Lena Claesson-Welsh

Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Pal, Sagnik; Su, Yangyang; Nwadozi, Emmanuel; Claesson-Welsh, Lena et al.

Ingår i Angiogenesis, 2025

• DOI för Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
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TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Shan, Ke Zoe; Le, Trieu; Liang, Pengfei; Dong, Ping et al.

Ingår i Journal of Cell Science, 2024

• DOI för TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Hypersensitive blood vessels in Clarkson disease

Nwadozi, Emmanuel; Claesson-Welsh, Lena

Ingår i Journal of Clinical Investigation, 2024

• DOI för Hypersensitive blood vessels in Clarkson disease
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VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis

Sáinz-Jaspeado, Miguel; Ring, Sarah; Proulx, Steven T.; Richards, Mark et al.

Ingår i Life Science Alliance, 2024

• DOI för VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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Report from the 2023 workshop on endothelial permeability, edema and inflammation

Vestweber, Dietmar; Claesson-Welsh, Lena; McDonald, Donald M.; Williams, Timothy et al.

Ingår i Nature Cardiovascular Research, s. 1120-1124, 2023

• DOI för Report from the 2023 workshop on endothelial permeability, edema and inflammation

Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Pal, Sagnik; Su, Yangyang; Nwadozi, Emmanuel; Claesson-Welsh, Lena et al.

Ingår i Angiogenesis, 2025

• DOI för Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
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TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Shan, Ke Zoe; Le, Trieu; Liang, Pengfei; Dong, Ping et al.

Ingår i Journal of Cell Science, 2024

• DOI för TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Hypersensitive blood vessels in Clarkson disease

Nwadozi, Emmanuel; Claesson-Welsh, Lena

Ingår i Journal of Clinical Investigation, 2024

• DOI för Hypersensitive blood vessels in Clarkson disease
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VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis

Sáinz-Jaspeado, Miguel; Ring, Sarah; Proulx, Steven T.; Richards, Mark et al.

Ingår i Life Science Alliance, 2024

• DOI för VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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Report from the 2023 workshop on endothelial permeability, edema and inflammation

Vestweber, Dietmar; Claesson-Welsh, Lena; McDonald, Donald M.; Williams, Timothy et al.

Ingår i Nature Cardiovascular Research, s. 1120-1124, 2023

• DOI för Report from the 2023 workshop on endothelial permeability, edema and inflammation

Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src

Sjöberg, Elin; Melssen, Marit; Richards, Mark; Ding, Yindi et al.

Ingår i Journal of Clinical Investigation, 2023

• DOI för Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src
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Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption

Zarkada, Georgia; Chen, Xun; Zhou, Xuetong; Lange, Martin et al.

Ingår i Circulation Research, s. 333-349, 2023

• DOI för Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption

CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin

Lugano, Roberta; Vemuri, Kalyani; Barbera, Stefano; Orlandini, Maurizio et al.

Ingår i The FASEB Journal, 2023

• DOI för CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin
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Tyrosine-protein kinase Yes is essential in vascular barrier dynamics

Claesson-Welsh, Lena; Jin, Yi

Ingår i Nature Cardiovascular Research, s. 1136-1137, 2022

• DOI för Tyrosine-protein kinase Yes is essential in vascular barrier dynamics

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Ingår i Nature Cardiovascular Research, s. 1156-1173, 2022

• DOI för Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
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Targeting VEGF-induced vascular permeability

Richards, Mark; Claesson-Welsh, Lena

Ingår i Nature Cardiovascular Research, s. 413-414, 2022

• DOI för Targeting VEGF-induced vascular permeability

Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Richards, Mark; Nwadozi, Emmanuel; Pal, Sagnik; Martinsson, Pernilla et al.

Ingår i eLIFE, 2022

• DOI för Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
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Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

Zhou, Weibin; Liu, Keli; Zeng, Lei; He, Jiaqi et al.

Ingår i Circulation, s. 1855-1881, 2022

• DOI för Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

Endothelial Unc5B controls blood-brain barrier integrity

Boye, Kevin; Geraldo, Luiz Henrique; Furtado, Jessica; Pibouin-Fragner, Laurence et al.

Ingår i Nature Communications, 2022

• DOI för Endothelial Unc5B controls blood-brain barrier integrity
• Ladda ner fulltext (pdf) av Endothelial Unc5B controls blood-brain barrier integrity

p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin

Maeso-Alonso, Laura; Alonso-Olivares, Hugo; Martinez-Garcia, Nicole; Lopez-Ferreras, Lorena et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2022

• DOI för p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin
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Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

Persson Skare, Tor; Kaito, Hiroshi; Durall, Claudia; Aastrup, Teodor et al.

