Miklós Lipcsey

Publikationer

Senaste publikationer

• Different distances between central venous catheter tips can affect antibiotic clearance during continuous renal replacement therapy (2024)
• Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients (2024)
• Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure (2024)
• Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity (2024)
• Surviving COVID-19 (2024)

Alla publikationer

Artiklar

• Different distances between central venous catheter tips can affect antibiotic clearance during continuous renal replacement therapy (2024)
• Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients (2024)
• Body mass index is associated with pulmonary gas and blood distribution mismatch in COVID-19 acute respiratory failure (2024)
• Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity (2024)
• Surviving COVID-19 (2024)
• Uromodulin in sepsis and severe pneumonia (2024)
• Influenza-associated invasive aspergillosis in patients admitted to the intensive care unit in Sweden (2024)
• Protocolized reduction of non-resuscitation fluids versus usual care in septic shock patients (REDUSE) (2024)
• A nationwide cohort study on the association between intensive care treatments and mental distress linked psychiatric disorders (2024)
• Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer-Insights from Histologically Normal Urothelium (2024)
• Smoking is associated with higher risk of contracting bacterial infection and pneumonia, intensive care unit admission and death (2024)
• Physical activity is associated with a lower risk of contracting and dying in infection and sepsis (2024)
• Plasma Biomarkers Associated to Outcome in Patients with Sars-Cov-2 Infection (2024)
• Returning to work and health status at 12 months among patients with COVID-19 cared for in intensive care (2024)
• The Human Phospholipase B-II Precursor (HPLBII-P) in Urine as a Novel Biomarker of Glomerular Activity in COVID-19 and Diabetes Mellitus (2024)
• In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients (2023)
• Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19 (2023)
• Predicting cytokine kinetics during sepsis; a modelling framework from a porcine sepsis model with live Escherichia coli (2023)
• In an endotoxaemic model, antibiotic clearance can be affected by different central venous catheter positions, during renal replacement therapy (2023)
• Central nervous system biomarkers GFAp and NfL associate with post-acute cognitive impairment and fatigue following critical COVID-19 (2023)
• Acetaminophen Attenuates Pulmonary Vascular Resistance and Pulmonary Arterial Pressure and Inhibits Cardiovascular Collapse in a Porcine Model of Endotoxemia (2023)
• Health-related quality of life after surviving intensive care for COVID-19 (2023)
• Analysis of Calprotectin as an Early Marker of Infections Is Economically Advantageous in Intensive Care-Treated Patients (2023)
• Risk of malignant disease in 1-year sepsis survivors, a registry-based nationwide follow-up study (2023)
• Point of Care Analysis of Hematology in the Operating Theater - a Prospective Observational Study of Accuracy and Feasibility (2023)
• Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria (2023)
• An experimental porcine model of invasive candidiasis (2023)
• Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019 (2023)
• Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up (2023)
• Protocolised reduction of non-resuscitation fluids versus usual care in patients with septic shock (REDUSE) (2023)
• Infectious SARS-CoV-2 is rarely present in the nasopharynx samples collected from Swedish hospitalized critically ill COVID-19 patients (2023)
• The Use of Diffusion Weighted Imaging and Intravoxel Incoherent Motion to Assess Edema and Perfusion in Abdominal Organs during Endotoxemia (2023)
• The burden of critical illness among adults in a Swedish region-a population-based point-prevalence study (2023)
• Swedish multicentre study of target attainments with β-lactams in the ICU (2023)
• Strain on the ICU resources and patient outcomes in the COVID-19 pandemic (2023)
• Prior physical illness predicts death better than acute physiological derangement on intensive care unit admission in COVID-19 (2023)
• Design of a national patient-centred clinical pathway for sepsis in Sweden (2023)
• Association of socioeconomic and demographic factors with limitations of life sustaining treatment in the intensive care unit (2023)
• Therapeutic drug monitoring of vancomycin and meropenem (2023)
• Early decreased respiratory chain capacity in resuscitated experimental sepsis is a major contributor to lactate production (2023)
• Enhanced bacterial clearance in early secondary sepsis in a porcine intensive care model. (2023)
