Clinical and translational research in pediatric oncology
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By increasing our understanding of the clinical, biological, and psychosocial aspects of childhood neurological diseases and childhood cancer, the research group Pediatric oncological and neurological research works to improve the quality of life for children and adolescents with these diseases and their families.
The research performed within our research group spans from experimental studies using molecular biological techniques to behavioral research aiming to help children and their families better cope with demanding treatments. We collaborate nationally and internationally, both leading and participating in different research projects. We work especially tightly together with research group Pediatric oncological and neurological research with whom we have several collaborative projects. Read more about our main fields of research and projects and our research group.
Research funders
We would like to warmly thank our funders, collaborators, and all patients and their parents who enable our research work, including for example the Swedish Childhood Cancer Fund, Gillbergska Stiftelsen, Lions Cancerforskningsfond Mellansverige Uppsala-Örebro, Mary Bevés Stiftelse, and Region Uppsala.
Group members
Publications
Part of Radiography, 2026
- DOI for Children's experiences of coping with proton radiotherapy: A mixed-method study at a Swedish nationwide clinic
- Download full text (pdf) of Children's experiences of coping with proton radiotherapy: A mixed-method study at a Swedish nationwide clinic
Part of European Journal of Oncology Nursing, 2026
- DOI for "It is like he abandoned me in a war" - A qualitative study of relationship distress in parents of children diagnosed with cancer
- Download full text (pdf) of "It is like he abandoned me in a war" - A qualitative study of relationship distress in parents of children diagnosed with cancer
Part of Journal of Pediatric Nursing, p. 700-708, 2026
- DOI for The Swedish children and young people-patient reported experience measure questionnaire: A pilot study from paediatric inpatient and outpatient care
- Download full text (pdf) of The Swedish children and young people-patient reported experience measure questionnaire: A pilot study from paediatric inpatient and outpatient care
Part of Nature Communications, 2025
- DOI for A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas
- Download full text (pdf) of A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas
Part of Acta Paediatrica, 2025
- DOI for Challenges and Considerations in Manipulating Oral Dosage Forms in Paediatric Healthcare Settings: A Narrative Review
- Download full text (pdf) of Challenges and Considerations in Manipulating Oral Dosage Forms in Paediatric Healthcare Settings: A Narrative Review
Part of Human Reproduction, p. 1467-1475, 2025
- DOI for Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion
- Download full text (pdf) of Early transcriptional states of spermatogonia and marker expressions in the prepubertal human testis following chemotherapy-induced depletion
European standard clinical practice recommendations for paediatric high-grade gliomas
Part of EJC Paediatric Oncology, 2025
- DOI for European standard clinical practice recommendations for paediatric high-grade gliomas
- Download full text (pdf) of European standard clinical practice recommendations for paediatric high-grade gliomas
Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
Part of HemaSphere, 2025
- DOI for Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
- Download full text (pdf) of Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
Part of International Journal of Pharmaceutics, 2025
- DOI for Expert opinion on extrusion-based pharmaceutical 3D printing from the European Society of Hospital Pharmaceutical Technology (GERPAC)
- Download full text (pdf) of Expert opinion on extrusion-based pharmaceutical 3D printing from the European Society of Hospital Pharmaceutical Technology (GERPAC)
Part of Journal of Pharmaceutical Sciences, 2025
- DOI for Exploring Industry Stakeholder Perspectives on a Clinical Testbed for Evaluating the Handling of Protein Drugs in Hospitals
- Download full text (pdf) of Exploring Industry Stakeholder Perspectives on a Clinical Testbed for Evaluating the Handling of Protein Drugs in Hospitals
Healthcare professionals’ attitudes to animal assisted activity with dogs in paediatric care
Part of Complementary Therapies in Clinical Practice, p. 101952-101952, 2025
Part of Disability and Rehabilitation, 2025
- DOI for Long-term outcome and rehabilitation needs after acquired brain injury in children and adolescents: an evaluation in a Swedish cohort
- Download full text (pdf) of Long-term outcome and rehabilitation needs after acquired brain injury in children and adolescents: an evaluation in a Swedish cohort
Part of Critical reviews in oncology/hematology, 2025
- DOI for Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review
- Download full text (pdf) of Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review
Part of Journal of Pharmaceutical Sciences, p. 1142-1151, 2025
- DOI for Pneumatic tube transport of trastuzumab in IV bags -effect of headspace and surfactant on subvisible particle formation
- Download full text (pdf) of Pneumatic tube transport of trastuzumab in IV bags -effect of headspace and surfactant on subvisible particle formation
Part of Drug Safety, p. 375-388, 2025
- DOI for Prenatal and Early Childhood Exposure to Proton Pump Inhibitors and Antibiotics and the Risk of Childhood Cancer: A Nationwide Population-Based Cohort Study
