Jin-ping Li

Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid

Wu, Yiyang; Chen, Yujuan; Zhao, Siran; Wan, Jinyu et al.

Ingår i Synthetic and systems biotechnology, s. 437-446, 2026

• DOI för Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid
• Ladda ner fulltext (pdf) av Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid

Streptomyces: boost chassis strains for production of invaluable natural products

Chen, Simin; Ling, Siqi; Li, Jinpin; Liu, Zhiyan et al.

Ingår i SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, s. 515-535, 2026

• DOI för Streptomyces: boost chassis strains for production of invaluable natural products
• Ladda ner fulltext (pdf) av Streptomyces: boost chassis strains for production of invaluable natural products

Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis

Hu, Binhong; Yao, Ling; Deng, Xin; Zhao, Wei et al.

Ingår i Frontiers in Nutrition, 2026

• DOI för Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis
• Ladda ner fulltext (pdf) av Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis

Structure-Function Relationships of Heparan Sulfate-Based Neoproteoglycans as Selective Immunostimulatory Scaffolds

Chandra, Ankita; Maccarana, Marco; Vishweshwara, Sharath S.; Mardhekar, Sandhya et al.

Ingår i Chemistry - A European Journal, 2025

• DOI för Structure-Function Relationships of Heparan Sulfate-Based Neoproteoglycans as Selective Immunostimulatory Scaffolds

Spatially Decoupled Electro-Biosystem for Efficient CO2-to-Chemicals Conversion via Tandem Catalysis

Han, Lin; Li, Yan; Wang, Xuyuan; Yao, Zhibo et al.

Ingår i Advanced Energy Materials, 2025

• DOI för Spatially Decoupled Electro-Biosystem for Efficient CO2-to-Chemicals Conversion via Tandem Catalysis

Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid

Wu, Yiyang; Chen, Yujuan; Zhao, Siran; Wan, Jinyu et al.

Ingår i Synthetic and systems biotechnology, s. 437-446, 2026

• DOI för Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid
• Ladda ner fulltext (pdf) av Structure characterization assists rational design of polyethyleneglycol diglycidyl ether (PEGDE) substituted hyaluronic acid

Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis

Hu, Binhong; Yao, Ling; Deng, Xin; Zhao, Wei et al.

Ingår i Frontiers in Nutrition, 2026

• DOI för Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis
• Ladda ner fulltext (pdf) av Dendrobium officinale polysaccharide ameliorates high-fat diet-induced hepatic lipid metabolic disorder via the SIRT6/PGC-1α signaling axis

Structure-Function Relationships of Heparan Sulfate-Based Neoproteoglycans as Selective Immunostimulatory Scaffolds

Chandra, Ankita; Maccarana, Marco; Vishweshwara, Sharath S.; Mardhekar, Sandhya et al.

Ingår i Chemistry - A European Journal, 2025

• DOI för Structure-Function Relationships of Heparan Sulfate-Based Neoproteoglycans as Selective Immunostimulatory Scaffolds

Spatially Decoupled Electro-Biosystem for Efficient CO2-to-Chemicals Conversion via Tandem Catalysis

Han, Lin; Li, Yan; Wang, Xuyuan; Yao, Zhibo et al.

Ingår i Advanced Energy Materials, 2025

• DOI för Spatially Decoupled Electro-Biosystem for Efficient CO2-to-Chemicals Conversion via Tandem Catalysis

CpG-A induces liquid-liquid phase separation of HMGB1 to activate the RAGE-mediated inflammatory pathway

Peng, Kaihui; Fu, Gaohong; Chen, Long; Xie, Jiazhi et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2025

• DOI för CpG-A induces liquid-liquid phase separation of HMGB1 to activate the RAGE-mediated inflammatory pathway
• Ladda ner fulltext (pdf) av CpG-A induces liquid-liquid phase separation of HMGB1 to activate the RAGE-mediated inflammatory pathway

De Novo Sequencing of Enoxaparin Oligosaccharides through HILIC-Q-cIM-MS: A Strategy for Resolving Complex Glycans

Zhao, Siran; Yang, Xuexin; Cao, Hui; Li, Ming et al.

Ingår i Analytical Chemistry, s. 15706-15716, 2025

• DOI för De Novo Sequencing of Enoxaparin Oligosaccharides through HILIC-Q-cIM-MS: A Strategy for Resolving Complex Glycans

A Novel Series of Synthetic Heparin-Mimetics-Itaconic Acid-Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis

Nekipelov, Katrin; Al Nahain, Abdullah; Otto, Sven; Xu, Yongbin et al.

Ingår i Macromolecular Bioscience, 2025

• DOI för A Novel Series of Synthetic Heparin-Mimetics-Itaconic Acid-Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis
• Ladda ner fulltext (pdf) av A Novel Series of Synthetic Heparin-Mimetics-Itaconic Acid-Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis

The deficiency of chymase mast cell protease 4 exacerbates dextran sulfate sodium salt-induced colitis in mice and is associated with altered microbiota and metabolome profiles

Li, Zhiqiang; Kuang, Xiaoyuan; Mo, Dashuang; Åbrink, Magnus et al.

Ingår i Frontiers in Cellular and Infection Microbiology, 2025

• DOI för The deficiency of chymase mast cell protease 4 exacerbates dextran sulfate sodium salt-induced colitis in mice and is associated with altered microbiota and metabolome profiles
• Ladda ner fulltext (pdf) av The deficiency of chymase mast cell protease 4 exacerbates dextran sulfate sodium salt-induced colitis in mice and is associated with altered microbiota and metabolome profiles

Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium

Wu, Ruoxuan; Zhang, Tianji; Zhao, Siran; Maccarana, Marco et al.

Ingår i Frontiers in Bioengineering and Biotechnology, 2025

• DOI för Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium
• Ladda ner fulltext (pdf) av Design, synthesis, and anti-inflammatory potential of PROTAC drug molecules based on fondaparinux sodium

GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Netsyk, Olga; Korol, Sergiy V; Li, Jin-ping; Birnir, Bryndis et al.

Ingår i Journal of Alzheimer's Disease, s. 420-428, 2025

• DOI för GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

Dual roles of exostosin glycosyltransferase 1 in Zika virus infection

Ling, Jiaxin; Khan, Asifa; Denkewitz, Matthias; Maccarana, Marco et al.

Ingår i Virulence, 2025

• DOI för Dual roles of exostosin glycosyltransferase 1 in Zika virus infection
• Ladda ner fulltext (pdf) av Dual roles of exostosin glycosyltransferase 1 in Zika virus infection

A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation

Ling, Jiaxin; Lundkvist, Åke; Guerrini, Marco; Ferro, Vito et al.

Ingår i Advanced Science, 2024

• DOI för A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation
• Ladda ner fulltext (pdf) av A Heparan Sulfate Mimetic RAFT Copolymer Inhibits SARS‐CoV‐2 Infection and Ameliorates Viral‐Induced Inflammation

Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses

Nahain, Abdullah Al; Li, Jinlin; Modhiran, Naphak; Watterson, Daniel et al.

