Johan Heldin

The method developer's guide to oligonucleotide design

Wenson, Leonie; Leino, Mattias; Jarvius, Malin; Heldin, Johan et al.

Ingår i Expert Review of Proteomics, s. 65-80, 2024

• DOI för The method developer's guide to oligonucleotide design
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Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI för Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
• Ladda ner fulltext (pdf) av Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

Wåhlén, Erik; Lennartsson, Johan; Heldin, Johan

Ingår i Biochemistry and Biophysics Reports, 2024

• DOI för Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling
• Ladda ner fulltext (pdf) av Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells

Rubin Sander, Marie; Tsiatsiou, Agni Karolina; Wang, Kehuan; Papadopoulos, Natalia et al.

Ingår i Growth Factors, s. 147-160, 2024

• DOI för PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells
• Ladda ner fulltext (pdf) av PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells

Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Bivehed, Erik; Hellman, Björn; Wenson, Leonie; Stenerlöw, Bo et al.

Ingår i Nucleic Acids Research, 2024

• DOI för Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling
• Ladda ner fulltext (pdf) av Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Olsson, Frida; Wåhlén, Erik; Heldin, Johan; Söderberg, Ola et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, 2024

• DOI för Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation
• Ladda ner fulltext (pdf) av Crosstalk between 1,25(OH)₂-Vitamin D₃ and the growth factors EGF and PDGF-BB: Impact on CYP24A1 expression and cell proliferation

Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

Wåhlén, Erik; Lennartsson, Johan; Heldin, Johan

Ingår i Biochemistry and Biophysics Reports, 2024

• DOI för Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling
• Ladda ner fulltext (pdf) av Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells

Rubin Sander, Marie; Tsiatsiou, Agni Karolina; Wang, Kehuan; Papadopoulos, Natalia et al.

Ingår i Growth Factors, s. 147-160, 2024

• DOI för PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells
• Ladda ner fulltext (pdf) av PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells

Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Bivehed, Erik; Hellman, Björn; Wenson, Leonie; Stenerlöw, Bo et al.

Ingår i Nucleic Acids Research, 2024

• DOI för Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling
• Ladda ner fulltext (pdf) av Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling

Activated EGFR and PDGFR internalize in separate vesicles and downstream AKT and ERK1/2 signaling are differentially impacted by cholesterol depletion

Wåhlén, Erik; Olsson, Frida; Raykova, Doroteya; Söderberg, Ola et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 195-201, 2023

• DOI för Activated EGFR and PDGFR internalize in separate vesicles and downstream AKT and ERK1/2 signaling are differentially impacted by cholesterol depletion
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Analysis of context-specific KRAS-effector (sub)complexes in Caco-2 cells

Ternet, Camille; Junk, Philipp; Sevrin, Thomas; Catozzi, Simona et al.

Ingår i Life Science Alliance, 2023

• DOI för Analysis of context-specific KRAS-effector (sub)complexes in Caco-2 cells
• Ladda ner fulltext (pdf) av Analysis of context-specific KRAS-effector (sub)complexes in Caco-2 cells

A method for Boolean analysis of protein interactions at a molecular level

Raykova, Doroteya; Kermpatsou, Despoina; Malmqvist, Tony; Harrison, Philip J et al.

Ingår i Nature Communications, 2022

• DOI för A method for Boolean analysis of protein interactions at a molecular level
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Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase, SRC and AKT signaling

Wåhlén, Erik; Olsson, Frida; Söderberg, Ola; Lennartsson, Johan et al.

Ingår i Cellular Signalling, 2022

• DOI för Differential impact of lipid raft depletion on platelet-derived growth factor (PDGF)-induced ERK1/2 MAP-kinase, SRC and AKT signaling
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Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level

Lönn, Peter; Al-Amin, Abdullah; Doulabi, Ehsan Manouchehri; Heldin, Johan et al.

