Conducting thesis projects in our field involves examining various aspects of drug usage, which may entail working with registry data as well as conducting independent data collection through, for example, surveys and interviews.

Examples of previous students' theses can be seen below.

Paracetamol and blood pressure control in 45211 patients treated for hypertension: A cross-sectional study from the Swedish primary care cardiovascular database (SPCCD).

This study aimed to investigate how regular paracetamol use could affect blood pressure (BP) control in patients on antihypertensive medication. Data for 42 511 patients attending primary care, with documented diagnosis of hypertension before 2007 and with ≥1 BP measurements recorded 2007–2008 were collected from the Swedish primary care cardiovascular database (SPCCD). This study found no relations between number of defined daily doses (DDD) and systolic and diastolic BP in paracetamol users. Paracetamol had no impact on attaining target BP in subgroup analyses on patients with diabetes mellitus, musculoskeletal diseases, with concomitant use of NSAID, or in relation to number of antihypertensive medications. Thus, the conclusion for this study was that a concomitant use of paracetamol does not impair the ability to reach target BP in hypertensive patients. No dose-response relationship was observed between dispensed prescriptions of paracetamol and BP.

Hanna Gottlieb, 2023

More-EUROPA (More Effectively Using Registries) – A cross-sectional survey assessing evidence needs

Regulators, HTA bodies and other stakeholders need to make many decisions during the medicinal product life cycle based on the evidence available to them. Stakeholders may expect and rely on different levels of evidence in specific scenarios, e.g., an initial approval decision of a new drug, for dosing recommendations in elderly or children, for a safety warning in patients with specific comorbidities or restricting reimbursement to a high-risk subpopulation with the largest unmet need. The level of evidence regulators and HTA require for registration and reimbursement is not fully established, especially when data from registries or observational studies are combined with traditional randomized controlled trials (RCTs). Therefore, this survey aims to assess the attitudes and experiences of different stakeholders toward different types of evidence when making decisions regarding the introduction of new medicines.

Tanja Dahlqvist, 2023

To which extent are future doctors and pharmacists in Sweden educated about the environmental impact of pharmaceuticals?

The release of pharmaceuticals into the environment can have serious consequences, such as the development of antibiotic resistance. Physicians and pharmacists can play key roles in addressing and preventing this. This master thesis examines the extent to which medical and pharmacy students in Swedish universities are educated about the environmental impact of pharmaceuticals.

Abdulla Jazzaa, 2023