• A second update on mapping the human genetic architecture of COVID-19 (2023)
• A comparison of impact of comorbidities and demographics on 60-day mortality in ICU patients with COVID-19, sepsis and acute respiratory distress syndrome (2022)
• Optimized diagnosis-based comorbidity measures for all-cause mortality prediction in a national population-based ICU population (2022)
• Delayed, Unprovoked, Hemodynamic Collapse with Following Asystole in a Pediatric Patient Following a High-Voltage Injury (2022)
• The Evolution of Blood Cell Phenotypes, Intracellular and Plasma Cytokines and Morphological Changes in Critically Ill COVID-19 Patients (2022)
• Loss of Y in leukocytes as a risk factor for critical COVID-19 in men (2022)
• Exome-wide association study to identify rare variants influencing COVID-19 outcomes (2022)
• Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity (2022)
• The extent of neuroradiological findings in COVID-19 shows correlation with blood biomarkers, Glasgow coma scale score and days in intensive care (2022)
• Addition of cystatin C predicts cardiovascular death better than creatinine in intensive care. (2022)
• Cutaneous steam burns and steam inhalation injuries (2022)
• Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19 (2022)
• Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation (2022)
• Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation (2022)
• Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19 (2022)
• Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients. (2022)
• Differential Bias for Creatinine- and Cystatin C- Derived Estimated Glomerular Filtration Rate in Critical COVID-19. (2022)
• Plasma Leptin Is Increased in Intensive Care Patients with COVID-19—An Investigation Performed in the PronMed-Cohort (2022)
• Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19 (2022)
• Urine Hydrogen Peroxide Levels and Their Relation to Outcome in Patients with Sepsis, Septic Shock, and Major Burn Injury (2022)
• Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging (2022)
• Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model. (2022)
• Suction cup on a piston-based chest compression device improves coronary perfusion pressure and cerebral oxygenation during experimental cardiopulmonary resuscitation (2022)
• How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment (2022)
• Intravenous anti-P. aeruginosa IgY-antibodies do not decrease pulmonary bacterial concentrations in a porcine model of ventilator-associated pneumonia (2022)
• A first update on mapping the human genetic architecture of COVID-19 (2022)
• Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients (2022)
• Göran Hedenstierna (1941-2021) (2022)
• Low attainment to PK/PD-targets for β-lactams in a multi-center study on the first 72 h of treatment in ICU patients (2022)
• Population pharmacokinetics of cefotaxime in intensive care patients (2022)
• Intensive care-treated COVID-19 patients' perception of their illness and remaining symptoms. (2022)
• Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021 (2022)
• A global systematic analysis of the occurrence, severity, and recovery pattern of long COVID in 2020 and 2021 (2022)
• The swedish covid-19 intensive care cohort (2021)
• Vasopressor Responsiveness Beyond Arterial Pressure (2021)
• Plasma endostatin correlates with hypoxia and mortality in COVID-19-associated acute respiratory failure (2021)
• Prevalence and impact of chronic dysglycemia in intensive care unit patients-A retrospective cohort study. (2021)
• Systemic Human Neutrophil Lipocalin Associates with Severe Acute Kidney Injury in SARS-CoV-2 Pneumonia (2021)
• Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients (2021)
• COVID-19 Antibody Testing of Patients Admitted to the ICU by A Novel, Point-of-Care Assay, and the Relationship to Survival (2021)
• Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge (2021)
• Bestämning av kalprotektin av värde vid diagnostik av svår infektion (2021)
• Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients (2021)
• Point of care ultrasound screening for deep vein thrombosis in critically ill COVID-19 patients, an observational study (2021)
• Urinary cytokines correlate with acute kidney injury in critically ill COVID-19 patients (2021)
• Glycemic lability index and mortality in critically ill patients-A multicenter cohort study (2021)
• Cystatin C predicts long term mortality better than creatinine in a nationwide study of intensive care patients (2021)
• Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients (2021)
• Histone H3 Cleavage in Severe COVID-19 ICU Patients. (2021)
• Elevated Angiopoietin-2 inhibits thrombomodulin-mediated anticoagulation in critically ill COVID-19 patients (2021)
