Våra aktuella publikationer

Aggregation behavior of sodium caprate under different pH, concentration, and intestinal fluid conditions: a coarse-grained molecular dynamics study comparing Martini 2 and Martini 3

Akter, Shahina; Bergström, L. Magnus; Hansson, Per; Hossain, Shakhawath et al.

Ingår i Physical Chemistry, Chemical Physics - PCCP, s. 13514-13525, 2026

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• DOI för Aggregation behavior of sodium caprate under different pH, concentration, and intestinal fluid conditions: a coarse-grained molecular dynamics study comparing Martini 2 and Martini 3
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Biomedical applications of nanoparticles made by flame spray pyrolysis

Li, Haipeng; Goudeli, Eirini; Teleki, Alexandra; Sotiriou, Georgios A.

Ingår i Progress in Energy and Combustion Science, 2026

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• DOI för Biomedical applications of nanoparticles made by flame spray pyrolysis
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Coadministration of a crystalline drug compromises supersaturation and membrane transport of an amorphous drug

Alkalla, Noor; Alhalaweh, Amjad; Bergström, Christel; Li, Na et al.

Ingår i International Journal of Pharmaceutics, 2026

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• DOI för Coadministration of a crystalline drug compromises supersaturation and membrane transport of an amorphous drug

Dissolving Microneedles Loaded with Lipid Nanocarriers for Vaginal Delivery of Clotrimazole: In Vitro and Ex Vivo Evaluation

Udayakumar, Paarkavi; Skalko-Basnet, Natasa; Rondahl, Veronica; Cotaquispe, Cristhian Fernando Salas et al.

Ingår i Molecular Pharmaceutics, s. 2611-2625, 2026

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• DOI för Dissolving Microneedles Loaded with Lipid Nanocarriers for Vaginal Delivery of Clotrimazole: In Vitro and Ex Vivo Evaluation
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Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules

Pohlit, Hannah; Li, Lingxiao; Bini, Estela Isabel; Colucci, Dario et al.

Ingår i Journal of Colloid and Interface Science, 2026

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• DOI för Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules
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Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs

Wu, Mingjun; Karlsson, Eva M.; Bergström, Christel

Ingår i AAPS Journal, 2026

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• DOI för Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs
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Flash nanoprecipitation for co-delivery of diagnostic magnetic nanoparticles and anti-inflammatory drugs in polymeric nanocarriers

Pohlit, Hannah; Weber, Alex Eric; Rahman Ansari, Shaquib; del Carmen Suárez-López, Yael et al.

Ingår i Powder Technology, 2026

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• DOI för Flash nanoprecipitation for co-delivery of diagnostic magnetic nanoparticles and anti-inflammatory drugs in polymeric nanocarriers
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Lipid packing contributes to the confinement of caveolae to the plasma membrane

Larsson, Elin; Kabedev, Aleksei; Pace, Hudson; Lindwall, Jakob et al.

Ingår i eLIFE, 2026

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• DOI för Lipid packing contributes to the confinement of caveolae to the plasma membrane
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Machine Learning on Systematically Curated Data Reveals Key Determinants of Magnetic Hyperthermia Performance

Vega-Carrasco, Edgar Régulo; Rahman Ansari, Shaquib; Zhao, Jiaxi; del Carmen Suárez-López, Yael et al.

Ingår i Small, 2026

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• DOI för Machine Learning on Systematically Curated Data Reveals Key Determinants of Magnetic Hyperthermia Performance
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Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Azhand, Pardis et al.

Ingår i Drug Delivery, 2026

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• DOI för Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis
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Molecular dynamics simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms

Altun, Diyar; He, Xiguo; Bergström, Christel A. S.; Hubert, Madlen et al.

Ingår i Colloids and Surfaces B, 2026

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• DOI för Molecular dynamics simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms
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Thermoresponsive Magnetic Hydrogel for Local Thermal Ablation Treatment of Rectal Cancer

Zhang, Yuming; Paraskeva, Christina; Shaffir, Isha; Tjakra, Marco et al.

