Lena Kjellén

Loss of NDST1 N-sulfotransferase activity is associated with autosomal recessive intellectual disability

Khosrowabadi, Elham; Mignon-Ravix, Cécile; Riccardi, Florence; Cacciagli, Pierre et al.

Ingår i Human Molecular Genetics, s. 520-529, 2024

• DOI för Loss of NDST1 N-sulfotransferase activity is associated with autosomal recessive intellectual disability

Landscape of mast cell populations across organs in mice and humans

Tauber, Marie; Basso, Lilian; Martin, Jeremy; Bostan, Luciana et al.

Ingår i Journal of Experimental Medicine, 2023

• DOI för Landscape of mast cell populations across organs in mice and humans

Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics

Noborn, Fredrik; Nilsson, Jonas; Sihlbom, Carina; Nikpour, Mahnaz et al.

Ingår i Molecular & Cellular Proteomics, 2023

• DOI för Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics
• Ladda ner fulltext (pdf) av Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics

Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

Habicher, Judith; Varshney, Gaurav K.; Waldmann, Laura; Snitting, Daniel et al.

Ingår i PLOS Genetics, 2022

• DOI för Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development
• Ladda ner fulltext (pdf) av Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation

Missaghian, Parisa; Dierker, Tabea; Khosrowabadi, Elham; Axling, Fredrik et al.

Ingår i Glycobiology, s. 518-528, 2022

• DOI för A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
• Ladda ner fulltext (pdf) av A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation

Loss of NDST1 N-sulfotransferase activity is associated with autosomal recessive intellectual disability

Khosrowabadi, Elham; Mignon-Ravix, Cécile; Riccardi, Florence; Cacciagli, Pierre et al.

Ingår i Human Molecular Genetics, s. 520-529, 2024

• DOI för Loss of NDST1 N-sulfotransferase activity is associated with autosomal recessive intellectual disability

Landscape of mast cell populations across organs in mice and humans

Tauber, Marie; Basso, Lilian; Martin, Jeremy; Bostan, Luciana et al.

Ingår i Journal of Experimental Medicine, 2023

• DOI för Landscape of mast cell populations across organs in mice and humans

Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics

Noborn, Fredrik; Nilsson, Jonas; Sihlbom, Carina; Nikpour, Mahnaz et al.

Ingår i Molecular & Cellular Proteomics, 2023

• DOI för Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics
• Ladda ner fulltext (pdf) av Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics

Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

Habicher, Judith; Varshney, Gaurav K.; Waldmann, Laura; Snitting, Daniel et al.

Ingår i PLOS Genetics, 2022

• DOI för Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development
• Ladda ner fulltext (pdf) av Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation

Missaghian, Parisa; Dierker, Tabea; Khosrowabadi, Elham; Axling, Fredrik et al.

Ingår i Glycobiology, s. 518-528, 2022

• DOI för A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
• Ladda ner fulltext (pdf) av A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation

Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate

Bachvarova, Velina; Dierker, Tabea; Esko, Jeffrey; Hoffmann, Daniel et al.

Ingår i Matrix Biology, s. 43-59, 2020

• DOI för Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate
• Ladda ner fulltext (pdf) av Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate

Establishment and characterization of Drosophila cell lines mutant for heparan sulfate modifying enzymes

Nakato, Eriko; Liu, Xin; Eriksson, Inger; Yamamoto, Maki et al.

Ingår i Glycobiology, s. 479-489, 2019

• DOI för Establishment and characterization of Drosophila cell lines mutant for heparan sulfate modifying enzymes

Expanding the chondroitin glycoproteome of Caenorhabditis elegans

Noborn, Fredrik; Toledo, Alejandro Gomez; Nasir, Waqas; Nilsson, Jonas et al.

Ingår i Journal of Biological Chemistry, s. 379-389, 2018

• DOI för Expanding the chondroitin glycoproteome of Caenorhabditis elegans

Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules

Frisk, Jun Mei Hu; Kjellén, Lena; Melo, Fabio R.; Öhrvik, Helena et al.

