Ximena Aguilar

PET imaging of TREM2 in amyloid-beta induced neuroinflammation

Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena; Bucher, Nadja et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4320-4333, 2025

• DOI för PET imaging of TREM2 in amyloid-beta induced neuroinflammation
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Updated transient gene expression protocol in Expi293F cells using PEI

Hederoth, Gustaf; de la Rosa, Andrés; Godec, Ana; Aguilar, Ximena et al.

Ingår i Frontiers in Bioengineering and Biotechnology, 2025

• DOI för Updated transient gene expression protocol in Expi293F cells using PEI
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Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease

Sehlin, Dag; Hultqvist, Greta; Michno, Wojciech; Aguilar, Ximena et al.

Ingår i The Journal of Prevention of Alzheimer's Disease, 2025

• DOI för Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease
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Brain-penetrating peptide and antibody radioligands for proof-of-concept PET imaging of fibrin in Alzheimer's disease

Sehlin, Dag; Aguilar, Ximena; Cortes-Canteli, Marta; Syvänen, Stina et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Brain-penetrating peptide and antibody radioligands for proof-of-concept PET imaging of fibrin in Alzheimer's disease
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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PET imaging of TREM2 in amyloid-beta induced neuroinflammation

Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena; Bucher, Nadja et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, s. 4320-4333, 2025

• DOI för PET imaging of TREM2 in amyloid-beta induced neuroinflammation
• Ladda ner fulltext (pdf) av PET imaging of TREM2 in amyloid-beta induced neuroinflammation

Updated transient gene expression protocol in Expi293F cells using PEI

Hederoth, Gustaf; de la Rosa, Andrés; Godec, Ana; Aguilar, Ximena et al.

Ingår i Frontiers in Bioengineering and Biotechnology, 2025

• DOI för Updated transient gene expression protocol in Expi293F cells using PEI
• Ladda ner fulltext (pdf) av Updated transient gene expression protocol in Expi293F cells using PEI

Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease

Sehlin, Dag; Hultqvist, Greta; Michno, Wojciech; Aguilar, Ximena et al.

Ingår i The Journal of Prevention of Alzheimer's Disease, 2025

• DOI för Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease
• Ladda ner fulltext (pdf) av Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease

Brain-penetrating peptide and antibody radioligands for proof-of-concept PET imaging of fibrin in Alzheimer's disease

Sehlin, Dag; Aguilar, Ximena; Cortes-Canteli, Marta; Syvänen, Stina et al.

Ingår i EJNMMI Radiopharmacy and Chemistry, 2025

• DOI för Brain-penetrating peptide and antibody radioligands for proof-of-concept PET imaging of fibrin in Alzheimer's disease
• Ladda ner fulltext (pdf) av Brain-penetrating peptide and antibody radioligands for proof-of-concept PET imaging of fibrin in Alzheimer's disease

Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
• Ladda ner fulltext (pdf) av Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion

Pagnon de la Vega, María; Syvänen, Stina; Giedraitis, Vilmantas; Hooley, Monique et al.

Ingår i Acta neuropathologica communications, 2024

• DOI för Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion
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CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation

Konstantinidis, Evangelos; Molisak, Agnieszka; Perrin, Florian; Streubel-Gallasch, Linn et al.

Ingår i Molecular Therapy Nucleic Acids, s. 450-461, 2022

• DOI för CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN1 M146L mutation
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Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size

Faresjö, Rebecca; Bonvicini, Gillian; Fang, Xiaotian T.; Aguilar, Ximena et al.

Ingår i Fluids and Barriers of the CNS, 2021

• DOI för Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size
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Long-Term Effects of Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease

Zysk, Marlena; Clausen, Fredrik; Aguilar, Ximena; Sehlin, Dag et al.

Ingår i Journal of Alzheimer's Disease, s. 161-180, 2019

• DOI för Long-Term Effects of Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease
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Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

Olsen, Malin; Aguilar, Ximena; Sehlin, Dag; Fang, Xiaotian T. et al.

Ingår i Molecular Imaging and Biology, s. 605-614, 2018

• DOI för Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease
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PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Ingår i Pharmaceutical research, s. 1481-1496, 2022

• DOI för PET Imaging in Preclinical Anti-Aβ Drug Development
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Over the BBB and into the cell: Pursuing intracellular targets for immunotherapy of Parkinson’s disease

Stenler, Sofia; Roshanbin, Sahar; Yilmaz Ugur, Canan; Rostami, Jinar et al.

2019

Transgenic mice harboring the Uppsala APP mutation display altered APP processing and accelerated Aβ42 pathology with distinct structural features

Pagnon de la Vega, María; Syvänen, Stina; Hooley, Monique; Giedraitis, Vilmantas et al.

CRISPR/Cas9 as a tool to disrupt wild-type and A53T SNCA in sporadic and familial Parkinson’s disease

Molisak, Agnieszka; Konstantinidis, Evangelos; Aguilar, Ximena; Giedraitis, Vilmantas et al.

[¹¹C]PiB binding after treatment with an amyloid-beta antibody

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena et al.