Ingår i ACS Applied Bio Materials, s. 2862-2871, 2024

• DOI för Antiviral Activities of Heparan Sulfate Mimetic RAFT Polymers Against Mosquito-borne Viruses

Overview of the current procedures in synthesis of heparin saccharides

Zhao, Siran; Zhang, Tianji; Kan, Ying; Li, Hongmei et al.

Ingår i Carbohydrate Polymers, 2024

• DOI för Overview of the current procedures in synthesis of heparin saccharides
• Ladda ner fulltext (pdf) av Overview of the current procedures in synthesis of heparin saccharides

Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

Yu, Xiaolin; Hu, Wenrui; Dong, Hang; Zhao, Tian et al.

Ingår i Biomacromolecules, s. 4374-4383, 2024

• DOI för Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

Epigenetic Targeting of Heparan Sulfate 3-O- and 6-O-Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities

Bückreiß, Nico; Schulz-Fincke, Marie; König, Philipp; Maccarana, Marco et al.

Ingår i ACS Pharmacology & Translational Science, s. 2484-2495, 2024

• DOI för Epigenetic Targeting of Heparan Sulfate 3-O- and 6-O-Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities

Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity

Yu, Xiaolin; Duan, Guangfei; Pei, Pengfei; Chen, Long et al.

Ingår i eLIFE, 2024

• DOI för Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity
• Ladda ner fulltext (pdf) av Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue

Martinez, Hunter A.; Koliesnik, Ievgen; Kaber, Gernot; Reid, Jacqueline K. et al.

Ingår i Nature Communications, 2024

• DOI för Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
• Ladda ner fulltext (pdf) av Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue

Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts

Maccarana, Marco; Li, Binjie; Li, Honglian; Fang, Jianping et al.

Ingår i Glycobiology, 2024

• DOI för Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts
• Ladda ner fulltext (pdf) av Inhibitors of dermatan sulfate epimerase 1 decreased accumulation of glycosaminoglycans in mucopolysaccharidosis type I fibroblasts

A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis

Li, Li; Barash, Uri; Ilan, Neta; Farhoud, Malik et al.

Ingår i Cells, 2024

• DOI för A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis
• Ladda ner fulltext (pdf) av A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis

Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?

Veraldi, Noemi; Quadri, Isabelle Dentand; van de Looij, Yohan; Modernell, Laura Malaguti et al.

Ingår i Carbohydrate Polymers, 2023

• DOI för Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?
• Ladda ner fulltext (pdf) av Low-molecular weight sulfated marine polysaccharides: Promising molecules to prevent neurodegeneration in mucopolysaccharidosis IIIA?

Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase

Doherty, Gareth G.; Ler, Geraldine Jia Ming; Wimmer, Norbert; Bernhardt, Paul V. et al.

Ingår i ChemBioChem, 2023

• DOI för Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase
• Ladda ner fulltext (pdf) av Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase

Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening

Li, Binjie; Zhang, Tianji; Cao, Hui; Ferro, Vito et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening
• Ladda ner fulltext (pdf) av Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening

Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Zhang, Tianji; Yu, Mingjia; Li, Honglian; Maccarana, Marco et al.

Ingår i Carbohydrate Polymers, 2023

• DOI för Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Heparanase Modulates Chromatin Accessibility

Li, Honglian; Zhang, Hua; Wenz, Amelie S.; Kang, Ziqi et al.

Ingår i Cells, 2023

• DOI för Heparanase Modulates Chromatin Accessibility
• Ladda ner fulltext (pdf) av Heparanase Modulates Chromatin Accessibility

In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels

Zhang, Tianji; Zhao, Siran; Chen, Yujuan; Wang, Jiandong et al.

Ingår i Carbohydrate Polymers, 2023

• DOI för In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels
• Ladda ner fulltext (pdf) av In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels

Antiviral Disaccharide Lead Compounds against SARS-CoV-2 through Computer-Aided High-Throughput Screen

Li, Binjie; Zhang, Tianji; Li, Jin-Ping; Yu, Ming-Jia

Ingår i ChemBioChem, 2022

• DOI för Antiviral Disaccharide Lead Compounds against SARS-CoV-2 through Computer-Aided High-Throughput Screen

Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model

Xiaowen, Cheng; Jia, Juan; Zhang, Tianji; Zhang, Xiao et al.

Ingår i Cells, 2022

• DOI för Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model
• Ladda ner fulltext (pdf) av Heparanase Expression Propagates Liver Damage in CCL4-Induced Mouse Model

Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells

Maccarana, Marco; Jia, Juan; Li, Honglian; Zhang, Xiao et al.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells
• Ladda ner fulltext (pdf) av Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells

GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer

Su, Linjia; Sun, Zhe; Qi, Fangzheng; Su, Huishan et al.

Ingår i Journal of Nanobiotechnology, 2022

• DOI för GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer
• Ladda ner fulltext (pdf) av GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer

Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate

Xue, Song; Zhou, Fan; Zhao, Tian; Zhao, Huimin et al.

Ingår i Nature Communications, 2022

• DOI för Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate
• Ladda ner fulltext (pdf) av Phase separation on cell surface facilitates bFGF signal transduction with heparan sulphate

Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

Gockel, Lukas M.; Heyes, Martin; Li, Honglian; Al Nahain, Abdullah et al.

Ingår i ACS Applied Materials and Interfaces, s. 7080-7093, 2021

• DOI för Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling

Yu, Mingjia; Zhang, Tianji; Li, Jin-Ping; Tan, Yingxia

Ingår i ChemistryOpen, s. 966-975, 2021

• DOI för Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling
• Ladda ner fulltext (pdf) av Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling

Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease

Hammoud, Hayma; Netsyk, Olga; Tafreshiha, Atieh S.; Korol, Sergiy V. et al.

Ingår i Acta Physiologica, 2021

• DOI för Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease
• Ladda ner fulltext (pdf) av Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age-dependent manner, normalizes GABA-activated currents in the tg-APPSwe mouse model of Alzheimer's disease

Dichotomic role of heparanase in a murine model of metabolic syndrome

Hermano, Esther; Carlotti, Francoise; Abecassis, Alexia; Meirovitz, Amichay et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), s. 2771-2780, 2021

• DOI för Dichotomic role of heparanase in a murine model of metabolic syndrome

Glucuronyl C5-epimerase is crucial for epithelial cell maturation during embryonic lung development

Cui, Hao; Xiaowen, Cheng; Batool, Tahira; Zhang, Xiao et al.

Ingår i Glycobiology, s. 223-230, 2021

• DOI för Glucuronyl C5-epimerase is crucial for epithelial cell maturation during embryonic lung development

Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase

Cui, Hao; Wang, Zhaoguang; Zhang, Tianji; Li, Jin-Ping et al.

