Fredrik Jernerén

Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A. David et al.

Ingår i Journal of Alzheimer's Disease, s. 189-197, 2019

• DOI för Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

Homocysteine concentrations in the cognitive progression of Alzheimer's disease

Farina, Nicolas; Jernerén, Fredrik; Turner, Cheryl; Hart, Kathryn et al.

Ingår i Experimental Gerontology, s. 146-150, 2017

• DOI för Homocysteine concentrations in the cognitive progression of Alzheimer's disease

Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment.

Oulhaj, Abderrahim; Jernerén, Fredrik; Refsum, Helga; Smith, A David et al.

Ingår i Journal of Alzheimer's Disease, s. 547-57, 2016

• DOI för Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment.

A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici.

Oliw, Ernst H; Aragó, Marc; Chen, Yang; Jernerén, Fredrik

Ingår i Journal of Lipid Research, s. 1518-1528, 2016

• DOI för A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici.

Post-sampling release of free fatty acids -: effects of heat stabilization and methods of euthanasia

Jernerén, Fredrik; Söderquist, Marcus; Karlsson, Oskar

Ingår i Journal of pharmacological and toxicological methods, s. 13-20, 2015

• DOI för Post-sampling release of free fatty acids -: effects of heat stabilization and methods of euthanasia

Brain atrophy in cognitively impaired elderly: the importance of long-chain ω-3 fatty acids and B vitamin status in a randomized controlled trial.

Jernerén, Fredrik; Elshorbagy, Amany K; Oulhaj, Abderrahim; Smith, Stephen M et al.

Ingår i American Journal of Clinical Nutrition, s. 215-21, 2015

• DOI för Brain atrophy in cognitively impaired elderly: the importance of long-chain ω-3 fatty acids and B vitamin status in a randomized controlled trial.

The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB

Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Lipids, s. 707-717, 2012

• DOI för The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB

Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae

Jernerén, Fredrik; Eng, Felipe; Hamberg, Mats; Oliw, Ernst H

Ingår i Lipids, s. 65-73, 2012

• DOI för Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae

Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus

Jernerén, Fredrik; Garscha, Ulrike; Hoffmann, Inga; Hamberg, Mats et al.

Ingår i Biochimica et Biophysica Acta, s. 503-507, 2010

• DOI för Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus

Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus: studies on pathogenicity, stereochemistry, and oxygenation mechanisms

Jernerén, Fredrik; Sesma, Ane; Francheschetti, Marina; Hamberg, Mats et al.

Ingår i Journal of Biological Chemistry, s. 5308-5316, 2010

• DOI för Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus: studies on pathogenicity, stereochemistry, and oxygenation mechanisms

Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus

Jernerén, Fredrik; Hoffmann, Inga; Oliw, Ernst H

Ingår i Archives of Biochemistry and Biophysics, s. 67-73, 2010

• DOI för Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus

Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial

Kacerova, Tereza; Yates, Abi G.; Dai, Jiayi; Shepherd, Dawn et al.

Ingår i Alzheimer's & Dementia, 2025

• DOI för Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial
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Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment

Holmes, Holly E.; Valentin, Rafael E.; Jernerén, Fredrik; Loots, Celeste A. de Jager et al.

Ingår i Aging Cell, 2024

• DOI för Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment
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Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults

Elkafrawy, Hagar; Mehanna, Radwa; Ali, Fayrouz; Barghash, Ayman et al.

Ingår i Amino Acids, s. 1623-1634, 2021

• DOI för Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults
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ω-3 fatty acids and their interactions

Smith, A. David; Jernerén, Fredrik; Refsum, Helga

Ingår i American Journal of Clinical Nutrition, s. 775-778, 2021

• DOI för ω-3 fatty acids and their interactions

Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults

Alshahawy, Rasha; El Habachi, Nihal; Allam, Eman; Jernerén, Fredrik et al.

Ingår i Nutrition, 2021

• DOI för Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults

Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial

Kacerova, Tereza; Yates, Abi G.; Dai, Jiayi; Shepherd, Dawn et al.

Ingår i Alzheimer's & Dementia, 2025

• DOI för Role of B vitamins in modulating homocysteine and metabolic pathways linked to brain atrophy: Metabolomics insights from the VITACOG trial
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Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment

Holmes, Holly E.; Valentin, Rafael E.; Jernerén, Fredrik; Loots, Celeste A. de Jager et al.

Ingår i Aging Cell, 2024

• DOI för Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment
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Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults

Elkafrawy, Hagar; Mehanna, Radwa; Ali, Fayrouz; Barghash, Ayman et al.

