Anthony Forster
Professor vid Institutionen för cell- och molekylärbiologi; Molekylärbiologi
- Telefon:
- 018-471 46 18
- E-post:
- anthony.forster@icm.uu.se
- Besöksadress:
- Husargatan 3
752 37 Uppsala - Postadress:
- Box 596
751 24 Uppsala
Kort presentation
Biografi
Anthony C. Forster (Ph.D. Biochem., U. Adelaide; M.D., Harvard U.) heads the Program in Molecular Biology at the Department of Cell and Molecular Biology and researches RNA, protein synthesis and applications thereof (synthetic biology). He discovered the hammerhead catalytic RNA structure, invented external guide sequences for ribonuclease P, and created unnatural genetic codes de novo, all of which founded biotech companies. He has published in journals including Cell, Nature and Science, edited volumes of Methods and Biotechnology J., and coauthored "Synthetic Biology: A Lab Manual."

Publikationer
Senaste publikationer
-
Synthetic biology: A lab manual
World Scientific, 2025
-
Fast peptide bond formation and release by the ribosomal large subunit
Ingår i Journal of Biological Chemistry, 2025
- DOI för Fast peptide bond formation and release by the ribosomal large subunit
- Ladda ner fulltext (pdf) av Fast peptide bond formation and release by the ribosomal large subunit
-
Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre
Ingår i RNA Biology, s. 31-41, 2024
- DOI för Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre
- Ladda ner fulltext (pdf) av Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre
-
Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
Ingår i Journal of Biological Chemistry, 2022
- DOI för Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
- Ladda ner fulltext (pdf) av Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
-
Ingår i RNA, s. 796-807, 2022
Alla publikationer
Artiklar i tidskrift
-
Fast peptide bond formation and release by the ribosomal large subunit
Ingår i Journal of Biological Chemistry, 2025
- DOI för Fast peptide bond formation and release by the ribosomal large subunit
- Ladda ner fulltext (pdf) av Fast peptide bond formation and release by the ribosomal large subunit
-
Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre
Ingår i RNA Biology, s. 31-41, 2024
- DOI för Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre
- Ladda ner fulltext (pdf) av Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre
-
Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
Ingår i Journal of Biological Chemistry, 2022
- DOI för Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
- Ladda ner fulltext (pdf) av Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
-
Ingår i RNA, s. 796-807, 2022
-
Revisiting the Extinction of the RNA World
Ingår i Biochemistry, s. 749-751, 2022
- DOI för Revisiting the Extinction of the RNA World
- Ladda ner fulltext (pdf) av Revisiting the Extinction of the RNA World
-
Tales of the unexpected in Sidney Altman's laboratory
Ingår i RNA, s. 1406-1408, 2022
-
Ingår i Scientific Reports, 2021
- DOI för In vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity
- Ladda ner fulltext (pdf) av In vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity
-
Overcoming chromoprotein limitations by engineering a red fluorescent protein
Ingår i Analytical Biochemistry, 2020
- DOI för Overcoming chromoprotein limitations by engineering a red fluorescent protein
- Ladda ner fulltext (pdf) av Overcoming chromoprotein limitations by engineering a red fluorescent protein
-
Ingår i ENGINEERING REPORTS, 2020
- DOI för Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli
- Ladda ner fulltext (pdf) av Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli
-
Kinetics of D-amino acid incorporation in translation
Ingår i ACS Chemical Biology, s. 204-213, 2019
-
Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology
Ingår i Journal of Biological Engineering, 2018
- DOI för Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology
- Ladda ner fulltext (pdf) av Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology
-
De novo design and synthesis of a 30-cistron translation-factor module
Ingår i Nucleic Acids Research, s. 10895-10905, 2017
- DOI för De novo design and synthesis of a 30-cistron translation-factor module
- Ladda ner fulltext (pdf) av De novo design and synthesis of a 30-cistron translation-factor module
-
Ingår i Scientific Reports, 2017
- DOI för Translational roles of the C75 2 ' OH in an in vitro tRNA transcript at the ribosomal A, P and E sites
- Ladda ner fulltext (pdf) av Translational roles of the C75 2 ' OH in an in vitro tRNA transcript at the ribosomal A, P and E sites
-
Ingår i Biotechnology and Bioengineering, s. 1552-1559, 2016
-
Ingår i Journal of the American Chemical Society, s. 15587-15595, 2016
-
Ingår i ACS Chemical Biology, s. 2187-2192, 2015
-
Peptide Formation by N-Methyl Amino Acids in Translation Is Hastened by Higher pH and tRNAPro
Ingår i ACS Chemical Biology, s. 1303-1311, 2014
-
Facile Synthesis of N-Acyl-aminoacyl-pCpA for Preparation of Mischarged Fully Ribo tRNA
Ingår i Bioconjugate chemistry, s. 2086-2091, 2014
-
A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids
Ingår i RNA, s. 632-643, 2014
- DOI för A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids
- Ladda ner fulltext (pdf) av A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids
-
Differential Translation Tunes Uneven Production of Operon-Encoded Proteins
Ingår i Cell Reports, s. 938-944, 2013
- DOI för Differential Translation Tunes Uneven Production of Operon-Encoded Proteins
- Ladda ner fulltext (pdf) av Differential Translation Tunes Uneven Production of Operon-Encoded Proteins
-
Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
Ingår i Nucleic Acids Research, s. 9537-9548, 2013
- DOI för Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
- Ladda ner fulltext (pdf) av Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
-
Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA
Ingår i Nucleic Acids Research, s. 10507-20, 2012
- DOI för Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA
- Ladda ner fulltext (pdf) av Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA
-
Multigene expression in vivo: Supremacy of large versus small terminators for T7 RNA polymerase
Ingår i Biotechnology and Bioengineering, s. 1043-1050, 2012
-
Editorial: NextGen SynBio has arrived...
Ingår i Biotechnology Journal, s. 827-827, 2012
-
Inefficient delivery but fast peptide bond formation of unnatural l -aminoacyl-tRNAs in translation
Ingår i Journal of the American Chemical Society, s. 17955-17962, 2012
-
Multiplexed in Vivo His-Tagging of Enzyme Pathways for in Vitro Single-Pot Multienzyme Catalysis
Ingår i ACS Synthetic Biology, s. 43-52, 2012
Artiklar, forskningsöversikt
-
Ingår i Current opinion in chemical biology, s. 180-187, 2018
-
Synthetic biology challenges long-held hypotheses in translation, codon bias and transcription
Ingår i Biotechnology Journal, s. 835-845, 2012
-
Update on pure translation display with unnatural amino acid incorporation
Ingår i Methods in Molecular Biology, s. 349-365, 2012
Böcker
-
Synthetic biology: A lab manual
World Scientific, 2025
-
Synthetic Biology: A Lab Manual
World Scientific, 2014