Lung-, allergi- och sömnforskning

Astma, allergier, kroniskt obstruktiv lungsjukdom (KOL) och sömnapné är sjukdomar med stor betydelse för folkhälsan. I vår forskning undersöker vi hur miljöfaktorer påverkar astma och allergier och hur olika överviktsrelaterade sjukdomar som astma, reflux, diabetes och sömnapné hänger ihop. Vi försöker också förbättra prognosen vid KOL genom att studera betydelsen av träning och nutrition.
Beskrivning av vår forskning
Astma är en av våra stora folksjukdomar. Med ökad kunskap om vilken betydelse påverkbara miljöfaktorer som rökning och hemmiljö har, kan det på sikt ge bättre möjligheter att förebygga och minska förekomsten av astma.
Vi ser också att andelen överviktiga ökar i vårt samhälle. Om vi kan få bättre kunskap om hur olika överviktsrelaterade sjukdomar som astma, reflux, sömnapné och diabetes hänger ihop blir det lättare att optimalt behandla personer med fler än en överviktsrelaterad sjukdom.
Allt fler människor i samhället drabbas också av kroniskt obstruktiv lungsjukdom (KOL). För närvarande finns det ingen farmakologisk behandling som avgörande förbättrar prognosen vid KOL. Om vi kan visa att fysisk träning i kombination med nutritionsbehandling och i vissa fall också med tillägg av oxygen ger bättre livskvalité och minskad risk för förnyade sjukhusinläggningar så har vi gjort stora vinster både ur patient- och samhällsperspektiv.
Gruppmedlemmar
Publikationer
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Ingår i Journal of Sleep Research, 2026
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Indoor airborne bacterial communities and adult lung health: A cross-sectional study
Ingår i International journal of hygiene and environmental health, 2026
- DOI för Indoor airborne bacterial communities and adult lung health: A cross-sectional study
- Ladda ner fulltext (pdf) av Indoor airborne bacterial communities and adult lung health: A cross-sectional study
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Ingår i Veterinary Anaesthesia and Analgesia, 2026
- DOI för Nitric oxide and its role in the management of hypoxaemia in the anaesthetised horse: a narrative review
- Ladda ner fulltext (pdf) av Nitric oxide and its role in the management of hypoxaemia in the anaesthetised horse: a narrative review
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Prevalence and Clinical Characteristics of Persistent Airflow Limitation in the NOVELTY Cohort
Ingår i Annals of the American Thoracic Society, s. 188-199, 2026
- DOI för Prevalence and Clinical Characteristics of Persistent Airflow Limitation in the NOVELTY Cohort
- Ladda ner fulltext (pdf) av Prevalence and Clinical Characteristics of Persistent Airflow Limitation in the NOVELTY Cohort
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Ingår i American Journal of Respiratory and Critical Care Medicine, s. 1721-1729, 2026
- DOI för Discriminative performance and clinical utility of chronic obstructive pulmonary disease exacerbation categories for predicting future exacerbations
- Ladda ner fulltext (pdf) av Discriminative performance and clinical utility of chronic obstructive pulmonary disease exacerbation categories for predicting future exacerbations
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Ingår i Respiratory Medicine, 2026
- DOI för Lower lung function and respiratory symptoms are associated with reduced accelerometer-measured physical activity in middle-aged adults
- Ladda ner fulltext (pdf) av Lower lung function and respiratory symptoms are associated with reduced accelerometer-measured physical activity in middle-aged adults
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Ingår i International Journal of Epidemiology, 2026
- DOI för A cohort study of forced vital capacity, airway obstruction, and survival in the multinational Burden of Obstructive Lung Disease study
- Ladda ner fulltext (pdf) av A cohort study of forced vital capacity, airway obstruction, and survival in the multinational Burden of Obstructive Lung Disease study
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Development and Validation of the Risk of Exacerbation in Severe Asthma (RESA) Model
Ingår i Journal of Allergy and Clinical Immunology, s. 1589-1600, 2026
- DOI för Development and Validation of the Risk of Exacerbation in Severe Asthma (RESA) Model
- Ladda ner fulltext (pdf) av Development and Validation of the Risk of Exacerbation in Severe Asthma (RESA) Model
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Association between EAT-Lancet diet and the incident sleep apnea
Ingår i Sleep Medicine, 2026
- DOI för Association between EAT-Lancet diet and the incident sleep apnea
- Ladda ner fulltext (pdf) av Association between EAT-Lancet diet and the incident sleep apnea
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Sleep apnoea in patients undergoing colorectal cancer surgery: prospective cohort study
Ingår i BJS Open, 2026