• Severe acute kidney injury associated with progression of chronic kidney disease after critical COVID-19 (2021)
• The impact of viremia on organ failure, biomarkers and mortality in a Swedish cohort of critically ill COVID-19 patients (2021)
• High expression of neutrophil and monocyte CD64 with simultaneous lack of upregulation of adhesion receptors CD11b, CD162, CD15, CD65 on neutrophils in severe COVID-19 (2021)
• Effects of extensive bleeding in pigs on laboratory biomarkers (2021)
• The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System (2021)
• COVID-19 patients in intensive care develop predominantly oliguric acute kidney injury (2021)
• The contribution of plasma urea to total osmolality during iatrogenic fluid reduction in critically ill patients (2021)
• Hidden sources of fluids, sodium and potassium in stabilised Swedish ICU patients (2021)
• Lung-protective ventilation increases cerebral metabolism and non-inflammatory brain injury in porcine experimental sepsis (2021)
• Bronchially instilled IgY-antibodies did not decrease pulmonary p. aeruginosa concentration in experimental porcine pneumonia (2021)
• A quantitative analysis of extension and distribution of lung injury in COVID-19 (2021)
• ECG pathology and its association with death in critically ill COVID-19 patients, a cohort study (2021)
• A Comparison between Endostatin and Conventional Biomarkers on 30-Day Mortality and Renal Replacement Therapy in Unselected Intensive Care Patients (2021)
• Soluble TNF receptors predict acute kidney injury and mortality in critically ill COVID-19 patients (2021)
• A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity (2021)
• Mapping the human genetic architecture of COVID-19 (2021)
• A nationwide study of the long-term prevalence of dementia and its risk factors in the Swedish intensive care cohort (2020)
• Neutrophil Gelatinase-Associated Lipocalin Measured on Clinical Laboratory Platforms for the Prediction of Acute Kidney Injury and the Associated Need for Dialysis Therapy (2020)
• Weak anti-SARS-CoV-2 antibody response is associated with mortality in a Swedish cohort of COVID-19 patients in critical care (2020)
• TNFR1, TNFR2, neutrophil gelatinase-associated lipocalin and heparin binding protein in identifying sepsis and predicting outcome in an intensive care cohort (2020)
• Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients (2020)
• Presence of SARS-CoV-2 in urine is rare and not associated with acute kidney injury in critically ill COVID-19 patients (2020)
• Blood type A associates with critical COVID-19 and death in a Swedish cohort (2020)
• Evaluation of Automated Determination of Bilirubin and Oxyhemoglobin in Cerebrospinal Fluid Using the DrugLog© Instrument (2020)
• Calprotectin is superior to procalcitonin as a sepsis marker and predictor of 30-day mortality in intensive care patients (2020)
• Endotoxin removal in septic shock with the Alteco LPS adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial-the asset study (2020)
• Effect of mechanical ventilation versus spontaneous breathing on abdominal edema and inflammation in ARDS (2020)
• Lung-protective ventilation suppresses systemic and hepatic vein levels of cell-free DNA in porcine experimental post-operative sepsis (2020)
• Mode of Bacterial Killing Affects the Inflammatory Response and Associated Organ Dysfunctions in a Porcine E. coli Intensive Care Sepsis Model (2020)
• Pre-exposure to mechanical ventilation and endotoxemia increases Pseudomonas aeruginosa growth in lung tissue during experimental porcine pneumonia (2020)
• Inadequate prophylactic effect of low-molecular weight heparin in critically ill COVID-19 patients (2020)
• Mortality after Severe Sepsis and Septic Shock in Swedish Intensive Care Units 2008-2016 (2020)
• The time-course of the inflammatory response to major burn injury and its relation to organ failure and outcome (2019)
• The effect of hemorrhagic shock and intraosseous adrenaline injection on the delivery of a subsequently administered drug - an experimental study (2019)
• Central Venous Line and Dialysis Catheter Position Affects Drug Clearance during Continuous Renal Replacement Therapy in an Animal Model. (2019)
• The impact of the systemic inflammatory response on hepatic bacterial elimination in experimental abdominal sepsis (2019)
• Rapid testing of red blood cell parameters in primary care patients using HemoScreen™ point of care instrument (2019)
• Rapid testing of red blood cells, white blood cells and platelets in intensive care patients using the HemoScreen™ point-of-care analyzer (2019)
• Multivariable models using administrative data and biomarkers to adjust for case mix in the ICU (2019)