Ingår i Communications Biology, 2021

• DOI för Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level
• Ladda ner fulltext (pdf) av Image-based high-throughput mapping of TGF-beta-induced phosphocomplexes at a single-cell level

Optimization of proximity-dependent initiation of hybridization chain reaction for improved performance

Leino, Mattias; Heldin, Johan; Rubin Sander, Marie; Kermpatsou, Despoina et al.

Ingår i Molecular Systems Design & Engineering, s. 1058-1065, 2019

• DOI för Optimization of proximity-dependent initiation of hybridization chain reaction for improved performance
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Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling

Heldin, Johan; Rubin Sander, Marie; Leino, Mattias; Thomsson, Sara et al.

Ingår i Experimental Cell Research, s. 69-79, 2019

• DOI för Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling
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Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes

Klaesson, Axel; Grannas, Karin; Ebai, Tonge; Heldin, Johan et al.

Ingår i Scientific Reports, 2018

• DOI för Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes
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Detection of post-translational modifications using solid-phase proximity ligation assay

de Oliveira, Felipe Marques Souza; Mereiter, Stefan; Lönn, Peter; Siart, Benjamin et al.

Ingår i New Biotechnology, s. 51-59, 2018

• DOI för Detection of post-translational modifications using solid-phase proximity ligation assay

FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

Heldin, Johan; O'Callaghan, Paul; Hernández Vera, Rodrigo; Fredlund Fuchs, Peder et al.

Ingår i Cellular Signalling, s. 125-132, 2017

• DOI för FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation

The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration

Blom, Magdalena; Reis, Katarina; Heldin, Johan; Kreuger, Johan et al.

Ingår i Experimental Cell Research, s. 255-264, 2017

• DOI för The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration

Proximity-dependent initiation of hybridization chain reaction

Koos, Björn; Cane, Gaëlle; Grannas, Karin; Löf, Liza et al.

Ingår i Nature Communications, 2015

• DOI för Proximity-dependent initiation of hybridization chain reaction
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Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b

Sundström, Görel; Larsson, Tomas A.; Xu, Bo; Heldin, Johan et al.

Ingår i Frontiers in Neuroscience, 2013

• DOI för Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b
• Ladda ner fulltext (pdf) av Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b

Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Le Jan, Sébastien; Hayashi, Makoto; Kasza, Zsolt; Eriksson, Inger et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1255-1263, 2012

• DOI för Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes

Sundström, Görel; Xu, Bo; Larsson, Tomas A; Heldin, Johan et al.

Ingår i General and Comparative Endocrinology, s. 322-331, 2012

• DOI för Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes

Exocyst Complex Component 3-like 2 (EXOC3L2) Associates with the Exocyst Complex and Mediates Directional Migration of Endothelial Cells

Barkefors, Irmeli; Fredlund Fuchs, Peder; Heldin, Johan; Bergström, Tobias et al.

Ingår i Journal of Biological Chemistry, s. 24189-24199, 2011

• DOI för Exocyst Complex Component 3-like 2 (EXOC3L2) Associates with the Exocyst Complex and Mediates Directional Migration of Endothelial Cells

Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

Larsson, Erik; Fredlund Fuchs, Peder; Heldin, Johan; Barkefors, Irmeli et al.

Ingår i Genome Medicine, s. 108, 2009

• DOI för Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

The method developer's guide to oligonucleotide design

Wenson, Leonie; Leino, Mattias; Jarvius, Malin; Heldin, Johan et al.

Ingår i Expert Review of Proteomics, s. 65-80, 2024

• DOI för The method developer's guide to oligonucleotide design
• Ladda ner fulltext (pdf) av The method developer's guide to oligonucleotide design

Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

Heldin, Johan

2014

• Ladda ner fulltext (pdf) av Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

High-throughput in situ mapping of phosphorylated protein complexes across the cell cycle and in response to drugs

Lönn, Peter; Al-Amin, Rasel A.; Heldin, Johan; Gallini, Radiosa et al.