Mengfei Xiong

Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis

Wik, Elin; Dahlén, Amelia; Julku, Ulrika; Xiong, Mengfei et al.

Ingår i Neurotherapeutics, 2026

• DOI för Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis
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Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors

Khalil, Amina; Velikyan, Irina; Xiong, Mengfei; Bossart, Martin et al.

Ingår i eBioMedicine, 2025

• DOI för Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors
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Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity

Bonvicini, Gillian; Singh, Sunitha; Nygren, Patrik; Xiong, Mengfei et al.

Ingår i Analytical Biochemistry, 2024

• DOI för Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Evaluation of [¹¹C]UCB-A positron emission tomography in human brains

Xiong, Mengfei; Lubberink, Mark; Appel, Lieuwe; Fang, Xiaotian Tsong et al.

Ingår i EJNMMI Research, 2024

• DOI för Evaluation of [¹¹C]UCB-A positron emission tomography in human brains
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Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis

Wik, Elin; Dahlén, Amelia; Julku, Ulrika; Xiong, Mengfei et al.

Ingår i Neurotherapeutics, 2026

• DOI för Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis
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Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors

Khalil, Amina; Velikyan, Irina; Xiong, Mengfei; Bossart, Martin et al.

Ingår i eBioMedicine, 2025

• DOI för Positron emission tomography to assess drug occupancy at peripheral and central incretin receptors
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Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity

Bonvicini, Gillian; Singh, Sunitha; Nygren, Patrik; Xiong, Mengfei et al.

Ingår i Analytical Biochemistry, 2024

• DOI för Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity
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Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin et al.

Ingår i Journal of Neurochemistry, s. 2601-2610, 2024

• DOI för Antibody engagement with amyloid‐beta does not inhibit [¹¹C]PiB binding for PET imaging
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Evaluation of [¹¹C]UCB-A positron emission tomography in human brains

Xiong, Mengfei; Lubberink, Mark; Appel, Lieuwe; Fang, Xiaotian Tsong et al.

Ingår i EJNMMI Research, 2024

• DOI för Evaluation of [¹¹C]UCB-A positron emission tomography in human brains
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Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

Ingår i NeuroImage, 2023

• DOI för Synaptic density in aging mice measured by [18F]SynVesT-1 PET
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Brain pharmacokinetics of mono- and bispecific amyloid-beta antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis

Julku, Ulrika; Xiong, Mengfei; Wik, Elin; Roshanbin, Sahar et al.

Ingår i Fluids and Barriers of the CNS, 2022

• DOI för Brain pharmacokinetics of mono- and bispecific amyloid-beta antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis
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Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody

Roshanbin, Sahar; Julku, Ulrika; Xiong, Mengfei; Eriksson, Jonas et al.

Ingår i Pharmaceutics, 2022

• DOI för Reduction of alpha SYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody
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In vivo imaging of alpha-synuclein with antibody-based PET

Roshanbin, Sahar; Xiong, Mengfei; Hultqvist, Greta; Soderberg, Linda et al.

Ingår i Neuropharmacology, 2022

• DOI för In vivo imaging of alpha-synuclein with antibody-based PET
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In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease

Xiong, Mengfei; Roshanbin, Sahar; Rokka, Johanna; Schlein, Eva et al.

Ingår i NeuroImage, 2021

• DOI för In vivo imaging of synaptic density with [C-11]UCB-J PET in two mouse models of neurodegenerative disease
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Blocking of efflux transporters in rats improves translational validation of brain radioligands

Shalgunov, Vladimir; Xiong, Mengfei; L'Estrade, Elina T.; Raval, Nakul R. et al.

Ingår i EJNMMI Research, 2020

• DOI för Blocking of efflux transporters in rats improves translational validation of brain radioligands
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PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Ingår i Pharmaceutical research, s. 1481-1496, 2022

• DOI för PET Imaging in Preclinical Anti-Aβ Drug Development
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Visualising neurodegeneration in the living brain: Preclinical evaluation of PET radioligands

Xiong, Mengfei

2023

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Synaptic density in aging mice measured by [¹⁸F]SynVesT-1 PET

Xiong, Mengfei; Roshanbin, Sahar; Sehlin, Dag; Hansen, Hanne D. et al.

[¹¹C]PiB binding after treatment with an amyloid-beta antibody

Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Aguilar, Ximena et al.