- DOI för Sleep apnoea in patients undergoing colorectal cancer surgery: prospective cohort study
- Ladda ner fulltext (pdf) av Sleep apnoea in patients undergoing colorectal cancer surgery: prospective cohort study
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Ingår i Air quality, atmosphere and health, 2026
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Ingår i ERJ Open Research, 2026
- DOI för Bronchodilation response, respiratory burden and biomarkers: insights from impulse oscillometry and spirometry
- Ladda ner fulltext (pdf) av Bronchodilation response, respiratory burden and biomarkers: insights from impulse oscillometry and spirometry
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Ingår i Annals of the American Thoracic Society, s. 964-972, 2026
- DOI för Impact of central nervous system depressants on prognosis in obesity hypoventilation syndrome: the population-based DISCOVERY study
- Ladda ner fulltext (pdf) av Impact of central nervous system depressants on prognosis in obesity hypoventilation syndrome: the population-based DISCOVERY study
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Ingår i Thorax, s. 71-77, 2026
- DOI för Nocturnal gastro-oesophageal reflux and pulmonary abnormalities on chest CT in a general population: the Swedish CArdioPulmonary BioImage Study
- Ladda ner fulltext (pdf) av Nocturnal gastro-oesophageal reflux and pulmonary abnormalities on chest CT in a general population: the Swedish CArdioPulmonary BioImage Study
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Ingår i Clinical and Translational Allergy, 2026
- DOI för Serum and Nasal Lavage Fluid Eosinophil-Derived Neurotoxin Levels in Clinically Defined Asthma Phenotypes
- Ladda ner fulltext (pdf) av Serum and Nasal Lavage Fluid Eosinophil-Derived Neurotoxin Levels in Clinically Defined Asthma Phenotypes
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Ingår i The Lancet Respiratory Medicine, s. 659-672, 2026
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COPD and Dysphagia, a 2-Year Follow-up of the Prospective TIE-Cohort Study
Ingår i COPD, 2026
- DOI för COPD and Dysphagia, a 2-Year Follow-up of the Prospective TIE-Cohort Study
- Ladda ner fulltext (pdf) av COPD and Dysphagia, a 2-Year Follow-up of the Prospective TIE-Cohort Study
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Ingår i Journal of Internal Medicine, s. 467-480, 2026
- DOI för The Swedish CArdioPulmonary bioImage Study re-examination: Rationale, design, methods, and management of incidental findings
- Ladda ner fulltext (pdf) av The Swedish CArdioPulmonary bioImage Study re-examination: Rationale, design, methods, and management of incidental findings
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Mortality in Severe Asthma - results from the NORDSTAR cohort
Ingår i European Respiratory Journal, s. 2501289, 2026
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Ingår i Acta Oncologica, s. 370-374, 2026
- DOI för Psychological distress and tumor cell β2-adrenergic receptor levels in patients with surgically resected non-small cell lung cancer
- Ladda ner fulltext (pdf) av Psychological distress and tumor cell β2-adrenergic receptor levels in patients with surgically resected non-small cell lung cancer
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Ingår i BMC Endocrine Disorders, 2026
- DOI för Virtual care for young adults with type 1 diabetes: a 12-month follow-up of a wait-list randomized controlled trial
- Ladda ner fulltext (pdf) av Virtual care for young adults with type 1 diabetes: a 12-month follow-up of a wait-list randomized controlled trial
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Ingår i International Wound Journal, 2026
- DOI för Immunoinflammatory Profile of FGF-18, IL-35 and Glutamic Acid Decarboxylase in Patients With Diabetic Foot Ulcers
- Ladda ner fulltext (pdf) av Immunoinflammatory Profile of FGF-18, IL-35 and Glutamic Acid Decarboxylase in Patients With Diabetic Foot Ulcers
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Ingår i Genes, 2026
- DOI för Genetic Variations in TNFAIP3 and CTLA4 and Their Association with Circulating TNF-α and sCTLA4 Levels in Kurdish Patients with Rheumatoid Arthritis
- Ladda ner fulltext (pdf) av Genetic Variations in TNFAIP3 and CTLA4 and Their Association with Circulating TNF-α and sCTLA4 Levels in Kurdish Patients with Rheumatoid Arthritis
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Allergic sensitization in asthma and COPD in the NOVELTY study
Ingår i Respiratory Medicine, 2026
- DOI för Allergic sensitization in asthma and COPD in the NOVELTY study
- Ladda ner fulltext (pdf) av Allergic sensitization in asthma and COPD in the NOVELTY study
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Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics
Ingår i Clinical and Translational Allergy, 2026
- DOI för Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics
- Ladda ner fulltext (pdf) av Associations Between Different Eosinophil Activity Markers and Clinical Outcomes in Young Asthmatics