Ingår i Glycobiology, s. 1018-1025, 2021

• DOI för Re-expression of glucuronyl C5-epimerase in the mutant MEF cells increases heparan sulfate epimerization but has no influence on the Golgi localization and enzymatic activity of 2-O-sulfotransferase

Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts

Maccarana, Marco; Tykesson, Emil; Pera, Edgar M.; Gouignard, Nadege et al.

Ingår i Glycobiology, s. 1319-1329, 2021

• DOI för Inhibition of iduronic acid biosynthesis by ebselen reduces glycosaminoglycan accumulation in mucopolysaccharidosis type I fibroblasts

Reply to Collins et al

Dong, Yi-Min; Sun, Jia; Aude Andrée, Bengobesse Biyoche; Chen, Qian et al.

Ingår i Clinical Infectious Diseases, s. 558-559, 2021

• DOI för Reply to Collins et al

Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease

Zhang, Xiao; O'Callaghan, Paul; Li, Honglian; Tan, Ying-Xia et al.

Ingår i Acta neuropathologica communications, 2021

• DOI för Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease
• Ladda ner fulltext (pdf) av Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease

Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium

Van Bergen, Tine; Etienne, Isabelle; Jia, Juan; Li, Jin-Ping et al.

Ingår i Current Eye Research, s. 1166-1170, 2021

• DOI för Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium

Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival

Agelidis, Alex; Turturice, Benjamin A.; Suryawanshi, Rahul K.; Yadavalli, Tejabhiram et al.

Ingår i JCI Insight, 2021

• DOI för Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival
• Ladda ner fulltext (pdf) av Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival

Development and Validation of a Nomogram for Assessing Survival in Patients With COVID-19 Pneumonia

Dong, Yi-Min; Sun, Jia; Li, Yi-Xin; Chen, Qian et al.

Ingår i Clinical Infectious Diseases, s. 652-660, 2021

• DOI för Development and Validation of a Nomogram for Assessing Survival in Patients With COVID-19 Pneumonia

Diagnostic performance of initial blood urea nitrogen combined with D-dimer levels for predicting in-hospital mortality in COVID-19 patients

Cheng, Anying; Hu, Liu; Wang, Yiru; Huang, Luyan et al.

Ingår i International Journal of Antimicrobial Agents, 2020

• DOI för Diagnostic performance of initial blood urea nitrogen combined with D-dimer levels for predicting in-hospital mortality in COVID-19 patients

Heparin: An old drug with multiple potential targets in Covid-19 therapy

Lindahl, Ulf; Li, Jin-Ping

Ingår i Journal of Thrombosis and Haemostasis, s. 2422-2424, 2020

• DOI för Heparin: An old drug with multiple potential targets in Covid-19 therapy

Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway

Wan, Lu Ming; Zhang, Shi Kun; Li, Su Bo; Li, Wen et al.

Ingår i Thrombosis and Haemostasis, s. 647-657, 2020

• DOI för Heparanase Facilitates PMA-Induced Megakaryocytic Differentiation in K562 Cells via Interleukin 6/STAT3 Pathway

The Potential of Low Molecular Weight Heparin to Mitigate Cytokine Storm in Severe COVID-19 Patients: A Retrospective Cohort Study

Shi, Chen; Wang, Cong; Wang, Hanxiang; Yang, Chao et al.

Ingår i Clinical and Translational Science, s. 1087-1095, 2020

• DOI för The Potential of Low Molecular Weight Heparin to Mitigate Cytokine Storm in Severe COVID-19 Patients: A Retrospective Cohort Study
• Ladda ner fulltext (pdf) av The Potential of Low Molecular Weight Heparin to Mitigate Cytokine Storm in Severe COVID-19 Patients: A Retrospective Cohort Study

Characterization of anti-BCG benz[α]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomycete Nocardia sp. XJ31

Zhang, Li; Zhang, Jingyu; Ren, Biao; Lu, Wanying et al.

Ingår i Applied Microbiology and Biotechnology, s. 8267-8278, 2020

• DOI för Characterization of anti-BCG benz[α]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomycete Nocardia sp. XJ31

Significance of host heparanase in promoting tumor growth and metastasis

Zhang, Gan-Lin; Gutter-Kapon, Lilach; Ilan, Neta; Batool, Tahira et al.

Ingår i Matrix Biology, s. 25-42, 2020

• DOI för Significance of host heparanase in promoting tumor growth and metastasis

Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis

Yang, Wen-Jing; Zhang, Gan-Lin; Cao, Ke-Xin; Liu, Xiao-Ni et al.

Ingår i International Journal of Oncology, s. 890-904, 2020

• DOI för Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis
• Ladda ner fulltext (pdf) av Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis

Implications of Heparan Sulfate and Heparanase in Amyloid Diseases

Li, Jin-Ping; Zhang, Xiao

Ingår i Advances in Experimental Medicine and Biology, s. 631-645, 2020

• DOI för Implications of Heparan Sulfate and Heparanase in Amyloid Diseases

Oligosaccharides mapping of nitrous acid degraded heparin through UHPLC-HILIC/WAX-MS

Zhang, Tianji; Xie, Shaoshuai; Wang, Zhangjie; Zhang, Rui et al.

Ingår i Carbohydrate Polymers, 2020

• DOI för Oligosaccharides mapping of nitrous acid degraded heparin through UHPLC-HILIC/WAX-MS

High-throughput screening identified mitoxantrone to induce death of hepatocellular carcinoma cells with autophagy involvement

Xie, Bushan; He, Xingxing; Guo, Guihai; Zhang, Xiao et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 232-237, 2020

• DOI för High-throughput screening identified mitoxantrone to induce death of hepatocellular carcinoma cells with autophagy involvement

Establishment and characterization of Drosophila cell lines mutant for heparan sulfate modifying enzymes

Nakato, Eriko; Liu, Xin; Eriksson, Inger; Yamamoto, Maki et al.

Ingår i Glycobiology, s. 479-489, 2019

• DOI för Establishment and characterization of Drosophila cell lines mutant for heparan sulfate modifying enzymes

Systemic LPS-induced A beta-solubilization and clearance in A beta PP-transgenic mice is diminished by heparanase overexpression

Jendresen, Charlotte; Digre, Andreas; Cui, Hao; Zhang, Xiao et al.

Ingår i Scientific Reports, 2019

• DOI för Systemic LPS-induced A beta-solubilization and clearance in A beta PP-transgenic mice is diminished by heparanase overexpression
• Ladda ner fulltext (pdf) av Systemic LPS-induced A beta-solubilization and clearance in A beta PP-transgenic mice is diminished by heparanase overexpression

Heparanase Accelerates Obesity-Associated Breast Cancer Progression

Hermano, Esther; Goldberg, Rachel; Rubinstein, Ariel M.; Sonnenblick, Amir et al.

