrahim, Eman I.K.; Centanni, Maddalena; Sarr, Céline et al.

Ingår i Advanced Drug Delivery Reviews, 2025

• DOI för Integrated modeling of biomarkers, survival and safety in clinical oncology drug development
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Intervention description of pharmacist-facilitated medication reviews in Nordic primary care settings: a scoping review

Bo, Karl-Erik; Halvorsen, Kjell H.; Lehnbom, Elin C.

Ingår i Scandinavian Journal of Primary Health Care, s. 241-253, 2025

• DOI för Intervention description of pharmacist-facilitated medication reviews in Nordic primary care settings: a scoping review
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Leadership and mentorship of Professor Lynne S. Taylor: A personal account from former mentees

Alhalaweh, Amjad; Indulkar, Anura S.; Mosquera-Giraldo, Laura I.; Purohit, Hitesh S. et al.

Ingår i Journal of Pharmaceutical Sciences, s. 265-268, 2025

• DOI för Leadership and mentorship of Professor Lynne S. Taylor: A personal account from former mentees

Leveraging digital medication adherence technologies to enhance sustainability of European health systems: ENABLE's key recommendations

van Boven, Job F. M.; Dima, Alexandra L.; Wettermark, Björn; Potocnjak, Ines et al.

Ingår i The Lancet Regional Health, 2025

• DOI för Leveraging digital medication adherence technologies to enhance sustainability of European health systems: ENABLE's key recommendations

Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025

• DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration

de la Rosa, Andres; Metzendorf, Nicole G.; Efverström, Jonathan; Godec, Ana et al.

Ingår i Neurotherapeutics, 2025

• DOI för Lowering the affinity of single-chain monovalent BBB shuttle scFc-scFv8D3 prolongs its half-life and increases brain concentration
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Medication adherence in the curricula of future European physicians, pharmacists and nurses: a cross-sectional survey

Gottlieb, Hanna; Seghers, Laura; Leiva-Fernandez, Francisca; Ghiciuc, Cristina Mihaela et al.

Ingår i BMC Medical Education, 2025

• DOI för Medication adherence in the curricula of future European physicians, pharmacists and nurses: a cross-sectional survey
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Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier

Lundquist, Patrik; Hagforsen, Eva; Wagner, Michael; Alimohammadi, Mohammad et al.

Ingår i Biochimica et Biophysica Acta - Molecular Basis of Disease, 2025

• DOI för Mild-to-moderate psoriasis is associated with subclinical inflammation in the duodenum and a tendency of disturbed intestinal barrier
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Model-informed precision dosing of vancomycin in clinical practice: an intervention development study

Swartling, Maria; Hamberg, Anna-Karin; Furebring, Mia; Tängdén, Thomas et al.

Ingår i International Journal of Clinical Pharmacy, s. 178-186, 2025

• DOI för Model-informed precision dosing of vancomycin in clinical practice: an intervention development study
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Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Karamchand, Sumanth; Chipamaunga, Tsungai; Naidoo, Poobalan; Naidoo, Kiolan et al.

Ingår i JMIR Research Protocols, 2025

• DOI för Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial
• Ladda ner fulltext (pdf) av Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Paralemmin-1 controls the nanoarchitecture of the neuronal submembrane cytoskeleton

Macarron-Palacios, Victor; Hubrich, Jasmine; Lima, Maria Augusta do Rego Barros Fernandes; Metzendorf, Nicole G. et al.

Ingår i Science Advances, 2025

• DOI för Paralemmin-1 controls the nanoarchitecture of the neuronal submembrane cytoskeleton
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Plasma effects on bacterial time-kill dynamics: Insights from a PK/PD modelling analysis

Bahnasawy, Salma M.; Ahmed, Hifza; Zeitlinger, Markus; Friberg, Lena E. et al.

Ingår i International Journal of Antimicrobial Agents, 2025

• DOI för Plasma effects on bacterial time-kill dynamics: Insights from a PK/PD modelling analysis
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Pneumatic tube transport of trastuzumab in IV bags -effect of headspace and surfactant on subvisible particle formation

Kjellström, Anna; Cederwall, Ida; Sabaté-Martínez, Clàudia; Kwok, Stanley et al.

Ingår i Journal of Pharmaceutical Sciences, s. 1142-1151, 2025

• DOI för Pneumatic tube transport of trastuzumab in IV bags -effect of headspace and surfactant on subvisible particle formation

Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model

Wilske, Frida; Eriksson, Olof; Amini, Rose-Marie; Estrada, Sergio et al.

Ingår i Intensive Care Medicine Experimental, 2025

• DOI för Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
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Simplifying medicine dosing for children by harmonising weight bands across therapeutic areas

Waalewijn, Hylke; Almett, Mounier; Wasmann, Roeland E.; Cressey, Tim R. et al.

