Michael Vanlandewijck

A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck, Michael; He, Liqun; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Ingår i Nature, s. 475-480, 2018

• DOI för A molecular atlas of cell types and zonation in the brain vasculature

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

He, Liqun; Vanlandewijck, Michael; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Ingår i Scientific Data, 2018

• DOI för Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types
• Ladda ner fulltext (pdf) av Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

Analysis of the brain mural cell transcriptome

He, Liqun; Vanlandewijck, Michael; Raschperger, Elisabeth; Mae, Maarja Andaloussi et al.

Ingår i Scientific Reports, 2016

• DOI för Analysis of the brain mural cell transcriptome
• Ladda ner fulltext (pdf) av Analysis of the brain mural cell transcriptome

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Vanlandewijck, Michael; Lebouvier, Thibaud; Mae, Maarja Andaloussi; Nahar, Khayrun et al.

Ingår i PLOS ONE, 2015

• DOI för Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification
• Ladda ner fulltext (pdf) av Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Regulation of EMT by TGFβ in cancer

Heldin, Carl-Henrik; Vanlandewijck, Michael; Moustakas, Aristidis

Ingår i FEBS Letters, s. 1959-1970, 2012

• DOI för Regulation of EMT by TGFβ in cancer

SIK phosphorylates and degrades Par3 to mediate tight junction disassembly during epithelial-mesenchymal transition

Vanlandewijck, Michael; Lomnytska, Marta; Busch, Christer; Heldin, Carl-Henrik et al.

2011

Diversification of TGF-β Signaling in Homeostasis and Disease

Vanlandewijck, Michael

2011

• Ladda ner fulltext (pdf) av Diversification of TGF-β Signaling in Homeostasis and Disease

Notch signaling is necessary for epithelial growth arrest by TGF-beta

Niimi, Hideki; Pardali, Katerina; Vanlandewijck, Michael; Heldin, Carl-Henrik et al.

Ingår i Journal of Cell Biology, s. 695-707, 2007

• DOI för Notch signaling is necessary for epithelial growth arrest by TGF-beta

A reference protein atlas of the adult mouse brain vasculature

He, Liqun; Johansson, Henrik J.; Vazquez-Liebanas, Elisa; Liu, Jianping et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI för A reference protein atlas of the adult mouse brain vasculature
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Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer's, CADASIL, and Traumatic Brain Injury

Bjørnholm, K. D.; Li, H.; Del Gaudio, F.; Mocci, G. et al.

Ingår i Nature Communications, 2026

• DOI för Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer's, CADASIL, and Traumatic Brain Injury
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Nerve growth factor responsive elements modulate immune cell inflammation and are dysregulated in an Alzheimer's disease mouse model

Gera, Ruchi; Mocci, Giuseppe; Tambaro, Simone; Vanlandewijck, Michael et al.

Ingår i Frontiers in Immunology, 2026

• DOI för Nerve growth factor responsive elements modulate immune cell inflammation and are dysregulated in an Alzheimer's disease mouse model
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A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Pietilä, Riikka; Genové, Guillem; Mocci, Giuseppe; Miao, Yuyang et al.

Ingår i EMBO Reports, s. 5326-5359, 2025

• DOI för A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
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Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques

Sukhavasi, Katyayani; Mocci, Giuseppe; Ma, Lijiang; Hodonsky, Chani J. et al.

Ingår i Nature Cardiovascular Research, s. 412-432, 2025

• DOI för Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques
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A reference protein atlas of the adult mouse brain vasculature

He, Liqun; Johansson, Henrik J.; Vazquez-Liebanas, Elisa; Liu, Jianping et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI för A reference protein atlas of the adult mouse brain vasculature
• Ladda ner fulltext (pdf) av A reference protein atlas of the adult mouse brain vasculature

Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer's, CADASIL, and Traumatic Brain Injury

Bjørnholm, K. D.; Li, H.; Del Gaudio, F.; Mocci, G. et al.

Ingår i Nature Communications, 2026

• DOI för Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer's, CADASIL, and Traumatic Brain Injury
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Nerve growth factor responsive elements modulate immune cell inflammation and are dysregulated in an Alzheimer's disease mouse model

Gera, Ruchi; Mocci, Giuseppe; Tambaro, Simone; Vanlandewijck, Michael et al.

Ingår i Frontiers in Immunology, 2026

• DOI för Nerve growth factor responsive elements modulate immune cell inflammation and are dysregulated in an Alzheimer's disease mouse model
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A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Pietilä, Riikka; Genové, Guillem; Mocci, Giuseppe; Miao, Yuyang et al.

