Viktor Ljungström

Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

Vasaitis, Lilian; Blomstrand, Lena; Pandzic, Tatjana; Gulyas, Miklos et al.

Ingår i Rheumatology & Autoimmunity, s. 60-62, 2026

• DOI för Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome
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Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms

Nadeu, Ferran; Shuai, Shimin; Clot, Guillem; Hilton, Laura K. et al.

Ingår i Leukemia, s. 2076-2086, 2025

• DOI för Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms
• Ladda ner fulltext (pdf) av Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms

Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib

Zhang, Xiaonan; Rameika, Natallia; Zhong, Lei; Veanes, Margus et al.

Ingår i EBioMedicine, 2024

• DOI för Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib
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Prognostic genome and transcriptome signatures in colorectal cancers

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; Luo, Tian et al.

Ingår i Nature, s. 137-146, 2024

• DOI för Prognostic genome and transcriptome signatures in colorectal cancers
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The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia

Hagerstrand, Daniel; Oder, Blaz; Cortese, Diego; Qu, Ying et al.

Ingår i Leukemia, s. 2429-2442, 2024

• DOI för The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia
• Ladda ner fulltext (pdf) av The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia

Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

Vasaitis, Lilian; Blomstrand, Lena; Pandzic, Tatjana; Gulyas, Miklos et al.

Ingår i Rheumatology & Autoimmunity, s. 60-62, 2026

• DOI för Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome
• Ladda ner fulltext (pdf) av Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms

Nadeu, Ferran; Shuai, Shimin; Clot, Guillem; Hilton, Laura K. et al.

Ingår i Leukemia, s. 2076-2086, 2025

• DOI för Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms
• Ladda ner fulltext (pdf) av Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms

Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib

Zhang, Xiaonan; Rameika, Natallia; Zhong, Lei; Veanes, Margus et al.

Ingår i EBioMedicine, 2024

• DOI för Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib
• Ladda ner fulltext (pdf) av Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib

Prognostic genome and transcriptome signatures in colorectal cancers

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; Luo, Tian et al.

Ingår i Nature, s. 137-146, 2024

• DOI för Prognostic genome and transcriptome signatures in colorectal cancers
• Ladda ner fulltext (pdf) av Prognostic genome and transcriptome signatures in colorectal cancers

The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia

Hagerstrand, Daniel; Oder, Blaz; Cortese, Diego; Qu, Ying et al.

Ingår i Leukemia, s. 2429-2442, 2024

• DOI för The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia
• Ladda ner fulltext (pdf) av The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia

BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib

Bonfiglio, Silvia; Sutton, Lesley-Ann; Ljungström, Viktor; Capasso, Antonella et al.

Ingår i Blood Advances, s. 2794-2806, 2023

• DOI för BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib
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Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?

Ljungström, Viktor; Mattisson, Jonas; Halvardson, Jonatan; Pandzic, Tatjana et al.

Ingår i Leukemia, s. 889-891, 2022

• DOI för Loss of Y and clonal hematopoiesis in blood: two sides of the same coin?
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Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations

Tausch, Eugen; Ljungström, Viktor; Agathangelidis, Andreas; Zapatka, Marc et al.

Ingår i Blood, s. 3340-3344, 2022

• DOI för Secondary resistance to idelalisib is characterized by upregulation of IGF1R rather than by MAPK/ERK pathway mutations

Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy

Voso, Maria-Teresa; Pandzic, Tatjana; Falconi, Giulia; Dencic-Fekete, Marija et al.

Ingår i British Journal of Haematology, s. 103-113, 2022

• DOI för Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy

Familial platelet disorder due to germline exonic deletions in RUNX1: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium

Engvall, Marie; Karlsson, Ylva; Kuchinskaya, Ekaterina; Jörnegren, Åsa et al.

Ingår i Leukemia and Lymphoma, s. 2311-2320, 2022

• DOI för Familial platelet disorder due to germline exonic deletions in RUNX1: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium
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Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting

Pandzic, Tatjana; Ladenvall, Claes; Engvall, Marie; Mattsson, Mattias et al.

Ingår i HemaSphere, 2022

• DOI för Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting
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Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia

Kolijn, P. Martijn; Muggen, Alice F.; Ljungström, Viktor; Agathangelidis, Andreas et al.

Ingår i Frontiers in Oncology, 2021

• DOI för Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia
• Ladda ner fulltext (pdf) av Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia

Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study

Sutton, Lesley-Ann; Ljungström, Viktor; Enjuanes, Anna; Cortese, Diego et al.

Ingår i Haematologica, s. 682-691, 2021

• DOI för Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
• Ladda ner fulltext (pdf) av Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study

Prognostic and Predictive Implications of Cytogenetics and Genomics

Ljungström, Viktor; Baliakas, Panagiotis

Ingår i Hematology/Oncology Clinics of North America, s. 703-713, 2021

• DOI för Prognostic and Predictive Implications of Cytogenetics and Genomics
• Ladda ner fulltext (pdf) av Prognostic and Predictive Implications of Cytogenetics and Genomics

A single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib

Maffei, Rossana; Fiorcari, Stefania; Atene, Claudio Giacinto; Martinelli, Silvia et al.