Ingår i Cells, 2022

• DOI för Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells
• Ladda ner fulltext (pdf) av Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin alpha 5

Richards, Mark; Pal, Sagnik; Sjöberg, Elin; Martinsson, Pernilla et al.

Ingår i Cell Reports, 2021

• DOI för Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin alpha 5

Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Vion, Anne-Clemence; Perovic, Tijana; Petit, Charlie; Hollfinger, Irene et al.

Ingår i Frontiers in Physiology, 2021

• DOI för Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways
• Ladda ner fulltext (pdf) av Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Sainz-Jaspeado, Miguel; Smith, Ross O.; Plunde, Oscar; Pawelzik, Sven-Christian et al.

Ingår i Circulation, s. 1629-1645, 2021

• DOI för Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium
• Ladda ner fulltext (pdf) av Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis

Nitzsche, Anja; Pietilä, Riikka; Love, Dominic T.; Testini, Chiara et al.

Ingår i EMBO Reports, 2021

• DOI för Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
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eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Ninchoji, Takeshi; Love, Dominic T.; Smith, Ross O.; Hedlund, Marie et al.

Ingår i eLIFE, 2021

• DOI för eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin
• Ladda ner fulltext (pdf) av eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Stories in Molecular Medicine April 2021

Kavelaars, Annemieke; Claesson-Welsh, Lena; Culp-Hill, Rachel; Lothstein, Katherine et al.

Ingår i Trends in Molecular Medicine, s. 293-296, 2021

• DOI för Stories in Molecular Medicine April 2021

Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival

Persson Skare, Tor; Sjöberg, Elin; Berglund, Mattias; Smith, Ross O. et al.

Ingår i eJHaem, s. 199-207, 2020

• DOI för Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival
• Ladda ner fulltext (pdf) av Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival

Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction

Li, Xiujuan; Redfors, Bjorn; Sainz-Jaspeado, Miguel; Shi, Shujing et al.

Ingår i Frontiers in Physiology, 2020

• DOI för Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction
• Ladda ner fulltext (pdf) av Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction

c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly

Schimmel, Lilian; Fukuhara, Daisuke; Richards, Mark; Jin, Yi et al.

Ingår i Development, 2020

• DOI för c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly
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Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma

Morin, Eric; Lindskog, Cecilia; Johansson, Martin; Egevad, Lars et al.

Ingår i Journal of Pathology, s. 387-396, 2020

• DOI för Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma
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How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer: Comment

Claesson-Welsh, Lena

Ingår i Journal of Clinical Investigation, s. 1093-1095, 2020

• DOI för How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer: Comment

Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin

Smith, Ross O.; Ninchoji, Takeshi; Gordon, Emma; Andre, Helder et al.

Ingår i eLIFE, 2020

• DOI för Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
• Ladda ner fulltext (pdf) av Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin

House retinal cell behaviour in space and time using light sheet fluorescence microscopy

Prahst, Claudia; Ashrafzadeh, Parham; Mead, Thomas; Figueiredo, Ana et al.

Ingår i eLIFE, 2020

• DOI för House retinal cell behaviour in space and time using light sheet fluorescence microscopy
• Ladda ner fulltext (pdf) av House retinal cell behaviour in space and time using light sheet fluorescence microscopy

Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

Ragunathrao, Vijay Avin Balaji; Anwar, Mumtaz; Akhter, Md Zahid; Chavez, Alejandra et al.

Ingår i Cell Reports, s. 3472-3487, 2019

• DOI för Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
• Ladda ner fulltext (pdf) av Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

ATTRACT Arterial Flow as Attractor for Endothelial Cell Migration

Georgieva, Petya B.; Marchuk, Douglas A.; Gerhardt, Holger; Franco, Claudio A. et al.

Ingår i Circulation Research, s. 262-264, 2019

• DOI för ATTRACT Arterial Flow as Attractor for Endothelial Cell Migration

What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality

Claesson-Welsh, Lena

Ingår i EMBO Molecular Medicine, 2019

• DOI för What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality
• Ladda ner fulltext (pdf) av What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality

Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Testini, Chiara; Smith, Ross O.; Jin, Yi; Martinsson, Pernilla et al.

Ingår i EMBO Reports, 2019

• DOI för Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2
• Ladda ner fulltext (pdf) av Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pietilä, Ilkka; van Mourik, Djenolan; Tamelander, Andreas; Kriz, Vitezslav et al.

