Respiratory-, Allergy- and Sleep Research

Asthma, allergy, chronic obstructive pulmonary disease (COPD) and sleep apnea are diseases with a high prevalence and a high impact on public health. In our research we investigate how the environment influences asthma and allergy and the relationship between obesity related diseases such as asthma, gastroesophageal reflux, diabetes and sleep apnea. Another aim is to improve the prognosis in COPD by investigating the impact of physical exercise and nutrition.
Description of our research
Asthma is one of the most common diseases in our modern society. Increased knowledge about the impact of environmental factors like smoking and indoor air pollution may make it possible to prevent and decrease the prevalence of asthma.
Obesity is on the rise in our society. Increased knowledge on how different obesity related diseases such as asthma, reflux, sleep apnea and diabetes are related increases the possibility of optimal treatment in patients with more than one obesity related disease.
The prevalence of COPD is increasing. At present no pharmacological intervention has a proven effect on the prognosis of COPD. If it is possible to demonstrate that physical exercise training in combination with nutritional treatment, and in selected patients oxygen, improves quality of life and reduces hospitalisations large benefits will be achieved both from a patient and society perspective.
Group members
Publications
Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
Part of Journal of Allergy and Clinical Immunology, p. 1310-1320, 2025
- DOI for Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
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Part of The International Journal of Chronic Obstructive Pulmonary Disease, p. 273-286, 2025
- DOI for Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways
- Download full text (pdf) of Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways
Part of Journal of Steroid Biochemistry and Molecular Biology, p. 106879, 2025
Part of Molecular Cancer, 2025
- DOI for Advancing CAR-based cell therapies for solid tumours: challenges, therapeutic strategies, and perspectives
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Prevalence and Clinical Characteristics of Persistent Airflow Limitation in the NOVELTY Cohort.
Part of Annals of the American Thoracic Society, 2025
Part of Respiratory Medicine, 2025
- DOI for A lung function threshold for survival?: FEV1Q and mortality in patients with COPD and chronic respiratory failure
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Part of European Child and Adolescent Psychiatry, p. 1649-1659, 2025
- DOI for Adult mental health outcomes of adolescent depression and co-occurring alcohol use disorder: a longitudinal cohort study
- Download full text (pdf) of Adult mental health outcomes of adolescent depression and co-occurring alcohol use disorder: a longitudinal cohort study
Part of Translational Lung Cancer Research, p. 1972-1985, 2025
- DOI for Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study
- Download full text (pdf) of Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study
Part of European Respiratory Journal, 2025
Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
Part of Pulmonology, 2025
- DOI for Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
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SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
Part of Microorganisms, 2025
- DOI for SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
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Part of Heart Rhythm, 2025
Part of Allergy. European Journal of Allergy and Clinical Immunology, 2025
Part of Clinical Science, p. 449-462, 2025
- DOI for Serum proteomics links the cardiorespiratory biomarkers CTRC, OSM, and MMP-10 to exacerbation severity and number in patients with COPD
- Download full text (pdf) of Serum proteomics links the cardiorespiratory biomarkers CTRC, OSM, and MMP-10 to exacerbation severity and number in patients with COPD
Part of Scientific Reports, 2025
- DOI for The association between systemic inflammation, lung function and respiratory symptoms in the BOLD study in Northern Europe
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The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study
Part of ERJ Open Research, 2025
- DOI for The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study
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Part of Sleep Medicine, 2025
- DOI for Self-reported witnessed episodes of apnea during sleep is associated with incident lung and breast cancer
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Part of Journal of Geriatric Oncology, 2025
- DOI for Effect of preoperative exercise on postoperative complications after colorectal cancer surgery in older people with low physical fitness: The CANOPTIPHYS randomised controlled trial
- Download full text (pdf) of Effect of preoperative exercise on postoperative complications after colorectal cancer surgery in older people with low physical fitness: The CANOPTIPHYS randomised controlled trial
Part of Journal of Sleep Research, 2025
- DOI for Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea: A randomized controlled trial
- Download full text (pdf) of Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea: A randomized controlled trial
Part of BMC Cancer, 2025
- DOI for The hidden impact: social isolation and inflammation's role in pancreatic cancer risk among those with diabetes
