Lung-, allergi- och sömnforskning

Astma, allergier, kroniskt obstruktiv lungsjukdom (KOL) och sömnapné är sjukdomar med stor betydelse för folkhälsan. I vår forskning undersöker vi hur miljöfaktorer påverkar astma och allergier och hur olika överviktsrelaterade sjukdomar som astma, reflux, diabetes och sömnapné hänger ihop. Vi försöker också förbättra prognosen vid KOL genom att studera betydelsen av träning och nutrition.
Beskrivning av vår forskning
Astma är en av våra stora folksjukdomar. Med ökad kunskap om vilken betydelse påverkbara miljöfaktorer som rökning och hemmiljö har, kan det på sikt ge bättre möjligheter att förebygga och minska förekomsten av astma.
Vi ser också att andelen överviktiga ökar i vårt samhälle. Om vi kan få bättre kunskap om hur olika överviktsrelaterade sjukdomar som astma, reflux, sömnapné och diabetes hänger ihop blir det lättare att optimalt behandla personer med fler än en överviktsrelaterad sjukdom.
Allt fler människor i samhället drabbas också av kroniskt obstruktiv lungsjukdom (KOL). För närvarande finns det ingen farmakologisk behandling som avgörande förbättrar prognosen vid KOL. Om vi kan visa att fysisk träning i kombination med nutritionsbehandling och i vissa fall också med tillägg av oxygen ger bättre livskvalité och minskad risk för förnyade sjukhusinläggningar så har vi gjort stora vinster både ur patient- och samhällsperspektiv.
Gruppmedlemmar
Publikationer
Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
Ingår i Journal of Allergy and Clinical Immunology, s. 1310-1320, 2025
- DOI för Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
- Ladda ner fulltext (pdf) av Targeting of the IL-5 pathway in severe asthma reduces mast cell progenitors
Ingår i The International Journal of Chronic Obstructive Pulmonary Disease, s. 273-286, 2025
- DOI för Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways
- Ladda ner fulltext (pdf) av Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Between the Lower and Upper Airways
Ingår i Journal of Steroid Biochemistry and Molecular Biology, 2025
- DOI för Vitamin D pathway as a multi-level predictor of COVID-19 severity and mortality: Integrating serum levels, FokI (rs2228570) VDR polymorphism, and lung tissue expression
- Ladda ner fulltext (pdf) av Vitamin D pathway as a multi-level predictor of COVID-19 severity and mortality: Integrating serum levels, FokI (rs2228570) VDR polymorphism, and lung tissue expression
Ingår i Molecular Cancer, 2025
- DOI för Advancing CAR-based cell therapies for solid tumours: challenges, therapeutic strategies, and perspectives
- Ladda ner fulltext (pdf) av Advancing CAR-based cell therapies for solid tumours: challenges, therapeutic strategies, and perspectives
Prevalence and Clinical Characteristics of Persistent Airflow Limitation in the NOVELTY Cohort.