Ingår i Cells, 2019

• DOI för Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB
• Ladda ner fulltext (pdf) av Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Caspase-8 modulates physiological and pathological angiogenesis during retina development

Tisch, Nathalie; Freire-Valls, Aida; Yerbes, Rosario; Paredes, Isidora et al.

Ingår i Journal of Clinical Investigation, s. 5092-5107, 2019

• DOI för Caspase-8 modulates physiological and pathological angiogenesis during retina development

Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

Corada, Monica; Orsenigo, Fabrizio; Bhat, Ganesh Parameshwar; Conze, Lei Liu et al.

Ingår i Circulation Research, s. 511-525, 2019

• DOI för Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier
• Ladda ner fulltext (pdf) av Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Ingår i Acta Oncologica, s. 187-194, 2018

• DOI för U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
• Ladda ner fulltext (pdf) av U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Alk1 (Activin Receptor-Like Kinase 1) and Vascular Hyperpermeability in Diabetic Retinopathy: More Is Less

Claesson-Welsh, Lena

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1673-1675, 2018

• DOI för Alk1 (Activin Receptor-Like Kinase 1) and Vascular Hyperpermeability in Diabetic Retinopathy: More Is Less

Shear stress, notch and VE-cadherin: the molecular mechanism of vascular fusion

Caolo, V.; Peacock, H. M.; Kasaai, B.; Swennen, G. et al.

Ingår i Cardiovascular Research, 2018

Shear Stress and VE-Cadherin: The Molecular Mechanism of Vascular Fusion

Caolo, Vincenza; Peacock, Hanna M.; Kasaai, Bahar; Swennen, Geertje et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2174-2183, 2018

• DOI för Shear Stress and VE-Cadherin: The Molecular Mechanism of Vascular Fusion

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Ingår i Theranostics, s. 4462-4476, 2018

• DOI för Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
• Ladda ner fulltext (pdf) av Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Honkura, Naoki; Richards, Mark; Laviña, Bàrbara; Sainz-Jaspeado, Miguel et al.

Ingår i Nature Communications, 2018

• DOI för Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events
• Ladda ner fulltext (pdf) av Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Morin, Eric; Sjöberg, Elin; Tjomsland, Vegard; Testini, Chiara et al.

Ingår i Journal of Pathology, s. 311-322, 2018

• DOI för VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival
• Ladda ner fulltext (pdf) av VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018

• DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
• Ladda ner fulltext (pdf) av Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan, Narendra; Yan, Junhong; Boge, Annegret; Scrivener, Elaine et al.

Ingår i Scientific Reports, 2017

• DOI för Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation
• Ladda ner fulltext (pdf) av Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model

Mitran, Bogdan; Guler, R.; Roche, Francis P.; Lindström, Elin et al.

Ingår i European Journal of Nuclear Medicine and Molecular Imaging, 2017

Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Ingår i Oncotarget, s. 73200-73215, 2016

• DOI för Case-specific potentiation of glioblastoma drugs by pterostilbene

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Padhan, Narendra; Nordling, Torbjorn E. M.; Sundström, Magnus; Åkerud, Peter et al.

Ingår i BMC Cancer, 2016

• DOI för High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
• Ladda ner fulltext (pdf) av High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Li, Xiujuan; Padhan, Narendra; Sjöström, Elisabet O.; Roche, Francis P. et al.

Ingår i Nature Communications, 2016

• DOI för VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
• Ladda ner fulltext (pdf) av VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Gordon, Emma J.; Fukuhara, Daisuke; Weström, Simone; Padhan, Narendra et al.

Ingår i Science Signaling, 2016

• DOI för The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns

Claesson-Welsh, Lena; Hansson, Goran K.

Ingår i The Lancet, s. 942-942, 2016

• DOI för Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns

Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling

Fleetwood, Filippa; Guler, Rezan; Gordon, Emma; Stahl, Stefan et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 1671-1683, 2016

• DOI för Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling

New Frontiers in VEGF/VEGFR Biology

Claesson-Welsh, Lena

Ingår i Journal of Vascular Research, s. 79-79, 2015

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Ingår i Blood, s. 2016-2026, 2015

• DOI för Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with alpha 2 integrin

Roche, Francis; Sipilä, Kalle; Honjo, Satoshi; Staffan, Johansson et al.

Ingår i Matrix Biology, s. 89-99, 2015

• DOI för Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with alpha 2 integrin

p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGF beta signaling

Fernandez-Alonso, R.; Martin-Lopez, M.; Gonzalez-Cano, L.; Garcia, S. et al.

