Lung-, allergi- och sömnforskning

Astma, allergier, kroniskt obstruktiv lungsjukdom (KOL) och sömnapné är sjukdomar med stor betydelse för folkhälsan. I vår forskning undersöker vi hur miljöfaktorer påverkar astma och allergier och hur olika överviktsrelaterade sjukdomar som astma, reflux, diabetes och sömnapné hänger ihop. Vi försöker också förbättra prognosen vid KOL genom att studera betydelsen av träning och nutrition.
Beskrivning av vår forskning
Astma är en av våra stora folksjukdomar. Med ökad kunskap om vilken betydelse påverkbara miljöfaktorer som rökning och hemmiljö har, kan det på sikt ge bättre möjligheter att förebygga och minska förekomsten av astma.
Vi ser också att andelen överviktiga ökar i vårt samhälle. Om vi kan få bättre kunskap om hur olika överviktsrelaterade sjukdomar som astma, reflux, sömnapné och diabetes hänger ihop blir det lättare att optimalt behandla personer med fler än en överviktsrelaterad sjukdom.
Allt fler människor i samhället drabbas också av kroniskt obstruktiv lungsjukdom (KOL). För närvarande finns det ingen farmakologisk behandling som avgörande förbättrar prognosen vid KOL. Om vi kan visa att fysisk träning i kombination med nutritionsbehandling och i vissa fall också med tillägg av oxygen ger bättre livskvalité och minskad risk för förnyade sjukhusinläggningar så har vi gjort stora vinster både ur patient- och samhällsperspektiv.
Gruppmedlemmar
Publikationer
Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
Ingår i Journal of Allergy and Clinical Immunology, s. 1310-1320, 2025
- DOI för Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
- Ladda ner fulltext (pdf) av Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
Ingår i The International Journal of Chronic Obstructive Pulmonary Disease, s. 273-286, 2025
Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
Ingår i Pulmonology, 2025
- DOI för Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
- Ladda ner fulltext (pdf) av Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
Ingår i Microorganisms, 2025
- DOI för SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
- Ladda ner fulltext (pdf) av SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
Ingår i Journal of Sleep Research, 2025
- DOI för Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea: A randomized controlled trial
- Ladda ner fulltext (pdf) av Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea: A randomized controlled trial
Ingår i BMC Cancer, 2025
- DOI för The hidden impact: social isolation and inflammation's role in pancreatic cancer risk among those with diabetes
- Ladda ner fulltext (pdf) av The hidden impact: social isolation and inflammation's role in pancreatic cancer risk among those with diabetes
Ingår i European Journal of Pediatrics, 2025
Ingår i Annals of the American Thoracic Society, s. 422-429, 2025
Ingår i Respiratory Medicine, 2025
- DOI för Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD: A cross-sectional study
- Ladda ner fulltext (pdf) av Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD: A cross-sectional study
Ingår i BMJ Open, 2025
- DOI för Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
- Ladda ner fulltext (pdf) av Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
Low-grade systemic inflammation and peripheral airway function
Ingår i ERJ Open Research, 2025
- DOI för Low-grade systemic inflammation and peripheral airway function
- Ladda ner fulltext (pdf) av Low-grade systemic inflammation and peripheral airway function
Ingår i International Journal of Cardiology, 2025
- DOI för Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
- Ladda ner fulltext (pdf) av Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
Ingår i BMJ Open Respiratory Research, 2025
- DOI för Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study
- Ladda ner fulltext (pdf) av Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study
Ingår i eClinicalMedicine, 2025
- DOI för Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study
- Ladda ner fulltext (pdf) av Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study
Ingår i ERJ open research, 2025
Ingår i BMC Medicine, 2025
- DOI för Using machine learning involving diagnoses and medications as a risk prediction tool for post-acute sequelae of COVID-19 (PASC) in primary care
- Ladda ner fulltext (pdf) av Using machine learning involving diagnoses and medications as a risk prediction tool for post-acute sequelae of COVID-19 (PASC) in primary care
Ingår i PULMONOLOGY, 2025
- DOI för Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: A cross-sectional analysis
- Ladda ner fulltext (pdf) av Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: A cross-sectional analysis
Ingår i PULMONOLOGY, 2025
