Sahar Roshanbin

Evaluating the impact of age and treatment on neuroinflammation-related proteins in mouse models of proteinopathies

Dahlén, Amelia; Roshanbin, Sahar; Bucher, Nadja M.; Sehlin, Dag et al.

Ingår i Experimental Neurology, 2026

• DOI för Evaluating the impact of age and treatment on neuroinflammation-related proteins in mouse models of proteinopathies
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PET imaging of TREM2 in amyloid-beta induced neuroinflammation

Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena; Bucher, Nadja et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4320-4333, 2025

• DOI för PET imaging of TREM2 in amyloid-beta induced neuroinflammation
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A brain-penetrant bispecific antibody lowers oligomeric alpha-synuclein and activates microglia in a mouse model of alpha-synuclein pathology

Sehlin, Dag; Roshanbin, Sahar; Zachrisson, Olof; Ingelsson, Martin et al.

Ingår i Neurotherapeutics, 2025

• DOI för A brain-penetrant bispecific antibody lowers oligomeric alpha-synuclein and activates microglia in a mouse model of alpha-synuclein pathology
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

Ingår i NeuroImage, 2023

• DOI för Synaptic density in aging mice measured by [18F]SynVesT-1 PET
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Evaluating the impact of age and treatment on neuroinflammation-related proteins in mouse models of proteinopathies

Dahlén, Amelia; Roshanbin, Sahar; Bucher, Nadja M.; Sehlin, Dag et al.

Ingår i Experimental Neurology, 2026

• DOI för Evaluating the impact of age and treatment on neuroinflammation-related proteins in mouse models of proteinopathies
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PET imaging of TREM2 in amyloid-beta induced neuroinflammation

Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena; Bucher, Nadja et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4320-4333, 2025

• DOI för PET imaging of TREM2 in amyloid-beta induced neuroinflammation
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A brain-penetrant bispecific antibody lowers oligomeric alpha-synuclein and activates microglia in a mouse model of alpha-synuclein pathology

Sehlin, Dag; Roshanbin, Sahar; Zachrisson, Olof; Ingelsson, Martin et al.

Ingår i Neurotherapeutics, 2025

• DOI för A brain-penetrant bispecific antibody lowers oligomeric alpha-synuclein and activates microglia in a mouse model of alpha-synuclein pathology
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

Ingår i NeuroImage, 2023

• DOI för Synaptic density in aging mice measured by [18F]SynVesT-1 PET
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Long-term effects of immunotherapy with a brain penetrating Aβ antibody in a mouse model of Alzheimer's disease

Gustavsson, Tobias; Metzendorf, Nicole G.; Wik, Elin; Roshanbin, Sahar et al.

Ingår i Alzheimer's Research & Therapy, 2023

• DOI för Long-term effects of immunotherapy with a brain penetrating Aβ antibody in a mouse model of Alzheimer's disease
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Brain pharmacokinetics of mono- and bispecific amyloid-beta antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis

Julku, Ulrika; Xiong, Mengfei; Wik, Elin; Roshanbin, Sahar et al.

Ingår i Fluids and Barriers of the CNS, 2022

• DOI för Brain pharmacokinetics of mono- and bispecific amyloid-beta antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis
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Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody

Roshanbin, Sahar; Julku, Ulrika; Xiong, Mengfei; Eriksson, Jonas et al.

Ingår i Pharmaceutics, 2022

• DOI för Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody
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In vivo imaging of alpha-synuclein with antibody-based PET

Roshanbin, Sahar; Xiong, Mengfei; Hultqvist, Greta; Soderberg, Linda et al.

Ingår i Neuropharmacology, 2022

• DOI för In vivo imaging of alpha-synuclein with antibody-based PET
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¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention

Meier, Silvio R.; Sehlin, Dag; Roshanbin, Sahar; Lim Falk, Victoria et al.

Ingår i Journal of Nuclear Medicine, s. 302-309, 2022

• DOI för ¹¹C-PiB and ¹²⁴I-antibody PET provide differing estimates of brain amyloid-β after therapeutic intervention
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Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice

Roshanbin, Sahar; Aniszewska, Agata; Gumucio, Astrid; Masliah, Eliezer et al.

Ingår i Neurobiology of Aging, s. 207-220, 2021

• DOI för Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice
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In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease

Xiong, Mengfei; Roshanbin, Sahar; Rokka, Johanna; Schlein, Eva et al.

Ingår i NeuroImage, 2021

• DOI för In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease
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The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

Fredriksson, Robert; Sreedharan, Smitha; Nordenankar, Karin; Alsiö, Johan et al.

Ingår i PLOS Genetics, 2019

• DOI för The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.
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Blood-Brain Barrier Integrity in a Mouse Model of Alzheimer’s Disease With or Without Acute 3D6 Immunotherapy

Gustafsson, Sofia; Gustavsson, Tobias; Roshanbin, Sahar; Hultqvist, Greta et al.

Ingår i Neuropharmacology, s. 1-9, 2018

• DOI för Blood-Brain Barrier Integrity in a Mouse Model of Alzheimer’s Disease With or Without Acute 3D6 Immunotherapy
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Antibody-Based In Vivo PET Imaging Detects Amyloid-beta Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition

Meier, Silvio R.; Syvänen, Stina; Hultqvist, Greta; Fang, Xiaotian T. et al.

Ingår i Journal of Nuclear Medicine, s. 1885-1891, 2018

• DOI för Antibody-Based In Vivo PET Imaging Detects Amyloid-beta Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition
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Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney

Roshanbin, Sahar; Lindberg, Frida; Lekholm, Emilia; Perland, Emelie et al.

Ingår i BMC Neuroscience, 2016

• DOI för Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney
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The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

Caruso, Vanni; Hägglund, Maria G.; Badiali, Luca; Bagchi, Sonchita et al.

Ingår i Gene, s. 1-6, 2014

• DOI för The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells

Roshanbin, Sahar; Hellsten, Sofie V; Tafreshiha, Atieh; Zhu, Yinan et al.

Ingår i Brain Research, s. 12-25, 2014

• DOI för PAT4 is abundantly expressed in excitatory and inhibitory neurons as well as epithelial cells
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B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

Hägglund, Maria G A; Roshanbin, Sahar; Löfqvist, Erik; Hellsten, Sofie V et al.

Ingår i PLOS ONE, 2013

• DOI för B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
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PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Ingår i Pharmaceutical research, s. 1481-1496, 2022

• DOI för PET Imaging in Preclinical Anti-Aβ Drug Development
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Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Schiöth, Helgi B; Roshanbin, Sahar; Hägglund, Maria G A; Fredriksson, Robert

Ingår i Molecular Aspects of Medicine, s. 571-585, 2013

• DOI för Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

Characterization of Centrally Expressed Solute Carriers: Histological and Functional Studies with Transgenic Mice

Roshanbin, Sahar

2016

• Ladda ner fulltext (pdf) av Characterization of Centrally Expressed Solute Carriers: Histological and Functional Studies with Transgenic Mice

Over the BBB and into the cell: Pursuing intracellular targets for immunotherapy of Parkinson’s disease

Stenler, Sofia; Roshanbin, Sahar; Yilmaz Ugur, Canan; Rostami, Jinar et al.

2019

Postnatal forebrain-specific deletion of neuronal transporter Slcz1

Roshanbin, Sahar; Westerfors, Elin; Sreedharan, Smitha; Schiöth, Helgi et al.

Synaptic density in aging mice measured by [¹⁸F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

[¹¹C]PiB binding after treatment with an amyloid-beta antibody

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena et al.