Hannes Manell

Obesity-related subclinical hypothyroidism in childhood: Elevated triglycerides but not basal metabolic rate

Tersander, Beata; Olsson, Roger; Aydin, Banu K.; Stenlid, Rasmus et al.

Ingår i Pediatric Research, s. 182-187, 2025

• DOI för Obesity-related subclinical hypothyroidism in childhood: Elevated triglycerides but not basal metabolic rate
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Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Stenlid, Rasmus; El Amrani, Sami; Cerenius, Sara Y.; Aydin, Banu K. et al.

Ingår i Cardiovascular Diabetology, 2025

• DOI för Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
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Asthma diagnosis is not associated with reduced beta-cell function in children and adolescents with obesity

Manell, Hannes; Stenlid, Rasmus; Alving, Kjell

Ingår i Pediatric Allergy and Immunology, 2025

• DOI för Asthma diagnosis is not associated with reduced beta-cell function in children and adolescents with obesity
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Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Stenlid, Rasmus; El Amrani, Sami; Cerenius, Sara Y.; Aydin, Banu K. et al.

Ingår i Cardiovascular Diabetology, 2025

• DOI för Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
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Validation of Fat Mass Metrics in Pediatric Obesity

Lischka, Julia; Pixner, Thomas; Mörwald, Katharina; Lauth, Wanda et al.

Ingår i Annals of Nutrition and Metabolism, s. 12-21, 2025

• DOI för Validation of Fat Mass Metrics in Pediatric Obesity

Obesity-related subclinical hypothyroidism in childhood: Elevated triglycerides but not basal metabolic rate

Tersander, Beata; Olsson, Roger; Aydin, Banu K.; Stenlid, Rasmus et al.

Ingår i Pediatric Research, s. 182-187, 2025

• DOI för Obesity-related subclinical hypothyroidism in childhood: Elevated triglycerides but not basal metabolic rate
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Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Stenlid, Rasmus; El Amrani, Sami; Cerenius, Sara Y.; Aydin, Banu K. et al.

Ingår i Cardiovascular Diabetology, 2025

• DOI för Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
• Ladda ner fulltext (pdf) av Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Asthma diagnosis is not associated with reduced beta-cell function in children and adolescents with obesity

Manell, Hannes; Stenlid, Rasmus; Alving, Kjell

Ingår i Pediatric Allergy and Immunology, 2025

• DOI för Asthma diagnosis is not associated with reduced beta-cell function in children and adolescents with obesity
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Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Stenlid, Rasmus; El Amrani, Sami; Cerenius, Sara Y.; Aydin, Banu K. et al.

Ingår i Cardiovascular Diabetology, 2025

• DOI för Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
• Ladda ner fulltext (pdf) av Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS

Validation of Fat Mass Metrics in Pediatric Obesity

Lischka, Julia; Pixner, Thomas; Mörwald, Katharina; Lauth, Wanda et al.

Ingår i Annals of Nutrition and Metabolism, s. 12-21, 2025

• DOI för Validation of Fat Mass Metrics in Pediatric Obesity

Studies in children with obesity in two European treatment centres show a high prevalence of impaired glucose metabolism in the Swedish cohort

Ciba, Iris; Dahlbom, Marie; Manell, Hannes; Mörwald, Katharina et al.

Ingår i Acta Paediatrica, s. 286-295, 2024

• DOI för Studies in children with obesity in two European treatment centres show a high prevalence of impaired glucose metabolism in the Swedish cohort
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Multiarray screening identifies plasma proteins associated with Th17 cell differentiation and viral defense in coincident asthma and obesity

Manell, Hannes; Tsolakis, Nikolaos; Janson, Christer; Malinovschi, Andrei et al.

Ingår i Pediatric Allergy and Immunology, 2024

• DOI för Multiarray screening identifies plasma proteins associated with Th17 cell differentiation and viral defense in coincident asthma and obesity
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Biomarker screening in children and adolescents reveals that CUB domain-containing protein 1 is associated with obesity and that hepatocyte growth factor is associated with weight gain

Manell, Hannes; Shen, Qiujin; Chowdhury, Azazul Islam; Roomp, Kirsten et al.