Ingår i Annals of the American Thoracic Society, 2025
Ingår i Respiratory Medicine, 2025
- DOI för A lung function threshold for survival?: FEV1Q and mortality in patients with COPD and chronic respiratory failure
- Ladda ner fulltext (pdf) av A lung function threshold for survival?: FEV1Q and mortality in patients with COPD and chronic respiratory failure
Ingår i European Child and Adolescent Psychiatry, s. 1649-1659, 2025
- DOI för Adult mental health outcomes of adolescent depression and co-occurring alcohol use disorder: a longitudinal cohort study
- Ladda ner fulltext (pdf) av Adult mental health outcomes of adolescent depression and co-occurring alcohol use disorder: a longitudinal cohort study
Ingår i Translational Lung Cancer Research, s. 1972-1985, 2025
- DOI för Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study
- Ladda ner fulltext (pdf) av Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study
Ingår i European Respiratory Journal, 2025
Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
Ingår i Pulmonology, 2025
- DOI för Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
- Ladda ner fulltext (pdf) av Geographical variation in lung function: Results from the multicentric cross-sectional BOLD study
SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
Ingår i Microorganisms, 2025
- DOI för SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
- Ladda ner fulltext (pdf) av SARS-CoV-2 Vaccine-Induced Humoral Immunity in Immunocompetent European Adults: A Systematic Review
Ingår i Heart Rhythm, 2025
Ingår i Allergy. European Journal of Allergy and Clinical Immunology, 2025
Ingår i Clinical Science, s. 449-462, 2025
- DOI för Serum proteomics links the cardiorespiratory biomarkers CTRC, OSM, and MMP-10 to exacerbation severity and number in patients with COPD
- Ladda ner fulltext (pdf) av Serum proteomics links the cardiorespiratory biomarkers CTRC, OSM, and MMP-10 to exacerbation severity and number in patients with COPD
Ingår i Scientific Reports, 2025
- DOI för The association between systemic inflammation, lung function and respiratory symptoms in the BOLD study in Northern Europe
- Ladda ner fulltext (pdf) av The association between systemic inflammation, lung function and respiratory symptoms in the BOLD study in Northern Europe
The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study
Ingår i ERJ Open Research, 2025
- DOI för The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study
- Ladda ner fulltext (pdf) av The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study
Ingår i Sleep Medicine, 2025
- DOI för Self-reported witnessed episodes of apnea during sleep is associated with incident lung and breast cancer
- Ladda ner fulltext (pdf) av Self-reported witnessed episodes of apnea during sleep is associated with incident lung and breast cancer
Ingår i Journal of Geriatric Oncology, 2025
- DOI för Effect of preoperative exercise on postoperative complications after colorectal cancer surgery in older people with low physical fitness: The CANOPTIPHYS randomised controlled trial
- Ladda ner fulltext (pdf) av Effect of preoperative exercise on postoperative complications after colorectal cancer surgery in older people with low physical fitness: The CANOPTIPHYS randomised controlled trial
Ingår i Journal of Sleep Research, 2025
- DOI för Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea: A randomized controlled trial
- Ladda ner fulltext (pdf) av Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea: A randomized controlled trial
Ingår i BMC Cancer, 2025
- DOI för The hidden impact: social isolation and inflammation's role in pancreatic cancer risk among those with diabetes
- Ladda ner fulltext (pdf) av The hidden impact: social isolation and inflammation's role in pancreatic cancer risk among those with diabetes
Ingår i Environmental Health Insights, 2025
- DOI för Assessing the Knowledge and Experience of Healthcare Workers in Zoonoses and the One Health Approach: A Cross-Sectional Study in Ghana
- Ladda ner fulltext (pdf) av Assessing the Knowledge and Experience of Healthcare Workers in Zoonoses and the One Health Approach: A Cross-Sectional Study in Ghana
Ingår i European Journal of Pediatrics, 2025
Ingår i Annals of the American Thoracic Society, s. 422-429, 2025
Impact of interstitial lung disease on COVID-19 severity: A nationwide register study
Ingår i Respiratory Medicine, 2025
- DOI för Impact of interstitial lung disease on COVID-19 severity: A nationwide register study
- Ladda ner fulltext (pdf) av Impact of interstitial lung disease on COVID-19 severity: A nationwide register study
Ingår i Respiratory Medicine, 2025
- DOI för Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD: A cross-sectional study
- Ladda ner fulltext (pdf) av Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD: A cross-sectional study
Clinical phenotypes predict exacerbations of COPD: the TIE cohort study
Ingår i Respiratory Medicine, 2025