Ingår i Cancer Research, s. 5342-5354, 2019

• DOI för Heparanase Accelerates Obesity-Associated Breast Cancer Progression

Dual roles of heparanase in human carotid plaque calcification

Aldi, Silvia; Eriksson, Linnea; Kronqvist, Malin; Lengquist, Mariette et al.

Ingår i Atherosclerosis, s. 127-136, 2019

• DOI för Dual roles of heparanase in human carotid plaque calcification

Is host heparanase required for the rapid spread of heparan sulfate binding viruses?

Khanna, Mayank; Ranasinghe, Charani; Browne, Anna M.; Li, Jin-Ping et al.

Ingår i Virology, s. 1-6, 2019

• DOI för Is host heparanase required for the rapid spread of heparan sulfate binding viruses?

Heparan sulfate proteoglycan - A common receptor for diverse cytokines

Xie, Meng; Li, Jin-Ping

Ingår i Cellular Signalling, s. 115-121, 2019

• DOI för Heparan sulfate proteoglycan - A common receptor for diverse cytokines

Upregulated BMP-Smad signaling activity in the glucuronyl C5-epimerase knock out MEF cells

Batool, Tahira; Fang, Jianping; Jansson, Viktor; Zhao, Hongxing et al.

Ingår i Cellular Signalling, s. 122-129, 2019

• DOI för Upregulated BMP-Smad signaling activity in the glucuronyl C5-epimerase knock out MEF cells

Characterization of epimerization and composition of heparin and dalteparin using a UHPLC-ESI-MS/MS method

Zhang, Tianji; Liu, Xin; Li, Hongmei; Wang, Zhangjie et al.

Ingår i Carbohydrate Polymers, s. 87-94, 2019

• DOI för Characterization of epimerization and composition of heparin and dalteparin using a UHPLC-ESI-MS/MS method

Involvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications

Barash, Uri; Lapidot, Moshe; Zohar, Yaniv; Loomis, Cynthia et al.

Ingår i Journal of the National Cancer Institute, s. 1102-1114, 2018

• DOI för Involvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications

Overexpression of heparanase in mice promoted megakaryopoiesis

Tan, Ying-Xia; Cui, Hao; Wan, Lu-Ming; Gong, Feng et al.

Ingår i Glycobiology, s. 269-275, 2018

• DOI för Overexpression of heparanase in mice promoted megakaryopoiesis

Overexpression of heparanase attenuated TGF-beta-stimulated signaling in tumor cells

Batool, Tahira; Fang, Jianping; Barash, Uri; Moustakas, Aristidis et al.

Ingår i FEBS Open Bio, s. 405-413, 2017

• DOI för Overexpression of heparanase attenuated TGF-beta-stimulated signaling in tumor cells
• Ladda ner fulltext (pdf) av Overexpression of heparanase attenuated TGF-beta-stimulated signaling in tumor cells

Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway

Pfankuchen, Daniel Bastian; Baltes, Fabian; Batool, Tahira; Li, Jin-Ping et al.

Ingår i Oncotarget, s. 67553-67566, 2017

• DOI för Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway
• Ladda ner fulltext (pdf) av Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway

Gubenyiliu II Inhibits Breast Tumor Growth and Metastasis Associated with Decreased Heparanase Expression and Phosphorylation of ERK and AKT Pathways

Zhang, Yi; Zhang, Gan-Lin; Sun, Xu; Cao, Ke-Xin et al.

Ingår i Molecules, 2017

• DOI för Gubenyiliu II Inhibits Breast Tumor Growth and Metastasis Associated with Decreased Heparanase Expression and Phosphorylation of ERK and AKT Pathways
• Ladda ner fulltext (pdf) av Gubenyiliu II Inhibits Breast Tumor Growth and Metastasis Associated with Decreased Heparanase Expression and Phosphorylation of ERK and AKT Pathways

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

Gustafsen, Camilla; Olsen, Ditte; Vilstrup, Joachim; Lund, Signe et al.

Ingår i Nature Communications, 2017

• DOI för Heparan sulfate proteoglycans present PCSK9 to the LDL receptor
• Ladda ner fulltext (pdf) av Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis

Digre, Andreas; Singh, Kailash; Åbrink, Magnus; Reijmers, Rogier M. et al.

Ingår i Scientific Reports, 2017

• DOI för Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis
• Ladda ner fulltext (pdf) av Overexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis

Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Xiong, Anqi; Kundu, Soumi; Forsberg, Maud; Xiong, Yuyuan et al.

Ingår i Matrix Biology, s. 92-104, 2017

• DOI för Heparanase confers a growth advantage to differentiating murine embryonic stem cells, and enhances oligodendrocyte formation.

Overexpression of heparanase attenuated TGF-beta-stimulated signaling in tumor cells

Batool, Tahira; Fang, Jianping; Barash, Uri; Moustakas, Aristidis et al.

Ingår i International journal of experimental pathology (Print), 2017

Dual roles of heparanase in vascular calcification associated with human carotid atherosclerosis

Aldi, S.; Eriksson, L.; Kronqvist, M.; Lengquist, M. et al.

Ingår i International journal of experimental pathology (Print), 2017

Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase

Zhang, Yi; Sun, Xu; Nan, Nan; Cao, Ke-Xin et al.

Ingår i Molecular Medicine Reports, s. 794-800, 2017

• DOI för Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase

Heparin interactions with apoA1 and SAA in inflammation-associated HDL

Digre, Andreas; Nan, Jie; Frank, Martin; Li, Jin-Ping

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 309-314, 2016

• DOI för Heparin interactions with apoA1 and SAA in inflammation-associated HDL

Heparanase expression upregulates platelet adhesion activity and thrombogenicity

Cui, Hao; Tan, Ying-xia; Österholm, Cecilia; Zhang, Xiao-Qun et al.

Ingår i Oncotarget, s. 39486-39496, 2016

• DOI för Heparanase expression upregulates platelet adhesion activity and thrombogenicity

Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis

Fang, Jianping; Song, Tianyi; Lindahl, Ulf; Li, Jin-Ping

Ingår i Scientific Reports, 2016

• DOI för Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis
• Ladda ner fulltext (pdf) av Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis

Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Kundu, Soumi; Xiong, Anqi; Spyrou, Argyris; Wicher, Grzegorz et al.

Ingår i Molecular Cancer Research, s. 1243-1253, 2016

• DOI för Heparanase Promotes Glioma Progression and is Inversely Correlated with Patient Survival.

Heparanase is required for activation and function of macrophages

Gutter-Kapon, Lilach; Alishekevitz, Dror; Shaked, Yuval; Li, Jin-Ping et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2016

• DOI för Heparanase is required for activation and function of macrophages

Spatholobus suberectus Column Extract Inhibits Estrogen Receptor Positive Breast Cancer via Suppressing ER MAPK PI3K/AKT Pathway

Sun, Jia-Qi; Zhang, Gan-Lin; Zhang, Yi; Nan, Nan et al.