Ingår i Obesity Medicine, 2023

• DOI för Biomarker screening in children and adolescents reveals that CUB domain-containing protein 1 is associated with obesity and that hepatocyte growth factor is associated with weight gain
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Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control

Stenlid, Rasmus; Cerenius, Sara Y.; Wen, Quan; Aydin, Banu K. et al.

Ingår i Frontiers in Endocrinology, 2023

• DOI för Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control
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Screening for inflammatory markers identifies IL18-Rα as a potential link between exenatide and its anti-inflammatory effect: New results from the Combat-JUDO randomized controlled trial

Stenlid, Rasmus; Cerenius, Sara Y.; Manell, Hannes; Aydin, Banu K. et al.

Ingår i Annals of Nutrition and Metabolism, s. 522-527, 2023

• DOI för Screening for inflammatory markers identifies IL18-Rα as a potential link between exenatide and its anti-inflammatory effect: New results from the Combat-JUDO randomized controlled trial

Low Fasting Concentrations of Glucagon in Patients with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency

Stenlid, Rasmus; Manell, Hannes; Seth, Rikard; Cerenius, Sara Y. et al.

Ingår i Metabolites, 2023

• DOI för Low Fasting Concentrations of Glucagon in Patients with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
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Metformin Can Attenuate Beta-Cell Hypersecretion-Implications for Treatment of Children with Obesity

Wen, Quan; Stenlid, Rasmus; Chowdhury, Azazul Islam; Ciba, Iris et al.

Ingår i Metabolites, 2023

• DOI för Metformin Can Attenuate Beta-Cell Hypersecretion-Implications for Treatment of Children with Obesity
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Altered mitochondrial metabolism in peripheral blood cells from patients with inborn errors of β-oxidation

Stenlid, Rasmus; Olsson, David; Cen, Jing; Manell, Hannes et al.

Ingår i Clinical and Translational Science, s. 182-194, 2022

• DOI för Altered mitochondrial metabolism in peripheral blood cells from patients with inborn errors of β-oxidation
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Determinants of hyperglucagonemia in pediatric non-alcoholic fatty liver disease

Maruszczak, Katharina; Radzikowski, Konrad; Schuetz, Sebastian; Mangge, Harald et al.

Ingår i Frontiers in Endocrinology, 2022

• DOI för Determinants of hyperglucagonemia in pediatric non-alcoholic fatty liver disease
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Single Point Insulin Sensitivity Estimator in Pediatric Non-Alcoholic Fatty Liver Disease

Furthner, Dieter; Anderwald, Christian-Heinz; Bergsten, Peter; Forslund, Anders et al.

Ingår i Frontiers in Endocrinology, 2022

• DOI för Single Point Insulin Sensitivity Estimator in Pediatric Non-Alcoholic Fatty Liver Disease
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Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.

Mörwald, Katharina; Aigner, Elmar; Bergsten, Peter; Brunner, Susanne M et al.

Ingår i Frontiers in Endocrinology, 2020

• DOI för Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.

A 6-month randomized, double-blind, placebo-controlled trial of weekly exenatide in adolescents with obesity

Weghuber, D.; Forslund, Anders; Ahlström, Håkan; Alderborn, Anders et al.

Ingår i Pediatric Obesity, 2020

• DOI för A 6-month randomized, double-blind, placebo-controlled trial of weekly exenatide in adolescents with obesity
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Brown adipose tissue estimated with the magnetic resonance imaging fat fraction is associated with glucose metabolism in adolescents

Lundström, Elin; Ljungberg, Joy; Andersson, Jonathan; Manell, Hannes et al.

Ingår i Pediatric Obesity, 2019

• DOI för Brown adipose tissue estimated with the magnetic resonance imaging fat fraction is associated with glucose metabolism in adolescents

Hyperglucagonemia in youth is associated with high plasma free fatty acids, visceral adiposity and impaired glucose tolerance

Manell, Hannes; Kristinsson, Hjalti; Kullberg, Joel; Ubhayasekera, Sarojini Jayantha Kumari et al.