Ingår i Cell Death and Differentiation, s. 1287-+, 2015

• DOI för p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGF beta signaling

On the physiology of vascular permeability

Claesson-Welsh, Lena

Ingår i Acta Physiologica, s. 19-19, 2015

Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey et al.

Ingår i Circulation Research, s. 806-822, 2014

• DOI för Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet K.; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2014

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

Bentley, Katie; Franco, Claudio Areias; Philippides, Andrew; Blanco, Raquel et al.

Ingår i Nature Cell Biology, s. 309-321, 2014

• DOI för The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

Koch, Sina; van Meeteren, Laurens A.; Morin, Eric; Testini, Chiara et al.

Ingår i Developmental Cell, s. 633-646, 2014

• DOI för NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.

Tugues, Sònia; Roche, Francis; Noguer, Oriol; Orlova, Anna et al.

Ingår i PLOS ONE, 2014

• DOI för Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.
• Ladda ner fulltext (pdf) av Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Hayashi, Makoto; Majumdar, Arindam; Li, Xiujuan; Adler, Jeremy et al.

Ingår i Nature Communications, s. 1672, 2013

• DOI för VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Pulmunary Lymphangiectasia Resulting From Vascular Endotelial Growth Factor-C Overexpression During a Critical Period

Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey et al.

Ingår i Circulation Research, 2013

Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-beta 1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo

Tugues, Sonia; Honjo, Satoshi; König, Christian; Padhan, Narendra et al.

Ingår i Journal of Biological Chemistry, s. 19060-19071, 2013

• DOI för Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-beta 1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo

Introduction to symposium on vascular biology, metabolism and cancer

Claesson-Welsh, Lena

Ingår i Journal of Internal Medicine, s. 112-113, 2013

• DOI för Introduction to symposium on vascular biology, metabolism and cancer

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet; Essand, Magnus; Claesson-Welsh, Lena

Ingår i Molecular Therapy, 2013

Introduction to the ECR special angiogenesis issue

Claesson-Welsh, Lena; Gerhardt, Holger

Ingår i Experimental Cell Research, s. 1239-1239, 2013

• DOI för Introduction to the ECR special angiogenesis issue

The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013

Hypoxia-Induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

Lanner, Fredrik; Lee, Kian Leong; Ortega, German C.; Sohl, Marcus et al.

Ingår i Stem Cells and Development, s. 1360-1369, 2013

• DOI för Hypoxia-Induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

Signal transduction by vascular endothelial growth factor receptors

Koch, Sina; Claesson-Welsh, Lena

Ingår i Cold Spring Harbor Perspectives in Medicine, 2012

• DOI för Signal transduction by vascular endothelial growth factor receptors

Histidine-rich Glycoprotein Regulates Macrophage Differentiation

Noguer, Oriol; Tugues, Sonia; Honjo, Satoshi; Claesson-Welsh, Lena

Ingår i European Journal of Cancer, 2012

• DOI för Histidine-rich Glycoprotein Regulates Macrophage Differentiation

Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Le Jan, Sébastien; Hayashi, Makoto; Kasza, Zsolt; Eriksson, Inger et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1255-1263, 2012

• DOI för Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization

Tugues, Sònia; Honjo, Satoshi; König, Christian; Noguer, Oriol et al.

Ingår i Cancer Research, 2012

• DOI för Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization

Receptor Talk and Tumor Cell Walk in Glioblastoma

Claesson-Welsh, Lena

Ingår i Cancer Cell, s. 1-2, 2012

• DOI för Receptor Talk and Tumor Cell Walk in Glioblastoma

Signal transduction by vascular endothelial growth factor receptors

Claesson-Welsh, Lena

Ingår i Vascular pharmacology, s. 308-308, 2012

• DOI för Signal transduction by vascular endothelial growth factor receptors

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Sun, Zuyue; Li, Xiujuan; Massena, Sara; Kutschera, Simone et al.

Ingår i Journal of Experimental Medicine, s. 1363-1377, 2012

• DOI för VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

Rivera, Corban G.; Mellberg, Sofie; Claesson-Welsh, Lena; Bader, Joel S. et al.

Ingår i PLOS ONE, 2011

• DOI för Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

Rolny, Charlotte; Mazzone, Massimiliano; Tugues, Sònia; Laoui, Damya et al.

Ingår i Cancer Cell, s. 31-44, 2011

• DOI för HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

Van de Veire, Sara; Stalmans, Ingeborg; Heindryckx, Femke; Oura, Hajimu et al.

Ingår i Cell, s. 178-190, 2010

• DOI för Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

Berge, Tone; Sundvold-Gjerstad, Vibeke; Granum, Stine; Andersen, Thorny C. et al.