Ingår i EMBO Reports, s. 5326-5359, 2025

• DOI för A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
• Ladda ner fulltext (pdf) av A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver

Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques

Sukhavasi, Katyayani; Mocci, Giuseppe; Ma, Lijiang; Hodonsky, Chani J. et al.

Ingår i Nature Cardiovascular Research, s. 412-432, 2025

• DOI för Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques
• Ladda ner fulltext (pdf) av Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques

Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage

Vázquez-Liébanas, Elisa; Mocci, Giuseppe; Li, Weihan; Laviña, Bàrbara et al.

Ingår i Cell Reports, 2024

• DOI för Mosaic deletion of claudin-5 reveals rapid non-cell-autonomous consequences of blood-brain barrier leakage
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A brain-specific angiogenic mechanism enabled by tip cell specialization

Schevenels, Giel; Cabochette, Pauline; America, Michelle; Vandenborne, Arnaud et al.

Ingår i Nature, s. 863-871, 2024

• DOI för A brain-specific angiogenic mechanism enabled by tip cell specialization
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A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

Bjornholm, Katrine Dahl; Del Gaudio, Francesca; Li, Hao; Li, Weihan et al.

Ingår i Cell Reports Methods, 2023

• DOI för A robust and efficient microvascular isolation method for multimodal characterization of the mouse brain vasculature

Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation

Petkova, Milena; Kraft, Marle; Stritt, Simon; Martinez-Corral, Ines et al.

Ingår i Journal of Experimental Medicine, 2023

• DOI för Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation
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Molecular anatomy of adult mouse leptomeninges

Pietilä, Riikka; Del Gaudio, Francesca; He, Liqun; Vázquez-Liébanas, Elisa et al.

Ingår i Neuron, 2023

• DOI för Molecular anatomy of adult mouse leptomeninges
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A single-cell transcriptomic inventory of murine smooth muscle cells

Muhl, Lars; Mocci, Giuseppe; Pietilä, Riikka; Liu, Jianping et al.

Ingår i Developmental Cell, s. 2426-+, 2022

• DOI för A single-cell transcriptomic inventory of murine smooth muscle cells
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The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

Muhl, Lars; He, Liqun; Sun, Ying; Andaloussi Mäe, Maarja et al.

Ingår i Stem Cell Reports, s. 1089-1104, 2022

• DOI för The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells

Somuncular, Ece; Hauenstein, Julia; Khalkar, Prajakta; Johansson, Anne-Sofie et al.

Ingår i Stem Cell Reports, s. 1546-1560, 2022

• DOI för CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells
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ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Bernier-Latmani, Jeremiah; Mauri, Cristina; Marcone, Rachel; Renevey, Francois et al.

Ingår i Nature Communications, 2022

• DOI för ADAMTS18⁺ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels
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Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Mäe, Maarja Andaloussi; He, Liqun; Nordling, Sofia; Vazquez-Liebanas, Elisa et al.

Ingår i Circulation Research, 2021

• DOI för Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression

Wu, Dan; Wang, Sailan; Oliveira, Daniel V.; Del Gaudio, Francesca et al.

Ingår i Disease Models and Mechanisms, 2021

• DOI för The infantile myofibromatosis NOTCH3 L1519P mutation leads to hyperactivated ligand-independent Notch signaling and increased PDGFRB expression
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Integrative discovery of treatments for high-risk neuroblastoma

Almstedt, Elin; Elgendy, Ramy; Hekmati, Neda; Rosén, Emil et al.

Ingår i Nature Communications, 2020

• DOI för Integrative discovery of treatments for high-risk neuroblastoma
• Ladda ner fulltext (pdf) av Integrative discovery of treatments for high-risk neuroblastoma

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

Muhl, Lars; Genove, Guillem; Leptidis, Stefanos; Liu, Jianping et al.

Ingår i Nature Communications, 2020

• DOI för Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
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A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature

Xiang, Menglan; Grosso, Ruben Adrian; Takeda, Akira; Pan, Junliang et al.

Ingår i Frontiers in Cardiovascular Medicine, 2020

• DOI för A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature
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Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification

Nahar, Khayrun; Lebouvier, Thibaud; Andaloussi Mäe, Maarja; Konzer, Anne et al.

Ingår i Brain Pathology, s. 446-464, 2020

• DOI för Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification
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Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Engelbrecht, Eric; Levesque, Michel; He, Liqun; Vanlandewijck, Michael et al.

