Christoph Metzendorf

The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration

Punga, Tanel; Larsson, Mårten; Mujica, Endrina; Melo, Fabio R. et al.

Ingår i Scientific Reports, 2026

• DOI för The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration
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Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Mazzaferro, Eugenia; Mujica, Endrina; Zhang, Hanqing; Emmanouilidou, Anastasia et al.

Ingår i Scientific Reports, s. 5408, 2025

• DOI för Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.
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Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

Mattis, Katia K; Krentz, Nicole A J; Metzendorf, Christoph; Abaitua, Fernando et al.

Ingår i Diabetologia, s. 674-694, 2023

• DOI för Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Wang, Zhe; Emmerich, Andrew; Pillon, Nicolas J; Moore, Tim et al.

Ingår i Nature Genetics, s. 1332-1344, 2022

• DOI för Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
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The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+cells indicate a high degree of conservation to mammalian palmitoylomes

Porcellato, Elena; Gonzalez-Sanchez, Juan Carlos; Ahlmann-Eltze, Constantin; Elsakka, Mahmoud Ali et al.

Ingår i PLOS ONE, 2022

• DOI för The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+cells indicate a high degree of conservation to mammalian palmitoylomes
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The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration

Punga, Tanel; Larsson, Mårten; Mujica, Endrina; Melo, Fabio R. et al.

Ingår i Scientific Reports, 2026

• DOI för The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration
• Ladda ner fulltext (pdf) av The C16orf87 protein is a subunit of the MIER corepressor complex controlling embryonic development and cell migration

Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Mazzaferro, Eugenia; Mujica, Endrina; Zhang, Hanqing; Emmanouilidou, Anastasia et al.

Ingår i Scientific Reports, s. 5408, 2025

• DOI för Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.
• Ladda ner fulltext (pdf) av Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.

Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

Mattis, Katia K; Krentz, Nicole A J; Metzendorf, Christoph; Abaitua, Fernando et al.

Ingår i Diabetologia, s. 674-694, 2023

• DOI för Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
• Ladda ner fulltext (pdf) av Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Wang, Zhe; Emmerich, Andrew; Pillon, Nicolas J; Moore, Tim et al.

Ingår i Nature Genetics, s. 1332-1344, 2022

• DOI för Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
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The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+cells indicate a high degree of conservation to mammalian palmitoylomes

Porcellato, Elena; Gonzalez-Sanchez, Juan Carlos; Ahlmann-Eltze, Constantin; Elsakka, Mahmoud Ali et al.

Ingår i PLOS ONE, 2022

• DOI för The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+cells indicate a high degree of conservation to mammalian palmitoylomes
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Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice

Nuernberger, Vincent; Mortoga, Sharif; Metzendorf, Christoph; Burkert, Christian et al.

Ingår i Cells, 2021

• DOI för Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice
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Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism

Metzendorf, Christoph; Wineberger, Katharina; Rausch, Jenny; Cigliano, Antonio et al.

Ingår i Molecules, s. 4141, 2020

• DOI för Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism
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Mitoferrin Deficiency Provokes An Ecdysone Synthesis Impairment And An Immune System Overreaction

Llorens, Jose; Metzendorf, Christoph; Missirlis, Fanis; Lind, Maria

Ingår i American Journal of Hematology, 2016

Mitochondrial iron supply is required for the developmental pulse of ecdysone biosynthesis that initiates metamorphosis in Drosophila melanogaster

Llorens, Jose V.; Metzendorf, Christoph; Missirlis, Fanis; Lind, Maria I.

Ingår i Journal of Biological Inorganic Chemistry, s. 1229-1238, 2015

The role of iron in the proliferation of Drosophila l(2)mbn cells

Metzendorf, Christoph; Lind, Maria I

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 442-446, 2010

• DOI för The role of iron in the proliferation of Drosophila l(2)mbn cells

Drosophila mitoferrin is essential for male fertility: Evidence for a role of mitochondrial iron metabolism during spermatogenesis

Metzendorf, Christoph; Lind, Maria I.

Ingår i BMC Developmental Biology, s. 68, 2010

• DOI för Drosophila mitoferrin is essential for male fertility: Evidence for a role of mitochondrial iron metabolism during spermatogenesis

Overexpression of Drosophila mitoferrin in l(2)mbn cells results in dysregulation of Fer1HCH expression

Metzendorf, Christoph; Wu, Wenlin; Lind, Maria I

Ingår i Biochemical Journal, s. 463-471, 2009

• DOI för Overexpression of Drosophila mitoferrin in l(2)mbn cells results in dysregulation of Fer1HCH expression

Mitochondrial Iron Metabolism: Study of mitoferrin in Drosophila melanogaster

Metzendorf, Christoph

2010

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Overexpression of dmrs, a Drosophila mitochondrial transporter, results in disruption of normal iron homeostasis in the Drosophila cell line mbn(2).

Metzendorf, Christoph; Wu, Wenlin; Lind, Maria I

2007

Overexpression of dmrs, a Drosophila homologue of yeast mrs3/4, results in increased expression of ferritin heavy chain homologue

Metzendorf, Christoph; Wu, Wenlin

2007

Overexpression of dmrs, a Drosophila mitochondrial transporter, results in disruption of normal iron homeostasis in the Drosophila cell line mbn(2).

Metzendorf, Christoph; Wu, Wenlin; Lind, Maria I

2007

The Drosophila mitoferrin gene-identification and characterisation

Metzendorf, Christoph

2009

Characterization of Drosophila mitoferrin and CG18317 mutants

Metzendorf, Christoph; Wiesenberger, Gerlinde; Lind, Maria I.

Kita crispants for systematic image-based genetic screens of complex traits in zebrafish larvae

Mazzaferro, Eugenia; Metzendorf, Christoph; Zhang, Hanqing; Mujica, Endrina et al.