Ingår i Evidence-based Complementary and Alternative Medicine, 2016

• DOI för Spatholobus suberectus Column Extract Inhibits Estrogen Receptor Positive Breast Cancer via Suppressing ER MAPK PI3K/AKT Pathway
• Ladda ner fulltext (pdf) av Spatholobus suberectus Column Extract Inhibits Estrogen Receptor Positive Breast Cancer via Suppressing ER MAPK PI3K/AKT Pathway

Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones

Dierker, Tabea; Bachvarova, Velina; Krause, Yvonne; Li, Jin-Ping et al.

Ingår i Matrix Biology, s. 82-92, 2016

• DOI för Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones

Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis

Garsen, Marjolein; Benner, Marilen; Dijkman, Henry B.; van Kuppevelt, Toin H. et al.

Ingår i American Journal of Pathology, s. 805-815, 2016

• DOI för Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis

Lung ICAM-1 and ICAM-2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin-inflamed lungs

Petrovich, Ekaterina; Feigelson, Sara W.; Stoler-Barak, Liat; Hatzav, Miki et al.

Ingår i The FASEB Journal, s. 1767-1778, 2016

• DOI för Lung ICAM-1 and ICAM-2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin-inflamed lungs

Overexpression of Heparanase Lowers the Amyloid Burden in Amyloid-beta Precursor Protein Transgenic Mice

Jendresen, Charlotte B.; Cui, Hao; Zhang, Xiao; Vlodavsky, Israel et al.

Ingår i Journal of Biological Chemistry, s. 5053-5064, 2015

• DOI för Overexpression of Heparanase Lowers the Amyloid Burden in Amyloid-beta Precursor Protein Transgenic Mice

Structural and Functional Study of D-Glucuronyl C5-epimerase

Qin, Yi; Ke, Jiyuan; Gu, Xin; Fang, Jianping et al.

Ingår i Journal of Biological Chemistry, s. 4620-4630, 2015

• DOI för Structural and Functional Study of D-Glucuronyl C5-epimerase

The Role of Heparanase in Pulmonary Cell Recruitment in Response to an Allergic but Not Non-Allergic Stimulus

Morris, Abigail; Wang, Bo; Waern, Ida; Venkatasamy, Radhakrishnan et al.

Ingår i PLOS ONE, 2015

• DOI för The Role of Heparanase in Pulmonary Cell Recruitment in Response to an Allergic but Not Non-Allergic Stimulus
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Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

Oskarsson, Marie E.; Singh, Kailash; Wang, Jian; Vlodavsky, Israel et al.

Ingår i Journal of Biological Chemistry, s. 15121-15132, 2015

• DOI för Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response

O'Callaghan, Paul; Li, Jin-Ping; Lannfelt, Lars; Lindahl, Ulf et al.

Ingår i Journal of Biological Chemistry, s. 14904-14914, 2015

• DOI för Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response

Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways

O'Callaghan, Paul; Noborn, Fredrik; Sehlin, Dag; Li, Jin-ping et al.

Ingår i Amyloid, s. 76-87, 2014

• DOI för Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways

Novel peptides that inhibit heparanase activation of the coagulation system

Axelman, Elena; Henig, Israel; Crispel, Yonatan; Attias, Judith et al.

Ingår i Thrombosis and Haemostasis, s. 466-477, 2014

• DOI för Novel peptides that inhibit heparanase activation of the coagulation system

Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors

Hunter, K. E.; Palermo, C.; Kester, J. C.; Simpson, K. et al.

Ingår i Oncogene, s. 1799-1808, 2014

• DOI för Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors

Role of Heparanase-Driven Inflammatory Cascade in Pathogenesis of Diabetic Nephropathy

Goldberg, Rachel; Rubinstein, Ariel M.; Gil, Natali; Hermano, Esther et al.

Ingår i Diabetes, s. 4302-4313, 2014

• DOI för Role of Heparanase-Driven Inflammatory Cascade in Pathogenesis of Diabetic Nephropathy

Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis

Boyango, Ilanit; Barash, Uri; Naroditsky, Inna; Li, Jin-Ping et al.

Ingår i Cancer Research, s. 4504-4514, 2014

• DOI för Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis

Characterization of Heparanase-induced Phosphatidylinositol 3-Kinase-AKT Activation and Its Integrin Dependence

Riaz, Anjum; Ilan, Neta; Vlodavsky, Israel; Li, Jin-Ping et al.

Ingår i Journal of Biological Chemistry, s. 12366-12375, 2013

• DOI för Characterization of Heparanase-induced Phosphatidylinositol 3-Kinase-AKT Activation and Its Integrin Dependence

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

Christianson, Helena C.; Svensson, Katrin J.; van Kuppevelt, Toin H.; Li, Jin-Ping et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 17380-17385, 2013

• DOI för Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

Increased expression of heparanase in symptomatic carotid atherosclerosis

Österholm, C.; Folkersen, L.; Lengquist, M.; Pontén, Fredrik et al.

Ingår i Atherosclerosis, s. 67-73, 2013

• DOI för Increased expression of heparanase in symptomatic carotid atherosclerosis

A Novel Bacterial Enzyme with D-Glucuronyl C5-epimerase Activity

Raedts, John; Lundgren, Magnus; Kengen, Serve W. M.; Li, Jin-Ping et al.

Ingår i Journal of Biological Chemistry, s. 24332-24339, 2013

• DOI för A Novel Bacterial Enzyme with D-Glucuronyl C5-epimerase Activity

Heparan sulfate/heparin-HDL interaction dissociates serum amyloid A (SAA) from HDL-SAA complex leading to SAA aggregation

Noborn, Fredrik; Ancsin, John; Ubhayasekera, Wimal; Kisilevsky, Robert et al.

Ingår i Journal of Biological Chemistry, s. 25669-25677, 2012

• DOI för Heparan sulfate/heparin-HDL interaction dissociates serum amyloid A (SAA) from HDL-SAA complex leading to SAA aggregation

Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-beta in murine brain

Zhang, Xiao; Wang, Bo; O'Callaghan, Paul; Hjertstrom, Elina et al.

Ingår i Acta Neuropathologica, s. 465-478, 2012

• DOI för Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-beta in murine brain

Accelerated resolution of AA amyloid in heparanase knockout mice is associated with matrix metalloproteases

Wang, Bo; Tan, Ying-Xia; Jia, Juan; Digre, Andreas et al.

Ingår i PLOS ONE, 2012

• DOI för Accelerated resolution of AA amyloid in heparanase knockout mice is associated with matrix metalloproteases
• Ladda ner fulltext (pdf) av Accelerated resolution of AA amyloid in heparanase knockout mice is associated with matrix metalloproteases

Heparanase Affects Food Intake and Regulates Energy Balance in Mice

Karlsson-Lindahl, Linda; Schmidt, Linnea; Haage, David; Hansson, Caroline et al.