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Long-term lung function trajectories in Swedish COVID-19 ICU survivors: a two-year follow-up study
Ingår i European Clinical Respiratory Journal, 2026
- DOI för Long-term lung function trajectories in Swedish COVID-19 ICU survivors: a two-year follow-up study
- Ladda ner fulltext (pdf) av Long-term lung function trajectories in Swedish COVID-19 ICU survivors: a two-year follow-up study
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Ingår i PLOS ONE, 2026
- DOI för Associations of demographic, socioeconomic, lifestyle factors and comorbidity with accelerometer-measured physical activity in adults with cardiovascular diseases
- Ladda ner fulltext (pdf) av Associations of demographic, socioeconomic, lifestyle factors and comorbidity with accelerometer-measured physical activity in adults with cardiovascular diseases
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Treatable traits in asthma associated with hospitalisations
Ingår i ERJ Open Research, 2026
- DOI för Treatable traits in asthma associated with hospitalisations
- Ladda ner fulltext (pdf) av Treatable traits in asthma associated with hospitalisations
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Ingår i Respiratory Research, 2026
- DOI för Activation of regenerative pathways by exercise intervention in subjects with chronic obstructive pulmonary disease: a study protocol
- Ladda ner fulltext (pdf) av Activation of regenerative pathways by exercise intervention in subjects with chronic obstructive pulmonary disease: a study protocol
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Ingår i Journal of Sleep Research, 2026
- DOI för Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID-19: A Nationwide Cohort Study
- Ladda ner fulltext (pdf) av Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID-19: A Nationwide Cohort Study
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Ingår i International Journal of Epidemiology, 2026
- DOI för Paternal snus use in puberty and increased risk for asthma and allergies in offspring: a RHINE/RHINESSA two-generation study
- Ladda ner fulltext (pdf) av Paternal snus use in puberty and increased risk for asthma and allergies in offspring: a RHINE/RHINESSA two-generation study
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Ingår i BMJ Open Respiratory Research, 2026
- DOI för Developing low-carbon salbutamol MDI: assessment of relative bioavailability and pharmacodynamic relative potency of salbutamol MDI with propellant HFA-152a
- Ladda ner fulltext (pdf) av Developing low-carbon salbutamol MDI: assessment of relative bioavailability and pharmacodynamic relative potency of salbutamol MDI with propellant HFA-152a
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Ingår i Respiratory Research, 2026
- DOI för Genome-wide association study of image-based emphysema scoring in the Swedish CArdioPulmonary bioImage Study (SCAPIS) suggests two new risk loci in smokers
- Ladda ner fulltext (pdf) av Genome-wide association study of image-based emphysema scoring in the Swedish CArdioPulmonary bioImage Study (SCAPIS) suggests two new risk loci in smokers
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Ingår i BMJ Open Respiratory Research, 2026
- DOI för Association of respiratory health with occupational exposures in the Burden of Obstructive Lung Disease (BOLD) cohort: a multinational longitudinal study
- Ladda ner fulltext (pdf) av Association of respiratory health with occupational exposures in the Burden of Obstructive Lung Disease (BOLD) cohort: a multinational longitudinal study
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Ingår i Revista de investigación clínica, 2026
- DOI för Diagnostic and prognostic significance of IL-18 and its -607C/A polymorphism in COVID-19: Implications for CURB-65 severity scoring
- Ladda ner fulltext (pdf) av Diagnostic and prognostic significance of IL-18 and its -607C/A polymorphism in COVID-19: Implications for CURB-65 severity scoring
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Associations between respiratory health, reported traffic, and occupational-related exposure
Ingår i European Clinical Respiratory Journal, 2026
- DOI för Associations between respiratory health, reported traffic, and occupational-related exposure
- Ladda ner fulltext (pdf) av Associations between respiratory health, reported traffic, and occupational-related exposure
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Ingår i IMMUNO, 2026
- DOI för Harnessing Living Therapies: The Role of CAR-T Cells, Oncolytic Viruses, and Bacteria in Cancer Treatment
- Ladda ner fulltext (pdf) av Harnessing Living Therapies: The Role of CAR-T Cells, Oncolytic Viruses, and Bacteria in Cancer Treatment
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Ingår i FAMILY MEDICINE AND COMMUNITY HEALTH, 2026