Ingår i The Lancet Child and Adolescent Health, s. 274-282, 2025

• DOI för Simplifying medicine dosing for children by harmonising weight bands across therapeutic areas

Sociodemographic characteristics and health status of women with breast cancer and COVID 19 diagnosis by menopausal status a cross sectional study

Hajiebrahimi, Mohammadhossein; Shihan, Hussam; Bratt, Ola; Li, Huiqi et al.

Ingår i Scientific Reports, 2025

• DOI för Sociodemographic characteristics and health status of women with breast cancer and COVID 19 diagnosis by menopausal status a cross sectional study
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The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project)

Micheli, Laura; Balayssac, David; Busserolles, Jérôme; Dalbos, Cristelle et al.

Ingår i Toxicology, 2025

• DOI för The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project)
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The Development and Validation of a Simple HPLC-UV Method for the Determination of Vancomycin Concentration in Human Plasma and Application in Critically Ill Patients

Aboelezz, Asma; Tesfamariam, Novel Solomon; Kharouba, Maged; Gligoric, Tamara et al.

Ingår i Molecules, 2025

• DOI för The Development and Validation of a Simple HPLC-UV Method for the Determination of Vancomycin Concentration in Human Plasma and Application in Critically Ill Patients
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The importance of getting the dose right in the treatment of tuberculosis

Dudnyk, Andrii; Lutchmun, Wandini; Duarte, Raquel; Lange, Christoph et al.

Ingår i Breathe, 2025

• DOI för The importance of getting the dose right in the treatment of tuberculosis
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A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Mebrahtu, Aman; Laurén, Ida; Veerman, Rosanne; Güclüler Akpinar, Gözde et al.

Ingår i Nature Communications, 2024

• DOI för A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice
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A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils

Petersen, Inga; Godec, Ana; Ranjbarian, Farahnaz; Hofer, Anders et al.

Ingår i PLOS ONE, 2024

• DOI för A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils
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A Cross-Sectional Study Identifying Medication Adherence Technologies (MATech) in Sweden Using Behavior Change Techniques

Ekenberg, Marie; Landin, Fanny; Wettermark, Björn

Ingår i Patient Preference and Adherence, s. 2281-2293, 2024

• DOI för A Cross-Sectional Study Identifying Medication Adherence Technologies (MATech) in Sweden Using Behavior Change Techniques
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A fully automatic tool for development of population pharmacokinetic models

Chen, Xiaomei; Nordgren, Rikard; Belin, Stella; Hamdan, Alzahra et al.

Ingår i CPT, s. 1784-1797, 2024

• DOI för A fully automatic tool for development of population pharmacokinetic models
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A loading dose of clofazimine to rapidly achieve steady-state-like concentrations in patients with nontuberculous mycobacterial disease

Stemkens, Ralf; Lemson, Arthur; Koele, Simon E.; Svensson, Elin M. et al.

Ingår i Journal of Antimicrobial Chemotherapy, s. 3100-3108, 2024

• DOI för A loading dose of clofazimine to rapidly achieve steady-state-like concentrations in patients with nontuberculous mycobacterial disease
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A pharmacometric multistate model for predicting long-term treatment outcomes of patients with pulmonary TB

Lin, Yu-Jou; Zou, Yuanxi; Karlsson, Mats O.; Svensson, Elin

Ingår i Journal of Antimicrobial Chemotherapy, s. 2561-2569, 2024

• DOI för A pharmacometric multistate model for predicting long-term treatment outcomes of patients with pulmonary TB

A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro

Petersen, Inga; Morrison, Jamie I.; Petrovic, Alex; Babic, Neira et al.

Ingår i Scientific Reports, 2024

• DOI för A shorter linker in the bispecific antibody RmAb158-scFv8D3 improves TfR-mediated blood-brain barrier transcytosis in vitro
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Active CNS delivery of oxycodone in healthy and endotoxemic pigs

Bällgren, Frida; Bergfast, Tilda; Ginosyan, Aghavni; Mahajan, Jessica et al.

Ingår i Fluids and Barriers of the CNS, 2024

• DOI för Active CNS delivery of oxycodone in healthy and endotoxemic pigs
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Advancing opioid stewardship in low-middle-income countries: challenges and opportunities

Jadhari, Rojita; Pathak, Nabin; Shrestha, Rajeev; Shrestha, Sunil et al.

Ingår i JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE, 2024

• DOI för Advancing opioid stewardship in low-middle-income countries: challenges and opportunities
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AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1

Díaz-Holguin, Alejandro; Saarinen, Marcus; Vo, Duc Duy; Sturchio, Andrea et al.

Ingår i Science Advances, 2024

• DOI för AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
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