Cardiology

Cardiovascular disease is the most common cause of death and has the highest costs for drug treatment in Sweden. For more than 25 years, the Cardiology research group has been a national centre for research and development in coronary artery disease and its complications, and in recent years stroke prevention during atrial fibrillation.
Description of our research
The research includes register based studies, cell biology research and large clinical trials with patients and healthy controls from many countries.
We aim to improve the treatment and management for the individual patient. We work in the following areas:
- Disease prevalence and mechanisms of disease throughepidemiologic studies of registries and cohort and pathophysiology studies.
- Diagnosis, risk assessment and precision medicine through biomarker studies and studies on imaging based diagnosis.
- Assessment of old (and new) therapies through international clinical trials, independent registry based randomized clinical trials as well as observational registry- and cohort studies.
- Implementation of new therapies through observational registry studies.
Group members
Publications
Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
Part of JACC: Advances, 2026
- DOI for Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
- Download full text (pdf) of Standardized Mortality Ratio and Long-Term Stroke Incidence After PFO Closure: A Register Study
Predictors of depressed left-ventricular ejection fraction after acute myocardial infarction
Part of International Journal of Cardiology, 2026
- DOI for Predictors of depressed left-ventricular ejection fraction after acute myocardial infarction
- Download full text (pdf) of Predictors of depressed left-ventricular ejection fraction after acute myocardial infarction
Part of Journal of Hypertension, p. 346-353, 2026
- DOI for Systolic inter-arm blood pressure difference and subclinical atherosclerosis: a population-based cohort study of 29 921 individuals
- Download full text (pdf) of Systolic inter-arm blood pressure difference and subclinical atherosclerosis: a population-based cohort study of 29 921 individuals
Part of Clinical Biochemistry, 2026
- DOI for Change in cardiac troponin T to differentiate acute from chronic myocardial injury in the Emergency Department.
- Download full text (pdf) of Change in cardiac troponin T to differentiate acute from chronic myocardial injury in the Emergency Department.
Part of International Journal of Cardiology, 2026
- DOI for Person-centred care in congenital heart disease: Intercountry variation in patient-reported experiences across 32 countries.
- Download full text (pdf) of Person-centred care in congenital heart disease: Intercountry variation in patient-reported experiences across 32 countries.
Different eGFR markers and prediction of cardiovascular risk.
Part of Journal of Internal Medicine, p. 143-157, 2026
Part of The Lancet Regional Health, 2026
- DOI for Percutaneous and surgical management of aortic stenosis in the SWEDEHEART registry (2013-2023): a nationwide observational study.
- Download full text (pdf) of Percutaneous and surgical management of aortic stenosis in the SWEDEHEART registry (2013-2023): a nationwide observational study.
Part of The Lancet Regional Health, 2026
- DOI for Long-acting nitrate use before and after revascularization to evaluate angina in chronic coronary syndrome: a case-crossover study from SCAAR
- Download full text (pdf) of Long-acting nitrate use before and after revascularization to evaluate angina in chronic coronary syndrome: a case-crossover study from SCAAR
Part of Research Involvement and Engagement, 2025
- DOI for Involving people with lived experiences in the study of a behavioral stress-recovery e-intervention for myocardial infarction patients younger than 55 with cardiac distress: a study protocol.
- Download full text (pdf) of Involving people with lived experiences in the study of a behavioral stress-recovery e-intervention for myocardial infarction patients younger than 55 with cardiac distress: a study protocol.
Part of Arteriosclerosis, Thrombosis and Vascular Biology, 2025
Part of Canadian Journal of Cardiology, 2025
Part of JACC Cardiovascular Imaging, p. 696-706, 2025
Part of Open heart, 2025
- DOI for Anticoagulation and antiplatelet strategies used in Sweden in patients with myocardial infarction and concomitant atrial fibrillation: nationwide cohort study
- Download full text (pdf) of Anticoagulation and antiplatelet strategies used in Sweden in patients with myocardial infarction and concomitant atrial fibrillation: nationwide cohort study
Part of Journal of the American Heart Association, 2025
- DOI for Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
- Download full text (pdf) of Neuroglial Biomarkers for Risk Assessment of Ischemic Stroke and Other Cardiovascular Events in Patients with Atrial Fibrillation Not Receiving Oral Anticoagulation
Coronary Computed Tomography Angiography in Prediction of First Coronary Events.
