Gillian Bonvicini

High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

Bonvicini, Gillian; Singh, Sunitha; Sandersjöö, Lisa; Dallas, Tiffany et al.

Ingår i Fluids and Barriers of the CNS, 2025

• DOI för High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose
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The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo

Bonvicini, Gillian; Singh, Sunitha; Sandersjoo, Lisa; Sehlin, Dag et al.

Ingår i Fluids and Barriers of the CNS, 2025

• DOI för The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo
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Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity

Bonvicini, Gillian; Singh, Sunitha; Nygren, Patrik; Xiong, Mengfei et al.

Ingår i Analytical Biochemistry, 2024

• DOI för Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity
• Ladda ner fulltext (pdf) av Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity

Harnessing the molecular Trojan horse: Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor

Bonvicini, Gillian

2023

• Ladda ner fulltext (pdf) av Harnessing the molecular Trojan horse: Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor

PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Ingår i Pharmaceutical research, s. 1481-1496, 2022

• DOI för PET Imaging in Preclinical Anti-Aβ Drug Development
• Ladda ner fulltext (pdf) av PET Imaging in Preclinical Anti-Aβ Drug Development

High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

Bonvicini, Gillian; Singh, Sunitha; Sandersjöö, Lisa; Dallas, Tiffany et al.

Ingår i Fluids and Barriers of the CNS, 2025

• DOI för High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose
• Ladda ner fulltext (pdf) av High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo

Bonvicini, Gillian; Singh, Sunitha; Sandersjoo, Lisa; Sehlin, Dag et al.

Ingår i Fluids and Barriers of the CNS, 2025

• DOI för The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo
• Ladda ner fulltext (pdf) av The effects of dose, valency, and affinity on TfR-mediated brain delivery in vivo

Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity

Bonvicini, Gillian; Singh, Sunitha; Nygren, Patrik; Xiong, Mengfei et al.

Ingår i Analytical Biochemistry, 2024

• DOI för Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity
• Ladda ner fulltext (pdf) av Comparing in vitro affinity measurements of antibodies to TfR1: Surface plasmon resonance versus on-cell affinity

ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein

Bonvicini, Gillian; Syvänen, Stina; Andersson, Ken G. G.; Haaparanta-Solin, Merja et al.

Ingår i Translational Neurodegeneration, 2022

• DOI för ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein
• Ladda ner fulltext (pdf) av ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein

Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size

Faresjö, Rebecca; Bonvicini, Gillian; Fang, Xiaotian T.; Aguilar, Ximena et al.

Ingår i Fluids and Barriers of the CNS, 2021

• DOI för Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size
• Ladda ner fulltext (pdf) av Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size

PET Imaging in Preclinical Anti-Aβ Drug Development

Syvänen, Stina; Meier, Silvio R.; Roshanbin, Sahar; Xiong, Mengfei et al.

Ingår i Pharmaceutical research, s. 1481-1496, 2022

• DOI för PET Imaging in Preclinical Anti-Aβ Drug Development
• Ladda ner fulltext (pdf) av PET Imaging in Preclinical Anti-Aβ Drug Development

Harnessing the molecular Trojan horse: Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor

Bonvicini, Gillian

2023

• Ladda ner fulltext (pdf) av Harnessing the molecular Trojan horse: Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor

Stronger affinity to Transferrin receptor enhances detection of amyloid-β pathology with bispecific antibody radioligands at a tracer dose

Bonvicini, Gillian; Singh, Sunitha; Sandersjöö, Lisa; Dallas, Tiffany et al.

Evaluation of valency effects on TfR-mediated brain delivery in vivo

Bonvicini, Gillian; Singh, Sunitha; Sandersjöö, Lisa; Sehlin, Dag et al.