Cardiology

Cardiovascular disease is the most common cause of death and has the highest costs for drug treatment in Sweden. For more than 25 years, the Cardiology research group has been a national centre for research and development in coronary artery disease and its complications, and in recent years stroke prevention during atrial fibrillation.
Description of our research
The research includes register based studies, cell biology research and large clinical trials with patients and healthy controls from many countries.
We aim to improve the treatment and management for the individual patient. We work in the following areas:
- Disease prevalence and mechanisms of disease throughepidemiologic studies of registries and cohort and pathophysiology studies.
- Diagnosis, risk assessment and precision medicine through biomarker studies and studies on imaging based diagnosis.
- Assessment of old (and new) therapies through international clinical trials, independent registry based randomized clinical trials as well as observational registry- and cohort studies.
- Implementation of new therapies through observational registry studies.
Group members
Publications
Part of JACC Cardiovascular Imaging, p. 696-706, 2025
Part of Journal of the American Heart Association, 2025
- DOI for Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
- Download full text (pdf) of Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
Implications of a new clinical classification of acute myocardial infarction
Part of European Heart Journal, p. 131-141, 2025
- DOI for Implications of a new clinical classification of acute myocardial infarction
- Download full text (pdf) of Implications of a new clinical classification of acute myocardial infarction
Part of Trials, 2025
- DOI for Large simple randomized controlled trials – from drugs to medical devices: lessons from recent experience
- Download full text (pdf) of Large simple randomized controlled trials – from drugs to medical devices: lessons from recent experience
Part of European Heart Journal Open, 2025
- DOI for Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in EHJ Open 2024
- Download full text (pdf) of Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in EHJ Open 2024
Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
Part of npj Vaccines, 2025
- DOI for Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
- Download full text (pdf) of Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
Part of Clinical Chemistry, p. 599-608, 2025
- DOI for Cardiac Troponin I and T Ratio and Risk of Cardiovascular or Non-Cardiovascular Events in a General Population
- Download full text (pdf) of Cardiac Troponin I and T Ratio and Risk of Cardiovascular or Non-Cardiovascular Events in a General Population
Part of Upsala Journal of Medical Sciences, 2025
- DOI for Transcatheter aortic valve implantation in Uppsala University Hospital 2009-2023: outcomes and temporal trends
- Download full text (pdf) of Transcatheter aortic valve implantation in Uppsala University Hospital 2009-2023: outcomes and temporal trends
Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
Part of PLOS ONE, 2025
- DOI for Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
- Download full text (pdf) of Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
Part of JACC, p. 853-862, 2025
- DOI for Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest
- Download full text (pdf) of Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest
Part of Journal of the American College of Cardiology, p. 2011-2024, 2025
Part of IJC Heart & Vasculature, 2025
- DOI for Antiarrhythmic drug use in atrial fibrillation among different European countries - as determined by a physician survey
- Download full text (pdf) of Antiarrhythmic drug use in atrial fibrillation among different European countries - as determined by a physician survey
Part of JACC, p. 1217-1228, 2025
Part of Scandinavian Cardiovascular Journal, 2025
- DOI for Autopsy results and factors associated with sudden cardiac death in young individuals with congenital heart disease - a nationwide study
- Download full text (pdf) of Autopsy results and factors associated with sudden cardiac death in young individuals with congenital heart disease - a nationwide study
Part of International Journal of Cardiology, 2025
- DOI for Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
- Download full text (pdf) of Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
Part of European Journal of Cardiovascular Nursing, p. 253-263, 2025
- DOI for Associations between cardiac rehabilitation structure and processes and dietary habits after myocardial infarction: a nationwide registry study
- Download full text (pdf) of Associations between cardiac rehabilitation structure and processes and dietary habits after myocardial infarction: a nationwide registry study
Part of European Heart Journal, p. 183-188, 2025
β-blockers after MI: does ABYSS confirm REDUCEd use after all?