Ingår i PloS one, 2010

• DOI för T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

VEGF-mediated signal transduction in lymphatic endothelial cells

Bahram, Fuad; Claesson-Welsh, Lena

Ingår i Pathophysiology : the official journal of the International Society for Pathophysiology / ISP, s. 253-261, 2010

• DOI för VEGF-mediated signal transduction in lymphatic endothelial cells

Vascular endothelial growth factor B controls endothelial fatty acid uptake

Hagberg, Carolina E.; Falkevall, Annelie; Wang, Xun; Larsson, Erik et al.

Ingår i Nature, s. 917-921, 2010

• DOI för Vascular endothelial growth factor B controls endothelial fatty acid uptake

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

Nilsson, Ingrid; Bahram, Fuad; Li, Xiujuan; Gualandi, Laura et al.

Ingår i EMBO Journal, s. 1377-1388, 2010

• DOI för VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

Gremlin: vexing VEGF receptor agonist

Claesson-Welsh, Lena

Ingår i Blood, s. 3386-3387, 2010

• DOI för Gremlin: vexing VEGF receptor agonist

p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration

Li, Zhilun; Zhang, Hongquan; Lundin, Lars; Thullberg, Minna et al.

Ingår i Journal of Biological Chemistry, s. 23699-23710, 2010

• DOI för p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

Geretti, Elena; van Meeteren, Laurens A.; Shimizu, Akio; Dudley, Andrew C. et al.

Ingår i Molecular Cancer Research, s. 1063-1073, 2010

• DOI för A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

ADAM-mediated shedding, a new flavor in angiogenesis regulation

Claesson-Welsh, Lena

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2087-2088, 2010

• DOI för ADAM-mediated shedding, a new flavor in angiogenesis regulation

Distinct role of PLC{beta}3 in VEGF-mediated directional migration and vascular sprouting

Bhattacharya, Resham; Kwon, Junhye; Li, Xiujuan; Wang, Enfeng et al.

Ingår i Journal of Cell Science, s. 1025-1034, 2009

• DOI för Distinct role of PLC{beta}3 in VEGF-mediated directional migration and vascular sprouting

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

Mellberg, Sofie; Dimberg, Anna; Bahram, Fuad; Hayashi, Makoto et al.

Ingår i The FASEB Journal, s. 1490-1502, 2009

• DOI för Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

Type 3 cystatins: fetuins, kininogen and histidine-rich glycoprotein

Lee, Chunsik; Bongcam-Rudloff, Erik; Sollner, Christian; Jahnen-Dechent, Willi et al.

Ingår i Frontiers in Bioscience, s. 2911-2922, 2009

• DOI för Type 3 cystatins: fetuins, kininogen and histidine-rich glycoprotein

Vascular basement membrane components in angiogenesis: an act of balance

Jakobsson, Lars; Claesson-Welsh, Lena

Ingår i Scientific World Journal, s. 1246-1249, 2008

• DOI för Vascular basement membrane components in angiogenesis: an act of balance

Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow

Jakobsson, Lars; Domogatskaya, Anna; Tryggvason, Karl; Edgar, David et al.

Ingår i The FASEB Journal, s. 1530-1539, 2008

• DOI för Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow

alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis

Dimberg, Anna; Rylova, Svetlana; Dieterich, Lothar C; Olsson, Anna-Karin et al.

Ingår i Blood, s. 2015-2023, 2008

• DOI för alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

Kawamura, Harukiyo; Li, Xiujuan; Goishi, Katsutoshi; van Meeteren, Laurens A et al.

Ingår i Blood, s. 3638-49, 2008

• DOI för Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

Ninein Is Expressed in the Cytoplasm of Angiogenic Tip-Cells and Regulates Tubular Morphogenesis of Endothelial Cells

Matsumoto, Taro; Schiller, Petter; Dietrich, Lothar C.; Bahram, Fuad et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2123-2130, 2008

• DOI för Ninein Is Expressed in the Cytoplasm of Angiogenic Tip-Cells and Regulates Tubular Morphogenesis of Endothelial Cells

Healing hemangiomas

Claesson-Welsh, Lena

Ingår i Nature Medicine, s. 1147-8, 2008

• DOI för Healing hemangiomas

Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR

Cébe-Suarez, Stéphanie; Grünewald, Felix S.; Jaussi, Rolf; Li, Xiujuan et al.

Ingår i The FASEB Journal, s. 3078-3086, 2008

• DOI för Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR

Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

Kawamura, Harukiyo; Li, Xiujuan; Harper, Steven J; Bates, David O et al.