Ingår i Frontiers in Immunology, 2018

• DOI för Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules
• Ladda ner fulltext (pdf) av Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules

Specificity of glycosaminoglycan-protein interactions

Kjellén, Lena; Lindahl, Ulf

Ingår i Current opinion in structural biology, s. 101-108, 2018

• DOI för Specificity of glycosaminoglycan-protein interactions

Separation and Purification of Glycosaminoglycans (GAGs) from Caenorhabditis elegans

Dierker, Tabea; Kjellén, Lena

Ingår i Bio-protocol, 2017

• DOI för Separation and Purification of Glycosaminoglycans (GAGs) from Caenorhabditis elegans

Copper Regulates Maturation and Expression of an MITF: Tryptase Axis in Mast Cells

Hu Frisk, Jun Mei; Kjellén, Lena; Kaler, Stephen G; Pejler, Gunnar et al.

Ingår i Journal of Immunology, s. 4132-4141, 2017

• DOI för Copper Regulates Maturation and Expression of an MITF: Tryptase Axis in Mast Cells

Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Xiong, Anqi; Kundu, Soumi; Forsberg, Maud; Xiong, Yuyuan et al.

Ingår i Matrix Biology, s. 92-104, 2017

• DOI för Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Identification of novel chondroitin sulfate sulfotransferases and proteoglycan core proteins in the nematode C. elegans

Dierker, Tabea; Noborn, F.; Hinas, Andrea; Kjellén, Lena

Ingår i International journal of experimental pathology (Print), 2017

Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice

Roy, Ananya; Sawesi, Osama; Pettersson, Ulrika A.; Dagälv, Anders et al.

Ingår i BMC Immunology, 2016

• DOI för Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice
• Ladda ner fulltext (pdf) av Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice

NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length

Deligny, Audrey; Dierker, Tabea; Dagälv, Anders; Lundequist, Anders et al.

Ingår i Journal of Biological Chemistry, s. 18600-18607, 2016

• DOI för NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length

Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans

Dierker, Tabea; Shao, Chun; Haitina, Tatjana; Zaia, Joseph et al.

Ingår i Scientific Reports, 2016

• DOI för Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans
• Ladda ner fulltext (pdf) av Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans

Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones

Dierker, Tabea; Bachvarova, Velina; Krause, Yvonne; Li, Jin-Ping et al.

Ingår i Matrix Biology, s. 82-92, 2016

• DOI för Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones

Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis

Menard, Julien A.; Christianson, Helena C.; Kucharzewska, Paulina; Bourseau-Guilmain, Erika et al.

Ingår i Cancer Research, s. 4828-4840, 2016

• DOI för Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis

Versican accumulates in vascular lesions in pulmonary arterial hypertension

Chang, Ya-Ting; Chan, Christina K.; Eriksson, Inger; Johnson, Pamela Y. et al.

Ingår i PULMONARY CIRCULATION, s. 347-359, 2016

• DOI för Versican accumulates in vascular lesions in pulmonary arterial hypertension

Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans

Öhrvik, Helena; Logeman, Brandon; Noguchi, Glyn; Eriksson, Inger et al.

Ingår i Journal of Immunology, s. 3654-3664, 2015

• DOI för Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans
• Ladda ner fulltext (pdf) av Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans

Identification of Chondroitin Sulfate Linkage Region Glycopeptides Reveals Prohormones as a Novel Class of Proteoglycans

Noborn, Fredrik; Toledo, Alejandro Gomez; Sihlbom, Carina; Lengqvist, Johan et al.

Ingår i Molecular & Cellular Proteomics, s. 41-49, 2015

• DOI för Identification of Chondroitin Sulfate Linkage Region Glycopeptides Reveals Prohormones as a Novel Class of Proteoglycans

The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation

Filipek-Gorniok, Beata; Carlsson, Pernilla; Haitina, Tatjana; Habicher, Judith et al.

Ingår i PLOS ONE, 2015

• DOI för The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation
• Ladda ner fulltext (pdf) av The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation

Profiling sulfation/epimerization pattern of full-length heparan sulfate by NMR following cell culture C-13-glucose metabolic labeling

Pegeot, Mathieu; Sadir, Rabia; Eriksson, Inger; Kjellén, Lena et al.

Ingår i Glycobiology, s. 151-156, 2015

• DOI för Profiling sulfation/epimerization pattern of full-length heparan sulfate by NMR following cell culture C-13-glucose metabolic labeling

Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Roy, Ananya; Ganesh, Goutham; Sippola, Helena; Bolin, Sara et al.

Ingår i Journal of Biological Chemistry, s. 237-250, 2014

• DOI för Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Distorted Secretory Granule Composition in Mast Cells with Multiple Protease Deficiency

Grujic, Mirjana; Calounova, Gabriela; Eriksson, Inger; Feyerabend, Thorsten et al.