Ingår i PLOS ONE, 2012

• DOI för Heparanase Affects Food Intake and Regulates Energy Balance in Mice
• Ladda ner fulltext (pdf) av Heparanase Affects Food Intake and Regulates Energy Balance in Mice

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

Gil, Natali; Goldberg, Rachel; Neuman, Tzahi; Garsen, Marjolein et al.

Ingår i Diabetes, s. 208-216, 2012

• DOI för Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice

Li, Lili; Wang, Bo; Gao, Tianle; Zhang, Xiao et al.

Ingår i Neuroscience Letters, s. 4-7, 2012

• DOI för Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice

Expression of heparanase in vascular cells and astrocytes of the mouse brain after focal cerebral ischemia

Li, Jimei; Li, Jin-Ping; Zhang, Xiao; Lu, Zhongyang et al.

Ingår i Brain Research, s. 137-144, 2012

• DOI för Expression of heparanase in vascular cells and astrocytes of the mouse brain after focal cerebral ischemia

Heparan Sulfate Biosynthesis Enzymes in Embryonic Stem Cell Biology

Tamm, Christoffer; Kjellén, Lena; Li, Jin-Ping

Ingår i Journal of Histochemistry and Cytochemistry, s. 943-949, 2012

• DOI för Heparan Sulfate Biosynthesis Enzymes in Embryonic Stem Cell Biology

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein

Noborn, Fredrik; O'Callaghan, Paul; Hermansson, Erik; Zhang, Xiao et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 5584-5589, 2011

• DOI för Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein

Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo

Zhou, Ping; Zhai, Shanli; Zhou, Xiang; Lin, Ping et al.

Ingår i International Journal of Biological Sciences, s. 947-959, 2011

Heparanase Modulation of Early Growth Response Gene Expression

Yan, Xia; Jin, Sihu; Li, Subo; Gong, Feng et al.

Ingår i Zoological Science, s. 189-194, 2011

• DOI för Heparanase Modulation of Early Growth Response Gene Expression

Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival

Reijmers, Rogier M.; Groen, Richard W. J.; Kuil, Annemieke; Weijer, Kees et al.

Ingår i Blood, s. 6162-6171, 2011

• DOI för Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival

Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparin

Wang, Bo; Jia, Juan; Zhang, Xiao; Zcharia, Eyal et al.

Ingår i Journal of Allergy and Clinical Immunology, s. 1310-131700000000, 2011

• DOI för Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparin

The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease

Smits, Nicole C.; Kurup, Sindhulakshmi; Rops, Angelique L.; Ten Dam, Gerdy B. et al.

Ingår i Journal of Biological Chemistry, s. 41143-41151, 2010

• DOI för The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease

Amino acid substitutions in the E2 glycoprotein of Sindbis-like virus XJ-160 confer the ability to undergo heparan sulfate-dependent infection of mouse embryonic fibroblasts

Zhu, Wuyang; Fu, Shihong; He, Ying; Li, Jin-Ping et al.

Ingår i Virology Journal, s. 225, 2010

• DOI för Amino acid substitutions in the E2 glycoprotein of Sindbis-like virus XJ-160 confer the ability to undergo heparan sulfate-dependent infection of mouse embryonic fibroblasts

Heparan sulfate mediates amyloid-beta internalization and cytotoxicity

Sandwall, Elina; O'Callaghan, Paul; Zhang, Xiao; Lindahl, Ulf et al.

Ingår i Glycobiology, s. 533-541, 2010

• DOI för Heparan sulfate mediates amyloid-beta internalization and cytotoxicity

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

Massena, Sara; Christoffersson, Gustaf; Hjertström, Elina; Zcharia, Eyal et al.

Ingår i Blood, s. 1924-1931, 2010

• DOI för A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

Interaction of E2 glycoprotein with heparan sulfate is crucial for cellular infection of Sindbis virus

Zhu, Wuyang; Wang, Lihua; Yang, Yiliang; Jia, Juan et al.

Ingår i PLoS ONE, 2010

• DOI för Interaction of E2 glycoprotein with heparan sulfate is crucial for cellular infection of Sindbis virus

Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase

Waern, Ida; Jia, Juan; Pejler, Gunnar; Zcharia, Eyal et al.

Ingår i Molecular Immunology, s. 1467-1475, 2010

• DOI för Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase

Changes of learning and memory ability and brain nicotinic receptors of rat offspring with coal burning fluorosis

Gui, Chuan-Zhi; Ran, Long-Yan; Li, Jin-Ping; Guan, Zhi-Zhong

Ingår i Neurotoxicology and Teratology, s. 536-541, 2010

• DOI för Changes of learning and memory ability and brain nicotinic receptors of rat offspring with coal burning fluorosis

Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase

Reijmers, Rogier M; Vondenhoff, Mark F R; Roozendaal, Ramon; Kuil, Annemieke et al.

Ingår i Journal of Immunology, s. 3656-3664, 2010

• DOI för Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase

Heparin, heparan sulfate and heparanase in inflammatory reactions

Li, Jin-Ping; Vlodavsky, Israel

Ingår i Thrombosis and Haemostasis, s. 823-828, 2009

• DOI för Heparin, heparan sulfate and heparanase in inflammatory reactions

Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases

Zcharia, Eyal; Jia, Juan; Zhang, Xiao; Baraz, Lea et al.

Ingår i PLoS ONE, 2009

• DOI för Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases

Lack of L-iduronic acid in heparan sulfate affects interaction with growth factors and cell signaling

Jia, Juan; Maccarana, Marco; Zhang, Xiao; Bespalov, Maxim et al.

Ingår i Journal of Biological Chemistry, s. 15942-15950, 2009

• DOI för Lack of L-iduronic acid in heparan sulfate affects interaction with growth factors and cell signaling

Molecular Structure of Heparan Sulfate from Spalax: IMPLICATIONS OF HEPARANASE AND HYPOXIA.

Sandwall, Elina; Bodevin, Sabrina; Nasser, Nicola J; Nevo, Eviatar et al.

Ingår i Journal of Biological Chemistry, s. 3814-3822, 2009

• DOI för Molecular Structure of Heparan Sulfate from Spalax: IMPLICATIONS OF HEPARANASE AND HYPOXIA.

Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells

O'Callaghan, Paul; Sandwall, Elina; Li, Jin-Ping; Yu, Hong et al.

Ingår i Brain Pathology, s. 548-561, 2008

• DOI för Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells

Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function

Bode, Lars; Salvestrini, Camilla; Park, Pyong Woo; Li, Jin-Ping et al.

Ingår i Journal of Clinical Investigation, s. 229-238, 2008

• DOI för Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function

Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria

van den Hoven, M J; Wijnhoven, T J; Li, Jin-Ping; Zcharia, E et al.