- DOI för Association between lung function and dyspnoea and its variation in the multinational Burden of Obstructive Lung Disease (BOLD) study
- Ladda ner fulltext (pdf) av Association between lung function and dyspnoea and its variation in the multinational Burden of Obstructive Lung Disease (BOLD) study
Ingår i Sustainable cities and society, 2025
Ingår i Sustainable cities and society, 2025
Ingår i Journal of Hypertension, s. 864-870, 2025
Oxidative markers and SOD variant: predictors of autism severity and susceptibility
Ingår i Future Science OA, 2025
- DOI för Oxidative markers and SOD variant: predictors of autism severity and susceptibility
- Ladda ner fulltext (pdf) av Oxidative markers and SOD variant: predictors of autism severity and susceptibility
Associations of parental air pollution and greenness exposures with offspring asthma outcomes
Ingår i Environmental Research, 2025
- DOI för Associations of parental air pollution and greenness exposures with offspring asthma outcomes
- Ladda ner fulltext (pdf) av Associations of parental air pollution and greenness exposures with offspring asthma outcomes
Ingår i Frontiers in Cellular and Infection Microbiology, 2025
- DOI för Microbiome dysbiosis in SARS-CoV-2 infection: implication for pathophysiology and management strategies of COVID-19
- Ladda ner fulltext (pdf) av Microbiome dysbiosis in SARS-CoV-2 infection: implication for pathophysiology and management strategies of COVID-19
Ingår i Cardiovascular Diabetology, 2025
- DOI för Clonal hematopoiesis of indeterminate potential, health indicators, and risk of cardiovascular diseases among patients with diabetes: a prospective cohort study
- Ladda ner fulltext (pdf) av Clonal hematopoiesis of indeterminate potential, health indicators, and risk of cardiovascular diseases among patients with diabetes: a prospective cohort study
Ingår i The International Journal of Chronic Obstructive Pulmonary Disease, s. 303-312, 2025
What are the important risk factors for excessive daytime sleepiness in a population-based cohort?
Ingår i Journal of Sleep Research, 2025
Body mass index trajectories from birth to early adulthood and lung function development
Ingår i European Respiratory Journal, 2025
- DOI för Body mass index trajectories from birth to early adulthood and lung function development
- Ladda ner fulltext (pdf) av Body mass index trajectories from birth to early adulthood and lung function development
Ingår i Ageing Research Reviews, 2025
Ingår i BMC Public Health, 2025
- DOI för The association between cognitive impairment and oral health or oral hygiene behaviors among multiethnic older adults in Western China: a cross-sectional multicenter study
- Ladda ner fulltext (pdf) av The association between cognitive impairment and oral health or oral hygiene behaviors among multiethnic older adults in Western China: a cross-sectional multicenter study
Ingår i Clinical and Experimental Allergy, s. 91-93, 2025
- DOI för Eosinophil-Derived Neurotoxin Determinants and Reference Values in a Swedish Middle-Aged General Population
- Ladda ner fulltext (pdf) av Eosinophil-Derived Neurotoxin Determinants and Reference Values in a Swedish Middle-Aged General Population
Ingår i eClinicalMedicine, 2024
- DOI för Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study
- Ladda ner fulltext (pdf) av Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study
Pharmacological treatment of asthma in Sweden from 2005 to 2015
Ingår i Journal of Asthma, s. 313-321, 2024
- DOI för Pharmacological treatment of asthma in Sweden from 2005 to 2015
- Ladda ner fulltext (pdf) av Pharmacological treatment of asthma in Sweden from 2005 to 2015
Ingår i European Clinical Respiratory Journal, 2024
- DOI för Comorbid allergy and rhinitis and patient-related outcomes in asthma and COPD: a cross-sectional study
- Ladda ner fulltext (pdf) av Comorbid allergy and rhinitis and patient-related outcomes in asthma and COPD: a cross-sectional study
Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations
Ingår i Central European Journal of Immunology, s. 203-213, 2024
- DOI för Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations
- Ladda ner fulltext (pdf) av Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations
Ingår i The World Allergy Organization journal, s. 100973, 2024
Disease burden and unmet need for acute allergic reactions - A patient perspective
Ingår i World Allergy Organization Journal, 2024
- DOI för Disease burden and unmet need for acute allergic reactions - A patient perspective
- Ladda ner fulltext (pdf) av Disease burden and unmet need for acute allergic reactions - A patient perspective
Why harmonizing cohorts in sleep is a good idea and the labor of doing so?