Ingår i Journal of Immunology, s. 3931-3938, 2013

• DOI för Distorted Secretory Granule Composition in Mast Cells with Multiple Protease Deficiency

Dimerized Glycosaminoglycan Chains Increase FGF Signaling during Zebrafish Development

Nguyen, Thao K. N.; Tran, Vy M.; Sorna, Venkataswamy; Eriksson, Inger et al.

Ingår i ACS Chemical Biology, s. 939-948, 2013

• DOI för Dimerized Glycosaminoglycan Chains Increase FGF Signaling during Zebrafish Development

Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development

Filipek-Gorniok, Beata; Holmborn, Katarina; Haitina, Tatjana; Habicher, Judith et al.

Ingår i Developmental Dynamics, s. 964-975, 2013

• DOI för Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development

MicroRNA-24 Suppression of N-Deacetylase/N-Sulfotransferase-1 (NDST1) Reduces Endothelial Cell Responsiveness to Vascular Endothelial Growth Factor A (VEGFA)

Kasza, Zsolt; Fredlund Fuchs, Peder; Tamm, Christoffer; Eriksson, Anna S. et al.

Ingår i Journal of Biological Chemistry, s. 25956-25963, 2013

• DOI för MicroRNA-24 Suppression of N-Deacetylase/N-Sulfotransferase-1 (NDST1) Reduces Endothelial Cell Responsiveness to Vascular Endothelial Growth Factor A (VEGFA)

Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells

Forsberg, Maud; Holmborn, Katarina; Kundu, Soumi; Dagälv, Anders et al.

Ingår i Journal of Biological Chemistry, s. 10853-10862, 2012

• DOI för Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells

Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Le Jan, Sébastien; Hayashi, Makoto; Kasza, Zsolt; Eriksson, Inger et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1255-1263, 2012

• DOI för Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Heparin biosynthesis

Carlsson, Pernilla; Kjellén, Lena

Ingår i Handbook of experimental pharmacology, s. 23-41, 2012

• DOI för Heparin biosynthesis

Heparan Sulfate Biosynthesis: Regulation and Variability

Kreuger, Johan; Kjellén, Lena

Ingår i Journal of Histochemistry and Cytochemistry, s. 898-907, 2012

• DOI för Heparan Sulfate Biosynthesis: Regulation and Variability

Heparan Sulfate Biosynthesis Enzymes in Embryonic Stem Cell Biology

Tamm, Christoffer; Kjellén, Lena; Li, Jin-Ping

Ingår i Journal of Histochemistry and Cytochemistry, s. 943-949, 2012

• DOI för Heparan Sulfate Biosynthesis Enzymes in Embryonic Stem Cell Biology

Glycobiology: Enzyme deficiencies deciphered

Kjellén, Lena

Ingår i Nature chemical biology, s. 137-138, 2012

• DOI för Glycobiology: Enzyme deficiencies deciphered

Mucopolysaccharidosis Type I, Unique Structure of Accumulated Heparan Sulfate and Increased N-Sulfotransferase Activity in Mice Lacking alpha-L-iduronidase

Holley, Rebecca J.; Deligny, Audrey; Wei, Wei; Watson, H. Angharad et al.

Ingår i Journal of Biological Chemistry, s. 37515-37524, 2011

• DOI för Mucopolysaccharidosis Type I, Unique Structure of Accumulated Heparan Sulfate and Increased N-Sulfotransferase Activity in Mice Lacking alpha-L-iduronidase

Lowered Expression of Heparan Sulfate/Heparin Biosynthesis Enzyme N-Deacetylase/N-Sulfotransferase 1 Results in Increased Sulfation of Mast Cell Heparin

Dagälv, Anders; Holmborn, Katarina; Kjellén, Lena; Åbrink, Magnus

Ingår i Journal of Biological Chemistry, s. 44433-44440, 2011

• DOI för Lowered Expression of Heparan Sulfate/Heparin Biosynthesis Enzyme N-Deacetylase/N-Sulfotransferase 1 Results in Increased Sulfation of Mast Cell Heparin

Mesomelia-Synostoses Syndrome Results from Deletion of SULF1 and SLCO5A1 Genes at 8q13

Isidor, Bertrand; Pichon, Olivier; Redon, Richard; Day-Salvatore, Debra et al.