Ingår i Leukemia and Lymphoma, s. 2018-2021, 2021

• DOI för A single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib

Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer

Rendo, Verónica; Kundu, Snehangshu; Rameika, Natallia; Ljungström, Viktor et al.

Ingår i Scientific Reports, 2020

• DOI för Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer
• Ladda ner fulltext (pdf) av Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer

Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Nunes, Luís; Aasebø, Kristine; Mathot, Lucy; Ljungström, Viktor et al.

Ingår i Acta Oncologica, s. 417-426, 2020

• DOI för Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
• Ladda ner fulltext (pdf) av Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort

Mathioudaki, Argyri; Ljungström, Viktor; Melin, Malin; Arendt, Maja Louise et al.

Ingår i Scientific Reports, 2020

• DOI för Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort
• Ladda ner fulltext (pdf) av Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort

Clonal hematopoiesis in patients with high-grade B-cell lymphoma is associated with inferior outcome

Amini, Rose-Marie; Ljungström, Viktor; Abdulla, Maysaa; Cavelier, Lucia et al.

Ingår i American Journal of Hematology, 2020

• DOI för Clonal hematopoiesis in patients with high-grade B-cell lymphoma is associated with inferior outcome
• Ladda ner fulltext (pdf) av Clonal hematopoiesis in patients with high-grade B-cell lymphoma is associated with inferior outcome

DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy

Tsagiopoulou, Maria; Papakonstantinou, Nikos; Moysiadis, Theodoros; Mansouri, Larry et al.

Ingår i Clinical Epigenetics, 2019

• DOI för DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy
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Not so lost in translation: RPS15 mutations in CLL

Ljungström, Viktor; Rosenquist, Richard

Ingår i Blood, s. 2317-2319, 2018

• DOI för Not so lost in translation: RPS15 mutations in CLL

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

Agathangelidis, Andreas; Ljungström, Viktor; Scarfo, Lydia; Fazi, Claudia et al.

Ingår i Haematologica, s. 865-873, 2018

• DOI för Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
• Ladda ner fulltext (pdf) av Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

Mathot, Lucy; Kundu, Snehangshu; Ljungström, Viktor; Svedlund, Jessica et al.

Ingår i Cancer Research, s. 1730-1740, 2017

• DOI för Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

Transcriptome sequencing provides novel insights into the biology of chronic lymphocytic leukemia: focus on major stereotyped subsets

Sutton, Lesley Ann; Cortese, Diego; Ljungström, Viktor; Plevova, Karla et al.

Ingår i Leukemia and Lymphoma, s. 220-221, 2017

• DOI för Transcriptome sequencing provides novel insights into the biology of chronic lymphocytic leukemia: focus on major stereotyped subsets

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia

Young, Emma; Noerenberg, Daniel; Mansouri, Larry; Ljungström, Viktor et al.

Ingår i Leukemia, s. 1547-1554, 2017

• DOI för EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

Mansouri, Larry; Noerenberg, Daniel; Young, Emma; Mylonas, Elena et al.

Ingår i Blood, s. 2666-2670, 2016

• DOI för Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2

Bhoi, Sujata; Ljungström, Viktor; Baliakas, Panagiotis; Mattsson, Mattias et al.

Ingår i Epigenetics, s. 449-455, 2016

• DOI för Prognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Ljungström, Viktor; Cortese, Diego; Young, Emma; Pandzic, Tatjana et al.

Ingår i Blood, s. 1007-1016, 2016

• DOI för Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia

Parker, H.; Rose-Zerilli, M. J. J.; Larrayoz, M.; Clifford, R. et al.

Ingår i Leukemia, s. 2179-2186, 2016

• DOI för Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
• Ladda ner fulltext (pdf) av Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia

Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia

Pandzic, Tatjana; Larsson, Jimmy; He, Liqun; Kundu, Snehangshu et al.

Ingår i Clinical Cancer Research, s. 6217-6227, 2016

• DOI för Transposon Mutagenesis Reveals Fludarabine Resistance Mechanisms in Chronic Lymphocytic Leukemia

ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

Navrkalova, Veronika; Young, Emma; Baliakas, Panagiotis; Radova, Lenka et al.

Ingår i Haematologica, 2016

• DOI för ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

Molecular Profiling In A Population Based Cohort Of Nordic Myelodysplastic Syndrome Patients

Karimi, M.; Ljungström, Viktor; Hansen, J. Werner; Kittang, A. Olsnes et al.

Ingår i Haematologica, s. 72-72, 2016

Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing

Parry, Marina; Rose-Zerilli, Matthew J. J.; Ljungström, Viktor; Gibson, Jane et al.

Ingår i Clinical Cancer Research, s. 4174-4183, 2015

• DOI för Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia

Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina et al.

Ingår i Journal of Experimental Medicine, s. 833-843, 2015

• DOI för Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
• Ladda ner fulltext (pdf) av Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia

Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting

Sutton, Lesley-Ann; Ljungström, Viktor; Mansouri, Larry; Young, Emma et al.