Ingår i ACS Applied Materials and Interfaces, s. 914-926, 2026

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• DOI för Thermoresponsive Magnetic Hydrogel for Local Thermal Ablation Treatment of Rectal Cancer
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A perspective on the apparent pKa of ionizable lipids in mRNA-LNPs

Simonsen, Jens B.; Larsson, Per

Ingår i Journal of Controlled Release, 2025

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• DOI för A perspective on the apparent pKa of ionizable lipids in mRNA-LNPs

Click chemistry-based bioconjugation of iron oxide nanoparticles

Asad, Shno; Ahl, David; Suárez-López, Yael del Carmen; Erdélyi, Máté et al.

Ingår i Small, 2025

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• DOI för Click chemistry-based bioconjugation of iron oxide nanoparticles
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Electrospun PLGA fibers with calcium phosphate nanoparticles: effects of nanoparticle crystallinity and carbonate content on osteogenic activity

Suárez, Yael; Ramachandran, Reshma Vasantha; Platania, Varvara; Tavernaraki, Nikoleta N. et al.

Ingår i Biomaterials Science, s. 5863-5873, 2025

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• DOI för Electrospun PLGA fibers with calcium phosphate nanoparticles: effects of nanoparticle crystallinity and carbonate content on osteogenic activity
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Flame-made doped iron oxide nanoparticles as tracers for magnetic particle imaging

Ansari, Shaquib Rahman; Imhoff, Eric Daniel; Suárez-López, Yael del Carmen; Melnyk, Andrii et al.

Ingår i Chemistry of Materials, 2025

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• DOI för Flame-made doped iron oxide nanoparticles as tracers for magnetic particle imaging
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Flame-made nanoparticles for magnetic hyperthermia and MRI in colorectal cancer theranostics

Zhang, Yuming; Paraskeva, Christina; Chen, Qianying; Maisuradze, Anano et al.

Ingår i Nanoscale Advances, s. 5284-5299, 2025

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• DOI för Flame-made nanoparticles for magnetic hyperthermia and MRI in colorectal cancer theranostics
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Impact of chemical structure, lipidation and formulation on luminal stability and intestinal absorption of GLP^-1 analogues

Emeh, Prosper; Englund, Maria; Harun, Said; Valencia, Zulma Santisteban et al.

Ingår i Journal of Controlled Release, 2025

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• DOI för Impact of chemical structure, lipidation and formulation on luminal stability and intestinal absorption of GLP^-1 analogues
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Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions

Alhalaweh, Amjad; El Sayed, Mira; Kovac, Lucia; Bergström, Christel A.S.

Ingår i Journal of Pharmaceutical Sciences, s. 458-467, 2025

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• DOI för Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
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Improved estimation of intrinsic solubility of drug-like molecules through multi-task graph transformer

Zhao, Jiaxi; Hermans, Eline; Sepassi, Kia; Tistaert, Christophe et al.

Ingår i Journal of Cheminformatics, 2025

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• DOI för Improved estimation of intrinsic solubility of drug-like molecules through multi-task graph transformer
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Ingår i Journal of Colloid and Interface Science, s. 287-300, 2025

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• DOI för Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus

Tjakra, Marco; Lidayová, Kristína; Avenel, Christophe; Bergström, Christel et al.

Ingår i Journal of Nanobiotechnology, 2025

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• DOI för Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus
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Magnetic microfiber hyperthermia for synergistic antimicrobial activity against methicillin-resistant Staphylococcus aureus

Rahman Ansari, Shaquib; Grimm, Dominique; Ramachandran, Reshma, V; Suárez-López, Yael del Carmen et al.

Ingår i MATERIALS TODAY BIO, 2025

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• DOI för Magnetic microfiber hyperthermia for synergistic antimicrobial activity against methicillin-resistant Staphylococcus aureus

Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems

Tjakra, Marco; Chakrapeesirisuk, Nopdanai; Jacobson, Magdalena; Sellin, Mikael E. et al.

