Martin Lord

Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

Fletcher, Erika A. K.; Cordfunke, Robert A.; Nasi, Aikaterini; Törnqvist, Gunilla et al.

Ingår i Molecular Therapy: Oncology, 2025

• DOI för Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement
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A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Mebrahtu, Aman; Laurén, Ida; Veerman, Rosanne; Güclüler Akpinar, Gözde et al.

Ingår i Nature Communications, 2024

• DOI för A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice
• Ladda ner fulltext (pdf) av A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma

Abdelrazak Morsy, Mohammad Hamdy; Lilienthal, Ingrid; Lord, Martin; Merrien, Magali et al.

Ingår i Blood, s. 1953-1964, 2024

• DOI för SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma

Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Kerzeli, Iliana Kyriaki; Kostakis, Alexandros; Türker, Polat; Malmström, Per-Uno et al.

Ingår i BMC Cancer, 2023

• DOI för Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer
• Ladda ner fulltext (pdf) av Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies

Eriksson, Camilla; Gunasekera, Sunithi; Muhammad, Taj; Zhang, Mingshu et al.

Ingår i ChemBioChem, 2023

• DOI för Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies
• Ladda ner fulltext (pdf) av Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies

Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

Fletcher, Erika A. K.; Cordfunke, Robert A.; Nasi, Aikaterini; Törnqvist, Gunilla et al.

Ingår i Molecular Therapy: Oncology, 2025

• DOI för Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement
• Ladda ner fulltext (pdf) av Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Mebrahtu, Aman; Laurén, Ida; Veerman, Rosanne; Güclüler Akpinar, Gözde et al.

Ingår i Nature Communications, 2024

• DOI för A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice
• Ladda ner fulltext (pdf) av A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma

Abdelrazak Morsy, Mohammad Hamdy; Lilienthal, Ingrid; Lord, Martin; Merrien, Magali et al.

Ingår i Blood, s. 1953-1964, 2024

• DOI för SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma

Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Kerzeli, Iliana Kyriaki; Kostakis, Alexandros; Türker, Polat; Malmström, Per-Uno et al.

Ingår i BMC Cancer, 2023

• DOI för Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer
• Ladda ner fulltext (pdf) av Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies

Eriksson, Camilla; Gunasekera, Sunithi; Muhammad, Taj; Zhang, Mingshu et al.

Ingår i ChemBioChem, 2023

• DOI för Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies
• Ladda ner fulltext (pdf) av Epitopes displayed in a cyclic peptide scaffold bind SARS-CoV-2 antibodies

An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies

Eltahir, Mohamed; Lauren, Ida; Lord, Martin; Chourlia, Aikaterini et al.

Ingår i Advanced Therapeutics, 2022

• DOI för An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies
• Ladda ner fulltext (pdf) av An Adaptable Antibody-Based Platform for Flexible Synthetic Peptide Delivery Built on Agonistic CD40 Antibodies

Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology

Lauren, Ida; Havervall, Sebastian; Ng, Henry; Lord, Martin et al.

Ingår i Immunity, Inflammation and Disease, 2022

• DOI för Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology
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Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19

Havervall, Sebastian; Ng, Henry; Jernbom Falk, August; Greilert-Norin, Nina et al.

Ingår i Journal of Internal Medicine, s. 72-80, 2022

• DOI för Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19
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Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells

Napoleone, Antonino; Laurén, Ida; Linkgreim, Triinu; Dahllund, Leif et al.

Ingår i New Biotechnology, s. 9-19, 2021

• DOI för Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells
• Ladda ner fulltext (pdf) av Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells

Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

Kerzeli, Iliana Kyriaki; Lord, Martin; Doroszko, Milena; Elgendy, Ramy et al.

Ingår i PLOS ONE, 2021

• DOI för Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
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An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses

Mangsbo, Sara; Havervall, Sebastian; Laurén, Ida; Lindsay, Robin et al.

Ingår i PLOS ONE, 2021

• DOI för An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses
• Ladda ner fulltext (pdf) av An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses

Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Eltahir, Mohamed; Isaksson, Johan; Mattsson, Johanna Sofia Margareta; Karre, Klas et al.

Ingår i Cancers, 2021

• DOI för Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade
• Ladda ner fulltext (pdf) av Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients

Eltahir, mohmo394; Fletcher, E.; Dynesius, L.; Jarblad, J. L. et al.

Ingår i International Immunopharmacology, 2021

• DOI för Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients
• Ladda ner fulltext (pdf) av Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients

Plasma proteomic analysis in non-small cell lung cancer patients treated with PD1/PD-L1 blockade

Eltahir, Mohamed; Isaksson, Johan; Mattsson, Johanna Sofia Margareta; Kärre, Klas et al.

The tumour microenvironment across tumour evolution in bladder cancer profiled by single-cell RNA-sequencing analysis and spatial transcriptomics

Kostakis, Alexandros; Beháňová, Andrea; Kyriaki Kerzeli, Iliana; Elgendy, Ramy et al.

Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange

Laurén, Ida; Kostakis, Alexandros; Lord, Martin; Björklund, Elvira et al.