Ingår i Haematologica, s. 370-376, 2015

• DOI för Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting

EGR2 Mutations in Chronic Lymphocytic Leukemia: A New Bad Player

Noerenberg, Daniel; Young, Emma; Ljungström, Viktor; Mansouri, Larry et al.

Ingår i Blood, 2015

ATM Mutations in Major Stereotyped CLL Subsets: Enrichment in Subset #2 is Associated with Unfavourable Outcome

Navrkalova, Veronika; Young, Emma; Baliakas, Panagiotis; Radova, Lenka et al.

Ingår i Blood, 2015

DISSECTING RESISTANCE MECHANISMS IN CHRONIC LYMPHOCYTIC LEUKEMIA USING WHOLE-EXOME SEQUENCING: IMPACT OF RECURRENT RPS15 MUTATIONS ON P53 DYSREGULATION

Ljungström, Viktor; Cortese, Diego; Young, Emma; Pandzic, Tatjana et al.

Ingår i Haematologica, s. 10-11, 2015

EGR2 mutations in chronic lymphocytic leukemiam - a new bad player?

Young, Emma; Norenberg, Daniel; Ljungstrom, Viktor; Mansouri, Larry et al.

Ingår i Leukemia and Lymphoma, s. 83-85, 2015

Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

Kiflemariam, Sara; Ljungström, Viktor; Pontén, Fredrik; Sjöblom, Tobias

Ingår i American Journal of Pathology, s. 1600-1609, 2015

• DOI för Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

Bioinformatic Challenges in Clinical Diagnostic Application of Targeted Next Generation Sequencing: Experience from Pheochromocytoma

Crona, Joakim; Ljungström, Viktor; Welin, Staffan; Walz, Martin K. et al.

Ingår i PLOS ONE, 2015

• DOI för Bioinformatic Challenges in Clinical Diagnostic Application of Targeted Next Generation Sequencing: Experience from Pheochromocytoma
• Ladda ner fulltext (pdf) av Bioinformatic Challenges in Clinical Diagnostic Application of Targeted Next Generation Sequencing: Experience from Pheochromocytoma

HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

Moens, Lotte N. J.; Falk-Sörqvist, Elin; Ljungström, Viktor; Mattsson, Johanna et al.

Ingår i Journal of Molecular Diagnostics, s. 729-739, 2015

• DOI för HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Malcovati, Luca; Karimi, Mohsen; Papaemmanuil, Elli; Ambaglio, Ilaria et al.

Ingår i Blood, s. 233-241, 2015

• DOI för SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Rose-Zerilli, Matthew John Jerome; Parker, Helen; Larrayoz, Marta; Clifford, Ruth et al.

Ingår i Blood, 2015

Targeted Next-Generation Sequencing for Mutational Screening in Chronic Lymphocytic Leukemia: A High-Throughput Yet Tailored Approach Will Facilitate Implementation Within a Clinical Setting

Sutton, L. A.; Ljungström, Viktor; Mansouri, Larry; Young, Emma et al.

Ingår i Haematologica, s. 313-314, 2014

Recurrent Mutations within the Nfkbie gene: A Novel Mechanism for NF-kappa B Deregulation in Aggressive Chronic Lymphocytic Leukemia

Mansouri, Larry; Sutton, Lesley-Ann; Ljungström, Viktor; Bondza, Sina et al.

Ingår i Blood, 2014

Deep-Sequencing Reveals the Molecular Landscape of Splenic Marginal Zone Lymphoma: Biological and Clinical Implications

Rose-Zerilli, Matthew J. J.; Parry, Marina; Ljungström, Viktor; Gibson, Jane et al.

Ingår i Blood, 2014

Genetic Determinants of Disease Phenotype and Clinical Outcome in Myelodysplastic Syndromes with Ring Sideroblasts

Malcovati, Luca; Karimi, Mohsen; Papaemmanuil, Elli; Ambaglio, Ilaria et al.

Ingår i Blood, 2014

Hög tid att söka till nya MD/PhD-programmet vid Uppsala universitet: Tidig bro mellan preklinisk forskning och klinik

Staaf, Johan; Åkerström, Tobias; Ljungström, Viktor; Larsson, Sune et al.

Ingår i Läkartidningen, s. 898-898, 2012

Exploring next-generation sequencing in chronic lymphocytic leukemia

Ljungström, Viktor

2016

• Ladda ner fulltext (pdf) av Exploring next-generation sequencing in chronic lymphocytic leukemia

Clonal evolution patterns in high-risk chronic lymphocytic leukemia treated with ibrutinib

Mattsson, Mattias; Ljungström, Viktor; Djureinovic, Tatjana; Mansouri, Larry et al.

Whole-genome sequencing in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

Ljungström, Viktor; Young, Emma; Agathangelidis, Andreas; Muggen, Alice F. et al.

Origins of fusion genes iAMP21 and STIL::TAL1 in children who later developed paediatric acute lymphoblastic leukaemia: An investigation of neonatal blood spots.

Leijonhufvud, Gustaf; Ljungström, Viktor; Amini, Rose-Marie; Saft, Ilone et al.