Samuel Backman

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Zhou, Junhua; Azizan, Elena A. B.; Cabrera, Claudia P.; Fernandes-Rosa, Fabio L. et al.

Ingår i Nature Genetics, s. 1360-1372, 2021

• DOI för Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Whole genome sequencing of apparently mutation-negative MEN1 patients

Backman, Samuel; Bajic, Duska; Crona, Joakim; Hellman, Per et al.

Ingår i European Journal of Endocrinology, s. 35-45, 2020

• DOI för Whole genome sequencing of apparently mutation-negative MEN1 patients

Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Crona, Joakim; Backman, Samuel; Maharjan, Rajani; Mayrhofer, Markus et al.

Ingår i Clinical Cancer Research, s. 4451-4460, 2015

• DOI för Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation

Backman, Samuel; Botling, Johan; Nord, Helena; Ghosal, Suman et al.

Ingår i Journal of Pathology, s. 357-370, 2024

• DOI för The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation
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PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas

Xu, Kai; Langenhuijsen, Johan F.; Vietor, Charlotte L.; Feelders, Richard A. et al.

Ingår i European Journal of Endocrinology, s. 345-353, 2024

• DOI för PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas
• Ladda ner fulltext (pdf) av PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Zhou, Junhua; Azizan, Elena A. B.; Cabrera, Claudia P.; Fernandes-Rosa, Fabio L. et al.

Ingår i Nature Genetics, s. 1360-1372, 2021

• DOI för Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma

Stenman, Adam; Backman, Samuel; Johansson, Klara; Paulsson, Johan O. et al.

Ingår i Endocrine-Related Cancer, s. 337-351, 2021

• DOI för Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma
• Ladda ner fulltext (pdf) av Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma

Molecular studies of endocrine tumors: Insights from genetics and epigenetics

Backman, Samuel

2020

• Ladda ner fulltext (pdf) av Molecular studies of endocrine tumors: Insights from genetics and epigenetics

The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation

Backman, Samuel; Botling, Johan; Nord, Helena; Ghosal, Suman et al.

Ingår i Journal of Pathology, s. 357-370, 2024

• DOI för The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation
• Ladda ner fulltext (pdf) av The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation

PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas

Xu, Kai; Langenhuijsen, Johan F.; Vietor, Charlotte L.; Feelders, Richard A. et al.

Ingår i European Journal of Endocrinology, s. 345-353, 2024

• DOI för PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas
• Ladda ner fulltext (pdf) av PRAP study-partial versus radical adrenalectomy in hereditary pheochromocytomas

Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Zhou, Junhua; Azizan, Elena A. B.; Cabrera, Claudia P.; Fernandes-Rosa, Fabio L. et al.

Ingår i Nature Genetics, s. 1360-1372, 2021

• DOI för Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause

Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma

Stenman, Adam; Backman, Samuel; Johansson, Klara; Paulsson, Johan O. et al.

Ingår i Endocrine-Related Cancer, s. 337-351, 2021

• DOI för Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma
• Ladda ner fulltext (pdf) av Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma

Whole‐genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation

Paulsson, Johan O.; Backman, Samuel; Wang, Na; Stenman, Adam et al.

Ingår i Journal of Pathology, s. 183-194, 2020

• DOI för Whole‐genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation

Whole genome sequencing of apparently mutation-negative MEN1 patients

Backman, Samuel; Bajic, Duska; Crona, Joakim; Hellman, Per et al.

Ingår i European Journal of Endocrinology, s. 35-45, 2020

• DOI för Whole genome sequencing of apparently mutation-negative MEN1 patients

RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas

Backman, Samuel; Åkerström, Tobias; Maharjan, Rajani; Cupisti, Kenko et al.

Ingår i Scientific Reports, 2019

• DOI för RNA Sequencing Provides Novel Insights into the Transcriptome of Aldosterone Producing Adenomas
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Comprehensive analysis of CTNNB1 in adrenocortical carcinomas: Identification of novel mutations and correlation to survival

Maharjan, Rajani; Backman, Samuel; Åkerström, Tobias; Hellman, Per et al.

Ingår i Scientific Reports, 2018

• DOI för Comprehensive analysis of CTNNB1 in adrenocortical carcinomas: Identification of novel mutations and correlation to survival
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RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective

Crona, Joakim; Backman, Samuel; Welin, Staffan; Taieb, David et al.

Ingår i Cancers, 2018

• DOI för RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective
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Epigenetics of pheochromocytoma and paraganglioma

Björklund, Peyman; Backman, Samuel

Ingår i Molecular and Cellular Endocrinology, s. 92-97, 2018

• DOI för Epigenetics of pheochromocytoma and paraganglioma

Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations

Backman, Samuel; Maharjan, Rajani; Falk Delgado, Alberto; Crona, Joakim et al.

Ingår i Scientific Reports, 2017

• DOI för Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations
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Detection of Somatic Mutations in Gastroenteropancreatic Neuroendocrine Tumors Using Targeted Deep Sequencing

Backman, Samuel; Norlén, Olov; Eriksson, Barbro; Skogseid, Britt et al.

Ingår i Anticancer Research, s. 705-712, 2017

• DOI för Detection of Somatic Mutations in Gastroenteropancreatic Neuroendocrine Tumors Using Targeted Deep Sequencing

Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Crona, Joakim; Backman, Samuel; Maharjan, Rajani; Mayrhofer, Markus et al.

Ingår i Clinical Cancer Research, s. 4451-4460, 2015

• DOI för Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.

Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.

Åkerström, Tobias; Willenberg, Holger Sven; Cupisti, Kenko; Ip, Julian et al.

Ingår i Endocrine-Related Cancer, s. 735-744, 2015

• DOI för Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas.

TFF3 in primary tumours has a negative impact on survival in small intestinal neuroendocrine tumours

Eriksson, John; Juhlin, Christofer; Backman, Samuel; Edfeldt, Katarina et al.

Molecular studies of endocrine tumors: Insights from genetics and epigenetics

Backman, Samuel

2020

• Ladda ner fulltext (pdf) av Molecular studies of endocrine tumors: Insights from genetics and epigenetics

Multiregion Analysis Reveal Evolutionary Patterns and a Chromosomal Instability Signature in Pancreatic Neuroendocrine Tumours

Crona, Joakim; Backman, Samuel; Kugelberg, Johan; Maharjan, Rajani et al.

s. 6-6, 2016

Potential prognostic markers and candidate genetic drivers in small intestine neuroendocrine tumours

Backman, Samuel; Barazeghi, Elham; Norlén, Olov; Hellman, Per et al.

Investigating resulting differential transcript usage from alternative splicing in small intestinal neuroendocrine tumors

Axling, Fredrik; Backman, Samuel; Barazeghi, Elham; Hellman, Per et al.

Long-read whole-genome sequencing reveals genomic and epigenomic features of small intestinal neuroendocrine tumors

Axling, Fredrik; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

Metformin inhibits small intestinal neuroendocrine tumor growth in vivo

Axling, Fredrik; Backman, Samuel; Hellman, Per; Norlén, Olov et al.

A single-cell comparison between small intestinal neuroendocrine tumors and their progenitor

Axling, Fredrik; Barazeghi, Elham; Hellman, Per; Norlén, Olov et al.