Ingår i Pediatric Diabetes, s. 880-891, 2019

• DOI för Hyperglucagonemia in youth is associated with high plasma free fatty acids, visceral adiposity and impaired glucose tolerance

High DPP-4 concentrations in adolescents are associated with low intact GLP-1

Stenlid, Rasmus; Manell, Hannes; Halldin, Maria; Kullberg, Joel et al.

Ingår i Journal of Clinical Endocrinology and Metabolism, s. 2958-2966, 2018

• DOI för High DPP-4 concentrations in adolescents are associated with low intact GLP-1

The initial rise in GIP secretion during OGTT correlates with the initial suppression of glucagon secretion in adolescents with obesity and type 2 diabetes

Kristinsson, Hjalti; Manell, Hannes; Dahlbom, Marie; Presto, J. et al.

Ingår i Diabetologia, 2018

Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

Kristinsson, Hjalti; Sargsyan, Ernest; Manell, Hannes; Smith, D. M. et al.

Ingår i Scientific Reports, 2017

• DOI för Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism

Roomp, Kirsten; Kristinsson, Hjalti; Schvartz, Domitille; Ubhayasekera, Kumari et al.

Ingår i PLOS ONE, 2017

• DOI för Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism
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Association Between Non-Alcoholic Fatty Liver Disease (NAFLD) and Iron Metabolism in Obese Children and Adolescents: Results of the Beta-JUDO Study

Paulmichl, K.; Ahlström, Håkan; Bergsten, Peter; Brunner, S. et al.

Ingår i Acta Paediatrica, s. 13-13, 2017

• DOI för Association Between Non-Alcoholic Fatty Liver Disease (NAFLD) and Iron Metabolism in Obese Children and Adolescents: Results of the Beta-JUDO Study

Exenatide Once Weekly Reduces Weight, Liver Fat And 2-Hour Postprandial Glucose In Obese Adolescents

Forslund, Anders; Weghuber, D.; Paulmichl, K.; Zsoldos, F. et al.

Ingår i Acta Paediatrica, s. 14-15, 2017

• DOI för Exenatide Once Weekly Reduces Weight, Liver Fat And 2-Hour Postprandial Glucose In Obese Adolescents

Effect of Glucose Load on the Incretin Response (GLP-1) in obese Adolescents compared to the normal-weight Adolescents

Heu, Verena; Aigner, Elmar; Bergsten, Peter; Cadamuro, Janne et al.

Ingår i Wiener Klinische Wochenschrift, s. 736-736, 2017

TNFSF14: a potential contributor to hyperinsulinaemia in childhood obesity

Manell, Hannes; Shen, Qiujin; Kamali-Moghaddam, Masood; Forslund, Anders et al.

Ingår i Diabetologia, 2017

Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity

Staaf, Johan; Labmayr, Viktor; Paulmichl, Katharina; Manell, Hannes et al.

Ingår i Pancreas, s. 358-365, 2017

• DOI för Pancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity
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Altered Plasma Levels of Glucagon, GLP-1 and Glicentin During OGTT in Adolescents With Obesity and Type 2 Diabetes

Manell, Hannes; Staaf, Johan; Manukyan, Levon; Kristinsson, Hjalti et al.

Ingår i Journal of Clinical Endocrinology and Metabolism, s. 1181-1189, 2016

• DOI för Altered Plasma Levels of Glucagon, GLP-1 and Glicentin During OGTT in Adolescents With Obesity and Type 2 Diabetes

Hyperglucagonemia is associated with a Increase of Plasma Triglycerides as well as visceral Fat Tissue in a pediatric Cohort

Manell, Hannes; Kristinsson, Hjalti; Kullberg, Joel; Paulmichl, Katharina et al.