Ingår i Amino Acids, s. 1623-1634, 2021

• DOI för Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults
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ω-3 fatty acids and their interactions

Smith, A. David; Jernerén, Fredrik; Refsum, Helga

Ingår i American Journal of Clinical Nutrition, s. 775-778, 2021

• DOI för ω-3 fatty acids and their interactions

Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults

Alshahawy, Rasha; El Habachi, Nihal; Allam, Eman; Jernerén, Fredrik et al.

Ingår i Nutrition, 2021

• DOI för Changes in plasma fatty acids and related biomarkers during transition to an exclusively plant- and fish-based diet in healthy adults

Pesticide-induced multigenerational effects on amphibian reproduction and metabolism

Karlsson, Oskar; Svanholm, Sofie; Eriksson, Andreas; Chidiac, Joseph et al.

Ingår i Science of the Total Environment, 2021

• DOI för Pesticide-induced multigenerational effects on amphibian reproduction and metabolism

Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study

Tofiq, Avin; Zetterberg, Henrik; Blennow, Kaj; Basun, Hans et al.

Ingår i Journal of Alzheimer's Disease, s. 1291-1301, 2021

• DOI för Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study

Exhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists

Olsen, Thomas; Sollie, Ove; Nurk, Eha; Turner, Cheryl et al.

Ingår i Frontiers in Physiology, 2020

• DOI för Exhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists
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Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A. David et al.

Ingår i Journal of Alzheimer's Disease, s. 189-197, 2019

• DOI för Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain

Elshorbagy, Amany K.; Samocha-Bonet, Dorit; Jernerén, Fredrik; Turner, Cheryl et al.

Ingår i Journal of Nutrition, s. 1073-1080, 2018

• DOI för Food Overconsumption in Healthy Adults Triggers Early and Sustained Increases in Serum Branched-Chain Amino Acids and Changes in Cysteine Linked to Fat Gain

Protein intake in the early recovery period after exhaustive exercise improves performance the following day.

Sollie, Ove; Jeppesen, Per Bendix; Tangen, Daniel Steensen; Jernerén, Fredrik et al.

Ingår i Journal of applied physiology, s. 1731-1742, 2018

• DOI för Protein intake in the early recovery period after exhaustive exercise improves performance the following day.

Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells

Pierozan, Paula; Jernerén, Fredrik; Karlsson, Oskar

Ingår i Archives of Toxicology, s. 1729-1739, 2018

• DOI för Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells
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Purification and site-directed mutagenesis of linoleate 9S-dioxygenase-allene oxide synthase of Fusarium oxysporum confirms the oxygenation mechanism

Chen, Yang; Jernerén, Fredrik; Oliw, Ernst

Ingår i Archives of Biochemistry and Biophysics, s. 24-29, 2017

• DOI för Purification and site-directed mutagenesis of linoleate 9S-dioxygenase-allene oxide synthase of Fusarium oxysporum confirms the oxygenation mechanism

Homocysteine concentrations in the cognitive progression of Alzheimer's disease

Farina, Nicolas; Jernerén, Fredrik; Turner, Cheryl; Hart, Kathryn et al.

Ingår i Experimental Gerontology, s. 146-150, 2017

• DOI för Homocysteine concentrations in the cognitive progression of Alzheimer's disease

Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells.

Haj-Yasein, Nadia Nabil; Berg, Ole; Jernerén, Fredrik; Refsum, Helga et al.

Ingår i Biochimica et Biophysica Acta, s. 623-635, 2017

• DOI för Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells.

Amino acid changes during transition to a vegan diet supplemented with fish in healthy humans.

Elshorbagy, Amany; Jernerén, Fredrik; Basta, Marianne; Basta, Caroline et al.

Ingår i European Journal of Nutrition, s. 1953-1962, 2017

• DOI för Amino acid changes during transition to a vegan diet supplemented with fish in healthy humans.

The Choice of Euthanasia Method Affects Metabolic Serum Biomarkers

Pierozan, Paula; Jernerén, Fredrik; Ransome, Yusuf; Karlsson, Oskar

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 113-118, 2017

• DOI för The Choice of Euthanasia Method Affects Metabolic Serum Biomarkers

Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans.

Elshorbagy, A K; Jernerén, Fredrik; Samocha-Bonet, D; Refsum, H et al.

Ingår i Nutrition & Diabetes, 2016

• DOI för Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans.

Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.

Elshorbagy, Amany K; Jernerén, Fredrik; Scudamore, Cheryl L; McMurray, Fiona et al.

Ingår i PLOS ONE, 2016

• DOI för Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.

Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

Zhang, Weihua; Jernerén, Fredrik; Lehne, Benjamin C; Chen, Ming-Huei et al.

Ingår i Thrombosis and haemostasis, s. 1041-1049, 2016

• DOI för Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment.

Oulhaj, Abderrahim; Jernerén, Fredrik; Refsum, Helga; Smith, A David et al.