Ingår i eLIFE, 2020

• DOI för Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
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The protein kinase SIK downregulates the polarity protein Par3

Vanlandewijck, Michael; Dadras, Mahsa Shahidi; Lomnytska, Marta; Mahzabin, Tanzila et al.

Ingår i Oncotarget, s. 5716-5735, 2018

• DOI för The protein kinase SIK downregulates the polarity protein Par3

Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier

Mäe, Maarja Andaloussi; Li, Tian; Bertuzzi, Giacomo; Raschperger, Elisabeth et al.

Ingår i Scientific Reports, 2018

• DOI för Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
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Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Loganathan, Krishnapriya; Salem Said, Ebtisam; Winterrowd, Emily; Orebrand, Martina et al.

Ingår i PLOS ONE, 2018

• DOI för Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice
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A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck, Michael; He, Liqun; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Ingår i Nature, s. 475-480, 2018

• DOI för A molecular atlas of cell types and zonation in the brain vasculature

Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

He, Liqun; Vanlandewijck, Michael; Mäe, Maarja Andaloussi; Andrae, Johanna et al.

Ingår i Scientific Data, 2018

• DOI för Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types
• Ladda ner fulltext (pdf) av Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types

Analysis of the brain mural cell transcriptome

He, Liqun; Vanlandewijck, Michael; Raschperger, Elisabeth; Mae, Maarja Andaloussi et al.

Ingår i Scientific Reports, 2016

• DOI för Analysis of the brain mural cell transcriptome
• Ladda ner fulltext (pdf) av Analysis of the brain mural cell transcriptome

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

Carthy, Jon M.; Stoeter, Martin; Bellomo, Claudia; Vanlandewijck, Michael et al.

Ingår i Scientific Reports, 2016

• DOI för Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation
• Ladda ner fulltext (pdf) av Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Niaudet, Colin; Hofmann, Jennifer J.; Mae, Maarja A.; Jung, Bongnam et al.

Ingår i PLOS ONE, 2015

• DOI för Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Vanlandewijck, Michael; Lebouvier, Thibaud; Mae, Maarja Andaloussi; Nahar, Khayrun et al.

Ingår i PLOS ONE, 2015

• DOI för Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification
• Ladda ner fulltext (pdf) av Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling

Dahl, Markus; Maturi, Varun; Lönn, Peter; Papoutsoglou, Panagiotis et al.

Ingår i PLOS ONE, 2014

• DOI för Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling
• Ladda ner fulltext (pdf) av Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling

Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase

Lönn, Peter; Vanlandewijck, Michael; Raja, Erna; Kowanetz, Marcin et al.

Ingår i Journal of Biological Chemistry, s. 12867-12878, 2012

• DOI för Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase

TGFβ induces SIK to negatively regulate type I receptor kinase signaling

Kowanetz, Marcin; Lönn, Peter; Vanlandewijck, Michael; Kowanetz, Katarzyna et al.

Ingår i Journal of Cell Biology, s. 655-662, 2008

• DOI för TGFβ induces SIK to negatively regulate type I receptor kinase signaling

Notch signaling is necessary for epithelial growth arrest by TGF-beta

Niimi, Hideki; Pardali, Katerina; Vanlandewijck, Michael; Heldin, Carl-Henrik et al.

Ingår i Journal of Cell Biology, s. 695-707, 2007

• DOI för Notch signaling is necessary for epithelial growth arrest by TGF-beta

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

van Kuijk, Kim; Kuppe, Christoph; Betsholtz, Christer; Vanlandewijck, Michael et al.

Ingår i Cardiovascular Research, s. 1705-1715, 2019

• DOI för Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

Regulation of EMT by TGFβ in cancer

Heldin, Carl-Henrik; Vanlandewijck, Michael; Moustakas, Aristidis

Ingår i FEBS Letters, s. 1959-1970, 2012

• DOI för Regulation of EMT by TGFβ in cancer

Diversification of TGF-β Signaling in Homeostasis and Disease

Vanlandewijck, Michael

2011

• Ladda ner fulltext (pdf) av Diversification of TGF-β Signaling in Homeostasis and Disease

SIK phosphorylates and degrades Par3 to mediate tight junction disassembly during epithelial-mesenchymal transition

Vanlandewijck, Michael; Lomnytska, Marta; Busch, Christer; Heldin, Carl-Henrik et al.

2011

Angiopoietin 2 is a region-specific regulator of cerebrovascular architecture and blood-brain barrier function.

Li, Weihan; Vázquez-Liébanas, Elisa; Fébrissy, Channaëlle; Sauvé, Florent et al.