Axel Leppert

Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers

Tufvesson, Karin; Langwallner, Viktoria; Pessatti, Tomas Bohn; Greco, Gabriele et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI för Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers
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Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Dirks, Christopher; Schlotterbeck, Ann-Kathrin; Pettersson, Pontus; Leppert, Axel et al.

Ingår i Journal of Biological Chemistry, 2026

• DOI för Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity
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Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Bohn Pessatti, Tomas; Schmuck, Benjamin; Greco, Gabriele; Stadlmayr, Sarah et al.

Ingår i Communications Materials, 2026

• DOI för Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins
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Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Osterholz, Hannah; Jeyalekshmy, Shree Senthil; Schmuck, Benjamin; Bohn Pessatti, Tomas et al.

Ingår i Communications Materials, 2026

• DOI för Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly
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Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Morman, Cecilia; Leppert, Axel; Pizzirusso, Giusy; Zheng, Zihan et al.

Ingår i Journal of the American Chemical Society, s. 23504-23518, 2025

• DOI för Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity
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Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers

Tufvesson, Karin; Langwallner, Viktoria; Pessatti, Tomas Bohn; Greco, Gabriele et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI för Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers
• Ladda ner fulltext (pdf) av Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers

Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Dirks, Christopher; Schlotterbeck, Ann-Kathrin; Pettersson, Pontus; Leppert, Axel et al.

Ingår i Journal of Biological Chemistry, 2026

• DOI för Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity
• Ladda ner fulltext (pdf) av Allosteric targeting with antiviral nucleotide analogs allows fine-tuning of SAMHD1 dNTPase activity

Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Bohn Pessatti, Tomas; Schmuck, Benjamin; Greco, Gabriele; Stadlmayr, Sarah et al.

Ingår i Communications Materials, 2026

• DOI för Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins
• Ladda ner fulltext (pdf) av Intrinsically colored artificial silk fibers made from mini-spidroin fusion proteins

Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Osterholz, Hannah; Jeyalekshmy, Shree Senthil; Schmuck, Benjamin; Bohn Pessatti, Tomas et al.

Ingår i Communications Materials, 2026

• DOI för Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly
• Ladda ner fulltext (pdf) av Single-molecule mass measurements reveal distinct effects of sodium and potassium on mini-spidroin assembly

Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Morman, Cecilia; Leppert, Axel; Pizzirusso, Giusy; Zheng, Zihan et al.

Ingår i Journal of the American Chemical Society, s. 23504-23518, 2025

• DOI för Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity
• Ladda ner fulltext (pdf) av Chaperone-Mediated Regulation of Tau Phase Separation, Fibrillation, and Toxicity

Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor

Jin, Zhen; Pallisgaard Olsen, William; Mörman, Cecilia; Leppert, Axel et al.

Ingår i Science Advances, 2025

• DOI för Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor
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Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Ingår i JACS Au, s. 281-290, 2025

• DOI för Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
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Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions

Leppert, Axel; Feng, Jianhui; Railaite, Vaida; Pessatti, Tomas Bohn et al.

Ingår i Journal of the American Chemical Society, s. 19555-19565, 2024

• DOI för Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions
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Liquid-liquid crystalline phase separation of spider silk proteins

Landreh, Michael; Osterholz, Hannah; Chen, Gefei; Knight, Stefan D. et al.

Ingår i Communications Chemistry, 2024

• DOI för Liquid-liquid crystalline phase separation of spider silk proteins
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