Ingår i Molecular Pharmaceutics, s. 4032-4045, 2025

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• DOI för Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
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Optimizing amorphous multidrug formulations: A particle engineering approach through spray drying

El Sayed, Mira; Alhalaweh, Amjad; Asdagh, Arash; Kovac, Lucia et al.

Ingår i European Journal of Pharmaceutical Sciences, 2025

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• DOI för Optimizing amorphous multidrug formulations: A particle engineering approach through spray drying
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Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach

Kabedev, Aleksei; Højmark Tønning, Mikkel; Teleki, Alexandra; Bauer-Brandl, Annette et al.

Ingår i Colloids and Surfaces B, 2025

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• DOI för Understanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach
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Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

Zhuo, Xuezhi; Foderà, Vito; Larsson, Per; Schaal, Zarah et al.

Ingår i European Journal of Pharmaceutical Sciences, 2024

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• DOI för Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches
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Benefits of combining supersaturating and solubilizing formulations - Is two better than one?

Alvebratt, Caroline; Karlén, Filip; Åhlén, Michelle; Edueng, Khadijah et al.

Ingår i International Journal of Pharmaceutics, 2024

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• DOI för Benefits of combining supersaturating and solubilizing formulations - Is two better than one?

Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Soukarieh, Fadi; Mashabi, Alaa; Richardson, William; Oton, Eduard Vico et al.

Ingår i Journal of Medicinal Chemistry, s. 1008-1023, 2024

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• DOI för Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections
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Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay

Schulzen, Arne; Andreadis, Ioannis I.; Bergström, Christel A. S.; Quodbach, Julian

Ingår i European Journal of Pharmaceutical Sciences, 2024

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• DOI för Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay
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Development of a canine artificial colonic mucus model for drug diffusion studies

Barmpatsalou, Vicky; Tjakra, Marco; Li, Lingxiao; Dubbelboer, Ilse R. et al.

Ingår i European Journal of Pharmaceutical Sciences, 2024

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• DOI för Development of a canine artificial colonic mucus model for drug diffusion studies
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Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations

Parrow, Albin; Kabedev, Aleksei; Larsson, Per; Johansson, Pernilla et al.

Ingår i Journal of Controlled Release, 2024

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• DOI för Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
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Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set

Zhao, Jiaxi; Hermans, Eline; Sepassi, Kia; Tistaert, Christophe et al.

Ingår i Molecular Pharmaceutics, s. 5261-5271, 2024

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• DOI för Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set
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Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics

Sinko, Patrick D.; Parker, Louis; Prahl Wittberg, Lisa; Bergström, Christel A. S.

Ingår i International Journal of Pharmaceutics, 2024

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• DOI för Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics
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Excipient effects on supersaturation, particle size dynamics, and thermodynamic activity of multidrug amorphous formulations

El Sayed, Mira; Alhalaweh, Amjad; Kovac, Lucia; Bergström, Christel A.S.

Ingår i International Journal of Pharmaceutics, 2024

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• DOI för Excipient effects on supersaturation, particle size dynamics, and thermodynamic activity of multidrug amorphous formulations

Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer

Emeh, Prosper; Breitholtz, Katarina; Berg, Staffan; Vedin, Charlotta et al.

