Abdulkhalek Dakhel

Characterization of a distinct form of vimentin in the neurodegenerative brain

Dakhel, Abdulkhalek; Vestin, Johanna; Giedraitis, Vilmantas; Nyholm, Dag et al.

Ingår i Acta neuropathologica communications, 2026

• DOI för Characterization of a distinct form of vimentin in the neurodegenerative brain
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Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids

Dakhel, Abdulkhalek; Mothes, Tobias; Eltom, Khalid; Michno, Wojciech et al.

Ingår i iScience, 2026

• DOI för Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids
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What they do in the shadows: Uncovering hidden roles of astrocytes in the neurodegenerative brain

Dakhel, Abdulkhalek

2026

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Zombosomes are anucleated cell couriers that spread α-synuclein pathology

Dakhel, Abdulkhalek; Beretta, Chiara; Mothes, Tobias; Hakhverdyan, Sona et al.

Ingår i Cell Reports, 2026

• DOI för Zombosomes are anucleated cell couriers that spread α-synuclein pathology
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Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery

Beretta, Chiara; Dakhel, Abdulkhalek; Eltom, Khalid; Rosqvist, Fredrik et al.

Ingår i Journal of Neuroinflammation, 2025

• DOI för Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
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Characterization of a distinct form of vimentin in the neurodegenerative brain

Dakhel, Abdulkhalek; Vestin, Johanna; Giedraitis, Vilmantas; Nyholm, Dag et al.

Ingår i Acta neuropathologica communications, 2026

• DOI för Characterization of a distinct form of vimentin in the neurodegenerative brain
• Ladda ner fulltext (pdf) av Characterization of a distinct form of vimentin in the neurodegenerative brain

Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids

Dakhel, Abdulkhalek; Mothes, Tobias; Eltom, Khalid; Michno, Wojciech et al.

Ingår i iScience, 2026

• DOI för Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids
• Ladda ner fulltext (pdf) av Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids

Zombosomes are anucleated cell couriers that spread α-synuclein pathology

Dakhel, Abdulkhalek; Beretta, Chiara; Mothes, Tobias; Hakhverdyan, Sona et al.

Ingår i Cell Reports, 2026

• DOI för Zombosomes are anucleated cell couriers that spread α-synuclein pathology
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Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery

Beretta, Chiara; Dakhel, Abdulkhalek; Eltom, Khalid; Rosqvist, Fredrik et al.

Ingår i Journal of Neuroinflammation, 2025

• DOI för Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
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Tau processing and tau-mediated inflammation differ in human APOEε2 and APOEε4 astrocytes

Mothes, Tobias; Konstantinidis, Evangelos; Eltom, Khalid; Dakhel, Abdulkhalek et al.

Ingår i iScience, 2024

• DOI för Tau processing and tau-mediated inflammation differ in human APOEε2 and APOEε4 astrocytes
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Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms

Beretta, Chiara; Svensson, Elina; Dakhel, Abdulkhalek; Zyśk, Marlena et al.

Ingår i Molecular and Cellular Neuroscience, 2024

• DOI för Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms
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Amyloid-beta accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

Zyśk, Marlena; Beretta, Chiara; Naia, Luana; Dakhel, Abdulkhalek et al.

Ingår i Journal of Neuroinflammation, 2023

• DOI för Amyloid-beta accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism
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Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes

Konstantinidis, Evangelos; Dakhel, Abdulkhalek; Beretta, Chiara; Erlandsson, Anna

Ingår i Molecular and Cellular Neuroscience, 2023

• DOI för Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes
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What they do in the shadows: Uncovering hidden roles of astrocytes in the neurodegenerative brain

Dakhel, Abdulkhalek

2026

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Astrocytes with Alzheimer’s disease pathology provoke lipid droplet mediated cell-to-cell propagation of MHC II complexes

Beretta, Chiara; Dakhel, Abdulkhalek; Eltom, Khalid; Rosqvist, Fredrik et al.