- DOI för Risk factors for COPD exacerbations and mortality, and variation between primary care settings: the PRAXIS cohort study in Sweden
- Ladda ner fulltext (pdf) av Risk factors for COPD exacerbations and mortality, and variation between primary care settings: the PRAXIS cohort study in Sweden
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Ingår i Annals of the American Thoracic Society, s. 711-719, 2026
- DOI för Economic evaluation of long-term oxygen therapy: 24 hours versus 15 hours per day in severe hypoxemia-the REDOX trial
- Ladda ner fulltext (pdf) av Economic evaluation of long-term oxygen therapy: 24 hours versus 15 hours per day in severe hypoxemia-the REDOX trial
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Ingår i European Clinical Respiratory Journal, 2026
- DOI för Characteristics of severe asthma patients with biologic treatment in the Swedish National Airway Register
- Ladda ner fulltext (pdf) av Characteristics of severe asthma patients with biologic treatment in the Swedish National Airway Register
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Ingår i Trials, 2026
- DOI för Effect of HIgh-Flow Therapy in Long-Term Oxygen Therapy (HILOT): study protocol for a multicentre, registry-based, randomised clinical trial
- Ladda ner fulltext (pdf) av Effect of HIgh-Flow Therapy in Long-Term Oxygen Therapy (HILOT): study protocol for a multicentre, registry-based, randomised clinical trial
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Ingår i The International Journal of Chronic Obstructive Pulmonary Disease, s. 1-11, 2026
- DOI för Prognostic Value of Impaired Spirometry in Patients with Myocardial Infarction: A Longitudinal Study of Two European Cohorts
- Ladda ner fulltext (pdf) av Prognostic Value of Impaired Spirometry in Patients with Myocardial Infarction: A Longitudinal Study of Two European Cohorts
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Ingår i BMJ Open Respiratory Research, 2026
- DOI för Characterisation of chronic obstructive pulmonary disease (COPD) in never-smokers and ever-smokers from a population-based cohort
- Ladda ner fulltext (pdf) av Characterisation of chronic obstructive pulmonary disease (COPD) in never-smokers and ever-smokers from a population-based cohort
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Ingår i Radiology, 2026
- DOI för Pulmonary Nodule Prevalence at CT in Middle-Aged Participants from the Swedish CArdioPulmonary bioImage Study (SCAPIS)
- Ladda ner fulltext (pdf) av Pulmonary Nodule Prevalence at CT in Middle-Aged Participants from the Swedish CArdioPulmonary bioImage Study (SCAPIS)
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CPAP to Reduce the Risk of Cancer in OSA?-A Meta-Analysis of 3 RCTs
Ingår i Journal of Sleep Research, 2026
- DOI för CPAP to Reduce the Risk of Cancer in OSA?-A Meta-Analysis of 3 RCTs
- Ladda ner fulltext (pdf) av CPAP to Reduce the Risk of Cancer in OSA?-A Meta-Analysis of 3 RCTs
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Association between short-term exposure to air pollution and COVID-19: a case-crossover cohort study
Ingår i BMJ Open Respiratory Research, 2026
- DOI för Association between short-term exposure to air pollution and COVID-19: a case-crossover cohort study
- Ladda ner fulltext (pdf) av Association between short-term exposure to air pollution and COVID-19: a case-crossover cohort study
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Dampness and mould over 20 years and new onset of respiratory symptoms, asthma and rhinitis
Ingår i Journal of Hazardous Materials, 2026
- DOI för Dampness and mould over 20 years and new onset of respiratory symptoms, asthma and rhinitis
- Ladda ner fulltext (pdf) av Dampness and mould over 20 years and new onset of respiratory symptoms, asthma and rhinitis
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Health status and prognosis of COPD patients in relation to the FEV1/FVC ratio
Ingår i npj Primary Care Respiratory Medicine, 2026
- DOI för Health status and prognosis of COPD patients in relation to the FEV1/FVC ratio
- Ladda ner fulltext (pdf) av Health status and prognosis of COPD patients in relation to the FEV1/FVC ratio
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The Right Key, the Wrong Lock: TIGIT Checkpoint Blockade and the Road to Precision Immunotherapy
Ingår i Pharmaceutics, 2026
- DOI för The Right Key, the Wrong Lock: TIGIT Checkpoint Blockade and the Road to Precision Immunotherapy
- Ladda ner fulltext (pdf) av The Right Key, the Wrong Lock: TIGIT Checkpoint Blockade and the Road to Precision Immunotherapy
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A Multilevel Redox-Based Prognostic Model for Asthma Severity: From Genotype to Serum Biomarkers
Ingår i Biomedicines, 2026
- DOI för A Multilevel Redox-Based Prognostic Model for Asthma Severity: From Genotype to Serum Biomarkers
- Ladda ner fulltext (pdf) av A Multilevel Redox-Based Prognostic Model for Asthma Severity: From Genotype to Serum Biomarkers