Part of Nature Reviews Cardiology, p. 7-8, 2025
Part of American Heart Journal, p. 66-74, 2025
- DOI for HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction (HELP-MI SWEDEHEART): Design and rationale of a cluster randomized, crossover, registry-based clinical trial
- Download full text (pdf) of HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction (HELP-MI SWEDEHEART): Design and rationale of a cluster randomized, crossover, registry-based clinical trial
The ESC Scientific Documents Committee: purposes and achievements
Part of European Heart Journal, p. 1178-1180, 2025
Part of American Heart Journal, p. 17-27, 2025
- DOI for Effect of once-weekly subcutaneous semaglutide on arterial inflammation in people with type 2 diabetes and cardiovascular disease using PET-MRI: Primary results of a randomized, double-blind, placebo-controlled trial
- Download full text (pdf) of Effect of once-weekly subcutaneous semaglutide on arterial inflammation in people with type 2 diabetes and cardiovascular disease using PET-MRI: Primary results of a randomized, double-blind, placebo-controlled trial
2024 EACTS Guidelines on perioperative medication in adult cardiac surgery
Part of European Journal of Cardio-Thoracic Surgery, 2025
A randomized controlled trial of beta-blockers effects on cardiac anxiety
Part of General Hospital Psychiatry, p. 26-32, 2025
- DOI for A randomized controlled trial of beta-blockers effects on cardiac anxiety
- Download full text (pdf) of A randomized controlled trial of beta-blockers effects on cardiac anxiety
Part of American Heart Journal, p. 149-158, 2025
- DOI for Data quality assessment in the SWEDEHEART registry: Insights from serial audits on completeness and accuracy
- Download full text (pdf) of Data quality assessment in the SWEDEHEART registry: Insights from serial audits on completeness and accuracy
Part of Journal of the American College of Cardiology, p. 1550-1564, 2025
- DOI for Early Ezetimibe Initiation After Myocardial Infarction Protects Against Later Cardiovascular Outcomes in the SWEDEHEART Registry
- Download full text (pdf) of Early Ezetimibe Initiation After Myocardial Infarction Protects Against Later Cardiovascular Outcomes in the SWEDEHEART Registry
Revascularization Strategies in ST-Segment Elevation Myocardial Infarction With Multivessel Disease
Part of JACC, p. 1246-1259, 2025
Part of IJC Heart & Vasculature, 2025
- DOI for Comparative outcomes of transcatheter aortic valve replacement in bicuspid vs. tricuspid aortic valve stenosis patients: insights from the SWEDEHEART registry
- Download full text (pdf) of Comparative outcomes of transcatheter aortic valve replacement in bicuspid vs. tricuspid aortic valve stenosis patients: insights from the SWEDEHEART registry
Reinterventions in patients with congenital aortic stenosis and a commissurotomy
Part of Open heart, 2025
- DOI for Reinterventions in patients with congenital aortic stenosis and a commissurotomy
- Download full text (pdf) of Reinterventions in patients with congenital aortic stenosis and a commissurotomy
Part of Circulation. Cardiovascular Quality and Outcomes, 2025
Part of Circulation, 2025
Part of PLOS ONE, 2025
- DOI for Adherence to secondary preventive treatment following myocardial infarction with and without obstructive coronary artery disease
- Download full text (pdf) of Adherence to secondary preventive treatment following myocardial infarction with and without obstructive coronary artery disease
Part of PLOS ONE, 2025
- DOI for Impact of persistence to secondary preventive medication on prognosis for patients with myocardial infarction with and without obstructive coronary arteries
- Download full text (pdf) of Impact of persistence to secondary preventive medication on prognosis for patients with myocardial infarction with and without obstructive coronary arteries
Part of Journal of Clinical Periodontology, p. 16-23, 2025
- DOI for Does Periodontitis Increase the Risk for Future Cardiovascular Events? Long-Term Follow-Up of the PAROKRANK Study
- Download full text (pdf) of Does Periodontitis Increase the Risk for Future Cardiovascular Events? Long-Term Follow-Up of the PAROKRANK Study
Part of BMJ Open, 2025
- DOI for Prevalence of microspirometry-detected chronic obstructive pulmonary disease in two European cohorts of patients hospitalised for acute myocardial infarction: a cross-sectional study