Ingår i American Journal of Human Genetics, s. 95-100, 2010

• DOI för Mesomelia-Synostoses Syndrome Results from Deletion of SULF1 and SLCO5A1 Genes at 8q13

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

Kawamura, Harukiyo; Li, Xiujuan; Goishi, Katsutoshi; van Meeteren, Laurens A et al.

Ingår i Blood, s. 3638-49, 2008

• DOI för Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation

Presto, Jenny; Thuveson, Maria; Carlsson, Pernilla; Busse, Marta et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 4751-4756, 2008

• DOI för Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation

Heparin/heparan sulfate biosynthesis: Processive formation of N-sulfated domains

Carlsson, Pernilla; Presto, Jenny; Spillmann, Dorothe; Lindahl, Ulf et al.

Ingår i Journal of Biological Chemistry, s. 20008-20014, 2008

• DOI för Heparin/heparan sulfate biosynthesis: Processive formation of N-sulfated domains

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Abramsson, Alexandra; Kurup, Sindhulakshmi; Yamada, Shuhei; Lindblom, Per et al.

Ingår i Genes & Development, s. 316-331, 2007

• DOI för Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation

Busse, Marta; Feta, Almir; Presto, Jenny; Wilén, Maria et al.

Ingår i Journal of Biological Chemistry, s. 32802-32810, 2007

• DOI för Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation

No change in glomerular heparan sulfate structure in early human and experimental diabetic nephropathy

van den Born, Jacob; Pisa, Brenda; Bakker, Marinka A. H.; Celie, Johanna W. A. M. et al.

Ingår i Journal of Biological Chemistry, s. 29606-29613, 2006

• DOI för No change in glomerular heparan sulfate structure in early human and experimental diabetic nephropathy

Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation

Ledin, Johan; Ringvall, Maria; Thuveson, Maria; Eriksson, Inger et al.

Ingår i Journal of Biological Chemistry, s. 35727-35734, 2006

• DOI för Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis

Jakobsson, Lars; Kreuger, Johan; Holmborn, Katarina; Lundin, Lars et al.

Ingår i Developmental Cell, s. 625-634, 2006

Heparan sulphate requirement in platelet-derived growth factor B-mediated pericyte recruitment

Kurup, S; Abramsson, A; Li, Jin-Ping; Lindahl, Ulf et al.

Ingår i Biochemical Society Transactions, s. 454-455, 2006

Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups

Holmborn, Katarina; Ledin, Johan; Smeds, Emanuel; Eriksson, Inger et al.

Ingår i The Journal of Biological Chemistry, s. 42355-58, 2004

Neurogenic inflammation in mice deficient in heparin-synthesizing enzyme.

Karlsen, Tine V; Iversen, Vegard V; Forsberg, Erik; Kjellén, Lena et al.

Ingår i Am J Physiol Heart Circ Physiol, 2004

Heparan sulfate structure in mice with genetically modified heparan sulfate production.

Ledin, Johan; Staatz, William; Li, Jin-Ping; Götte, Martin et al.

Ingår i J Biol Chem, s. 42732-41, 2004

Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups.

Holmborn, Katarina; Ledin, Johan; Smeds, Emanuel; Eriksson, Inger et al.

Ingår i J Biol Chem, s. 42355-8, 2004

Distinct effects on heparan sulfate structure by different active site mutations in NDST-1

Bengtsson, Jenny; Eriksson, Inger; Kjellén, Lena

Ingår i Biochemistry, s. 2110-2115, 2003

Antibody-based assay for N-deacetylase activity of heparan sulfate/heparinN-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1and -2.

Van Den Born, J; Pikas, DS; Pisa, BJ; Eriksson, I et al.

Ingår i Glycobiology, s. 1, 2003

Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes.

Grobe, K; Ledin, Johan; Ringvall, Maria; Holmborn, Katarina et al.

Ingår i Biochimica et Biophysica Acta - General Subjects, s. 209-215, 2002

Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1

Ringvall, Maria; Ledin, Johan; Holmborn, Katarina; van Kuppevelt, Toin et al.

Ingår i Journal of Biological Chemistry, s. 25926-25930, 2000

• DOI för Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1

Abnormal mast cells in mice deficient in a heparin-sythesizing enzyme

Forsberg, Erik; Pejler, Gunnar; Ringvall, Maria; Lunderius, Carolina et al.