Ingår i Cancer Research, s. 4683-4692, 2008

• DOI för Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

VEGF-B taken to our hearts: specific effect of VEGF-B in myocardial ischemia

Claesson-Welsh, Lena

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1575-6, 2008

• DOI för VEGF-B taken to our hearts: specific effect of VEGF-B in myocardial ischemia

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors

Li, Xiujuan; Edholm, Dan; Lanner, Fredrik; Breier, Georg et al.

Ingår i Stem Cells, s. 2987-2995, 2007

• DOI för Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors

Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro

Magnusson, Peetra U.; Looman, Camilla; Åhgren, Aive; Wu, Yan et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 2142-2149, 2007

• DOI för Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Magnusson, Peetra U; Dimberg, Anna; Mellberg, Sofie; Lukinius, Agneta et al.

Ingår i Blood, s. 4214-4222, 2007

• DOI för FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Angiomotin regulates endothelial cell migration during embryonic angiogenesis

Aase, Karin; Ernkvist, Mira; Ebarasi, Lwaki; Jakobsson, Lars et al.

Ingår i Genes & Development, s. 2055-2068, 2007

• DOI för Angiomotin regulates endothelial cell migration during embryonic angiogenesis

Early lymph vessel development from embryonic stem cells

Kreuger, Johan; Nilsson, Ingrid; Kerjaschki, Dontscho; Petrova, Tatiana et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 1073-1078, 2006

• DOI för Early lymph vessel development from embryonic stem cells

Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein

Dixelius, Johan; Olsson, Anna-Karin; Thulin, Åsa; Lee, Chunsik et al.

Ingår i Cancer Research, s. 2089-97, 2006

• DOI för Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein

Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions

Lee, Chunsik; Dixelius, Johan; Thulin, Åsa; Kawamura, Harukiyo et al.

Ingår i Experimental Cell Research, s. 2547-2556, 2006

• DOI för Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Rolny, Charlotte; Nilsson, Ingrid; Magnusson, Peetra; Armulik, Annika et al.

Ingår i Blood, s. 1877-1886, 2006

• DOI för Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

VEGF receptor signalling: in control of vascular function

Olsson, Anna-Karin; Dimberg, Anna; Kreuger, Johan; Claesson-Welsh, Lena

Ingår i Nature reviews. Molecular cell biology, s. 359-371, 2006

• DOI för VEGF receptor signalling: in control of vascular function

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis

Jakobsson, Lars; Kreuger, Johan; Holmborn, Katarina; Lundin, Lars et al.

Ingår i Developmental Cell, s. 625-634, 2006

Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Magnusson, Peetra Ulrica; Ronca, Roberto; Dell'Era, Patrizia; Carlstedt, Pia et al.

Ingår i Arteriosclerosis, Thrombosis and Vascular Biology, s. 944-949, 2005

• DOI för Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.

Matsumoto, Taro; Bohman, Svante; Dixelius, Johan; Berge, Tone et al.

Ingår i EMBO J, s. 2342-53, 2005

Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis.

Bohman, Svante; Matsumoto, Taro; Suh, Kwang; Dimberg, Anna et al.

Ingår i J Biol Chem, s. 42397-404, 2005

Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development

Nilsson, Ingrid; Rolny, Charlotte; Wu, Yan; Pytowski, Bronislaw et al.

Ingår i The FASEB Journal, s. 1507-15, 2004

• DOI för Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development

Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

Magnusson, Peetra; Rolny, Charlotte; Jakobsson, Lars; Wikner, Charlotte et al.

Ingår i Journal of Cell Science, s. 1513-1523, 2004

• DOI för Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization

Olsson, Anna-Karin; Johansson, Irja; Åkerud, Helena; Einarsson, Barbro et al.

Ingår i Cancer Research, s. 9012-9017, 2004

• DOI för The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization

A fragment of histidine-rich glycoprotein is a potent inhibitor of tumor vascularization

Olsson, Anna-Karin; Larsson, Helena; Dixelius, Johan; Johansson, Irja et al.

Ingår i Cancer Research, s. 599-605, 2004

Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1.

Klint, Peter; Hellman, Ulf; Wernstedt, Christer; Aman, Pierre et al.

Ingår i Cell Signal, s. 515-20, 2004

Angiogenesis in Synergy with Fibroblast Growth Factor by Distinct Regulation of the Gene and Protein. Expression Profile in Endothelial Cells.

Dixelius, J; Jakobsson, L; Genersch, E; Bohman, S et al.

Ingår i J Biol Chem, s. 23766, 2004

The adaptor protein Shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

Holmqvist, Kristina; Cross, Michael J; Rolny, Charlotte; Hägerkvist, Robert et al.