Ingår i Journal of Alzheimer's Disease, s. 547-57, 2016

• DOI för Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment.

A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici.

Oliw, Ernst H; Aragó, Marc; Chen, Yang; Jernerén, Fredrik

Ingår i Journal of Lipid Research, s. 1518-1528, 2016

• DOI för A new class of fatty acid allene oxide formed by the DOX-P450 fusion proteins of human and plant pathogenic fungi, C. immitis and Z. tritici.

Post-sampling release of free fatty acids -: effects of heat stabilization and methods of euthanasia

Jernerén, Fredrik; Söderquist, Marcus; Karlsson, Oskar

Ingår i Journal of pharmacological and toxicological methods, s. 13-20, 2015

• DOI för Post-sampling release of free fatty acids -: effects of heat stabilization and methods of euthanasia

Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid

Wennman, Anneli; Jernerén, Fredrik; Magnuson, Ann; Oliw, Ernst H

Ingår i Archives of Biochemistry and Biophysics, s. 87-95, 2015

• DOI för Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid

Brain atrophy in cognitively impaired elderly: the importance of long-chain ω-3 fatty acids and B vitamin status in a randomized controlled trial.

Jernerén, Fredrik; Elshorbagy, Amany K; Oulhaj, Abderrahim; Smith, Stephen M et al.

Ingår i American Journal of Clinical Nutrition, s. 215-21, 2015

• DOI för Brain atrophy in cognitively impaired elderly: the importance of long-chain ω-3 fatty acids and B vitamin status in a randomized controlled trial.

Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes

Hoffmann, Inga; Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Journal of Lipid Research, s. 2113-2123, 2014

• DOI för Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes

Expression of Fusion Proteins of Aspergillus terreus Reveals a Novel Allene Oxide Synthase

Hoffmann, Inga; Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Journal of Biological Chemistry, s. 11459-11469, 2013

• DOI för Expression of Fusion Proteins of Aspergillus terreus Reveals a Novel Allene Oxide Synthase

Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino Acid

Wennman, Anneli; Jernerén, Fredrik; Hamberg, Mats; Oliw, Ernst H

Ingår i Journal of Biological Chemistry, s. 31757-31765, 2012

• DOI för Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino Acid

The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB

Jernerén, Fredrik; Oliw, Ernst H.

Ingår i Lipids, s. 707-717, 2012

• DOI för The Fatty Acid 8,11-Diol Synthase of Aspergillus fumigatus is Inhibited by Imidazole Derivatives and Unrelated to PpoB

Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae

Jernerén, Fredrik; Eng, Felipe; Hamberg, Mats; Oliw, Ernst H

Ingår i Lipids, s. 65-73, 2012

• DOI för Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae

Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain: a comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase

Hoffmann, Inga; Jernerén, Fredrik; Garscha, Ulrike; Oliw, Ernst H.

Ingår i Archives of Biochemistry and Biophysics, s. 216-222, 2011

• DOI för Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain: a comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase

Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases

Oliw, Ernst H.; Wennman, Anneli; Hoffmann, Inga; Garscha, Ulrike et al.

Ingår i Journal of Lipid Research, s. 1995-2004, 2011

• DOI för Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases

Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms

Oliw, Ernst H.; Jernerén, Fredrik; Hoffmann, Inga; Sahlin, Margareta et al.

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 138-147, 2011

• DOI för Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms

Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus

Jernerén, Fredrik; Garscha, Ulrike; Hoffmann, Inga; Hamberg, Mats et al.

Ingår i Biochimica et Biophysica Acta, s. 503-507, 2010

• DOI för Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus

Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus: studies on pathogenicity, stereochemistry, and oxygenation mechanisms

Jernerén, Fredrik; Sesma, Ane; Francheschetti, Marina; Hamberg, Mats et al.

Ingår i Journal of Biological Chemistry, s. 5308-5316, 2010

• DOI för Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus: studies on pathogenicity, stereochemistry, and oxygenation mechanisms

Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus

Jernerén, Fredrik; Hoffmann, Inga; Oliw, Ernst H

Ingår i Archives of Biochemistry and Biophysics, s. 67-73, 2010

• DOI för Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus

Identification of dioxygenases required for Aspergillus development: Studies of products, stereochemistry, and the reaction mechanism

Garscha, Ulrike; Jernerén, Fredrik; Chung, D.; Keller, N.P. et al.

Ingår i Journal of Biological Chemistry, s. 34707-34718, 2007

• DOI för Identification of dioxygenases required for Aspergillus development: Studies of products, stereochemistry, and the reaction mechanism

Novel Fatty Acid Dioxygenases of Human and Plant Pathogenic Fungi: Studies by Gene Deletion and Expression

Jernerén, Fredrik

2011

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