- DOI för Clinical phenotypes predict exacerbations of COPD: the TIE cohort study
- Ladda ner fulltext (pdf) av Clinical phenotypes predict exacerbations of COPD: the TIE cohort study
Ingår i Thorax, 2025
Postexercise Airway Responses by Spirometry and Oscillometry in Nonathlete and Athlete Adolescents
Ingår i Pediatric Pulmonology, 2025
Ingår i Pediatric Allergy and Immunology, 2025
- DOI för Systemic inflammatory biomarkers in relation to lung function and exercise-induced bronchoconstriction in adolescents
- Ladda ner fulltext (pdf) av Systemic inflammatory biomarkers in relation to lung function and exercise-induced bronchoconstriction in adolescents
Ingår i BMJ Open, 2025
- DOI för Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
- Ladda ner fulltext (pdf) av Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
Ingår i International Journal for Equity in Health, 2025
- DOI för No socioeconomic disparities in the availability of personal care assistance: a population-based cohort analysis of children living with respiratory support
- Ladda ner fulltext (pdf) av No socioeconomic disparities in the availability of personal care assistance: a population-based cohort analysis of children living with respiratory support
Peripheral airway function and disease burden in COPD
Ingår i ERJ Open Research, 2025
- DOI för Peripheral airway function and disease burden in COPD
- Ladda ner fulltext (pdf) av Peripheral airway function and disease burden in COPD
Ingår i Clinical and Experimental Allergy, 2025
Low-grade systemic inflammation and peripheral airway function
Ingår i ERJ Open Research, 2025
- DOI för Low-grade systemic inflammation and peripheral airway function
- Ladda ner fulltext (pdf) av Low-grade systemic inflammation and peripheral airway function
Ingår i International Journal of Cardiology, 2025
- DOI för Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
- Ladda ner fulltext (pdf) av Lipoproteins and lipoprotein lipid composition are associated with stages of dysglycemia and subclinical coronary atherosclerosis
Ingår i Journal of Hypertension, 2025
Ingår i Journal of Women's Health, s. 635-643, 2025
Type 2 inflammation and cardiometabolic disease in middle-aged adults
Ingår i ERJ Open Research, 2025
- DOI för Type 2 inflammation and cardiometabolic disease in middle-aged adults
- Ladda ner fulltext (pdf) av Type 2 inflammation and cardiometabolic disease in middle-aged adults
Ingår i Journal of Oral Rehabilitation, s. 367-374, 2025
- DOI för Sleep-Disordered Breathing and Dimensions of The Maxillary Dental Arch and Hard Palate in Children With Class II and Large Overjet-A Case-Control Study
- Ladda ner fulltext (pdf) av Sleep-Disordered Breathing and Dimensions of The Maxillary Dental Arch and Hard Palate in Children With Class II and Large Overjet-A Case-Control Study
Mortality in Severe Asthma - results from the NORDSTAR cohort.
Ingår i European Respiratory Journal, 2025
Evaluation of recently proposed thresholds to define spirometry bronchodilator response
Ingår i ERJ Open Research, 2025
Genetically Determined Inflammation-Related Proteins in Asthma and Type-2 Signatures
Ingår i Allergy. European Journal of Allergy and Clinical Immunology, s. 1702-1714, 2025
- DOI för Genetically Determined Inflammation-Related Proteins in Asthma and Type-2 Signatures
- Ladda ner fulltext (pdf) av Genetically Determined Inflammation-Related Proteins in Asthma and Type-2 Signatures
Occupational exposures to inorganic dust are associated with emphysema: the SCAPIS cohort.
Ingår i Occupational and Environmental Medicine, s. 437-443, 2025
Estimating the financial burden of asthma among young adults in Sweden
Ingår i European Clinical Respiratory Journal, 2025
- DOI för Estimating the financial burden of asthma among young adults in Sweden
- Ladda ner fulltext (pdf) av Estimating the financial burden of asthma among young adults in Sweden
Exhaled nitric oxide stability over two years in relation to COPD outcomes
Ingår i Journal of Breath Research, 2025
- DOI för Exhaled nitric oxide stability over two years in relation to COPD outcomes
- Ladda ner fulltext (pdf) av Exhaled nitric oxide stability over two years in relation to COPD outcomes
Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY
Ingår i Pragmatic and Observational Research, s. 135-145, 2025
- DOI för Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY
- Ladda ner fulltext (pdf) av Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY
How to reduce carbon footprints in asthma
Ingår i ERJ Open Research, 2025
Ingår i Läkartidningen, 2025
Switching to the Dry Powder Inhaler: Disease Control with a Lower Carbon Footprint.
Ingår i Pulmonary therapy, 2025
Ingår i BMJ Open Respiratory Research, 2025
- DOI för Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study
- Ladda ner fulltext (pdf) av Lung function and onset of cardiometabolic diseases in the longitudinal Burden of Obstructive Lung Disease study