Kristin Blom

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Mansoori, Sharmineh; Blom, Kristin; Andersson, Claes; Fryknäs, Mårten et al.

Ingår i Oncology Reports, 2026

• DOI för Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model
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Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Ingår i HemaSphere, 2025

• DOI för Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
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Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening

Gezelius, Henrik; Enblad, Anna Pia; Lundmark, Anders; Åberg, Martin et al.

Ingår i NAR Genomics and Bioinformatics, 2024

• DOI för Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening
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OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Mickols, Evgeniya; Meyer, Alina; Handin, Niklas; Stüwe, Malin et al.

Ingår i Scientific Reports, 2024

• DOI för OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
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Ex vivo assessment of chemotherapy sensitivity of colorectal cancer peritoneal metastases

Cashin, Peter; Söderström, Maria; Blom, Kristin; Artursson, Sara et al.

Ingår i British Journal of Surgery, s. 1080-1083, 2023

• DOI för Ex vivo assessment of chemotherapy sensitivity of colorectal cancer peritoneal metastases
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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Mansoori, Sharmineh; Blom, Kristin; Andersson, Claes; Fryknäs, Mårten et al.

Ingår i Oncology Reports, 2026

• DOI för Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model
• Ladda ner fulltext (pdf) av Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Enblad, Anna Pia; Krali, Olga; Gezelius, Henrik; Lundmark, Anders et al.

Ingår i HemaSphere, 2025

• DOI för Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients
• Ladda ner fulltext (pdf) av Ex vivo drug responses and molecular profiles of 597 pediatric acute lymphoblastic leukemia patients

Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening

Gezelius, Henrik; Enblad, Anna Pia; Lundmark, Anders; Åberg, Martin et al.

Ingår i NAR Genomics and Bioinformatics, 2024

• DOI för Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening
• Ladda ner fulltext (pdf) av Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening

OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Mickols, Evgeniya; Meyer, Alina; Handin, Niklas; Stüwe, Malin et al.

Ingår i Scientific Reports, 2024

• DOI för OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
• Ladda ner fulltext (pdf) av OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Ex vivo assessment of chemotherapy sensitivity of colorectal cancer peritoneal metastases

Cashin, Peter; Söderström, Maria; Blom, Kristin; Artursson, Sara et al.

Ingår i British Journal of Surgery, s. 1080-1083, 2023

• DOI för Ex vivo assessment of chemotherapy sensitivity of colorectal cancer peritoneal metastases
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Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients

Andersson, Claes; Ye, Jiawei; Blom, Kristin; Fryknäs, Mårten et al.

Ingår i Anti-Cancer Drugs, s. 92-102, 2023

• DOI för Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients
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Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome

Bjersand, Kathrine; Blom, Kristin; Sundström Poromaa, Inger; Stålberg, Karin et al.

Ingår i International Journal of Oncology, 2022

• DOI för Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome
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Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma

Nyberg, Frida; Blom, Kristin; Selvin, Tove; Rudfeldt, Jakob et al.

Ingår i Scientific Reports, 2022

• DOI för Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma
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Conditions for maintenance of hepatocyte differentiation and function in 3D cultures

Handin, Niklas; Mickols, Evgeniya; Ölander, Magnus; Rudfeldt, Jakob et al.

Ingår i iScience, 2021

• DOI för Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
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Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway

Andersson, Claes; Selvin, Tove; Blom, Kristin; Rubin, Jenny et al.

Ingår i Scientific Reports, 2020

• DOI för Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway
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Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

Blom, Kristin; Eriksson, Jenny; Berglund, Malin; Jarvius, Malin et al.

Ingår i BMC Research Notes, 2019

• DOI för Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition
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The genetically determined production of the alarmin eosinophil-derived neurotoxin is reduced in visceral leishmaniasis

Blom, Kristin; ElShafie, Amir Ibrahim; Jönsson, Ulla-Britt; Rönnelid, Johan et al.

Ingår i Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), s. 85-91, 2018

• DOI för The genetically determined production of the alarmin eosinophil-derived neurotoxin is reduced in visceral leishmaniasis

Targeting tumor cells based on Phosphodiesterase 3A expression

Nazir, Madiha; Senkowski, Wojciech; Nyberg, Frida; Blom, Kristin et al.

Ingår i Experimental Cell Research, s. 308-315, 2017

• DOI för Targeting tumor cells based on Phosphodiesterase 3A expression

The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation

Blom, Kristin; Senkowski, Wojciech; Jarvius, Malin; Berglund, Malin et al.

Ingår i Immunopharmacology and immunotoxicology, s. 199-210, 2017

• DOI för The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation

Predictive Value of Ex Vivo Chemosensitivity Assays for Individualized Cancer Chemotherapy: A Meta-Analysis

Blom, Kristin; Nygren, Peter; Larsson, Rolf; Andersson, Claes R.

Ingår i SLAS TECHNOLOGY, s. 306-314, 2017

• DOI för Predictive Value of Ex Vivo Chemosensitivity Assays for Individualized Cancer Chemotherapy: A Meta-Analysis

Combination screening in vitro identifies synergistically acting KP372-1 and cytarabine against acute myeloid leukemia

Österroos, Albin; Kashif, Muhammad; Haglund, Caroline; Blom, Kristin et al.

Ingår i Biochemical Pharmacology, s. 40-49, 2016

• DOI för Combination screening in vitro identifies synergistically acting KP372-1 and cytarabine against acute myeloid leukemia

Ex Vivo Assessment of Drug Activity in Patient Tumor Cells as a Basis for Tailored Cancer Therapy

Blom, Kristin; Nygren, Peter; Alvarsson, Jonathan; Larsson, Rolf et al.

Ingår i JALA, s. 178-187, 2016

• DOI för Ex Vivo Assessment of Drug Activity in Patient Tumor Cells as a Basis for Tailored Cancer Therapy

The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner

Jönsson, Ulla-Britt; Blom, Kristin; Stålenheim, Gunnemar; Douhan Håkansson, Lena et al.

Ingår i Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), s. 283-291, 2014

• DOI för The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner

Eosinophil associated genes in the inflammatory bowel disease 4 region: Correlation to inflammatory bowel disease revealed

Blom, Kristin; Rubin, Jenny; Halfvarson, Jonas; Torkvist, Leif et al.

Ingår i World Journal of Gastroenterology, s. 6409-6419, 2012

• DOI för Eosinophil associated genes in the inflammatory bowel disease 4 region: Correlation to inflammatory bowel disease revealed

Functional Phenotyping Reveals Treatment-Response Heterogeneity Across Molecular Subtypes of Pediatric BCP-ALL

Enblad, Anna Pia; Krali, Olga; Lundmark, Anders; Lysenkova Wiklander, Mariya et al.