In the research group for Preparative Medicinal Chemistry, we use synthetic chemistry as a driving force within medicinal chemistry, chemical biology, and molecular imaging with the aim of making an impact in drug development and healthcare innovation.

New Synthetic Methods

What: Develop new chemical reactions to prepare biologically relevant compounds

Why: Access to novel chemical structures is of fundamental importance in drug discovery

Tracers for PET Imaging

What: Novel PSMA/GRPR-targeting heterodimeric tracers for PET/SPECT imaging

Why: Better clinical tools for diagnosis and staging of prostate cancer

Psychotherapeutics

What: Design and synthesis of novel psychedelics and development of robust chemical methods for their preparation

Why: Novel treatment opportunities and fundamental mechanistic insights regarding mental illness

MALDI Mass Spectrometry Imaging (MSI) Reagents

What: Development of selective and highly sensitive reactive matrices for MALDI imaging

Why: These novel tools can be used to study biochemical changes during disease progression or treatment

IRAP inhibitors

What: Discovery of highly potent, selective and metabolically stable IRAP inhibitors

Why: Potential new treatment of neurodegenerative diseases