Part of Journal of the American Medical Association (JAMA), 2025
Part of Heart, p. 1124-1134, 2025
Part of European Heart Journal - Quality of Care and Clinical Outcomes, p. 900-909, 2025
Part of JACC. Advances, p. 101821, 2025
Implications of a new clinical classification of acute myocardial infarction
Part of European Heart Journal, p. 131-141, 2025
- DOI for Implications of a new clinical classification of acute myocardial infarction
- Download full text (pdf) of Implications of a new clinical classification of acute myocardial infarction
Part of Trials, 2025
- DOI for Large simple randomized controlled trials – from drugs to medical devices: lessons from recent experience
- Download full text (pdf) of Large simple randomized controlled trials – from drugs to medical devices: lessons from recent experience
Correction: Large simple randomized controlled trials-from drugs to medical devices
Part of Trials, p. 80, 2025
Part of European Heart Journal, 2025
Part of European Heart Journal, p. 1965-1978, 2025
Part of European Heart Journal Open, 2025
- DOI for Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in EHJ Open 2024
- Download full text (pdf) of Intervention, improved prevention, imaging, inflammation, and innovation: the five I's cardiovascular highlights in EHJ Open 2024
Part of JACC, p. 1557-1568, 2025
Part of BMJ Open, 2025
Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
Part of npj Vaccines, 2025
- DOI for Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
- Download full text (pdf) of Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
High-sensitivity point-of-care measurement of cardiac troponin.
Part of European Heart Journal, 2025
Disrupting the Status Quo: Reimagining How We Use Troponin for Diagnosing Myocardial Infarction
Part of Circulation. Cardiovascular Quality and Outcomes, 2025
Part of Clinical Chemistry, p. 599-608, 2025
- DOI for Cardiac Troponin I and T Ratio and Risk of Cardiovascular or Non-Cardiovascular Events in a General Population
- Download full text (pdf) of Cardiac Troponin I and T Ratio and Risk of Cardiovascular or Non-Cardiovascular Events in a General Population
Part of Upsala Journal of Medical Sciences, 2025
- DOI for Transcatheter aortic valve implantation in Uppsala University Hospital 2009-2023: outcomes and temporal trends
- Download full text (pdf) of Transcatheter aortic valve implantation in Uppsala University Hospital 2009-2023: outcomes and temporal trends
Part of The Lancet, p. 43-51, 2025
- DOI for Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST)
- Download full text (pdf) of Collaboration on the optimal timing of anticoagulation after ischaemic stroke and atrial fibrillation: a systematic review and prospective individual participant data meta-analysis of randomised controlled trials (CATALYST)
Part of Läkartidningen, 2025
Risk Stratification in Acute Myocardial Infarction: From Triage Decision to Outcome Prediction.
Part of European Heart Journal, 2025
GWAS and Replication Analysis of Apparent Treatment-Resistant Hypertension.
Part of Hypertension, 2025
Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
Part of PLOS ONE, 2025
- DOI for Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
- Download full text (pdf) of Associations between physical activity and CVD-related metabolomic and proteomic biomarkers
Part of JACC, p. 853-862, 2025
- DOI for Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest
- Download full text (pdf) of Cangrelor During Percutaneous Coronary Intervention in Patients With Cardiogenic Shock or Cardiac Arrest
Part of Diabetes, obesity and metabolism, 2025
Part of ESC Heart Failure, 2025
- DOI for Cardiometabolic outcomes with dapagliflozin after myocardial infarction by baseline ejection fraction: DAPA-MI
- Download full text (pdf) of Cardiometabolic outcomes with dapagliflozin after myocardial infarction by baseline ejection fraction: DAPA-MI
Part of Journal of the American College of Cardiology, p. 2011-2024, 2025
Part of The Lancet, p. 1103-1114, 2025
Part of IJC Heart & Vasculature, 2025
- DOI for Antiarrhythmic drug use in atrial fibrillation among different European countries - as determined by a physician survey
- Download full text (pdf) of Antiarrhythmic drug use in atrial fibrillation among different European countries - as determined by a physician survey
PASCAL Edge-to-Edge Repair in Atrial and Ventricular Secondary Mitral Regurgitation
Part of JACC, p. 2033-2035, 2025
Atrial functional mitral regurgitation: definition, features, and unknowns.
Part of Clinical Research in Cardiology, 2025
Is This the Last Word of the Diastology Epic?
Part of JACC Cardiovascular Imaging, 2025
Part of The Lancet Regional Health, 2025
- DOI for Recommended methodologies for clinical investigations of high-risk medical devices-Conclusions from the European Union CORE-MD Project
- Download full text (pdf) of Recommended methodologies for clinical investigations of high-risk medical devices-Conclusions from the European Union CORE-MD Project
Part of JACC, p. 1217-1228, 2025
Part of Scandinavian Cardiovascular Journal, 2025
- DOI for Autopsy results and factors associated with sudden cardiac death in young individuals with congenital heart disease - a nationwide study
- Download full text (pdf) of Autopsy results and factors associated with sudden cardiac death in young individuals with congenital heart disease - a nationwide study
Part of Cardiovascular Diabetology, p. 403, 2025
Part of European Heart Journal, Supplement, 2025