Ingår i Kidney International, s. 278-287, 2008

• DOI för Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Abramsson, Alexandra; Kurup, Sindhulakshmi; Yamada, Shuhei; Lindblom, Per et al.

Ingår i Genes & Development, s. 316-331, 2007

• DOI för Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Characterization of anti-heparan sulfate phage display antibodies AO4B08 and HS4E4

Kurup, Sindhulakshmi; Wijnhoven, Tessa J M; Jenniskens, Guido J; Kimata, Koji et al.

Ingår i Journal of Biological Chemistry, s. 21032-21042, 2007

• DOI för Characterization of anti-heparan sulfate phage display antibodies AO4B08 and HS4E4

Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis

Yang, Yang; Macleod, Veronica; Miao, Hua-Quan; Theus, Allison et al.

Ingår i Journal of Biological Chemistry, s. 13326-13333, 2007

• DOI för Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis

Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate

Escobar Galvis, Martha L.; Jia, Juan; Zhang, Xiao; Jastrebova, Nadja et al.

Ingår i Nature Chemical Biology, s. 773-778, 2007

• DOI för Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate

Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin

Nasser, N J; Sarig, G; Brenner, B; Nevo, E et al.

Ingår i Journal of Thrombosis and Haemostasis, s. 560-565, 2006

• DOI för Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin

Heparan sulphate requirement in platelet-derived growth factor B-mediated pericyte recruitment

Kurup, S; Abramsson, A; Li, Jin-Ping; Lindahl, Ulf et al.

Ingår i Biochemical Society Transactions, s. 454-455, 2006

Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5-epimerase is identical to SART2.

Maccarana, Marco; Olander, Benny; Malmström, Johan; Tiedemann, Kerstin et al.

Ingår i J Biol Chem, s. 11560-8, 2006

Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells.

Feyerabend, Thorsten B; Li, Jin-Ping; Lindahl, Ulf; Rodewald, Hans-Reimer

Ingår i Nat Chem Biol, s. 195-6, 2006

In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis

Li, Jin-Ping; Galvis, Martha L. Escobar; Gong, Feng; Zhang, Xiao et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 6473-7, 2005

• DOI för In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis

Mutational study of human phosphohistidine phosphatase: effect on enzymatic activity.

Ma, Ruixin; Kanders, Erik; Sundh, Ulla Beckman; Geng, Meiyu et al.

Ingår i Biochem Biophys Res Commun, s. 887-91, 2005

Generation of "neoheparin" from E. coli K5 capsular polysaccharide.

Lindahl, Ulf; Li, Jin-Ping; Kusche-Gullberg, Marion; Salmivirta, Markku et al.

Ingår i J Med Chem, s. 349-52, 2005

Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior.

Zcharia, Eyal; Metzger, Shula; Chajek-Shaul, Tova; Aingorn, Helena et al.

Ingår i FASEB J, s. 252-63, 2004

Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate.

Hagner-McWhirter, Asa; Li, Jin-Ping; Oscarson, Stefan; Lindahl, Ulf

Ingår i J Biol Chem, s. 14631-8, 2004

Heparan sulfate structure in mice with genetically modified heparan sulfate production.

Ledin, Johan; Staatz, William; Li, Jin-Ping; Götte, Martin et al.

Ingår i J Biol Chem, s. 42732-41, 2004

Processing of macromolecular heparin by heparanase

Gong, Feng; Jemth, Per; Escobar Galvis, Martha L; Vlodavsky, Israel et al.

Ingår i Journal of Biological Chemistry, s. 35152-35158, 2003

• DOI för Processing of macromolecular heparin by heparanase

Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase

Ek, Pia; Zetterqvist, Örjan; Li, Jin-Ping; Ek, Bo et al.

Ingår i European Journal of Biochemistry, s. 5016-5023, 2002

• DOI för Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase
• Ladda ner fulltext (pdf) av Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase

Substrate specificity of heparanases from human hepatoma and platelets

Sandbäck Pikas, Dagmar; Li, Jin-Ping; Vlodavsky, I; Lindahl, Ulf

Ingår i Journal of chemical biology, s. 18770-18777, 1998

• DOI för Substrate specificity of heparanases from human hepatoma and platelets

Biosynthesis of heparin / heparan sulfate: cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung

Li, Jin-Ping; Hagner-McWhirther, Åsa; Kjellén, Lena; Palgi, Jaan et al.

Ingår i Journal of Biological Chemistry, s. 28158-28163, 1997

• DOI för Biosynthesis of heparin / heparan sulfate: cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung

Streptomyces: boost chassis strains for production of invaluable natural products

Chen, Simin; Ling, Siqi; Li, Jinpin; Liu, Zhiyan et al.

Ingår i SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, s. 515-535, 2026

• DOI för Streptomyces: boost chassis strains for production of invaluable natural products
• Ladda ner fulltext (pdf) av Streptomyces: boost chassis strains for production of invaluable natural products

Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review

Wu, Yiyang; Zhao, Siran; Wang, Jiandong; Chen, Yujuan et al.

Ingår i International Journal of Biological Macromolecules, 2024

• DOI för Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review
• Ladda ner fulltext (pdf) av Methods for determining the structure and physicochemical properties of hyaluronic acid and its derivatives: A review

Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism

McMillan, Ilayda Ozsan; Li, Jin-Ping; Wang, Lianchun

Ingår i American Journal of Physiology - Cell Physiology, 2023

• DOI för Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism

Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing

Jiang, Lan; Zhang, Tianji; Lu, Hongzhong; Li, Saijuan et al.

Ingår i SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, s. 11-19, 2023

• DOI för Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing
• Ladda ner fulltext (pdf) av Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing

Is heparan sulfate a target for inhibition of RNA virus infection?

Ling, Jiaxin; Li, Jinlin; Khan, Asifa; Lundkvist, Åke et al.

Ingår i American Journal of Physiology - Cell Physiology, 2022

• DOI för Is heparan sulfate a target for inhibition of RNA virus infection?

Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic

Yu, Mingjia; Zhang, Tianji; Zhang, Wei; Sun, Qianyun et al.

Ingår i Frontiers in Molecular Biosciences, 2021

• DOI för Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic
• Ladda ner fulltext (pdf) av Elucidating the Interactions Between Heparin/Heparan Sulfate and SARS-CoV-2-Related Proteins: An Important Strategy for Developing Novel Therapeutics for the COVID-19 Pandemic

Comprehensive Landscape of Heparin Therapy for COVID-19

Shi, Chen; Tingting, Wu; Li, Jin-Ping; Sullivan, Mitchell A. et al.

Ingår i Carbohydrate Polymers, 2021

• DOI för Comprehensive Landscape of Heparin Therapy for COVID-19

Glycosaminoglycans in biological samples: towards identification of novel biomarkers

Zhang, Tianji; Zhang, Rui; Lv, Yongqin; Wang, Meng et al.