Ingår i J Biological chemistry, s. 22267-22275, 2004

Endostatin action and intracellular signaling: beta-catenin as a potential target?

Dixelius, J; Cross, MJ; Matsumoto, T; Claesson-Welsh, L

Ingår i Cancer Letters, s. 1, 2003

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

Dixelius, Johan; Mäkinen, Taija; Wirzenius, Maria; Karkkainen, Marika J. et al.

Ingår i J Biol Chem, s. 40973, 2003

Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin.

Lundin, Lars; Rönnstrand, Lars; Cross, Michael; Hellberg, Carina et al.

Ingår i Exp Cell Res, s. 190-8, 2003

A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2.

Qi, JH; Ebrahem, Q; Moore, N; Murphy, G et al.

Ingår i Nat Med., s. 407, 2003

[Islet of Langerhans transplantation in type I diabetes. Regulation of neovascularization in the transplant is a key question]

Claesson-Welsh, L

Ingår i Lakartidningen, s. 1210, 2003

VEGF-receptor signal transduction

Cross, MJ; Dixelius, J; Matsumoto, T; Claesson-Welsh, L

Ingår i Trends Biochem Sci, s. 488, 2003

Signal transduction by vascular endothelial growth factor receptors.

Claesson-Welsh, L

Ingår i Biochem Soc Trans, s. 20, 2003

Angiostatin and endostatin inhibit endothelial cell migration in response to FGF and VEGF without interfering with specific intracellular signal transduction pathways.

Eriksson, K; Magnusson, P; Dixelius, J; Claesson-Welsh, L et al.

Ingår i FEBS Lett., s. 19, 2003

p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis

Matsumoto, Taro; Turesson, Ingela; Book, Majlis; Gerwins, Pär et al.

Ingår i Journal of Cell Biology, s. 149-160, 2002

• DOI för p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis

The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Cross, Michael J; Lu, Lingge; Magnusson, Peetra; Nyqvist, Daniel et al.

Ingår i Molecular Biology of the Cell, s. 2881-2893, 2002

• DOI för The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Angiogeneshämmare sannolikt komplement vid cancerbehandlingar

Christofferson, R; Claesson-Welsh, L; Muhr, C

Ingår i Läkartidningen, s. 4138, 2002

Heparin amplifies platelet-derived growth factor (PDGF)- BB-induced PDGFalpha -receptor but not PDGF beta -receptor tyrosine phosphorylation inheparan sulfate-deficient cells. Effects on signal transduction andbiological responses.

Rolny, C; Spillmann, D; Lindahl, U; Claesson-Welsh, L

Ingår i J Biol Chem, s. 19315, 2002

Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis

Dixelius, Johan; Larsson, Helena; Sasaki, Takako; Holmqvist, Kristina et al.

Ingår i Blood, s. 3403-3411, 2000

Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Hooshmand-Rad, Roya; Lu, Lingge; Heldin, Carl-Henrik; Claesson-Welsh, Lena et al.

Ingår i Experimental Cell Research, s. 245-254, 2000

• DOI för Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

Heuchel, Rainer; Berg, Ansgar; Tallquist, Michelle; Åhlén, Karina et al.

Ingår i Proc Natl Acad Sci U S A, s. 11410-5, 1999

Phosphoinositide 3 kinase is critical for survival, mitogenesis and migration but not for differentiation of endothelial cells.

Qi, J H; Matsumoto, T; Huang, K; Olausson, K et al.

Ingår i Angiogenesis, s. 371-80, 1999

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD

Claesson-Welsh, Lena; Welsh, Michael; Ito, Nobuyuki; Anand-Apte, Bela et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 5579-5583, 1998

Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-g and migration of Flt 1 expressing cells.

Landgren, Eva; Schiller, Petter; Cao, Yihai; Claesson-Welsh, Lena

Ingår i Oncogene, s. 359, 1998

Phosphorylation of a 72-kDa protein in PDGF-stimulated cells which forms complex with c-Crk, c-Fyn and Eps15.

Hansen, Klaus; Rönnstrand, Lars; Claesson-Welsh, Lena; Heldin, Carl-Henrik

Ingår i FEBS Letters, s. 195, 1997

Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins

Karlsson, Torbjörn; Songyang, Z; Landgren, E; Lavergne, C et al.

Ingår i Oncogene, s. 1475-1483, 1995

A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a heterodimeric receptor complex

Rupp, Eva; Siegbahn, Agneta; Rönnstrand, Lars; Wernstedt, Christer et al.