Ingår i Sleep, 2024
- DOI för Why harmonizing cohorts in sleep is a good idea and the labor of doing so?
- Ladda ner fulltext (pdf) av Why harmonizing cohorts in sleep is a good idea and the labor of doing so?
Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki: Aðdragandi og áhættuþættir
Ingår i Laeknabladid, s. 20-27, 2024
- DOI för Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki: Aðdragandi og áhættuþættir
- Ladda ner fulltext (pdf) av Aflimanir ofan ökkla 2010-2019 vegna útæðasjúkdóms og/eða sykursýki: Aðdragandi og áhættuþættir
Nocturnal sleep phenotypes in idiopathic hypersomnia: A data-driven cluster analysis
Ingår i Sleep Medicine, s. 127-133, 2024
- DOI för Nocturnal sleep phenotypes in idiopathic hypersomnia: A data-driven cluster analysis
- Ladda ner fulltext (pdf) av Nocturnal sleep phenotypes in idiopathic hypersomnia: A data-driven cluster analysis
Ingår i Clinical Rehabilitation, s. 770-782, 2024
- DOI för Follow-up of individualised physical activity on prescription and individualised advice in patients with hip or knee osteoarthritis: A randomised controlled trial
- Ladda ner fulltext (pdf) av Follow-up of individualised physical activity on prescription and individualised advice in patients with hip or knee osteoarthritis: A randomised controlled trial
Ingår i Osteoarthritis and Cartilage, s. 937-942, 2024
Ingår i BMJ Open, 2024
- DOI för Association between physical activity over a 10-year period and current insomnia symptoms, sleep duration and daytime sleepiness: a European population-based study
- Ladda ner fulltext (pdf) av Association between physical activity over a 10-year period and current insomnia symptoms, sleep duration and daytime sleepiness: a European population-based study
Ingår i Annals of the American Thoracic Society, s. 1678-1687, 2024
- DOI för Chronic Airflow Limitation, Emphysema and Impaired Diffusing Capacity in Relation to Smoking Habits in a Swedish Middle-Aged Population
- Ladda ner fulltext (pdf) av Chronic Airflow Limitation, Emphysema and Impaired Diffusing Capacity in Relation to Smoking Habits in a Swedish Middle-Aged Population
Ingår i European Child and Adolescent Psychiatry, 2024
Ingår i BMJ Open Respiratory Research, 2024
- DOI för Internet-delivered cognitive-behaviour therapy for anxiety related to asthma: study protocol for a randomised controlled trial
- Ladda ner fulltext (pdf) av Internet-delivered cognitive-behaviour therapy for anxiety related to asthma: study protocol for a randomised controlled trial
Spirometric patterns in young and middle-aged adults: a 20-year European study
Ingår i Thorax, s. 153-162, 2024
- DOI för Spirometric patterns in young and middle-aged adults: a 20-year European study
- Ladda ner fulltext (pdf) av Spirometric patterns in young and middle-aged adults: a 20-year European study
Ingår i BMJ Open, 2024
- DOI för Obstructive sleep apnoea and lung function, and their association with nocturnal hypoxemia: results from the Swedish CArdioPulmonary bioimage Study (SCAPIS) - a cross-sectional study
- Ladda ner fulltext (pdf) av Obstructive sleep apnoea and lung function, and their association with nocturnal hypoxemia: results from the Swedish CArdioPulmonary bioimage Study (SCAPIS) - a cross-sectional study
Ingår i BMC Public Health, 2024
- DOI för Psycho-social dimensions of cardiovascular risk: exploring the impact of social isolation and loneliness in middle-aged and older adults
- Ladda ner fulltext (pdf) av Psycho-social dimensions of cardiovascular risk: exploring the impact of social isolation and loneliness in middle-aged and older adults
Ingår i Scandinavian Journal of Public Health, s. 978-987, 2024
- DOI för Preschool-level socio-economic deprivation in relation to emotional and behavioural problems among preschool children in Sweden
- Ladda ner fulltext (pdf) av Preschool-level socio-economic deprivation in relation to emotional and behavioural problems among preschool children in Sweden