Samuel Backman

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Zhou, Junhua; Azizan, Elena A. B.; Cabrera, Claudia P.; Fernandes-Rosa, Fabio L. et al.

Ingår i Nature Genetics, s. 1360-1372, 2021

• DOI för Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Whole genome sequencing of apparently mutation-negative MEN1 patients

Backman, Samuel; Bajic, Duska; Crona, Joakim; Hellman, Per et al.

Ingår i European Journal of Endocrinology, s. 35-45, 2020

• DOI för Whole genome sequencing of apparently mutation-negative MEN1 patients

Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Crona, Joakim; Backman, Samuel; Maharjan, Rajani; Mayrhofer, Markus et al.

Ingår i Clinical Cancer Research, s. 4451-4460, 2015

• DOI för Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Methylation profiling reveals epigenetic programs associated with chr18 loss in small intestinal neuroendocrine tumors

Axling, Fredrik; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Ingår i Frontiers in Oncology, 2026

• DOI för Methylation profiling reveals epigenetic programs associated with chr18 loss in small intestinal neuroendocrine tumors
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Single-Cell Comparison of Small Intestinal Neuroendocrine Tumors and Enterochromaffin Cells from Two Patients

Axling, Fredrik; Barazeghi, Elham; Hellman, Per; Norlén, Olov et al.

Ingår i Cancers, s. 435-435, 2026

• DOI för Single-Cell Comparison of Small Intestinal Neuroendocrine Tumors and Enterochromaffin Cells from Two Patients
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Metformin inhibits small intestinal neuroendocrine tumor growth in vivo

Axling, Fredrik; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Ingår i BMC Cancer, 2026

• DOI för Metformin inhibits small intestinal neuroendocrine tumor growth in vivo
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Genomic Catastrophe Defines the Evolutionary Trajectory of Adrenocortical Carcinoma

Backman, Samuel; Axling, Fredrik; Zhang, Liang; Botling, Johan et al.

Ingår i Endocrine pathology, 2026

• DOI för Genomic Catastrophe Defines the Evolutionary Trajectory of Adrenocortical Carcinoma
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Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors

Barazeghi, Elham; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Ingår i Endocrine Connections, 2025

• DOI för Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors
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Methylation profiling reveals epigenetic programs associated with chr18 loss in small intestinal neuroendocrine tumors

Axling, Fredrik; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Ingår i Frontiers in Oncology, 2026

• DOI för Methylation profiling reveals epigenetic programs associated with chr18 loss in small intestinal neuroendocrine tumors
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Single-Cell Comparison of Small Intestinal Neuroendocrine Tumors and Enterochromaffin Cells from Two Patients

Axling, Fredrik; Barazeghi, Elham; Hellman, Per; Norlén, Olov et al.

Ingår i Cancers, s. 435-435, 2026

• DOI för Single-Cell Comparison of Small Intestinal Neuroendocrine Tumors and Enterochromaffin Cells from Two Patients
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Metformin inhibits small intestinal neuroendocrine tumor growth in vivo

Axling, Fredrik; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Ingår i BMC Cancer, 2026

• DOI för Metformin inhibits small intestinal neuroendocrine tumor growth in vivo
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Genomic Catastrophe Defines the Evolutionary Trajectory of Adrenocortical Carcinoma

Backman, Samuel; Axling, Fredrik; Zhang, Liang; Botling, Johan et al.

Ingår i Endocrine pathology, 2026

• DOI för Genomic Catastrophe Defines the Evolutionary Trajectory of Adrenocortical Carcinoma
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Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors

Barazeghi, Elham; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Ingår i Endocrine Connections, 2025

• DOI för Loss of MBD2 is associated with tumor growth in small intestinal neuroendocrine tumors
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The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation

Backman, Samuel; Botling, Johan; Nord, Helena; Ghosal, Suman et al.

Ingår i Journal of Pathology, s. 357-370, 2024

• DOI för The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation
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PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas

Xu, Kai; Langenhuijsen, Johan F.; Vietor, Charlotte L.; Feelders, Richard A. et al.

Ingår i European Journal of Endocrinology, s. 345-353, 2024

• DOI för PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas
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Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Zhou, Junhua; Azizan, Elena A. B.; Cabrera, Claudia P.; Fernandes-Rosa, Fabio L. et al.

Ingår i Nature Genetics, s. 1360-1372, 2021

• DOI för Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma

Stenman, Adam; Backman, Samuel; Johansson, Klara; Paulsson, Johan O. et al.

