Mikael Engskog

Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin

Kopsida, Maria; Regtop, Lotta; Lennernäs, Hans; Hedeland, Mikael et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2025

• DOI för Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin
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Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia

Engskog-Vlachos, Pinelopi; Engskog, Mikael K R; Skandik, Martin; Grabert, Kathleen et al.

Ingår i Journal of Neurochemistry, 2025

• DOI för Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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Microglia: Agents of the CNS Pro-Inflammatory Response.

Rodríguez-Gómez, José A; Kavanagh, Edel; Engskog-Vlachos, Pinelopi; Engskog, Mikael K R et al.

Ingår i Cells, 2020

• DOI för Microglia: Agents of the CNS Pro-Inflammatory Response.
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Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling

Lindell Jonsson, Eva; Erngren, Ida; Engskog, Mikael; Haglöf, Jakob et al.

Ingår i Frontiers in Oncology, 2019

• DOI för Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling
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An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

Pirttilä, Kristian; Pierre, Pernilla Videhult; Haglöf, Jakob; Engskog, Mikael et al.

Ingår i Metabolomics, 2019

• DOI för An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs
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Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin

Kopsida, Maria; Regtop, Lotta; Lennernäs, Hans; Hedeland, Mikael et al.

Ingår i Journal of Pharmaceutical and Biomedical Analysis, 2025

• DOI för Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin
• Ladda ner fulltext (pdf) av Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin

Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia

Engskog-Vlachos, Pinelopi; Engskog, Mikael K R; Skandik, Martin; Grabert, Kathleen et al.

Ingår i Journal of Neurochemistry, 2025

• DOI för Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
• Ladda ner fulltext (pdf) av Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia

Microglia: Agents of the CNS Pro-Inflammatory Response.

Rodríguez-Gómez, José A; Kavanagh, Edel; Engskog-Vlachos, Pinelopi; Engskog, Mikael K R et al.

Ingår i Cells, 2020

• DOI för Microglia: Agents of the CNS Pro-Inflammatory Response.
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Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling

Lindell Jonsson, Eva; Erngren, Ida; Engskog, Mikael; Haglöf, Jakob et al.

Ingår i Frontiers in Oncology, 2019

• DOI för Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling
• Ladda ner fulltext (pdf) av Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling

An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

Pirttilä, Kristian; Pierre, Pernilla Videhult; Haglöf, Jakob; Engskog, Mikael et al.

Ingår i Metabolomics, 2019

• DOI för An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs
• Ladda ner fulltext (pdf) av An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs

Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples

Erngren, Ida; Haglöf, Jakob; Engskog, Mikael K R; Nestor, Marika et al.

Ingår i Journal of Chromatography A, s. 174-182, 2019

• DOI för Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples

Method selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC stationary phase performance for the analysis of plasma, urine and cell extracts.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael K R; Erngren, Ida et al.

Ingår i Journal of Chromatography A, s. 49-56, 2018

• DOI för Method selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC stationary phase performance for the analysis of plasma, urine and cell extracts.

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

Häggblad Sahlberg, Sara; Mortensen, Anja C.; Haglöf, Jakob; Engskog, Mikael K. R. et al.

Ingår i International Journal of Oncology, s. 5-14, 2017

• DOI för Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells
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β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling

Engskog, Mikael K. R.; Ersson, Lisa; Haglöf, Jakob; Arvidsson, Torbjörn et al.

Ingår i Amino Acids, s. 905-919, 2017

• DOI för β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling
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Cisplatin-induced metabolome changes in serum: an experimental approach to identify markers for ototoxicity

Pierre, Pernilla Videhult; Haglöf, Jakob; Linder, Birgitta; Engskog, Mikael K R et al.

Ingår i Acta Oto-Laryngologica, s. 1024-1030, 2017

• DOI för Cisplatin-induced metabolome changes in serum: an experimental approach to identify markers for ototoxicity

The co-feature ratio, a novel method for the measurement of chromatographic and signal selectivity in LC-MS-based metabolomics.

Elmsjö, Albert; Haglöf, Jakob; Engskog, Mikael K. R.; Nestor, Marika et al.

Ingår i Analytica Chimica Acta, s. 40-47, 2017

• DOI för The co-feature ratio, a novel method for the measurement of chromatographic and signal selectivity in LC-MS-based metabolomics.

TAp73 is a marker of glutamine addiction in medulloblastoma

Niklison-Chirou, Maria Victoria; Erngren, Ida; Engskog, Mikael K R; Haglöf, Jakob et al.

Ingår i Genes & Development, s. 1738-1753, 2017

• DOI för TAp73 is a marker of glutamine addiction in medulloblastoma
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NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.

Elmsjö, Albert; Rosqvist, Fredrik; Engskog, Mikael K R; Haglöf, Jakob et al.

Ingår i Nutrition & Diabetes, 2015

• DOI för NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.
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Metabolic profiling of epithelial ovarian cancer cell lines: evaluation of harvesting protocols for profiling using NMR spectroscopy

Engskog, Mikael K R; Björklund, My; Haglöf, Jakob; Arvidsson, Torbjörn et al.

Ingår i Bioanalysis, s. 157-166, 2015

• DOI för Metabolic profiling of epithelial ovarian cancer cell lines: evaluation of harvesting protocols for profiling using NMR spectroscopy

NMR spectroscopy based metabolic profiling of drug induced changes in vitro can discriminate between pharmacological classes

Aftab, Obaid; Engskog, Mikael; Haglöf, Jakob; Elmsjö, Albert et al.

Ingår i Journal of chemical information and modeling, s. 3251-3258, 2014

• DOI för NMR spectroscopy based metabolic profiling of drug induced changes in vitro can discriminate between pharmacological classes

The cyanobacterial amino acid beta-N-methylamino-L-alanine perturbs the intermediary metabolism in neonatal rats

Engskog, Mikael K R; Karlsson, Oskar; Haglöf, Jakob; Elmsjö, Albert et al.

Ingår i Amino Acids, s. 905-919, 2013

• DOI för The cyanobacterial amino acid beta-N-methylamino-L-alanine perturbs the intermediary metabolism in neonatal rats

LC-MS based global metabolite profiling: the necessity of high data quality

Engskog, Mikael K. R.; Haglöf, Jakob; Arvidsson, Torbjörn; Pettersson, Curt

Ingår i Metabolomics, 2016

• DOI för LC-MS based global metabolite profiling: the necessity of high data quality

Evaluation of harvesting protocols for metabolic profiling of epithelial ovarian cancer cells

Engskog, Mikael K R; Haglöf, Jakob; Arvidsson, Torbjörn; Pettersson, Curt

2014

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Ototoxicity of Cisplatin Correlates with Changes in Blood Antioxidant Status

Videhult Pierre, Pernilla; Haglöf, Jakob; Linder, Birgitta; Engskog, Mikael K R et al.

2014