Ingår i TrAC. Trends in analytical chemistry, 2020

• DOI för Glycosaminoglycans in biological samples: towards identification of novel biomarkers

Selective binding of heparin oligosaccharides in a magnetic thermoresponsive molecularly imprinted polymer

Zhang, Rui; Zhang, Tianji; Lv, Yongqin; Qin, Peiyong et al.

Ingår i Talanta, s. 441-449, 2019

• DOI för Selective binding of heparin oligosaccharides in a magnetic thermoresponsive molecularly imprinted polymer

Role of proteoglycans in neuro-inflammation and central nervous system fibrosis

Heindryckx, Femke; Li, Jin-Ping

Ingår i Matrix Biology, s. 589-601, 2018

• DOI för Role of proteoglycans in neuro-inflammation and central nervous system fibrosis

Heparan Sulfate Proteoglycans as Relays of Neuroinflammation

O'Callaghan, Paul; Zhang, Xiao; Li, Jin-Ping

Ingår i Journal of Histochemistry and Cytochemistry, s. 305-319, 2018

• DOI för Heparan Sulfate Proteoglycans as Relays of Neuroinflammation

Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data

Sun, Xu; Zhang, Ganlin; Nian, Jiayun; Yu, Mingwei et al.

Ingår i Oncotarget, s. 43521-43535, 2017

• DOI för Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data
• Ladda ner fulltext (pdf) av Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data

Chinese Herbal Medicine as Adjunctive Therapy to Chemotherapy for Breast Cancer: A Systematic Review and Meta-Analysis

Sun, Xu; Zhang, Xing; Nian, Jia-Yun; Guo, Jiao et al.

Ingår i Evidence-based Complementary and Alternative Medicine, 2016

• DOI för Chinese Herbal Medicine as Adjunctive Therapy to Chemotherapy for Breast Cancer: A Systematic Review and Meta-Analysis
• Ladda ner fulltext (pdf) av Chinese Herbal Medicine as Adjunctive Therapy to Chemotherapy for Breast Cancer: A Systematic Review and Meta-Analysis

Implications of heparan sulfate and heparanase in neuroinflammation

Zhang, Xiao; Wang, Bo; Li, Jin-Ping

Ingår i Matrix Biology, s. 174-181, 2014

• DOI för Implications of heparan sulfate and heparanase in neuroinflammation

Towards Understanding the Roles of Heparan Sulfate Proteoglycans in Alzheimer's Disease

Zhang, Gan-lin; Zhang, Xiao; Wang, Xiao-min; Li, Jin-Ping

Ingår i BioMed Research International, s. 516028, 2014

• DOI för Towards Understanding the Roles of Heparan Sulfate Proteoglycans in Alzheimer's Disease
• Ladda ner fulltext (pdf) av Towards Understanding the Roles of Heparan Sulfate Proteoglycans in Alzheimer's Disease

Involvement of heparanase in atherosclerosis and other vessel wall pathologies

Vlodavsky, Israel; Blich, Miry; Li, Jin-Ping; Sanderson, Ralph D. et al.

Ingår i Matrix Biology, s. 241-251, 2013

• DOI för Involvement of heparanase in atherosclerosis and other vessel wall pathologies

Heparan sulfate proteoglycans in amyloidosis.

Zhang, Xiao; Li, Jin-Ping

Ingår i Progress in molecular biology and translational science, s. 309-334, 2010

• DOI för Heparan sulfate proteoglycans in amyloidosis.

Glucuronyl C5-epimerase: an enzyme converting glucuronic acid to iduronic acid in heparan sulfate/heparin biosynthesis

Li, Jin-ping

Ingår i Progress in molecular biology and translational science, s. 59-78, 2010

• DOI för Glucuronyl C5-epimerase: an enzyme converting glucuronic acid to iduronic acid in heparan sulfate/heparin biosynthesis

Interactions Between Heparan Sulfate and Proteins—Design and Functional Implications

Lindahl, Ulf; Li, Jin-ping

Ingår i International review of cell and molecular biology, s. 105-159, 2009

• DOI för Interactions Between Heparan Sulfate and Proteins—Design and Functional Implications

Heparin, heparan sulfate and heparanase in cancer: remedy for metastasis?

Li, Jin-Ping

Ingår i Anti-Cancer Agents in Medicinal Chemistry, s. 64-76, 2008

• DOI för Heparin, heparan sulfate and heparanase in cancer: remedy for metastasis?

Interactions between heparan sulfate and proteins: the concept of specificity

Kreuger, Johan; Spillmann, Dorothe; Li, Jin-ping; Lindahl, Ulf

Ingår i Journal of Cell Biology, s. 323-327, 2006

Heparanase: Discovery and Targets

Lindahl, Ulf; Li, Jin-Ping

Ingår i Heparanase, s. 61-69, Springer, 2020

• DOI för Heparanase: Discovery and Targets

Heparan Sulfate: Biosynthesis, Structure, and Function

Li, Jin-ping; Kusche-Gullberg, M.

Ingår i International Review Of Cell And Molecular Biology, Vol 325, s. 215-273, Elsevier, 2016

• DOI för Heparan Sulfate: Biosynthesis, Structure, and Function

Functions of Heparan Sulfate Proteoglycans in Development: Insights From Drosophila Models

Nakato, H.; Li, Jin-ping

Ingår i International Review Of Cell And Molecular Biology, Vol 325, s. 275-293, Elsevier, 2016

• DOI för Functions of Heparan Sulfate Proteoglycans in Development: Insights From Drosophila Models

Heparanase, a multifaceted protein involved in cancer, chronic inflammation, and kidney dysfunction

Vlodavsky, I; Elkin, M; Casu, B; Li, Jin-Ping et al.

Ingår i Extracellular Matrix, s. 833-864, De Gruyter, 2012

Heparan sulfate proteoglycans as multifunctional cell regulators: cell surface receptors

Li, Jin-ping; Spillmann, Dorothe

Ingår i Proteoglycans, s. 239-255, Springer, 2012

• DOI för Heparan sulfate proteoglycans as multifunctional cell regulators: cell surface receptors

D-glucuronyl C5-epimerase in heparin/heparan sulfate biosynthesis

Li, Jin-Ping; Lindahl, Ulf

Ingår i Handbook of glycosyltransferases and related genes, s. 403-409, Springer, 2002

Substrate recognition by heparanase

Sandbäck Pikas, Dagmar; Vlodavsky, I; Lindahl, Ulf; Li, Jin-Ping

Ingår i GLYCO XIII: XIIIth International Symposium on Glycoconjugates, seattle, USA,  August 20-26, 1995

Heparanase cleavage of heparin modulates protease storage in mast cells

Jia, Juan; Zhang, Xiao; Zcharia, Eyal; Vlodavsky, Israel et al.

Heparan sulfate - an information package?

Feyzi, E; Lindahl, B; Spillmann, Dorothe; Salmivirta, M et al.

Ingår i Glycoconjugate Journal, s. 14, 1997