Ingår i Molecular Pharmaceutics, s. 313-324, 2024

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• DOI för Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer

Iron oxide nanoparticles for treatment and diagnosis of chronic inflammatory diseases: A systematic review

Rahman Ansari, Shaquib; Mahajan, Jessica; Teleki, Alexandra

Ingår i Wiley Interdisciplinary Reviews, 2024

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• DOI för Iron oxide nanoparticles for treatment and diagnosis of chronic inflammatory diseases: A systematic review
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Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane

Altun, Diyar; Larsson, Per; Bergström, Christel; Hossain, Md Shakhawath

Ingår i Chemistry and Physics of Lipids, 2024

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• DOI för Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane
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Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison

Kabedev, Aleksei; Bergström, Christel A. S.; Larsson, Per

Ingår i Journal of Computer-Aided Molecular Design, 2024

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• DOI för Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison
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Pharmaceutical Quality by Design Approach to Develop High-Performance Nanoparticles for Magnetic Hyperthermia

Rahman Ansari, Shaquib; Suárez-López, Yael del Carmen; Thersleff, Thomas; Häggström, Lennart et al.

Ingår i ACS Nano, s. 15284-15302, 2024

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• DOI för Pharmaceutical Quality by Design Approach to Develop High-Performance Nanoparticles for Magnetic Hyperthermia
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Virtual special issue of Nordic POP: Patient-oriented products

Rosenholm, Jessica M.; Flaten, Goril Eide; Teleki, Alexandra

Ingår i European Journal of Pharmaceutical Sciences, 2024

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• DOI för Virtual special issue of Nordic POP: Patient-oriented products
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Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs

Barmpatsalou, Vicky; Rodler, Agnes; Jacobson, Magdalena; Karlsson, Eva Marie-Louise et al.

Ingår i European Journal of Pharmaceutical Sciences, 2023

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• DOI för Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs
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Evaluation in pig of an intestinal administration device for oral peptide delivery

Berg, Staffan; Uggla, Teresia; Antonsson, Malin; Nunes, Sandro Filipe et al.

Ingår i Journal of Controlled Release, s. 792-801, 2023

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• DOI för Evaluation in pig of an intestinal administration device for oral peptide delivery

Exploring the use of modified in vitro digestion assays for the evaluation of ritonavir loaded solid lipid-based formulations

Andreadis, Ioannis I.; Schulzen, Arne; Quodbach, Julian; Bergström, Christel

Ingår i European Journal of Pharmaceutical Sciences, 2023

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• DOI för Exploring the use of modified in vitro digestion assays for the evaluation of ritonavir loaded solid lipid-based formulations
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Intrinsic lipolysis rate for systematic design of lipid-based formulations

Jacobsen, Ann-Christin; Kabedev, Aleksei; Sinko, Patrick D.; Palm, Johan E. et al.

Ingår i Drug Delivery and Translational Research, s. 1288-1304, 2023

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• DOI för Intrinsic lipolysis rate for systematic design of lipid-based formulations
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Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications

Saladino, Giovanni Marco; Kakadiya, Ronak; Ansari, Shaquib Rahman; Teleki, Alexandra et al.

Ingår i Nanoscale Advances, s. 1323-1330, 2023

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• DOI för Magnetoresponsive fluorescent core-shell nanoclusters for biomedical applications
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Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs

Parrow, Albin; Larsson, Per; Augustijns, Patrick; Bergström, Christel A. S.

Ingår i Molecular Pharmaceutics, s. 451-460, 2023

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• DOI för Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs
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Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer

Naranjani, Benyamin; Sinko, Patrick D.; Bergström, Christel; Gogoll, A et al.

Ingår i International Journal of Biological Macromolecules, 2023

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• DOI för Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
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Quality attributes for printable emulsion gels and 3D-printed tablets: Towards production of personalized dosage forms

Johannesson, Jenny; Wu, Mingjun; Johansson, Mathias; Bergström, Christel

Ingår i International Journal of Pharmaceutics, 2023

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• DOI för Quality attributes for printable emulsion gels and 3D-printed tablets: Towards production of personalized dosage forms

Revealing the interaction between peptide drugs and permeation enhancers in the presence of intestinal bile salts

Hossain, Md Shakhawath; Kneiszl, Rosita C.; Larsson, Per

Ingår i Nanoscale, s. 19180-19195, 2023

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• DOI för Revealing the interaction between peptide drugs and permeation enhancers in the presence of intestinal bile salts
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