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Part of Environmental Health Insights, 2025
- DOI for Assessing the Knowledge and Experience of Healthcare Workers in Zoonoses and the One Health Approach: A Cross-Sectional Study in Ghana
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Part of European Journal of Pediatrics, 2025
Part of Annals of the American Thoracic Society, p. 422-429, 2025
Impact of interstitial lung disease on COVID-19 severity: A nationwide register study
Part of Respiratory Medicine, 2025
- DOI for Impact of interstitial lung disease on COVID-19 severity: A nationwide register study
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Part of Respiratory Medicine, 2025
- DOI for Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD: A cross-sectional study
- Download full text (pdf) of Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD: A cross-sectional study
Clinical phenotypes predict exacerbations of COPD: the TIE cohort study
Part of Respiratory Medicine, 2025
- DOI for Clinical phenotypes predict exacerbations of COPD: the TIE cohort study
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Part of Thorax, 2025
Postexercise Airway Responses by Spirometry and Oscillometry in Nonathlete and Athlete Adolescents
Part of Pediatric Pulmonology, 2025
Part of BMJ Open, 2025
- DOI for Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
- Download full text (pdf) of Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
Part of International Journal for Equity in Health, 2025
- DOI for No socioeconomic disparities in the availability of personal care assistance: a population-based cohort analysis of children living with respiratory support
- Download full text (pdf) of No socioeconomic disparities in the availability of personal care assistance: a population-based cohort analysis of children living with respiratory support
Peripheral airway function and disease burden in COPD
Part of ERJ Open Research, 2025
- DOI for Peripheral airway function and disease burden in COPD
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Low-grade systemic inflammation and peripheral airway function
Part of ERJ Open Research, 2025
- DOI for Low-grade systemic inflammation and peripheral airway function
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Part of International Journal of Cardiology, 2025
- DOI for Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
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Part of Journal of Women's Health, p. 635-643, 2025
Type 2 inflammation and cardiometabolic disease in middle-aged adults
Part of ERJ Open Research, 2025
- DOI for Type 2 inflammation and cardiometabolic disease in middle-aged adults
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Part of Journal of Oral Rehabilitation, p. 367-374, 2025
- DOI for Sleep-Disordered Breathing and Dimensions of The Maxillary Dental Arch and Hard Palate in Children With Class II and Large Overjet-A Case-Control Study
- Download full text (pdf) of Sleep-Disordered Breathing and Dimensions of The Maxillary Dental Arch and Hard Palate in Children With Class II and Large Overjet-A Case-Control Study
Mortality in Severe Asthma - results from the NORDSTAR cohort.
Part of European Respiratory Journal, 2025
Evaluation of recently proposed thresholds to define spirometry bronchodilator response
Part of ERJ Open Research, 2025
Genetically Determined Inflammation-Related Proteins in Asthma and Type-2 Signatures
Part of Allergy. European Journal of Allergy and Clinical Immunology, p. 1702-1714, 2025
- DOI for Genetically Determined Inflammation-Related Proteins in Asthma and Type-2 Signatures
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Occupational exposures to inorganic dust are associated with emphysema: the SCAPIS cohort.
Part of Occupational and Environmental Medicine, p. 437-443, 2025
Estimating the financial burden of asthma among young adults in Sweden
Part of European Clinical Respiratory Journal, 2025
- DOI for Estimating the financial burden of asthma among young adults in Sweden
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Exhaled nitric oxide stability over two years in relation to COPD outcomes
Part of Journal of Breath Research, 2025
- DOI for Exhaled nitric oxide stability over two years in relation to COPD outcomes
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Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY
Part of Pragmatic and Observational Research, p. 135-145, 2025
- DOI for Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY
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How to reduce carbon footprints in asthma
Part of ERJ Open Research, 2025
Part of Läkartidningen, 2025
Switching to the Dry Powder Inhaler: Disease Control with a Lower Carbon Footprint.
Part of Pulmonary therapy, 2025
Part of BMJ Open Respiratory Research, 2025
- DOI for Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study
- Download full text (pdf) of Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study
How to move towards more sustainable asthma care in Europe: an expert opinion paper
Part of Breathe, 2025
Part of Pediatric Pulmonology, 2025
- DOI for Nasal Nitric Oxide Measurements During Tidal Breathing: A Device Comparison Study in Ciliary Disease.
- Download full text (pdf) of Nasal Nitric Oxide Measurements During Tidal Breathing: A Device Comparison Study in Ciliary Disease.
Part of Thorax, p. 378-384, 2025