Ingår i Nature, s. 773-776, 1999

Biosynthesis of heparin / heparan sulfate: cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung

Li, Jin-Ping; Hagner-McWhirther, Åsa; Kjellén, Lena; Palgi, Jaan et al.

Ingår i Journal of Biological Chemistry, s. 28158-28163, 1997

• DOI för Biosynthesis of heparin / heparan sulfate: cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung

More to "heparin" than anticoagulation

Lindahl, Ulf; Lidholt, K; Spillmann, Dorothe; Kjellén, Lena

Ingår i Thrombosis Research, s. 1-32, 1994

In vivo regulation of liver heparan sulfate biosynthesis in NDST1 and NDST2 deficient mice

Ledin, Johan; Ringvall, Maria; Eriksson, Inger; Wilén, Maria et al.

Heparan Sulfate Biosynthesis in Zebrafish

Gorniok, Beata Filipek; Habicher, Judith; Ledin, Johan; Kjellén, Lena

Ingår i Journal of Histochemistry and Cytochemistry, s. 49-60, 2021

• DOI för Heparan Sulfate Biosynthesis in Zebrafish

Pathophysiology of heparan sulphate: many diseases, few drugs

Lindahl, Ulf; Kjellén, Lena

Ingår i Journal of Internal Medicine, s. 555-571, 2013

• DOI för Pathophysiology of heparan sulphate: many diseases, few drugs
• Ladda ner fulltext (pdf) av Pathophysiology of heparan sulphate: many diseases, few drugs

Mice deficient in heparan sulfate N-deacetylase/N-sulfotransferase 1.

Ringvall, Maria; Kjellén, Lena

Ingår i Progress in molecular biology and translational science, s. 35-58, 2010

• DOI för Mice deficient in heparan sulfate N-deacetylase/N-sulfotransferase 1.

Heparan sulfate expression is critical in vascular development

Jakobsson, L; Lundin, Lars; Holmborn, Katarina; Kjellén, Lena et al.

Several processes in skeletal development are affected by altered heparan sulfate structure

Ringvall, Maria; Forsberg, Erik; Kjellén, Lena

Mice lacking N-deacetylase/N-sulfotransferase 1 and 2 are defective in early postimplantation development

Holmborn, Katarina; Ringvall, Maria; Forsberg, Erik; Kjellén, Lena

Impaired mast cell development in N-deacetylase/N-sulfotransferase deficient embryonic stem cells

Holmborn, Katarina; Kjellén, Lena; Åbrink, Magnus

EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation

Presto, Jenny; Thuveson, Maria; Busse, Marta; Eriksson, Inger et al.

Effects of wild-type and mutant EXT2 on heparan sulfate chain length

Wilén, Maria; Presto, Jenny; Kjellén, Lena; Kusche-Gullberg, Marion

Heparan sulfate biosynthesis: PAPS regulates NDST-mediated formation of N-sulfated domains

Presto, Jenny; Carlsson, Pernilla; Spillmann, Dorothe; Kjellén, Lena

Heparan sulfate biosynthesis: Characterization of an NDST1 splice variant

Carlsson, Pernilla; Presto, Jenny; Kjellén, Lena

Heparan sulfate biosynthesis in zebrafish: Five NDST genes with distinct expression patterns during embryonic development

Carlsson, Pernilla; Ledin, Johan; Kjellén, Lena

Lack of both lethality and defective in vitro differentiation of embryonic stem cells N-deacetylase/N-sulfotransferase 1 and 2 causes early embryonic

Dagälv, Anders; Holmborn, Katarina; Eriksson, Inger; Ringvall, Maria et al.

Divergent effects of heparan sulfate/heparin biosynthesis enzymes N-deacetylase/N-sulfotransferase 1 and 2 on Mast cell development

Holmborn, Katarina; Dagälv, Anders; Kjellén, Lena; Åbrink, Magnus

Cell surface mast cell proteoglycans identified as heparin-substituted syndecan-2

Dagälv, Anders; Åbrink, Magnus; Kjellén, Lena

Heparan sulfate biosynthesis: Characterization of an NDST1 splice variant

Carlsson, Pernilla; Dagälv, Anders; Presto, Jenny; Kjellén, Lena

A Naked Host Cell Membrane is the Optimal Surface for Targeting by Salmonella

Geiser, Petra; Westman, Johanna; Ceylan, Merve; Bosman, Willem et al.