Ingår i Wiener Klinische Wochenschrift, s. 747-747, 2016

Initial hyperinsulinemia and subsequent beta-cell dysfunction is associated with elevated palmitate levels

Staaf, Johan; Ubhayasekera, Sarojini J. K. A.; Sargsyan, Ernest; Chowdhury, Azazul et al.

Ingår i Pediatric Research, s. 267-274, 2016

• DOI för Initial hyperinsulinemia and subsequent beta-cell dysfunction is associated with elevated palmitate levels

Modification and Validation of the Triglyceride-to-HDL Cholesterol Ratio as a Surrogate of Insulin Sensitivity in White Juveniles and Adults without Diabetes Mellitus: The Single Point Insulin Sensitivity Estimator (SPISE)

Paulmichl, Katharina; Hatunic, Mensud; Hojlund, Kurt; Jotic, Aleksandra et al.

Ingår i Clinical Chemistry, s. 1211-1219, 2016

• DOI för Modification and Validation of the Triglyceride-to-HDL Cholesterol Ratio as a Surrogate of Insulin Sensitivity in White Juveniles and Adults without Diabetes Mellitus: The Single Point Insulin Sensitivity Estimator (SPISE)

Hyperglucagonaemia is associated with elevated plasma triglycerides and increased visceral fat in children and adolescents

Manell, Hannes; Kristinsson, Hjalti; Kullberg, Joel; Paulmichl, K. et al.

Ingår i Diabetologia, 2016

Early Adiposity Rebound and its Association with Obesity and Neuropsychiatric Disorders

Norgren, A.; Ciba, Iris; Manell, Hannes; Stenlid, R. et al.

Ingår i Acta Paediatrica, s. 16-16, 2015

Development of Glucose Intolerance in Obese Children Studied in the Beta-Judo Cohort

Ciba, Iris; Weghuber, D.; Manell, Hannes; Staaf, Johan et al.

Ingår i Acta Paediatrica, s. 12-12, 2015

Dipeptidyl Peptidase-4 is Associated with Elevated Liver Enzymes, Impaired Glucose Tolerance and Lowered Glucagon-Like Peptide-1 in Obese Children

Stenlid, R.; Manell, Hannes; Forslund, Anders; Bergsten, Peter

Ingår i Acta Paediatrica, s. 15-15, 2015

Medical students' knowledge, attitudes and perceptions towards contraceptive use and counselling: a cross-sectional survey in Maharashtra, India.

Hogmark, Sara; Klingberg-Allvin, Marie; Gemzell-Danielsson, Kristina; Ohlsson, Hannes et al.

Ingår i BMJ Open, 2013

• DOI för Medical students' knowledge, attitudes and perceptions towards contraceptive use and counselling: a cross-sectional survey in Maharashtra, India.

The GLP-1 receptor agonist exenatide is associated with improved adherence to health behavior and lifestyle treatment in adolescents with obesity, results from a randomized controlled trial

Stenlid, Rasmus; Cerenius, Sara Y.; Torbahn, Gabriel; Aydin, Banu K. et al.

Fasting insulin better predicts cardiometabolic risk factors in children and adolescents with obesity than BMI

Stenlid, Rasmus; El Amrani, Sami; Cerenius, Sara Y.; Aydin, Banu K. et al.

Impaired Glucose Tolerance in Childhood Obesity: Contribution of Glucagon, GLP-1 and Inflammation

Manell, Hannes

2019

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Screening of inflammatory markers finds hepatocyte growth factor to be associated with weight gain in children and adolescents with obesity

Manell, Hannes; Shen, Qiujin; Roomp, Kirsten; Ciba, Iris et al.

Histamine-N-methyltransferase as a Novel Indicator of Beta-Cell Stress in Pediatric Obesity

Ciba, Iris; Manell, Hannes; Klintman, Elin; Aydin, Banu K. et al.

The metformin intervention (MINT) study – a randomized trial for the treatment of pediatric obesity

Ciba, Iris; Manell, Hannes; Andersson, Kerstin; Aydin, Banu K. et al.