- Download full text (pdf) of Prenatal and Early Childhood Exposure to Proton Pump Inhibitors and Antibiotics and the Risk of Childhood Cancer: A Nationwide Population-Based Cohort Study
Part of Cancer Medicine, 2025
- DOI for Prognostic factors in patients with localized and metastatic alveolar rhabdomyosarcoma: A report from two studies and two registries of the Cooperative Weichteilsarkom Studiengruppe CWS
- Download full text (pdf) of Prognostic factors in patients with localized and metastatic alveolar rhabdomyosarcoma: A report from two studies and two registries of the Cooperative Weichteilsarkom Studiengruppe CWS
School Nurses’ Experiences of the School-Based HPV Vaccination Program – A Decade Later
Part of Journal of School Nursing, 2025
School Nurses’ Experiences of the School-Based HPV Vaccination Program – A Decade Later
Part of Journal of School Nursing, 2025
Part of European Journal of Oncology Nursing, 2025
Part of European Journal of Oncology Nursing, p. 102780-102780, 2025
Part of European Journal of Oncology Nursing, 2025
- DOI for Siblings' lived experiences of transitions between hospital and home in paediatric oncology: A qualitative study
- Download full text (pdf) of Siblings' lived experiences of transitions between hospital and home in paediatric oncology: A qualitative study
Part of European Journal of Oncology Nursing, p. 102853-102853, 2025
Part of BMC Public Health, 2025
- DOI for Young people's proposals for tackling everyday challenges in order to improve mental health: a qualitative comparison study based on different socioeconomic neighborhoods
- Download full text (pdf) of Young people's proposals for tackling everyday challenges in order to improve mental health: a qualitative comparison study based on different socioeconomic neighborhoods
Part of BMC Public Health, 2025
Part of Journal of Adolescent Research, p. 3-29, 2024
- DOI for A Clash of Sexual Gender Norms and Understandings: A Qualitative Study of Homosexual, Bisexual, Transgender, and Queer Adolescents’ Experiences in Junior High Schools
- Download full text (pdf) of A Clash of Sexual Gender Norms and Understandings: A Qualitative Study of Homosexual, Bisexual, Transgender, and Queer Adolescents’ Experiences in Junior High Schools
Part of JMIR Serious Games, 2024
- DOI for Acceptability of a Serious Game About Proton Radiotherapy Designed for Children Aged 5 to 14 Years and Its Potential Impact on Perceived Anxiety: Feasibility and Randomized Controlled Pilot Trial
- Download full text (pdf) of Acceptability of a Serious Game About Proton Radiotherapy Designed for Children Aged 5 to 14 Years and Its Potential Impact on Perceived Anxiety: Feasibility and Randomized Controlled Pilot Trial
Part of Pharmaceutics, 2024
- DOI for Automated Non-Sterile Pharmacy Compounding: A Multi-Site Study in European Hospital and Community Pharmacies with Pediatric Immediate Release Propranolol Hydrochloride Tablets
- Download full text (pdf) of Automated Non-Sterile Pharmacy Compounding: A Multi-Site Study in European Hospital and Community Pharmacies with Pediatric Immediate Release Propranolol Hydrochloride Tablets
Part of BMJ Open, 2024
- DOI for Children's participation in the development, use and evaluation of support interventions for children of a parent diagnosed with cancer: a scoping review protocol
- Download full text (pdf) of Children's participation in the development, use and evaluation of support interventions for children of a parent diagnosed with cancer: a scoping review protocol
Part of BMJ Paediatrics Open, 2024
- DOI for Comparative efficacy of pharmacological and non-pharmacological interventions for mitigating pain and anxiety associated with venipuncture: a randomised controlled trial
- Download full text (pdf) of Comparative efficacy of pharmacological and non-pharmacological interventions for mitigating pain and anxiety associated with venipuncture: a randomised controlled trial
Part of European Journal of Integrative Medicine, 2024
- DOI for Comparing the use of colored Trace Images in Kids' Books with passive distractions to decrease pain and fear during cannulation in children: A randomized clinical trial
- Download full text (pdf) of Comparing the use of colored Trace Images in Kids' Books with passive distractions to decrease pain and fear during cannulation in children: A randomized clinical trial
Part of European Journal of Pediatrics, p. 113-122, 2024
- DOI for Comparison of trace image colors for kids-book with two active distractions in reducing pain and fear of children during the venipuncture procedure
- Download full text (pdf) of Comparison of trace image colors for kids-book with two active distractions in reducing pain and fear of children during the venipuncture procedure
Conceptualizing adolescents' everyday stressors to underscore areas for support
Part of Frontiers in Education, 2024
- DOI for Conceptualizing adolescents' everyday stressors to underscore areas for support
- Download full text (pdf) of Conceptualizing adolescents' everyday stressors to underscore areas for support
Part of JBMR Plus, 2024
- DOI for Demographic and disease-related factors impact bone turnover and vitamin D in children with hemato-oncological diseases
- Download full text (pdf) of Demographic and disease-related factors impact bone turnover and vitamin D in children with hemato-oncological diseases
Part of The Lancet Regional Health, 2024
- DOI for Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors: a nationwide, prospective Swedish study
- Download full text (pdf) of Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors: a nationwide, prospective Swedish study
Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies
Part of Cancers, 2024
- DOI for Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies
- Download full text (pdf) of Drivers Underlying Metastasis and Relapse in Medulloblastoma and Targeting Strategies
Part of Acta Psychologica, 2024
- DOI for Exploring the relationship between depressive symptoms, problematic smartphone use, and cumulative risk factors in nursing students: A cross sectional study
- Download full text (pdf) of Exploring the relationship between depressive symptoms, problematic smartphone use, and cumulative risk factors in nursing students: A cross sectional study
Part of Children & society, p. 228-244, 2024
- DOI for Exploring young people's experiences of race, gender and socioeconomic status in relation to everyday challenges: A focus group study
- Download full text (pdf) of Exploring young people's experiences of race, gender and socioeconomic status in relation to everyday challenges: A focus group study
Part of International Journal for Quality in Health Care, 2024
- DOI for How are we handling protein drugs in hospitals?: A Human Factors and Systems Engineering Approach to compare two hospitals and suggest a best practice
- Download full text (pdf) of How are we handling protein drugs in hospitals?: A Human Factors and Systems Engineering Approach to compare two hospitals and suggest a best practice
Part of Journal of Pharmaceutical Sciences, p. 2055-2064, 2024
- DOI for Impact of Post Manufacturing Handling of Protein-Based Biologic Drugs on Product Quality and User Centricity
- Download full text (pdf) of Impact of Post Manufacturing Handling of Protein-Based Biologic Drugs on Product Quality and User Centricity
Part of Frontiers in Oncology, 2024
- DOI for Implementing data on targeted therapy from the INFORM registry platform for children with relapsed cancer in Sweden
- Download full text (pdf) of Implementing data on targeted therapy from the INFORM registry platform for children with relapsed cancer in Sweden
Part of Nature Communications, 2024
- DOI for In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity
- Download full text (pdf) of In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity
Part of Cancer Research Communications, p. 2553-2564, 2024
- DOI for Long-Lasting Response to Lorlatinib in Patients with ALK-Driven Relapsed or Refractory Neuroblastoma Monitored with Circulating Tumor DNA Analysis
- Download full text (pdf) of Long-Lasting Response to Lorlatinib in Patients with ALK-Driven Relapsed or Refractory Neuroblastoma Monitored with Circulating Tumor DNA Analysis
Part of Genes, Chromosomes and Cancer, 2024
- DOI for Loss of Chromosome Y in Neuroblastoma Is Associated With High-Risk Disease, 11q-Deletion, and Telomere Maintenance
- Download full text (pdf) of Loss of Chromosome Y in Neuroblastoma Is Associated With High-Risk Disease, 11q-Deletion, and Telomere Maintenance
Part of eClinicalMedicine, 2024
- DOI for Maintenance therapy with trofosfamide, idarubicin and etoposide in patients with rhabdomyosarcoma and other high-risk soft tissue sarcomas (CWS-2007-HR): a multicentre, open-label, randomised controlled phase 3 trial
- Download full text (pdf) of Maintenance therapy with trofosfamide, idarubicin and etoposide in patients with rhabdomyosarcoma and other high-risk soft tissue sarcomas (CWS-2007-HR): a multicentre, open-label, randomised controlled phase 3 trial
Nursing interventions for pediatric patients with cancer and their families: A scoping review
Part of International Journal of Nursing Studies, 2024
- DOI for Nursing interventions for pediatric patients with cancer and their families: A scoping review
- Download full text (pdf) of Nursing interventions for pediatric patients with cancer and their families: A scoping review
Part of International Journal of Pharmaceutics, 2024
- DOI for Off-the-shelf medication transformed: Custom-dosed metoprolol tartrate tablets via semisolid extrusion additive manufacturing and the perception of this technique in a hospital context
- Download full text (pdf) of Off-the-shelf medication transformed: Custom-dosed metoprolol tartrate tablets via semisolid extrusion additive manufacturing and the perception of this technique in a hospital context
Part of American Journal of Case Reports, 2024
- DOI for Pediatric Soft Tissue Sarcoma in Limb-Girdle Muscular Dystrophy: Molecular Findings and Clinical Implications
- Download full text (pdf) of Pediatric Soft Tissue Sarcoma in Limb-Girdle Muscular Dystrophy: Molecular Findings and Clinical Implications
Part of Pediatric Blood & Cancer, 2024
- DOI for Radiotherapy and long-term sequelae in pediatric patients with parameningeal rhabdomyosarcoma: Results of two Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry
- Download full text (pdf) of Radiotherapy and long-term sequelae in pediatric patients with parameningeal rhabdomyosarcoma: Results of two Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry
Part of Clinical Nutrition, p. 1696-1705, 2024
- DOI for Safe and efficient practice of parenteral nutrition in neonates and children aged 0-18 years - The role of licensed multi-chamber bags
- Download full text (pdf) of Safe and efficient practice of parenteral nutrition in neonates and children aged 0-18 years - The role of licensed multi-chamber bags
School children's perceptions about being offered the HPV vaccination: A focus group study
Part of Acta Paediatrica, p. 1672-1678, 2024
- DOI for School children's perceptions about being offered the HPV vaccination: A focus group study
- Download full text (pdf) of School children's perceptions about being offered the HPV vaccination: A focus group study
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