Ingår i European Journal of Biochemistry, s. 29-41, 1994

Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Heldin, Carl-Henrik; Östman, Arne; Eriksson, Anders; Siegbahn, Agneta et al.

Ingår i Kidney International, s. 571-574, 1992

• DOI för Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

Blume-Jensen, Peter; Claesson-Welsh, Lena; Siegbahn, Agneta; Zsebo, Krisztina M. et al.

Ingår i EMBO Journal, s. 4121-4128, 1991

Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

Claesson-Welsh, Lena; Dejana, Elisabetta; McDonald, Donald M.

Ingår i Trends in Molecular Medicine, s. 314-331, 2021

• DOI för Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies
• Ladda ner fulltext (pdf) av Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer

Claesson-Welsh, Lena

Ingår i Upsala Journal of Medical Sciences, s. 205-210, 2020

• DOI för Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer
• Ladda ner fulltext (pdf) av Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer

Cytokines regulating lymphangiogenesis

Sainz-Jaspeado, Miguel; Claesson-Welsh, Lena

Ingår i Current Opinion in Immunology, s. 58-63, 2018

• DOI för Cytokines regulating lymphangiogenesis

Mechanisms and regulation of endothelial VEGF receptor signalling

Simons, Michael; Gordon, Emma; Claesson-Welsh, Lena

Ingår i Nature reviews. Molecular cell biology, s. 611-625, 2016

• DOI för Mechanisms and regulation of endothelial VEGF receptor signalling

VEGF receptor signal transduction - A brief update

Claesson-Welsh, Lena

Ingår i Vascular pharmacology, s. 14-17, 2016

• DOI för VEGF receptor signal transduction - A brief update

Vascular permeability - the essentials

Claesson-Welsh, Lena

Ingår i Upsala Journal of Medical Sciences, s. 135-143, 2015

• DOI för Vascular permeability - the essentials

VEGFA and tumour angiogenesis

Claesson-Welsh, Lena; Welsh, Michael

Ingår i Journal of Internal Medicine, s. 114-127, 2013

• DOI för VEGFA and tumour angiogenesis
• Ladda ner fulltext (pdf) av VEGFA and tumour angiogenesis

Blood vessels as targets in tumor therapy

Claesson-Welsh, Lena

Ingår i Upsala Journal of Medical Sciences, s. 178-186, 2012

• DOI för Blood vessels as targets in tumor therapy

Signal transduction by vascular endothelial growth factor receptors

Koch, Sina; Tugues, Sonia; Li, Xiujuan; Gualandi, Laura et al.

Ingår i Biochemical Journal, s. 169-183, 2011

• DOI för Signal transduction by vascular endothelial growth factor receptors

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

Tugues, Sonia; Koch, Sina; Gualandi, Laura; Li, Xiujuan et al.

Ingår i Molecular Aspects of Medicine, s. 88-111, 2011

• DOI för Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

Embryonic stem cell models in vascular biology

Li, Xiujuan; Claesson-Welsh, Lena

Ingår i Journal of Thrombosis and Haemostasis, s. 53-56, 2009

• DOI för Embryonic stem cell models in vascular biology

Building blood vessels- Stem cell models in vascular biology

Jakobsson, Lars; Kreuger, Johan; Claesson-Welsh, Lena

Ingår i Journal of Cell Biology, s. 751-755, 2007

• DOI för Building blood vessels- Stem cell models in vascular biology

Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis.

Shibuya, Masabumi; Claesson-Welsh, Lena

Ingår i Exp Cell Res, s. 549-60, 2006

VEGF receptor signal transduction

Li, Xiujuan; Claesson-Welsh, Lena; Shibuya, Masabumi

Ingår i Angiogenesis, s. 261-284, Elsevier, 2008

• DOI för VEGF receptor signal transduction

Identification of Biomarkers and Signatures in Protein Data

Nordling, Torbjörn E. M.; Padhan, Narendra; Nelander, Sven; Claesson-Welsh, Lena

Ingår i 2015 IEEE 11Th International Conference On E-Science, s. 411-419, 2015

• DOI för Identification of Biomarkers and Signatures in Protein Data

Enhancing therapeutic effects of radio-immunotherapy using the novel stapled MDM2/X-p53 antagonist PM2

Mortensen, Anja C.; Morin, Eric; Brown, Christopher J; Claesson-Welsh, Lena et al.

Endothelial-specific phosphatase VEPTP negatively regulates VEGF receptor-2 activity

Pal, Sagnik; Oliveira, Filipa; Su, Yangyang; Olsen, Signe et al.