Ingår i Endocrine-Related Cancer, s. 337-351, 2021

• DOI för Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma
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Whole genome sequencing of apparently mutation-negative MEN1 patients

Backman, Samuel; Bajic, Duska; Crona, Joakim; Hellman, Per et al.

Ingår i European Journal of Endocrinology, s. 35-45, 2020

• DOI för Whole genome sequencing of apparently mutation-negative MEN1 patients

Whole‐genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation

Paulsson, Johan O.; Backman, Samuel; Wang, Na; Stenman, Adam et al.

Ingår i Journal of Pathology, s. 183-194, 2020

• DOI för Whole‐genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation

RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas

Backman, Samuel; Åkerström, Tobias; Maharjan, Rajani; Cupisti, Kenko et al.

Ingår i Scientific Reports, 2019

• DOI för RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas
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Comprehensive analysis of CTNNB1 in adrenocortical carcinomas: Identification of novel mutations and correlation to survival

Maharjan, Rajani; Backman, Samuel; Åkerström, Tobias; Hellman, Per et al.

Ingår i Scientific Reports, 2018

• DOI för Comprehensive analysis of CTNNB1 in adrenocortical carcinomas: Identification of novel mutations and correlation to survival
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RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective

Crona, Joakim; Backman, Samuel; Welin, Staffan; Taieb, David et al.

Ingår i Cancers, 2018

• DOI för RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective
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Epigenetics of pheochromocytoma and paraganglioma

Björklund, Peyman; Backman, Samuel

Ingår i Molecular and Cellular Endocrinology, s. 92-97, 2018

• DOI för Epigenetics of pheochromocytoma and paraganglioma

Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations

Backman, Samuel; Maharjan, Rajani; Falk Delgado, Alberto; Crona, Joakim et al.

Ingår i Scientific Reports, 2017

• DOI för Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations
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Detection of Somatic Mutations in Gastroenteropancreatic Neuroendocrine Tumors Using Targeted Deep Sequencing

Backman, Samuel; Norlén, Olov; Eriksson, Barbro; Skogseid, Britt et al.

Ingår i Anticancer Research, s. 705-712, 2017

• DOI för Detection of Somatic Mutations in Gastroenteropancreatic Neuroendocrine Tumors Using Targeted Deep Sequencing

Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Crona, Joakim; Backman, Samuel; Maharjan, Rajani; Mayrhofer, Markus et al.

Ingår i Clinical Cancer Research, s. 4451-4460, 2015

• DOI för Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.

Åkerström, Tobias; Willenberg, Holger Sven; Cupisti, Kenko; Ip, Julian et al.

Ingår i Endocrine-Related Cancer, s. 735-744, 2015

• DOI för Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.

TFF3 in primary tumours has a negative impact on survival in small intestinal neuroendocrine tumours

Eriksson, John; Juhlin, Christofer; Backman, Samuel; Edfeldt, Katarina et al.

Molecular studies of endocrine tumors: Insights from genetics and epigenetics

Backman, Samuel

2020

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Recurrent Differentiated Carcinoma: Estimating Risk of Recurrence in Differentiated Thyroid Cancer After Total Thyroidectomy and Radioactive Iodine Remnant Ablation

Pericleous, Agamemnon; Backman, Samuel; Annebäck, Matilda; Tolley, Neil

Ingår i 50 Landmark Papers Every Thyroid and Parathyroid Surgeon Should Know, s. 127-131, CRC Press, 2023

• DOI för Recurrent Differentiated Carcinoma: Estimating Risk of Recurrence in Differentiated Thyroid Cancer After Total Thyroidectomy and Radioactive Iodine Remnant Ablation

Multiregion Analysis Reveal Evolutionary Patterns and a Chromosomal Instability Signature in Pancreatic Neuroendocrine Tumours

Crona, Joakim; Backman, Samuel; Kugelberg, Johan; Maharjan, Rajani et al.

s. 6-6, 2016

Potential prognostic markers and candidate genetic drivers in small intestine neuroendocrine tumours

Backman, Samuel; Barazeghi, Elham; Norlén, Olov; Hellman, Per et al.

Investigating resulting differential transcript usage from alternative splicing in small intestinal neuroendocrine tumors

Axling, Fredrik; Backman, Samuel; Barazeghi, Elham; Hellman, Per et al.

A single-cell comparison between small intestinal neuroendocrine tumors and their progenitor

Axling, Fredrik; Barazeghi, Elham; Hellman, Per; Norlén, Olov et al.