- Download full text (pdf) of Prevalence of microspirometry-detected chronic obstructive pulmonary disease in two European cohorts of patients hospitalised for acute myocardial infarction: a cross-sectional study
Asundexian versus Apixaban in Patients with Atrial Fibrillation
Part of New England Journal of Medicine, p. 23-32, 2025
Part of JACC-ADVANCES, 2025
- DOI for Prevalence and Impact of Obesity in Patients With Diabetes and Myocardial Infarction A SWEDEHEART Registry Report
- Download full text (pdf) of Prevalence and Impact of Obesity in Patients With Diabetes and Myocardial Infarction A SWEDEHEART Registry Report
Part of Journal of the American College of Cardiology, p. 1471-1484, 2025
No-touch vein grafts in coronary artery bypass surgery: a registry-based randomized clinical trial
Part of European Heart Journal, p. 1720-1729, 2025
- DOI for No-touch vein grafts in coronary artery bypass surgery: a registry-based randomized clinical trial
- Download full text (pdf) of No-touch vein grafts in coronary artery bypass surgery: a registry-based randomized clinical trial
Part of Circulation, p. 1767-1779, 2025
Biomarker-Based Model for Prediction of Ischemic Stroke in Patients With Atrial Fibrillation
Part of Journal of the American College of Cardiology, 2025
Part of Circulation, p. 288-298, 2025
- DOI for Conduction Disturbances and Outcome After Surgical Aortic Valve Replacement in Patients With Bicuspid and Tricuspid Aortic Stenosis
- Download full text (pdf) of Conduction Disturbances and Outcome After Surgical Aortic Valve Replacement in Patients With Bicuspid and Tricuspid Aortic Stenosis
Mosaic loss of Y chromosome and mortality after coronary angiography
Part of European Heart Journal, p. 1603-1616, 2025
- DOI for Mosaic loss of Y chromosome and mortality after coronary angiography
- Download full text (pdf) of Mosaic loss of Y chromosome and mortality after coronary angiography
Part of Scandinavian Cardiovascular Journal, 2025
- DOI for Physical activity levels and associated biopsychosocial characteristics among attendees to exercise-based cardiac rehabilitation
- Download full text (pdf) of Physical activity levels and associated biopsychosocial characteristics among attendees to exercise-based cardiac rehabilitation
Part of BMJ Open, 2025
- DOI for Completion of registration of risk factor variables during telephone vs on-site follow-up after myocardial infarction: a nationwide observational study in 101 199 patients from contemporary clinical practice in Sweden
- Download full text (pdf) of Completion of registration of risk factor variables during telephone vs on-site follow-up after myocardial infarction: a nationwide observational study in 101 199 patients from contemporary clinical practice in Sweden
Part of Journal of Cardiovascular Nursing, 2024
- DOI for Emotional Distress in Younger (<55 Years) and Older (≥55) Patients After a First-Time Myocardial Infarction and Its Prospective Associations With Working Status and Secondary Preventive Goals Among the Younger Cohort
- Download full text (pdf) of Emotional Distress in Younger (<55 Years) and Older (≥55) Patients After a First-Time Myocardial Infarction and Its Prospective Associations With Working Status and Secondary Preventive Goals Among the Younger Cohort
Ischemic Stroke in Adults With Congenital Heart Disease: Cumulative Incidence and Associated Factors
Part of Journal of the American Heart Association, 2024
Neurofilament Light Chain and Risk of Stroke in Patients With Atrial Fibrillation
Part of Circulation, p. 1090-1100, 2024
Symptoms during pregnancy in primiparous women with congenital heart disease
Part of Scandinavian Cardiovascular Journal, 2024
- DOI for Symptoms during pregnancy in primiparous women with congenital heart disease
- Download full text (pdf) of Symptoms during pregnancy in primiparous women with congenital heart disease
Unwrapping phase contrast MRI by iterative graph cuts
Part of Magnetic Resonance in Medicine, p. 1484-1495, 2024
Part of Journal of the American Heart Association, 2024
- DOI for Self-Report Tool for Identification of Individuals With Coronary Atherosclerosis: The Swedish CardioPulmonary BioImage Study
- Download full text (pdf) of Self-Report Tool for Identification of Individuals With Coronary Atherosclerosis: The Swedish CardioPulmonary BioImage Study