• The time course of calprotectin liberation from human neutrophil granulocytes after Escherichia coli and endotoxin challenge (2019)
• Abdominal organ perfusion and inflammation in experimental sepsis (2019)
• Inhalation of specific anti-Pseudomonas aeruginosa IgY antibodies transiently decreases P. aeruginosa colonization of the airway in mechanically ventilated piglets (2019)
• Comparison of Intraosseous, Arterial, and Venous Blood Sampling for Laboratory Analysis in Hemorrhagic Shock (2019)
• A non-linear mixed effect model for innate immune response (2019)
• Nu gäller Sepsis-3 för definitioner och diagnostiska kriterier (2018)
• Impact of resuscitation fluid bag size availability on volume of fluid administration in the intensive care unit (2018)
• The SSAI fully supports the suspension of hydroxyethyl-starch solutions commissioned by the European Medicines Agency (2018)
• Should the Aminoglycoside β-Lactam Combination Be Abandoned in All Severely Ill Patients With Presumed Gram-Negative Infection? (2018)
• Dynamics of Endotoxin, Inflammatory Variables, and Organ Dysfunction After Treatment With Antibiotics in an Escherichia coli Porcine Intensive Care Sepsis Model (2018)
• Protective ventilation reduces Pseudomonas aeruginosa growth in lung tissue in a porcine pneumonia model (2017)
• Protective ventilation reduces Pseudomonas aeruginosa growth in lung tissue in a porcine pneumonia model (2017)
• Long-term mortality after severe sepsis and septic shock in Swedish intensive care units 2005-2015 (2017)
• The impact of hydrocortisone treatment on neutrophil gelatinase-associated lipocalin release in porcine endotoxemic shock (2017)
• Rapid Bolus Administration Does Not Increase the Extravasation Rate of Albumin (2017)
• Emergency intraosseous access (2016)
• Evaluation of intraosseous sampling for measurements of alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, creatinine kinase, gamma-glutamyl transferase and lactate dehydrogenase. (2016)
• Pre-existing systemic inflammation attenuates bacterial clearance by the liver in porcine abdominal sepsis (2016)
• Epidemiology of secondary fluid bolus therapy for infection-associated hypotension (2016)
• Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco (R) LPS Adsorber (2016)
• Performance of plasma calprotectin as a biomarker of early sepsis (2016)
• Analysis of Thromboelastography, PT, APTT and Fibrinogen in Intraosseous and Venous Samples (2016)
• Initial levels of organ failure, microbial findings and mortality in intensive care-treated primary, secondary and tertiary sepsis (2015)
• Troponin I can be Determined in Intraosseous Aspirates in a Porcine Shock Model (2015)
• Intraosseös provtagning kan vara värdefull i akuta lägen (2015)
• Intraosseös provtagning kan vara värdefull i akuta lägen (2015)
• Primary fluid bolus therapy for infection-associated hypotension in the emergency department (2015)
• Hemodynamic management of septic shock (2015)
• Effect of perfusion pressure on the splanchnic circulation after CPB (2015)
• Evaluating the effects of protective ventilation on organ-specific cytokine production in porcine experimental postoperative sepsis (2015)
• Intraosseous and intravenous administration of antibiotics yields comparable plasma concentrations during experimental septic shock (2015)
• Effects of Tigecycline and Doxycycline on Inflammation and Hemodynamics in Porcine Endotoxemia (2015)
• Aerobic capacity at cardio-pulmonary exercise testing and survival with and without liver transplantation in patients with chronic liver disease (2014)
• Initial and Extended Use of Femoral Versus Nonfemoral Double-Lumen Vascular Catheters and Catheter-Related Infection During Continuous Renal Replacement Therapy (2014)
• Clinically manifest thromboembolic complications of femoral vein catheterization for continuous renal replacement therapy (2014)
• Neutrophil gelatinase-associated lipocalin after off pump versus on pump coronary artery surgery (2014)
• Beneficial Antimicrobial Effect of the Addition of an Aminoglycoside to a β-Lactam Antibiotic in an E. coli Porcine Intensive Care Severe Sepsis Model. (2014)
• Intraosseous Samples Can Be Used for CreatinineMeasurements - An Experimental Study in the Anaesthetised Pig (2014)
• Analysis of intraosseous samples in endotoxemic shock (2014)
• Pulse pressure variation-guided fluid therapy after cardiac surgery (2014)
• Serum leptin is decreased thirty days after surgery (2014)
• Early acid-base and blood pressure effects of continuous renal replacement therapy intensity in patients with metabolic acidosis (2013)
• Endotoxin tolerance variation over 24 h during porcine endotoxemia (2013)
• Intraosseous samples can be used for opioid measurements (2013)
• Pilot alternating treatment design study of the splanchnic metabolic effects of two mean arterial pressure targets during cardiopulmonary bypass (2013)
• Arterial carbon dioxide tension and outcome in patients admitted to the intensive care unit after cardiac arrest (2013)
• Simple translational equations to compare illness severity scores in intensive care trials (2013)
• Lung protective ventilation induces immunotolerance and nitric oxide metabolites in porcine experimental postoperative sepsis (2013)
• Near-infrared spectroscopy of the thenar eminence to estimate forearm blood flow (2013)
• Differences in Organ Dysfunction in Endotoxin Tolerant Pigs Under Intensive Care Exposed to a Second Hit of Endotoxin (2012)
• Benchmarking participant recruitment in intensive care clinical trials (2012)
• Near-infrared spectroscopy of the thenar eminence (2012)
• Prævalens af delvis behandlet supralabial hirsutisme hos diktatorer (2012)
• Near infrared spectroscopy (NIRS) of the thenar eminence in anesthesia and intensive care (2012)
• Relationship between illness severity scores in acute kidney injury (2012)
• Analysis of intraosseous samples using point of care technology (2012)
• Counteraction of early circulatory derangement by administration of low dose steroid treatment at the onset of established endotoxemic shock is not directly mediated by TNF-α and IL-6 (2012)
• Xigris 2011 (2011)
• Septic acute kidney injury (2011)
• Significant differences when using creatinine, modification of diet in renal disease, or cystatin C for estimating glomerular filtration rate in ICU patients (2011)
• Intraosseous blood aspirates analysed by a portable cartridge-based device (2011)
• The brain is a source of S100B increase during endotoxemia in the pig (2010)
• Inflammatory and circulatory effects of the reduction of endotoxin concentration in established porcine endotoxemic shock (2009)
• Effect of a single dose of tobramycin on systemic inflammatory response-induced acute kidney injury in a 6-hour porcine model (2009)
• Dagens svenska metoder för att mäta njurfunktion måste bli bättre (2008)
• Effect of the Administration Rate on the Biological Responses To A Fixed Dose of Endotoxin in the Anesthetized Pig (2008)
• F2-isoprostane, inflammation, cardiac function and oxygenation in the endotoxaemic pig (2008)
• Inflammatory, coagulatory and circulatory responses to logarithmic increases in the endotoxin dose in the anaesthetised pig (2006)
• Slight Increase of Serum S-100B During Porcine Endotoxemic Shock May Indicate Blood-Brain Barrier Damage. (2005)
• Early endotoxin-mediated haemostatic and inflammatory responses in the clopidogrel-treated pig (2005)
• Early endotoxin-mediated haemostatic and inflammatory responses in the clopidogrel-treated pig (2005)
• Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock (2004)
• Anti-inflammatory effects of the antibiotics ceftazidime and tobramycin in porcine endotoxin shock (2004)
• Endotoxin neutralisation and anti-inflammatory effects by tobramycin and ceftazidime in porcine endotoxic shock (2003)
• One-year functional recovery from severe Covid-19 is severely affected in the Swedish intensive care and hospital admitted working age cohort
• Association of sepsis with long-term mortality and causes of death in the Swedish intensive care cohort
• Plasma expansion and renal perfusion in critical COVID-19 with AKI: a prospective case control study
• Prone Positioning ventilation’s effect on abdominal organs: A clinical imaging study
• Endotoxemia versus pneumonia or lung-protective ventilation decelerates the decrease in plasma myostatin levels in a porcine intensive care model
• Intravenous anti-P. aeruginosa IgY antibodies increase bacterial concentration in porcine septic shock with bacteremia
• Mode of Bacterial Killing Affects the Inflammatory Response and Associated Organ Dysfunctions in a Porcine E. coli Intensive Care Sepsis Model
• Enhanced Bacterial Clearance at a Secondary Sepsis Challenge in an Endotoxin-tolerant Porcine Intensive Care Model
• Exposure to Mechanical Ventilation and Endotoxin for 24 Hours Before Infection Influences Pseudomonas Aeruginosa Growth During Experimental Porcine Ventilator-Associated Pneumonia
• Protective Ventilation Reduces Pseudomonas Aeruginosa Growth in a Porcine Pneumonia Model
• Endotoxin challenge models: Model-based translation from piglets to healthy volunteers
• Physiological response to endotoxin: Linking hemodynamic and respiratory longitudinal changes through modelling
• Mitochondrial stress in early experimental sepsis revealed by electron transport chain inhibition

Kapitel

• Oxidative stress in animal models with special reference to esperimental porcine endotoxemia (2011)